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[Plant scale optimization of the oxygen content of distilled water for injection].

Before dissolving oxygen sensible drugs, water for injection is boiled and flowed through with nitrogen gas in order to reduce the amount of dissolved oxygen. The aim was to optimize the amount of oxygen of water for injection in manufacturing vessel for production. A 2(2)-1 type fractional factorial design was selected to study the parameters which can influence the amount of oxygen in water for injection. The following parametes were studied: gas pressure of nitrogen (X1), flowing time of nitrogen gas (X2), boiling time of water (X3) and amount of water (X4). Performing the factorial studies the coefficients were calculated and controlled by mathematical-statistical methods. Knowing the coefficients the factorial area was left the optimum was found by Box--Wilson method.

Hot Temperature↗

Health implications of petroleum distillate ingestion.

The authors discuss the clinical approach to the management of hydrocarbon ingestions, including the role, implementation, and type of gastric decontamination utilized; the extent of medical evaluation, observation or hospitalization required; and the appropriate therapy for hydrocarbon pneumonitis. An appendix covers myocardial sensitization following inhalation abuse of hydrocarbons.

Adrenal Cortex Hormones↗

Distillation.

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Arthritis, Juvenile↗

Critical point drying by use of distilled CO2.

For avoiding specimen contamination with particles or liquid residues from CO2-supply cylinders during critical point drying the carbon dioxide is taken from the gaseous phase. Condensation takes place in the water cooled pipe between supply cylinder and CPD-apparatus. A sufficient flow of liquid CO2 is guaranteed, all solid and nonvolatile liquid contaminations are eliminated.

Animals↗