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At least 991 records · Page 55Linked to original sources
PubMed1987

Deaths from exertional myopathy at the National Zoological Park from 1975 to 1985.

A retrospective study was conducted to determine the incidence of deaths from exertional myopathy (EM) in the hoofstock collection at the National Zoological Park (NZP) from 1975 to 1985. The diagnosis of EM was based on history, clinical signs, clinicopathological findings, gross and microscopic lesions. Only bovids, cervids, and equids were included in the study. Data were derived from the medical and pathological records of the NZP. There were 10 cases of EM during this period, but only seven deaths were directly attributable to EM. Five deaths occurred after immobilization. Two deaths occurred after improper transport, but the anesthetic history was not known in these cases. Pathologic changes consistent with EM were incidental findings in an animal killed by dogs, and in two animals euthanized because of suspected infection with Parelaphostrongylus tenuis. Only cervids and bovids were affected. There was no age or sex predilection for developing EM and deaths occurred throughout the year. Deaths associated with immobilization occurred most often after anesthesia with xylazine and etorphine. These are the drugs used most frequently in bovid and cervid anesthesia at the NZP. The overall incidence of deaths from EM after immobilization was 0.25% for the 10-yr period.

Animals↗
PubMed1999

Exertional myopathy in translocated river otters from New York.

Lesions consistent with exertional myopathy (EM) were documented postmortem in four North American river otters (Lutra canadensis) during translocation for a population restoration project. Clinical signs in these otters included depression, anorexia and shock. Gross lesions in one otter included locally extensive linear, pale areas within the subscapularis, rectus abdominis, quadriceps, and dorsal laryngeal muscles. Microscopic lesions were characterized by acute to subacute myofiber necrosis of varying severity, and occurred in a variety of skeletal muscles as well as cardiac muscle in one otter. Based on these observations, we conducted a retrospective review of records of otters which experienced similar capture, transfer, and holding protocols between 1995 and 1997, but with a successful outcome (n = 69). Significant elevations in serum aspartate aminotransferase (AST) and creatine kinase (CK) were observed in 19 (28%) of the otters, but may have been higher due to delayed sample collection from some otters. However, none of the otters with elevated enzymes exhibited clinical signs suggestive of EM. These findings indicate that river otters may develop EM when translocated, but many cases may be mild or clinically inapparent.

Animals↗
PubMed1999

Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis.

OBJECTIVE: To determine whether abnormal regulation of muscle contraction similar to that associated with malignant hyperthermia (MH) was evident in intact external intercostal muscle cells from Thoroughbreds with recurrent exertional rhabdomyolysis (RER). ANIMALS: 5 adult Thoroughbred horses with RER and 7 clinically normal adult Thoroughbred or mixed-breed horses. PROCEDURES: Twitch time course variables and contracture responses to various concentrations of potassium, caffeine, and halothane were measured in small bundles of intact external intercostal muscle cells from clinically normal horses and horses with RER. RESULTS: Threshold for significant contracture induced by potassium depolarization was lower for RER-affected muscles, compared with normal muscles, although the relationship between potassium concentration and membrane potential were not different. Thresholds for contracture induced by caffeine and halothane were also lower for RER-affected muscles, compared with normal muscles. Lower thresholds for caffeine- and halothane-induced contractures, as well as depolarization-elicited contractures, in RER-affected muscles suggest a defect in myoplasmic calcium regulation. CONCLUSIONS AND CLINICAL RELEVANCE: Regulation of muscle contraction is abnormal in Thoroughbreds with RER. The specific defect may be attributable to abnormal intracellular calcium regulation. Knowledge of the specific defect involved in RER may lead to improved prevention and treatment of RER-affected horses.

Anesthetics, Inhalation↗
PubMed1976

Cochlear and vestibular dysfunction resulting from physical exertion or environmental pressure changes.

Inner ear damage due to physical exertion or environmental pressure changes has been described only recently. According to Goodhill there are two possible mechanisms of injury: the explosive and the implosive. The former is triggered by increased C.S.F. pressure transmitted to the perilymph space; the latter by increased pressure in the middle ear transmitted to the perilymph space through the two windows. Sudden hearing loss or dizziness, or both, are the main symptoms. The diagnosis will be established by the history, the audiogram, and the electronystagmogram (ENG). The treatment is still controversial. As the formation of a fistula is a real possibility, an exploratory tympanotomy is suggestive on suspected cases. Due to the variety of symptoms every case has to be assessed individually. A detailed history is of utmost importance.

Adolescent↗
PubMed1999

The validity of ratings of perceived exertion for cross-modal regulation of swimming intensity.

BACKGROUND: This study examined the use of Borg's category Ratings of Perceived Exertion (RPE) scale for prescribing and self-regulating swimming intensity. Subjects were males and females (n = 19) ages nineteen to fifty-eight who regularly swam for fitness. EXPERIMENTAL DESIGNS: Subjects completed six trials. Each trial was separated by a minimum of forty-eight hours. Mean cycle ergometry heart rates at estimated RPE-overall 12 and 16 were compared to mean swimming heart rates at produced RPE-overall 12 and 16. Also, mean arm ergometry heart rates at estimated RPE-arms 12 and 16 were compared to mean swimming heart rates at produced RPE-arms 12 and 16. Cycling and arm ergometry anchor trials familiarized subjects with testing protocol and Borg's scale prior to estimation and production trials. Comparisons were made using a one-way ANOVA (alpha 0.05). RESULTS: Mean cycling heart rate at RPE-overall 16 was not significantly different from mean swimming heart rate at RPE-overall 16. Mean swimming heart rate was significantly greater than cycling heart rate at RPE-overall 12. Mean swimming heart rates at RPE-arms 12 and 16 were significantly greater than arm ergometry heart rates at RPE-arms 12 and 16. CONCLUSIONS: Results suggest that RPE-overall 16 may be useful in prescribing a higher exercise intensity for swimmers. However, adjustments from RPE-overall 12 are needed for establishing a lower intensity. Additionally, arm ergometry-based RPEs may require adjustments to be effective in prescribing and regulating swimming intensity. Results suggest that cycling and arm ergometry anchored RPE responses should be used with discretion when prescribing and regulating swimming intensity.

Adult↗
PubMed1999

[An attack of malignant hyperthermia caused by a combination of the effects of succinylcholine, increased physical exertion and alcohol abuse].

The authors submit the case-history of a 29-year-old man, followed up on account of liver steatosis with a toxic-nutritional etiology who developed, after previous increased physical exertion and alcohol abuse, fever associated with major muscular weakness. Gradually he developed an amental delirious state which was evaluated as suspect delirium tremens. Fever of 40-41 degrees C continued, the patient developed muscular rigidity, tremor and hypotension. After intubation during which succinylcholine was administered, the patient's condition deteriorated further with a rise of temperature and muscular rigidity. The patient developed acute renal failure with anuria and the necessity of repeated haemodialyses and severe acidosis of the mixed type on account of which he was intubated and switched to artificial ventilation. According to the case-history clinical and laboratory picture of the disease (extremely high creatine kinase activity, hyperkalaemia, acidosis, hepatorenal failure) malignant hyperthermia was suspected. After a single intravenous injection of sodium dantrolene, 2.5 mg/kg, the temperature dropped and within 24 hours the patient was afebrile. Gradually the acidosis improved, the blood pressure became stabilized and artificial ventilation was no longer used. The patient was discharged after 34 days in hospital in a state of cardiopulmonary compensation with mild polyuria but without signs of retention of nitrogenous substances with sideropenic anaemia and marginal creatine kinase and lactate dehydrogenase values. Within one month after discharge the laboratory values reached normal levels and only slight muscular weakness and greater fatiguability persisted.

Adult↗
PubMedDate not supplied

Chronic exertional compartment syndrome of the legs in adolescents.

We present our experience in the management and treatment of chronic exertional compartment syndrome (CECS) of the legs in 23 adolescents. Twenty-one patients were affected in the anteroexternal compartment, one in the deep posterior compartment, and one in both. Seventeen of the patients were in-line competitive skaters; the rest practiced soccer or athletics. Mean age at the time of diagnosis was 16 (range, 14-18) years, and the age at the onset of symptoms was 15 (range, 13-17) years. After a careful differential diagnosis, the diagnosis was established on the basis of clinical signs and symptoms and confirmed by intracompartmental pressure (ICP) measurements. Based on our results, the following criteria are considered to be adequate: baseline ICP (at rest) >10 mm Hg, >20 mm Hg 1 minute after stopping exercise, >20 mm Hg 5 minutes later, and >15 minutes to achieve ICP normalization. All patients but one accepted surgical treatment (complete subcutaneous fasciotomy). No major complication was observed and only one minor complication occurred. All patients returned to the practice of their sports without any symptomatology 6 weeks after the surgery (mean follow-up, 4.8 years). To date there have been no relapses.

Adolescent↗
PubMed2001

Dyspnoea exaggerated in the supine position and during exertion--diagnostic challenge.

The case of dyspnoea, exaggerated when in the supine position and during exertion, as a result of severe weakness of the diaphragm is reported. The aim of the study was to present a rare case of idiopathic bilateral diaphragmatic paresis (BDP) and to describe all the diagnostic procedures necessary to perform differential diagnostics. In order to establish the final diagnosis, chest radiography, haemodynamic evaluation of the circulatory system, ultrasonography, ultrasonocardiography, measurement of transdiaphragmatic pressures, scintiscanning of the lungs, spirometry, analysis of arterial blood gases, computed tomography of the thorax and external stimulation of the phrenic nerve were performed. The measurement of transdiaphragmatic pressure was crucial to establish and confirm the diagnosis of BDP, as only a small difference in gastric and oesophageal pressures during tidal breathing and inspiratory efforts was recorded. As no cause of diaphragmatic paresis was found, the case was classified as idiopathic. The final diagnosis of non-trauma related bilateral diaphragmatic weakness was generally delayed. In the case of the described patient, dyspnoea, the main symptom he was suffering from, was supposed to result from his congenital heart defect. We recommend that the suspicion of idiopathic diaphragmatic paresis should always be raised in patients suffering from respiratory failure of unknown origin. It is, however, necessary to perform extensive diagnostics to exclude the other causes of phrenic-diaphragmatic impairment. It's also necessary to consider all infections, injuries and surgical procedures within the thorax as possible causes of diaphragmatic paresis.

Diagnosis, Differential↗
PubMed1975

[Effect of propranolol on hemodynamic shifts and respiration during physical exertion in patients with hypertensive disease].

An examination of 25 patients with hypertensive disease of the I-II stage proved that following propranolol treatment the systolic and mean arterial pressure, the rate of cardiac contractions and the minute blood volume accrue on physical effort to a lesser extent, and the circulation time, diastolic pressure and peripheral resistance ot the blood flow-to the same degree as before the medication. Changes in the phasic structure of the left ventricle of the heart in physical exertion are less marked than they were prior to the treatment. Propranolol does not materially change the level of the oxygen consumption on effort; the lactic acid level and the ratio lactate/pyruvate in the blood rise against the background of the medication with this drug to a some-what lesser degree than before the treatment.

Blood Pressure↗
PubMed2001

Mechanomyography, electromyography, heart rate, and ratings of perceived exertion during incremental cycle ergometry.

BACKGROUND: The purpose of this investigation was to examine the relationships of mchanomyography (MMG), electromyography (EMG), heart rate (HR), and ratings of perceived exertion (RPE) versus power output during incremental cycle ergometry. METHODS: Nine adult males [mean (+/-SD) age 23 (+/-3) years] volunteered to perform an incremental test to exhaustion on a cycle ergometer. The MMG, EMG, HR, and RPE values were recorded at the end of each power output. RESULTS: The normalized (expressed as a percentage of maximal values) relationships for MMG, HR, and RPE versus power output were linear, while the EMG versus power output relationship was quadratic. Furthermore, there were no significant (p > 0.10) differences between slope coefficients for the relationships among MMG, HR, and RPE versus power output. CONCLUSIONS: The results of this investigation indicated that there were close associations among the mechanical (MMG), cardiac (HR), and perception of effort (RPE) aspects of cycle ergometry. In addition, there was a dissociation between the linear MMG pattern and quadratic EMG pattern with increasing power outputs.

Adult↗
PubMed2000

Ventilatory response to exercise and rating of perceived exertion in two pediatric age groups.

The aim of this paper is to study the differences in ventilatory response to exercise in prepubertal and pubertal children. One hundred children in the following groups: 10-year-olds (25 boys/25 girls) and 13-year-olds (25 boys/25 girls) performed sub maximal treadmill stress test, using modified Balke protocol. All of them went through complex pulmonary function testing and complete anthropometrics measurements, including skinfold thickness. The relative oxygen consumption for the whole group is 38.5 +/- 4.5 mL/min/kg (mean +/- SD). The girls had higher percent fat than boys in both groups (24% vs. 16% in the first group and 27% vs. 18% in the second). With age VO2peak grows parallel with minute ventilation, tidal volume and a tendency towards lowering the breathing frequency is observed irrespective of the sex. We found significant sex differences in ventilatory equivalents for oxygen and carbon dioxide in the second group. VE/VCO2 for the boys decreased from 30.6 +/- 3.1 to 27.6 +/- 2.9; p = 0.002, but remains unchanged in girls. Another interesting fact is that older children rated perceived exertion significantly higher (Borg score 4.6 +/- 0.9 vs. 5.5 +/- 1.4; p < 0.05) despite the standard load. In conclusion there are age and sex differences in some aspects of ventilatory response in pediatric age group.

Adolescent↗
PubMedDate not supplied

[Effects of systemic hemodynamics on stimulating peripheral vascular insufficiency in young and middle-aged patients with stable exertional angina].

Identified with the aid of the rheopletismography technique was inadequate increment of blood central volume (BCV) in 55 percent out of 20 young and middle-aged patients with stable exercise-induced angina immediately after decompression of the extremities, with 20 percent of these having shown an association between significant augmentation of BCV and decrease in the velocity of bloodflow. The outlined changes in systemic hemodynamics can be regarded as criteria for dysadaptation of the cardiovascular system in young and middle-aged patients with stable exertional angina to the limb compression-decompression test.

Adaptation, Physiological↗
PubMed2001

Heart rate and ratings of perceived exertion at the physical working capacity at the heart rate threshold.

The purpose of this investigation was to examine the heart rate (HR) responses and ratings of perceived exertion (RPE) during continuous work bouts at 80, 100, and 120% of the physical working capacity at the heart rate threshold (PWCHRT). Ten men (mean age +/- SD = 23.3 +/- 2.9 years) performed a maximal cycle ergometer test and four, 8-minute submaximal work bouts for the determination of PWCHRT. Each subject then performed 3 continuous 1-hour work bouts at 80, 100, and 120% of the power output corresponding to PWCHRT. The results of the 1-hour work bouts showed that slope coefficients for the mean HR vs. time relationships for all 3 power outputs were significantly (p < 0.05) greater than zero and 0.1 bpm x min(-1). In addition, the slope coefficients for mean RPE vs. time relationships for all 3 power outputs were significantly (p < 0.05) greater than zero. The mean slope coefficients for the HR and RPE vs. time relationships indicated that the PWCHRT test overestimated the maximal power output associated with steady-state HR and RPE responses. The mean HR slope coefficient suggested, however, that the PWCHRT could be maintained for over 4 hours.

Adult↗
PubMed2001

Preferred exertion across three common modes of exercise training.

The use of self-selected intensities of exercise may increase adherence to exercise programs by allowing the participant more freedom to choose activities that are enjoyable. However, self-selected intensities may vary across exercise modes, and participants may not choose an intensity that is adequate to produce health benefits. The purpose of this study was to determine influence of exercise mode on self-selected exercise intensities. Eighteen subjects (12 men and 6 women) between the ages of 18 and 25 participated in this study. Preferred intensity tests were performed for 3 modes of exercise (treadmill, cycle ergometer, and stairstepper). .V(O)(2) values were obtained continuously and 1-minute averages were recorded at minutes 5, 10, 15, and 20 for each submaximal test. Comparisons were made using a repeated-measures analysis of variance (mode, time, mode x time). Scheffe's F test was used to test simple effects. There was a significant increase in the relative .V(O)(2) for all 3 modes of exercise across the 20-minute trials (p = 0.0001). Relative .V(O)(2) (%.V(O)(2)peak) increased from 52.20 to 64.71% for cycle exercise, 43.27 to 63.25% for the treadmill, and 47.16 to 61.17% for stairstepping. The average relative .V(O)(2) for the cycle ergometer (60.40 +/- 15.55%) was significantly higher (p = 0.02) than both the treadmill (53.65 +/- 18.36%) and stairstepper (54.66 +/- 11.98%). Relative heart rate (HR) (%HRR) for the stairstepper (80.21 +/- 9.67%) and the cycle ergometer (80.03 +/- 10.59%) were significantly higher than the treadmill (74.77 +/- 13.13%) (p = 0.0003). There were no significant differences in rating of perceived exertion (RPE) among the 3 modes of exercise. Similar RPE values were reported for the stairstepper (12.79 +/- 2.97), cycle ergometer (12.57 +/- 2.90), and the treadmill (12.50 +/- 2.87). The results indicate that subjects allowed to choose exercise intensity by self-selection chose work rates that were within the moderate range of American College of Sports Medicine guidelines of 50-85% .V(O)(2)max for treadmill, cycle ergometer, and stairstepping exercise.

Adolescent↗
PubMed1975

[Effect of anemia on various reactions of the domestic swine due to physical exertion. 2. Components of cardiovascular function and body temperature].

The following measurements were made in six anaemic and six healthy pigs during and after physical exertion on a belt moving at 70 m/min for 10 minutes at environmental temperature of 22-24 degrees C and relative humidity of 55-65%:--rectal temperature (RT), heart rate, total haemoglobin, plasma volume (PV), blood volume (BV) and plasma osmolarity (PO). The increase: in RT and PO, heart rate during exercise, respiratory rate after exercise, and the fall in PV and BV during exercise as well as changes in erythrocytes were all more pronounced in anaemic pigs than in healthy pigs.

Anemia↗
PubMed1975

[Effect of anemia on various reactions of domestic swine due to physical exertion. 4. Changes of serum acid-base equilibrium].

Carbon dioxide tension, pH and the excess of base were determined in blood samples obtained from the posterior vena cava of six healthy and six anaemic pigs subjected to ten minutes of exercise on a belt moving at 78 m/min at 22-24 degrees C and relative humidity of 55-65%. The fall in these values during physical exertion was greater in anaemic than in healthy pigs. The roles of buffering capacity and rise in body temperature, and the relationship between blood lactic acid and base excess were discussed.

Acid-Base Equilibrium↗
PubMed1975

[Lactic acid content of blood plasma in domestic swine of various breeds during physical exertion].

Lactic acid was determined by an enzymic method in plasma samples taken from 20 pigs of the German Edelschwein, German Landrace, German Saddleback and Edelschwein/Landrace crosses before, during and after being made to run on a band moving at 1.3 metres/second for ten minutes, at 10 degrees C and relative humidity of 65-75%. A special method was used to assess the degree of exertion. The lactic acid curve showed that Edelschwein and German Saddlebacks had a low regulatory capacity while German Landrace and the crossbred pigs had a large capacity. For assessing differences attributable to individuals or to breeds, the occurrence of the maximum lactic acid concentration during or after exercise was of special significance.

Animals↗
PubMed2001

Aerobic capacity & perceived exertion after practice of Hatha yogic exercises.

BACKGROUND & OBJECTIVES: Reports on the effect of yogic exercises on aerobic capacity are few. There is also no literature available on the effect of yogic exercise on perceived exertion (PE) after maximal exercise. In this study the effect of training in Hatha yogic exercises on aerobic capacity and PE after maximal exercise was observed. METHODS: Forty men from the Indian army (aged 19-23 yr) were administered maximal exercise on a bicycle ergometer in a graded work load protocol. The oxygen consumption, carbon dioxide output, pulmonary ventilation, respiratory rate, heart rate (HR) etc., at maximal exercise and PE score immediately thereafter were recorded. The subjects were divided into two equal groups. Twelve subjects dropped out during the course of study. One group (yoga, n = 17) practiced Hatha yogic exercises for 1 h every morning (6 days in a week) for six months. The other group (PT, n = 11) underwent conventional physical exercise training during the same period. Both groups participated daily in different games for 1 h in the afternoon. In the 7th month, tests for maximal oxygen consumption (VO2Max) and PE were repeated on both groups of subjects. RESULTS: Absolute value of VO2Max increased significantly (P < 0.05) in the yoga group after 6 months of training. The PE score after maximal exercise decreased significantly (P < 0.001) in the yoga group after 6 months but the PT group showed no change. INTERPRETATION & CONCLUSION: The practice of Hatha yogic exercises along with games helps to improve aerobic capacity like the practice of conventional exercises (PT) along with games. The yoga group performed better than the PT group in terms of lower PE after exhaustive exercise.

Adult↗