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PubMed1994

Polycythemia associated with uterine fibroid.

Polycythemia has been observed to occur infrequently in association with uterine fibromyomas. Study of this case revealed polycythemia prior to surgery and remission was noted after myomectomy. The mechanisms proposed to explain polycythemia in such a tumor were revised.

Adult↗
PubMed1994

The effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study.

OBJECTIVE: Our purpose was to examine the effects of RU 486 and leuprolide acetate on uterine artery blood flow and uterine volume. STUDY DESIGN: Patients were randomly assigned to group A (eight patients) receiving 25 mg of RU 486 daily for 3 months or group B (six patients) receiving 3.75 mg of leuprolide acetate monthly for 3 months. Uterine artery blood flow change was determined by resistive index by means of vaginal color Doppler ultrasonography. Uterine volume was measured before and during the study with abdominal ultrasonography. RESULTS: Both groups showed an increase in resistive index. Patients receiving RU 486 had uterine artery blood flow decreased by 40%, and those receiving leuprolide acetate had a 21% decrease. We noted a significant decrease in uterine volume compared with pretreatment in both groups at 3 months. There was no significant decrease between groups. CONCLUSION: Both RU 486 (25 mg daily) and leuprolide acetate (3.75 mg monthly) are effective in decreasing blood flow to the uterus (increasing resistive index) and decreasing uterine volume at 3 months. A significant decrease in uterine artery blood flow may provide a mechanism for the decrease in uterine size and the decrease in uterine blood loss at the time of surgery.

Female↗
PubMed1993

Facing fibroids.

Explore the source record for details and available documents.

Female↗
PubMed1993

Management of the symptomatic fibroid in women older than 40 years of age. Hysterectomy or myomectomy?

Although complications resulting from a myomectomy are infrequent, the overall risk is probably greater than a hysterectomy. The effect of hysterectomy on the specific women is difficult to quantify, however. Supracervical hysterectomy is a reasonable alternative in the woman with a normal cervix. Moreover, repeated laparotomies are not particularly advisable. In a woman who has previously undergone a myomectomy and has had a recurrent symptomatic myomatous uterus, the decision must be made either to proceed with a repeat myomectomy or to perform a hysterectomy. The chance of successfully achieving a pregnancy after a second myomectomy may be less favorable than after a primary myomectomy. A myomectomy can be a difficult and often time-consuming procedure. With meticulous attention to technique, however, the procedure can be accomplished safely and effectively with relatively ensured hemostasis and minimal blood loss. A myomectomy affords the option of preserving the uterus in those patients with symptomatic uterine myomata who desire to preserve their reproductive organs. However, careful assessment with meticulous counseling of the patient is essential. The potential option for a hysterectomy must always be preserved. Hysteroscopic resection of submucous myomata with endometrial ablation has become the technique of preference in many cases. At the moment, abdominal myomectomy is the preferred technique for the removal of intramural and subserosal myomata. For the present, laparoscopic myomectomy must be viewed as being of very limited acceptability.

Female↗
PubMed1995

Uterine fibroids. Diagnosis and indications for treatment.

Although uterine myomas are extremely common, the majority are asymptomatic and therefore require no treatment. Pelvic ultrasound, hysteroscopy, and infrequently MR imaging are useful in the confirmation of this diagnosis especially when long-term expectant management is to be used. Many indicators previously recommended for treatment are empiric in nature and have been discarded in modern times. Current standards dictate that prophylactic intervention seldom is warranted.

Abortion, Habitual↗