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At least 973 records · Page 54Linked to original sources
PubMed2005

[Spinal cord compression from a malignant pleural mesothelioma].

Thoracoscopy-talc led to the diagnosis of epithelial pleural mesothelioma in a 58-year-old man who presented with pleurisy. The course was rapidly unfavorable despite systemic chemotherapy. Dorsal pain revealed invasion of the spine and spinal canal leading to cord compression three months after the diagnosis of mesothelioma.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed2000

Spinal cord compression due to tumours at Kenyatta National Hospital, Nairobi.

OBJECTIVE: To determine the frequency of different types of tumours associated with cord compression, their mode of presentation and treatment outcome. DESIGN: Retrospective study. SETTING: Kenyatta National Hospital (KNH), a teaching and referral hospital in Nairobi, Kenya, from January 1985 to December 1994. SUBJECTS: Thirty eight patients. RESULTS: There were twenty one males and seventeen females with a male/female ratio of 1.3:1 and a mean age of 36.9 years. Primary spinal cord tumours were more common (65.8%) than metastatic tumours (34.2%). The commonest spinal cord tumour was meningioma (23.7%) followed by neurofibroma (15.8%). Most of the patients (70%) did not show any clinical improvement after surgery. CONCLUSION: Spinal cord tumours accounted for about 15% of all CNS tumours treated at the Kenyatta National Hospital. Most of the patients had total paralysis of the limbs at the time of presentation. Meningiomas and neurofibromas were the commonest cause of cord compression at KNH. Greater effort is needed to detect these tumours early when the signs and symptoms may be reversible following surgery.

Adolescent↗
PubMed1984

[Epidural angiolipoma: a rare and curable cause of spinal cord compression].

A 48-year-old female developed a slowly progressive paraparesis due to a posterior epidural mass extended on several thoracic segments. Clinical and myelographic appearance was strongly in favour of metastasis, the most common tumors in the spinal epidural space. A laminectomy was carried out and disclosed an encapsulated epidural tumor which was loosely adherent to the dura matter. Histological features were those of an angiolipoma. A brief review of clinical and pathological characteristics of spinal lipomas is performed. Extradural spinal angiolipomas are unusual benign neoplasms. The results of surgical treatment in this location are mostly excellent.

Epidural Space↗
PubMed2004

Percutaneous translumbar spinal cord compression injury in dogs from an angioplasty balloon: MR and histopathologic changes with balloon sizes and compression times.

BACKGROUND AND PURPOSE: Our previous model of spinal cord injury (SCI) included six dogs undergoing 30-minute compression with a balloon in the subarachnoid space. We determined whether various balloon sizes and compression times creates a gradation of injuries. METHODS: In 17 dogs (including our original six), angioplasty balloons 2, 4, or 7 mm in diameter (2 cm long) were inflated at T6 for 30, 120, or 240 minutes. T1- and T2-weighted, gadolinium-enhanced, and short-tau inversion recovery (STIR) MR images were obtained at 1.5 T. Spinal canal occlusion (SCO) was measured as balloon area-spinal cord area. Hematoxylin-eosin and beta amyloid precursor protein staining were performed to demonstrate hemorrhage and axonal injury, respectively. Injuries were scored as mild, moderate, or severe. Trends were assessed with one-way analysis of variance. RESULTS: SCO was 12.5-20% for 2-mm balloons, 28-56% for 4 mm, and 62-82% for 7 mm. No abnormalities were seen with SCO <30%. T1- and T2-weighted images had the poorest diagnostic performance; STIR images were best for predicting hemorrhage and axonal injury. Hemorrhage was demonstrated more frequently than was axonal injury. SCO (P < .0001) and hemorrhage (P = .002) significantly increased with balloon size. Longer inflation times tended to increase injuries for a given size, but differences were not significant. CONCLUSION: Compression injuries depended on the level of SCO. The compression times tested had less effect than the degree of compression. The value of 1.5-T MR imaging varied with the sequence and improved with contrast enhancement. STIR images showed SCIs not otherwise detected.

Angioplasty, Balloon↗