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[In vivo densitometry of the skeleton by single energy CT body scanner for clinical use. Technical procedure. Cross-sectional study of 124 subjects on the role of age and sex. Evaluation of the cortical/spongiosa ratio as a function of age].

CT 5005 EMI Scanner 140 kVp. Abstraction of the HN in the cortical of the right femural diaphysis and in the spongiosa of the vertebral body (L1). 124 clinically normal subjects of both sexes (63 males and 61 females), aged between 20 and 87 years were grouped into 7 categories according to age decade. Cortical-male - The variations of bone mineral content are not correlated either with age or with sex. Cortical-female - Modest correlation with age but not calculable with sex. Spongiosa-male - Excellent correlation with age (r = --0,975; (p less than 0,005). In each decade the average male values are superior to the female values. Spongiosa-female - Excellent linear correlation with age (r = --0,945; p less than 0,005). The average values for each decade are inferior to those of the males. The cortical/spongiosa ratio increases in relation to age: in males (r = --0,896; p less than 0,01) and in females (r = --0,885; p less than 0,01). The bone mineral content loss in the IX decade compared to the III decade is equal in males and in females in both the cortical (--20%) and the spongiosa (--65%). The reduction curves with the CT body scanner are not comparable to those obtained with other techniques. They result as being compatible with those obtained through histomorphometry (trabecular bone density).

Adult↗
PubMed1983

Foveal densitometry in retinitis pigmentosa.

Cone density and psychophysical thresholds were investigated in patients with retinitis pigmentosa. Our aim was to assess possible disturbances of foveal cones, especially in patients with good visual acuity. Using the continuously recording densitometer described by van Norren and van der Kraats, we examined ten patients (19 eyes). With the same apparatus it was possible to determine cone final threshold. In all patients double density values were lower than in an age-matched and sex-matched control group of an equal number, and the half time of regeneration was increased in eight eyes. In 12 eyes of eight patients the foveal final threshold was raised above normal. Pseudoprotanomaly was found in seven eyes in four males. Possible explanations for these findings are discussed. Since reduced double density was found in all patients with retinitis pigmentosa, we conclude that disturbed foveal cones are probably a common and rather early feature in this disease.

Adult↗