Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Computer Systems”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 991 records · Page 55Linked to original sources
PubMedDate not supplied

From a theoretical framework of human exposure and dose assessment to computational system implementation: the Modeling ENvironment for TOtal Risk Studies (MENTOR).

Georgopoulos and Lioy (1994) presented a theoretical framework for exposure analysis, incorporating multiple levels of empirical and mechanistic information while characterizing/reducing uncertainties. The present review summarizes efforts towards implementing that framework, through the development of a mechanistic source-to-dose Modeling ENvironment for TOtal Risks studies (MENTOR), a computational toolbox that provides various modeling and data analysis tools to facilitate assessment of cumulative and aggregate (multipathway) exposures to contaminant mixtures. MENTOR adopts a "Person Oriented Modeling" (POM) approach that can be applied to either specific individuals or to populations/subpopulations of interest; the latter is accomplished by defining samples of "virtual" individuals that statistically reproduce the physiological, demographic, etc., attributes of the populations studied. MENTOR implementations currently incorporate and expand USEPA's SHEDS (Stochastic Human Exposure and Dose Simulation) approach and consider multiple exposure routes (inhalation, food, drinking water intake; non-dietary ingestion; dermal absorption). Typically, simulations involve: (1) characterizing background levels of contaminants by combining model predictions and measurement studies; (2) characterizing multimedia levels and temporal profiles of contaminants in various residential and occupational microenvironments; (3) selecting sample populations that statistically reproduce essential demographics (age, gender, race, occupation, education) of relevant population units (e.g., census tracts); (4) developing activity event sequences for each member of the sample by matching attributes to entries of USEPA's Consolidated Human Activity Database (CHAD); (5) calculating intake rates for the sample population members, reflecting physiological attributes and activities pursued; (6) combining intake rates from multiple routes to assess exposures; (7) estimating target tissue doses with physiologically based dosimetry/toxicokinetic modeling.

Complex Mixtures↗
PubMedDate not supplied

[Conception and implementation of the federal computer system for families with hereditary diseases].

The Federal Genetic Register (FGR) is a multi-functional system. It will be realized in a form of a corporative network. The main goals of FGR are prophylactic medical examinations, support of a doctor's decision about a genetic risk in families with inherited diseases, monitoring of congenital anomalies and hereditary diseases, supply of data. The system is created using Microsoft Visual FoxPro 3.0 and Visual C++2.1. The operating system Windows NT will conform to that of interregional centers/consultation and Windows for Workgroup 3.11 or Windows'95 will conform to that of regional consultation.

Adult↗
PubMed1982

[An interactive computer system for control, handling and recording of vestibular tests].

One processor controls and records the standard leakage of spontaneous nystagmus and the rotatory and caloric tests in three laboratories. It cyclicly scans the horizontal and vertical electronystagmographic leakage from all rooms and it stores the results of its measurement on to a magnetic disk. If these data are to be archived, the computer first calls for the patients's records and then it transfers the test data from the magnetic disk on to an analogous magnetic tape with a tenfold reduction of the time interval. A 3,600-feet-long magnetic tape contains the results of test measurements for a total of 256 h, corresponding to 800-1,000 vestibular tests. With the computer, it is possible to introduce modifications of all vestibular tests, to stop a test at any time, or to plot an electronystagmogram on a curve tracer.

Computers↗
PubMed2002

A computer system for acoustic analysis of pathological voices and laryngeal diseases screening.

A system for acoustic analysis of pathological voices is proposed. The vocalized part of the voice signal is separated and all glottal cycles are traced by means of a cross-correlation detector. Based on the so determined beginning and duration of all glottal cycles, shimmer, jitter, several harmonics-to-noise ratios and other widely used acoustic parameters are calculated. New parameters are also introduced for estimation of the turbulent noise in voice signals (Turbulent Noise Index - TNI) and for the "breathy" voice characterization (Normalized First Harmonic Energy - NFHE). These parameters are applied for laryngeal pathology detection. An identification accuracy of 96.1% by the K-nearest neighbors' method has been achieved. The system is clinically tested.

Algorithms↗
PubMed1995

[Evaluation of a computer system by nursing students].

This study was undertaken to investigate the opinion of nursing undergraduate students of the first year about the discipline "Informatic applied to health". Data were collected using a questionnaire with open and closed questions applied through three consecutive years (1989, 1990, 1991). The results showed that undergraduate students considered this course important. Student's expectations were related to the necessity to get familiar with computers. The mentioned critiques were related to the necessity of more time and equipments to support a better learning process.

Attitude to Computers↗
PubMed1982

Managing computer systems. Developing the proposal.

The major components of a thorough proposal to computerize pharmaceutical services are described. The components of the proposal are (1) the introduction; (2) description of current and proposed systems; (3) hardware, software, and supplies; (4) vendor selection; (5) implementation; (6) interface; (7) justification of need; (8) risk analysis; (9) contract; (10) summary; and (11) appendices. Special emphasis is given to justifying the pharmacy system on the basis of decreased cost for personnel, drugs, charging for services, and equipment. Additional justification is based on the benefits of increased production, decreased problems, and increased capacity to produce. A life-cycle cost analysis and engineering economy formula is described that can be used to calculate the number of full-time equivalents that must be reduced in order to offset costs of the system through personnel reduction alone. Because the decision to computerize pharmaceutical services constitutes a major and permanent change, it is important that the proposal be logical, factual, thorough, and organized.

Computers↗
PubMed1983

A computer system for real-time data acquisition and analysis of biopotentials and quantal content at the neuromuscular junction.

A computerized data acquisition system for on-line analysis of the parameters of neuromuscular transmission is described. Both hardware usage and software methodologies are discussed with regard to sampling in real-time and analyzing miniature end-plate potentials (MEPPs), end-plate potentials (EPPs) and quantal content of the evoked transmitter release. Significant features of the program include: (1) automatic threshold determination for MEPP detection; (2) the use of a circular buffer to give pre-trigger information; (3) real-time noise spike rejection; (4) an automatic procedure for EPP failure detection; (5) rapid quantal content determinations by several methods as well as complete MEPP and EPP waveform analysis. The system has proven both accurate and reliable during more than two years of use. Advantages of the system over conventional methods include: (1) increased accuracy and efficiency in data analysis; (2) immediate availability of results; (3) conventional data storage; (4) flexibility to meet changing requirements.

Action Potentials↗
PubMedDate not supplied

[Analog gamma camera digitalization computer system].

OBJECTIVE: Digitalization of analogue gamma cameras systems, using special acquisition boards in microcomputers and appropriate software for acquisition and processing of nuclear medicine images is described in detail. MATERIAL AND METHODS: Microcomputer integrated systems interconnected by means of a Local Area Network (LAN) and connected to several gamma cameras have been implemented using specialized acquisition boards. The PIP software (Portable Image Processing) was installed on each microcomputer to acquire and preprocess the nuclear medicine images. A specialized image processing software has been designed and developed for these purposes. This software allows processing of each nuclear medicine exam, in a semiautomatic procedure, and recording of the results on radiological films. RESULTS: . A stable, flexible and inexpensive system which makes it possible to digitize, visualize, process, and print nuclear medicine images obtained from analogue gamma cameras was implemented in the Nuclear Medicine Division. Such a system yields higher quality images than those obtained with analogue cameras while keeping operating costs considerably lower (filming: 24.6%, fixing 48.2% and developing 26%.) CONCLUSIONS: Analogue gamma camera systems can be digitalized economically. This system makes it possible to obtain optimal clinical quality nuclear medicine images, to increase the acquisition and processing efficiency, and to reduce the steps involved in each exam.

Computers↗
PubMed1979

Comparison of admission criteria and medical school progress: preliminary results from a simple computer system.

The MFSEL system is designed to collect the data on entrants to the Glasgow medical course that was available to the Admissions Committee at the time of selection, and compare it with performance in medical school (and possibly later). The data collection has been made by the Admission Committee's secretary and the programming by a medical member with little previous experience and a minimum of professional help. Computing and data preparation costs have been low. Preliminary analyses indicate that selection has not been biased by the sex, class, or medical parenthood of entrants, and that the Scottish Sixth Year Studies examinations are a reliable predictor for student performance.

Adolescent↗
PubMed2001

A telephone-linked computer system for COPD care.

The current revolution in communications technology provides an opportunity for novel approaches to management of medical illness. As economic imperatives lead to a progressive reduction in the time that health-care providers spend with their patients, computerized, telephone-linked communication systems offer an inexpensive, widely available alternative with which patients and providers can maintain contact. Such systems may be particularly useful for providing ongoing monitoring and education of patients with chronic illnesses such as COPD. In this article, we describe the general application of telephone-linked communication systems in the health-care setting. We then present in detail one such system, which provides telephone-linked care for COPD (TLC-COPD). The operation of the system is described, as are its theoretical underpinnings in social learning theory. A randomized clinical trial currently is being performed to study the effects of the TLC-COPD system. The rationale for expected improvements in disease control and quality of life, and for a reduction in acute health-care utilization, is discussed.

Algorithms↗
PubMed1994

[Computer system of electronystagmographic examination. Part II. Analysis of nystagmus].

It is a description of automatic registration and analysing of the eyes movement. In this method had beed applied a test of the eye movement in the limited momentary speed, test of the time taken by the deflection and the test of unanimity in analysing both deflection and direction of the quick phase. The analysis procedure has two stages. In the first stage the signal undergoes an introductory analysis which is aimed at smoothing it out and approximating it a saw-toothed shape. At this stage the computer identifies the phases, direction of nystagmus and deflection which are not real eye deflections. In the second stage the computer makes measurements of nystagmus parameters.

Caloric Tests↗