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[Primary carcinoma of the Fallopian tube--a clinical study of 37 cases (author's transl)].

Thirty-seven cases of primary fallopian tube carcinoma treated at our institution over the years 1946 to 1976 are described. The overall 5-years survival rate was 30%, although patients with early tumors had 42% survival rate. The single most important factor affecting survival appeared to be the extent of disease at the time of diagnosis. Present treatment modalities are discussed, even though the number of tube carcinomas are few, it might be useful to adopt an official classification.

Adult↗

Spontaneous periodic contraction of the ampullar segment of the human fallopian tube in vitro.

Spontaneous mechanical activity of 36 segments from the ampullar part of human Fallopian tubes was studied in vitro. The age of the patients varied between 37-64 years. Outer diameter and axial tension were continuously measured at an intraluminal pressure of 5 mmHg (0.67 kPa) and at 10% axial extension. All segments have shown periodic contractions both in diameter and axial tension. The amplitude of the outer diameter contractions was 0.03-0.64 mm, the frequencies were between 1.5 and 7.3 min-1. The amplitude of the axial tension contractions was 1.87-33.2 mN, the frequencies varied between 1.8 and 7.6 min-1. The diameter and axial tension contractions were mostly synchronized. The frequency of the basal rhythm increased with age. Increase of the intraluminal pressure up to 15 mmHg (2.0 kPa) significantly increased the diameter and decreased the amplitude of diameter contractions. Increase in the axial length significantly decreased the outer diameter and the amplitude of diameter contractions; it also increased axial tension, and caused a transitory increase in frequency.

Adult↗

Characterization and localization of estrogen and progesterone receptors of human fallopian tube.

The cellular distribution of estrogen and progesterone receptors (ER and PR) in the human fallopian tube was investigated by immunohistochemical localization with specific monoclonal antibodies. Nuclear immunostaining was observed. Intense PR immunostaining was seen in tissues obtained at mid cycle and luteal stages of the normal menstrual cycle. On the other hand, enhanced staining for ER was seen in early follicular phase and mid cycle. Menopausal tissues showed negligible staining for both ER and PR. The ER and PR were characterized for their molecular size, anatomical distribution and levels during the menstrual cycle and in menopause. ER protein was present throughout the cycle and also during menopause. Western blot analysis revealed two forms of ER approximately 66 kDa and a truncated from approximately 49 kDa in hFT. Presence of A [approximately 90 kDa] and B [approximately 120 kDa] isoforms of human PR was detected. Follicular and early luteal tissue possessed relatively high concentration of immunoreactive PR whereas it was almost undetectable in menopausal tissues. These results suggests that ER and PR are regulated by the changing ovarian steroid hormones.

Fallopian Tubes↗

Term pregnancy after fallopian tube transposition.

A 28-year-old woman suffered from pelvic pain and secondary infertility. She previously had right salpingo-oophorectomy because of ruptured right cornual EP. She was found to have a normal appearing left fallopian tube that entered into a noncommunicating residual horn of the uterus. Microsurgical transposition of the left tube and tubouterine implantation was performed successfully. For cases in which tubocornual anastomosis of the transposed tube is impossible because of previous cornual resection, our technique remains an option.

Adult↗