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[Vaginalcytology and late pregnancy (determination of term, fetal monitoring, correlation with hormon patterns) (author's transl)].

The "before term" pattern allows to exclude over-maturity with probability of 95--100%. The "at term" pattern lets expect spontaneous labour in next five days just so with great probability. We attribute no importance to cytology as a method of control for high risk pregnancies. At last we didn't find any correlation with statistical methods between the alterations of the cell patterns some days before delivery and values of hormons.

Female↗

The etiology of preeclampsia: a hypothesis.

Recent investigations into the pathophysiology and immunobiology of preeclampsia have strongly implicated immunologic dysfunction as a central feature of this disease. A hypothesis is herein presented which unifies current research with clinical manifestations, in an attempt to clarify the etiology of this obstetric enigma.

Female↗

[Investigations regarding the validity of estrogen-creatine quotients from morning urine compared with those from 24-hour urine in high risk pregnancies (author's transl)].

An automated method for determining total estrogen in 24-hour urine was reported. The "estrogen-creatinine quotient" was computed in order to make the results of collective errors as independent as possible. This numerical value also makes possible comparative studies of 24-hour urine and morning urine (6:00 a.m.) as well as of urine specimens taken every two hours between 6:00 a.m. and 6:00 p.m. A total of 1000 analyses were made in 110 pregnant women; in addition, 82 daily profiles were studied. A high correlation was found between the E/C from 24-hour urine and from morning urine. In approximately two thirds of the cases, the deviation between morning urine and 24-hour urine did not exceed 10%. In the daily profiles, however, a wide variation in the daily rhythmn of some patients could be observed. According to our results, the determination of E/C in morning urine is well suited as a screening method for quick detection of estrogen elimination, particularly in high risk pregnancies.

Circadian Rhythm↗

[Significance of urinary tract infections in gynecologic diseases and in pregnancy].

In search of urinary tract infections 3185 gynaecological patients and 1600 pregnant women were examined by means of TTC-Test. 12.8% of the gynaecological patients and 12% of the pregnant women showed bacteruria. A special disposition to urinary tract infection was found by patients suffering from descensus, fistula of urogenital system and by gravid women with toxaemea of pregnancy and diabetes mellitus. Infection through E. coli was found to be dominating and the germs showed a relatively high sensitivity against Chloramphenicol and Nifurantin now as before. Problems of diagnosis and therapy are discussed. The necessity of most effective screening methods, of early diagnosis and of interdisciplinary team-work is pointed out.

Adult↗

Incidence and forms of EPH gestosis in twin pregnancy.

An increased incidence of EPH gestosis in twin pregnancies is frequently reported. During the past 12 years, 188 women gave birth to twins in our hospital. For these mothers, the incidence of EPH gestosis on admission was 42.5%, in contrast to 31.4% for a control group matched for age, parity and nationality. EPH gestosis occurring in twin pregnancies was more severe than that in single pregnancies.

Female↗

Midtrimester preeclamptic toxemia in triploid pregnancies.

Nineteen advanced triploid pregnancies reported in the literature are reviewed. In 8 of 14 pregnancies for which reliable data were available, severe preeclamptic toxemia (EPH gestosis) developed, most often from the 16th to the 24th week of gestation. In all the toxemic cases, the placenta was large for the stage of pregnancy, the placental coefficient was high (mean 0.83) and extensive areas of molar degeneration were present. Advanced triploid pregnancy is considered a further example of hyperplacentosis causing preeclamptic toxemia. The study of toxemic and nontoxemic advanced triploid pregnancies supports the assumption that hyperplacentosis, rather than being related to excessive placental size, is the expression of trophoblastic hyperactivity.

Adult↗

EPH gestosis in Glasgow, 1970.

Perinatal deaths due to EPH gestosis which occurred in Glasgow during 1970 were studied. There was a high frequency of perinatal deaths among babies born to primigravidae below the age of 20 years and to mothers with proteinuria. The majority of the deaths occurred in babies weighing less than or equal to 2,500 g. It is suggested that some of the deaths were avoidable and that a further reduction in perinatal mortality can still be achieved.

Adult↗