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At least 991 records · Page 55Linked to original sources
PubMed2003

[Non-tubercular vertebral osteomyelitis: diagnosis and therapy of 45 patients from a single Italian centre].

AIM OF THE STUDY: to evaluate the episodes of non-tubercular spondylodiskitis diagnosed between 1998 and 2002 at the Ospedale S. Corona, Pietra Ligure (SV). METHODS: perspective evaluation of vertebral osteomyelitis classified as spontaneous or iatrogenic if associated with procedures on the spinal cord, with detection of associated risk factors, localization, aetiology and treatment. RESULTS: 45 episodes, 71% spontaneous and 29% iatrogenic were observed. Associated risk factors were present in 47% of spontaneous spondylodiskitis. Lumbosacral localization was detected in 68% of spontaneous and 100% of iatrogenic episodes. Other localizations in spontaneous spondylodiskitis were dorsal (25%) or cervical (7%). Methicillin-sensitive staphylococci caused the majority of spontaneous spondylodiskitis, while methicillin-resistant strains were more frequently involved in iatrogenic episodes. Among spontaneous spondylodiskitis, 63% healed with antibiotics for 8 weeks, but surgery was often needed in dorsal localizations. In iatrogenic forms antibacterial therapy for 8 weeks-6 months was effective in cases not associated with foreign bodies but their presence always required surgery for healing. CONCLUSIONS: spondylodiskitis is more frequently localized at lumbosacral level. Beta-lactams are generally effective in spontaneous episodes, while iatrogenic ones often require associations of drugs. Surgery may be required in the case of dorsal localization or in the presence of foreign bodies.

Adult↗
PubMed2004

Iatrogenic spondylodiscitis. Case report and review of literature.

Iatrogenic intervertebral disc space infection is encountered following microsurgical discectomy, percutaneous laser disc decompression, automated percutaneous lumbar nucleotomy operations, and discography. The purpose of this paper is to present a case report and review the literature on the uncommon origins of pyogenic spondylodiscitis and to emphasize the significance of prophylactic antibiotic therapy following transrectal ultrasonography-guided needle biopsy of the prostate (TUGNBP). According to the authors, this is the first reported case of pyogenic spondylodiscitis as a complication of TUGNBP in the English language literature.

Biopsy, Needle↗
PubMed2004

Viridans streptococcus endocarditis associated with spondylodiscitis.

The authors report a case of a 78-year-old male, admitted to the Hospital with fever, lumbar pain and a systolic murmur. Viridans streptococcus endocarditis associated with spondylodiscitis was diagnosed. Images and results of the exams are presented. This case is compared with similar studies in the literature.

Aged↗
PubMed1992

Case report of an unusual cause of low back pain. Intervertebral diskitis caused by Eikenella corrodens.

A 42-year-old man suffered from low back pain caused by intervertebral diskitis. The condition was diagnosed on plain roentgenogram and computed tomography scans. The infected area was biopsied and grew Eikenella corrodens, a gram-negative anaerobic rod, which grows slowly only after culture on blood agar in 5-10% carbon dioxide. This is the first reported case of E. corrodens intervertebral diskitis causing acute low back pain. Recognition of this organism in this condition emphasizes the importance of aerobic and anaerobic cultures of infected disks. The organism has unusual antibiotic sensitivities. The infection, once appropriately treated, responded rapidly.

Adult↗
PubMed1992

[Septic arthritis due to Streptococcus bovis].

A 47-year-old man presented with arthritis of the right shoulder and spondylodiscitis by Streptococcus bovis. This microorganism is a frequent cause of endocarditis and has been associated with gastrointestinal neoplasm, mainly carcinoma of the colon; however up to the present it had not been described as an causal agent of septic arthritis. The studies carried out on the patient permitted the exclusion of the existence of a digestive neoplasm and endocarditis. Despite a prolonged evolution prior to treatment with elevated doses of penicillin G and not requiring surgical drainage, the evolution was good and no destructive lesions were produced in the shoulder joint. Hematogenous infections (in this case septic arthritis) by Streptococcus bovis may present in patients without gastrointestinal diseases or endocarditis, possibly have a low damage to skeletal structures and respond adequately to conventional treatment with penicillin G.

Arthritis, Infectious↗
PubMed2004

[Spondylodiscitis caused by a strain of Staphylococcus aureus, in vitro sensitive to penicillin].

The case history of a man referred to our department with the diagnosis of purulent meningitis; actually, he presented spondylodiscitis of the lumbar spine with the infection spreading into the spinal canal and the left psoas muscle. The disease was caused by a strain of Staphylococcus aureus, which in vitro was sensitive to penicillin. However, treatment with crystalline penicillin in combination with ciprofloxacin failed. The paper suggests a differential diagnosis permitting to distinguish a typical purulent meningitis and an abscess in the spinal canal. The authors also discuss the suitability of administering penicillin in staphylococcal sepsis caused by a sensitive strain. The authors do not recommend crystalline penicillin in the management of severe staphylococcal infections even in cases, where the isolated S. aureus strain is really sensitive to penicillin.

Discitis↗
PubMed1992

Disseminated aspergillosis in a dog with diskospondylitis and neurologic deficits.

A German shepherd dog was treated initially for signs of urinary tract infection; subsequently, signs of spinal pain and neurologic deficits developed. Fungal hyphae were found in the urine sediment, and spinal radiography revealed changes in the vertebrae and intervertebral disks at the levels of T3 to T8, T12 to T13, L3-4, and L5-6, consistent with diskospondylitis. Fungal cultures of urine and specimens from spinal lesions yielded Aspergillus terreus. Itraconazole (5 mg/kg of body weight, PO, q 24 h) was used to treat this infection, and locomotion improved. Sudden death occurred 4 weeks after treatment was initiated; this was attributed to exsanguination associated with a weakened renal artery. This dog was raised in Florida and resided in central Virginia. The disseminated aspergillosis found in this dog was not limited to the hot arid climates that some reports suggest are optimal conditions for growth.

Animals↗
PubMed2004

Juvenile spondylodiscitis: the value of magnetic resonance imaging: a report of two cases.

Two boys presenting with reluctance to sit straight and stand were diagnosed with spondylodiscitis of the lumbar spine. After confirmation of the diagnosis on plain radiographs, computed tomography and magnetic resonance imaging, they were successfully treated with antibiotics and in one case a lumbar orthosis. The use of magnetic resonance imaging is discussed and compared to the other radiological techniques. Magnetic resonance imaging seems to be the most sensitive and specific imaging technique used in the diagnostic process of spondylodiscitis. Computed tomography and technetium bone scan both play a specific part in the process of diagnosis and follow-up.

Anti-Bacterial Agents↗
PubMed1992

[Tuberculous pre- and paravertebral abscess with spondylodiscitis].

A rare case of an adult with a large retropharyngeal cold abscess arising from a lesion of the upper cervical spine and causing airway obstruction is presented. The incidence, clinical features, and early diagnosis of spondylitis by magnetic resonance tomography, and the management of a retropharyngeal abscess are discussed.

Abscess↗
PubMed2005

[Infectious complications after epidural analgesia to control pain after abdominal surgery].

Epidural abscess as a complication of spinal analgesia is rare, but because of its potential clinical implications it must always be watched for in patients who have undergone epidural procedures. The case we report is of interest because of the long latency period between removal of the catheter and the onset of clinical signs and because of the rarity of the pathogen implicated in forming the abscess (Candida albicans).

Ampulla of Vater↗