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At least 973 records · Page 54Linked to original sources
PubMed1989

Studies of human leprosy lesions in situ using suction-induced blisters. 1. Cellular components of new, uncomplicated lesions.

The cellular contents of blisters induced by suction over new, uncomplicated leprosy lesions, and in the skin of cured, control patients, have been examined with enzyme- and immuno-histochemical staining over a period of 4 days. The total cellularity of the blisters varied over a wide range, not correlated with the type of leprosy. Mononuclear cells predominated at all times studied, with nearly equal percentages of monocytes and T lymphocytes. The T-helper: suppressor ratio was significantly greater in BT than in BL and LL lesions at 48 hr. Suction blisters offer a painless, quantitative, reproducible, multiple-sampling method for obtaining cells from the cutaneous infiltrates of leprosy for phenotyping or functional analysis.

Blister↗
PubMed1989

A national survey of complications associated with suction lipectomy: a comparative study.

In March of 1988, a survey form was sent to all 2695 U.S. and Canadian members of the American Society of Plastic and Reconstructive Surgeons. Nine-hundred and thirty-five members responded, for a response rate of 34.7 percent. The purpose of the survey was to ascertain the total number of major liposuction, dermatolipectomy, and abdominoplasty procedures performed from January of 1984 to January of 1988 and to compare nine specific complications that are associated with these three procedures. The 935 surgeons reported a total of 112,756 procedures performed: major liposuction (75,591), dermatolipectomy (10,603), and abdominoplasty (26,562). Nine major complications were surveyed: mortality, myocardial infarction, cerebrovascular accident or transient ischemic attack, pulmonary thromboembolism, fat embolism, major skin loss, anesthesia complication, transfusion complications, and deep venous thrombosis. The findings in this survey showed, when comparing these three procedures and the nine types of complications, that the complication rate for major suction lipectomy was 0.1 percent, for dermatolipectomy 0.9 percent, and for abdominoplasty 2.0 percent. Fat emboli did not prove to be a significant factor associated with any of the three procedures. However, of the 15 reported deaths (major liposuction 2, dermatolipectomy 2, and abdominoplasty 11), pulmonary thromboembolism was the causative factor in 9 deaths (60 percent). Based on these analyzed data, we feel that major suction lipectomy has a low complication rate and is a reasonably safe procedure.

Abdominal Muscles↗
PubMed1989

Suction lipectomy in the management of limb lymphedema.

We have been pleased overall with the results achieved using suction lipectomy in lymphedema patients. In appropriately selected patients, it is predictable and well-tolerated. It is, however, only palliative and temporary. It may be performed on a periodic basis. Compressive stockings are essential for success. Based on our experiences, we recommend suction lipectomy for mild temporary cases, specifically involving the upper extremity, and liposuction plus excisional debulking for more severe cases and for the lower extremity.

Adolescent↗
PubMedDate not supplied

Pharmacokinetics of griseofulvin in blood and skin suction blister fluid of rats.

The penetration of griseofulvin to its site of action was investigated in the rat using subepidermal blisters induced by suction as a model. Griseofulvin was administered iv at a dose of 20 mg/kg after which blood, suction blister fluid (SBF), and skin tissue were sampled over a 300-min time period. The blood level/time course can be described by a two-compartment model. During the terminal phase, concentrations of drug in blood, SBF, and cutis declined in parallel, with respective half-lives of 71.0, 70.4, and 74.6 min. In SBF, maximum concentrations (2.35 +/- 0.36 micrograms/ml) were obtained 60 min postinjection, drug levels increased until the concentrations of unbound griseofulvin in SBF and plasma were identical. Time to peak concentration in cutis was shorter (20 min; 13.9 +/- 0.5 micrograms/ml). As the dermatophytes are located in the horny layer, the determination of griseofulvin in SBF seems to be a more suitable assay for determining the griseofulvin level profile at its site of action. In addition, the level of unbound, and thus active, griseofulvin in SBF was severalfold lower than the concentration of total drug in excised skin tissue. Up to now, the latter value has been considered to indicate that the concentration of griseofulvin in the skin is comparable to the in vitro sensitivity of dermatophytes. The present results show that this seems to be no longer justified.

Albumins↗
PubMed1978

[Physical forces in blister formation. II. Examination of total osmolality in blister fluid of suction blisters, "naturally" developed blisters and in serum (author's transl)].

Total osmotic pressure does not differ significantly in suction blister fluid or in serum of healthy persons from blister fluid, suction blister fluid or serum of patients with dermatitis herpetiformis, bullous contact dermatitis and pemphigus vulgaris. The average values reach about 293 mOsmol/kg. This results from direct measurement of total osmolality with an electronic semimicroosmometer based on the principle of freezing point reduction. In opposite to colloid osmotic pressure the total osmotic pressure does not take part in blister formation of human skin in spite of the different concentrations of the single electrolytes in the fluids of various blisters.

Blister↗
PubMed1979

Management of the perineal wound with constant irrigation and suction after abdominoperineal excision for cancer of the rectum. A new suction/irrigation drain.

The technique of primary closure of the perineal wound combined with continuous irrigation and suction of the operative site has been used in 21 patients who underwent abdominoperineal excision for cancer of the rectum or anal canal. Primary healing occurred in 19 patients within 18 days, and all patients healed within 2 months. These results are in marked contrast to those in 38 patients treated with constant suction alone, of whom only 17 healed primarily.

Anus Neoplasms↗
PubMed1981

Dissociation of suction blister roof epidermis with trypsin and desoxyribonuclease into viable single cells.

Human epidermis, obtained in vivo by the suction blister method, was dissociated with trypsin and desoxyribonuclease into a single-cell suspension. Autoradiographic analysis of the blister roof epidermis and of the epidermal cell suspension was performed to show that neither the suction procedure nor the enzymatic dissociation affected DNA synthesis of the epidermal cells.

Adult↗
PubMed1984

Quantitative determination of methoxsalen in human serum, suction blister fluid and epidermis by gas chromatography mass spectrometry.

A selected ion-monitoring gas chromatographic mass spectrometric method is described for the determination of methoxsalen employing trioxsalen as internal standard. Methoxsalen in the serum and skin of 5 psoriatic patients after PUVA bath therapy was determined. Quantitative gas chromatographic mass spectrometric analysis was performed in the election impact mode by monitoring the ratio of ions m/z 216/228. The methoxsalen level in human serum varied between 3-15 ng/ml, in suction blister fluid between 2-9 ng/ml and in suction blister roof (epidermis) between 6-242 ng/g during the first 30 min after the methoxsalen bath.

Blister↗
PubMed1983

Suction curettage.

In the decade after the legalization of elective abortion by a Supreme Court decision in January 1973, suction curettage has been widely used and accepted as a safe outpatient procedure for first-trimester abortion. Evaluation of the patient for feasibility of the procedure requires careful assessment of gestational age and the determination of the absence of an ectopic pregnancy and conditions that might contraindicate local anesthesia. Counseling clarifies the patient's options and ensures her understanding of the implications of abortion so that she can give an informed consent. Suction curettage is performed under local anesthesia using a sterile plastic cannula or curette inserted through a progressively dilated cervix with aspiration of the uterine contents by an electric pump. The procedure is completed by the physician's examination of the aspirate for the presence of placental villi. Postoperative instructions include contraception and monitoring for hemorrhage and infection prior to a return visit in 10 to 14 days. Complications can be reduced by careful selection of patients with appropriate duration of pregnancy, the use of gentle operative technique, antibiotics for prophylaxis of infection, and a continued maintenance of experience and procedural skill by the physician.

Abortion, Induced↗
PubMed1983

A study of the healing-over in the cardiac muscle using suction electrodes.

Suction electrodes were used to investigate the phenomenon of the healing-over in preparations of rabbit, cat and dog ventricular muscles. At least two processes were shown to participate in the process of the healing-over: a rapid one (time constant approximately 1 min) and a slow one (time constant approximately 10 min). Procion Yellow dye was used to determine the size of the injured zone under the suction electrode tip. Larger tips resulted in larger zones injured. The specific resistance of the border formed during the healing over was estimated to be in the range of approx. 1 k omega X cm2, i.e. much smaller than that of the intact surface membrane.

Action Potentials↗
PubMed1981

Rapid diagnosis of respiratory syncytial (RS) virus infection by immunofluorescence: a simplified procedure for the preparation of nasopharyngeal suction specimens.

A preliminary report on a simplified procedure for the preparation of nasopharyngeal suction specimens making direct smears of aspirated material is presented. The smears were examined by the indirect immunofluorescence (IF) technique for the presence of respiratory syncytial (RS) virus antigens. Specimens form 99 children with acute respiratory tract illnesses were collected during the winter season 1978-79, and RS virus was identified in samples from 45 of these patients. Serological investigations run in parallel showed fairly good correlation with the IF examinations of the smears. This simplified procedure for the preparation of nasopharyngeal suction specimens may be recommended when the conventional preparation cannot readily be performed.

Antibodies, Viral↗
PubMed1978

Suction curettage of the endometrium in an ambulatory patient.

A review is presented of patients in whom suction curettage of the endometrium was performed as an office procedure. A total of 978 curettages were performed on 943 patients. In 14 patients (1.1%) the procedure was not completed primarily because of marked cervical stenosis. Fifteen cases of adenocarcinoma of the endometrium and 28 cases of adenomatous hyperplasia and atypical adenomatous hyperplasia of the endometrium were diagnosed. The suction curettage was demonstrated to be a simple, safe, efficient and cost-saving alternative to a hospital D&C.

Adolescent↗
PubMed1977

Prostaglandin E2 in blister fluid of bullous diseases and experimental suction blisters.

Prostaglandin(PG)-like activity in the fluid of spontaneous and suction blisters was measured by bioassay on isolated guinea-pig colon after acidic lipid extraction. The fluid from spontaneous blisters in 15 patients with various bullous dermatoses, such as pemphigoid, porphyria cutanea tarda, erythema multiforme, contact dermatitis, X-ray dermatitis, all contained measurable amounts of activity, varying from 0.4 to 54 ng/ml, expressed as PGE2-activity. From 4 patients with pemphigoid, samples of fluid were collected, adequate to permit of analysis regarding the identity of the spasmogenic material. In silicic acid column chromatography, thin-layer chromatography, and in reversed phase partition chromatography, the major part of the biological activity co-chromatographed with 3H-PGE2. In one patient part of the activity coincided with PGF2alpha. The PG-like activity of experimental suction blisters was found to be significantly higher in patients with dermatitis herpetiformis than in control and psoriasis patients. The appearance of PGs in blister fluid is compatible with a role as chemical mediator involved in blister formation.

Adult↗
PubMed1980

Transient bacteremia following endotracheal suctioning in ventilated newborns.

Endotracheal suctioning is a routine procedure in ventilated newborns. A study of ten neonates demonstrates the association of transient bacteremia with endotracheal suctioning. This complication in ventilated newborns, with colonization of the respiratory tract by the same organism, must be considered in the pathogenesis of systemic infection.

Female↗
PubMed1995

[Ultrasonic suction lipectomy. A mini-invasive treatment of obesity].

The safety of ultrasounds lipolysis in the treatment of local obesity and lipodystrophies versus suction lipectomy (less blood loss because of a lower impact on blood vessels network, and less mortality) induced us to combine these mini-invasive techniques in the treatment of obese patients. Between 1991 and 1994 we treated 205 patients (146 females, 59 males, 18-59 range age), affected by 1st degree obesity (44.4%), 2nd degree obesity (27.3%) and 3rd degree obesity (28.3%), accordingly to the following schedule: 1) general anesthesia; 2) subdermal infiltration of the operating sites of a cold sodium chloride (0.9%) epinephrine solution (1:10(5), 8 degrees C); 3) 0.5 cm cutaneous incisions; 4) introduction of titanium tips as ultrasounds source; 5) insertion of suction lipectomy probes to remove the adipose tissue destroyed by ultrasounds; 6) drainage of the wide subcutaneous space; 7) setting of elastic bandages. Mortality was zero and very low side effects have been observed. We report an improvement of blood glucose and triglycerides level and blood pressure 30 days after surgery. Fair late postoperative improvement of the blood glucose tolerance test have been seen in 3 cases.

Adolescent↗
PubMed1994

Evidence of cardiac suction in the presence of high end-diastolic filling pressure: a case report.

Cardiac suction has been previously demonstrated in the normal heart and in cardiac diseases characterized by a normal or reduced end-diastolic ventricular pressure. We report a patient with tight mitral stenosis and severe tricuspid regurgitation who provides the evidence of cardiac suction, despite the presence of increased end-diastolic pressures. The negative diastolic pressures observed in our patient appear to be related to the preservation of a vigorous contraction of both ventricles resulting in small end-systolic volumes. In this setting the elastic potential energy stored in the myocardium during each vigorous contraction is released during diastole, thus creating a negative pressure which sucks blood into the ventricles.

Diastole↗
PubMed1993

Suction lipectomy: outcome relates to region-specific lipoprotein lipase activity and interval weight change.

To determine the effects of suction lipectomy on regional adipose tissue metabolism, nine women had repetitive circumferential measurements and biopsies of subcutaneous adipose tissue from a lipectomy site (site A) and a nonlipectomy site (site B) up to 12 months following lipectomy. Maximum reductions from preoperative baseline in weight, body mass index, and circumferences of sites A and B occurred at 3 months. Because of variable long-term compliance (6 to 12 months), we created a "last visit" time-point to assess adequately the effects of lipectomy for each individual. Not all subjects maintained reduction in site circumferences from 3 months to the last visit. The change in circumference of site A for that period was highly correlated with the change in circumference of site B (r = 0.828, p = 0.005). The change in circumference of site B, but not site A, at 3 months was related to the weight change above the weight of adipose tissue removed at suction lipectomy. Five subjects who were "sustained responders" to the lipectomy procedure were able to maintain or decrease circumferences of sites A and B from 3 months to the last visit. In contrast, four "limited responders" actually increased circumference of site A and had either no change or increased circumference of site B from 3 months to the last visit. The changes in circumference in both sites between 3 months and the last visit related to changes in body weight over the same interval. Ultimately, the decrement in circumference of site A was 3.4 percent (-2.4 cm) greater than that of site B (p = 0.0001). The response to lipectomy in site B, but not site A, between 3 months and the last visit was related to the change in fasting adipose tissue lipoprotein lipase from baseline to 3 months (r = 0.728, p = 0.026). This change in lipase activity in the control region may represent a metabolic defense of body weight in response to adipose tissue removal in the lipectomy site.

Abdomen↗
PubMed1996

[Intracavity suction and drainage in a patient with giant bulla accompanied by pneumoconiosis and emphysema: a case report].

A 74-year-old man with giant bulla accompanied by pneumoconiosis and emphysema was treated by intracavity suction and drainage procedure using chemical irritant and fibrin glue. About one month later, the bulla disappeared and the patient symptomatically improved on discharge from hospital. Intracavity suction and drainage is safe and effective treatment of emphysematous bulla in patients considered to be a bad risk for formal thoracotomy.

Aged↗