Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “STELLATE GANGLION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 973 records · Page 54Linked to original sources
PubMed2002

Sympathetic activity-mediated neuropathic facial pain following simple tooth extraction: a case report.

This is a report of a case of sympathetic activity-mediated neuropathic facial pain induced by a traumatic trigeminal nerve injury and by varicella zoster virus infection, following a simple tooth extraction. The patient had undergone extraction of the right lower third molar at a local dental clinic, and soon after the tooth extraction, she became aware of spontaneous pain in the right ear, right temporal region, and in the tooth socket. At our initial examination 30 days after the tooth extraction, the healing of the tooth socket was normal; however, the patient had a tingling and burning sensation (dysesthesia) and spontaneous pain of the right lower lip and the right temporal region, both of which were exacerbated by non-noxious stimuli (allodynia). The patient also showed paralysis of the marginal mandibular branch of the facial nerve, taste dysfunction, and increased varicella zoster serum titers. A diagnostic stellate ganglion block (SGB) 45 days after the tooth extraction using one percent lidocaine markedly alleviated the dysesthesia and allodynia. These symptoms are characteristic of neuropathic pain with sympathetic interaction. The patient was successfully treated with SGB and a tricyclic antidepressant.

Aged↗
PubMed1985

Hand injuries caused by high pressure injection. Contribution of loco-regional anaesthesia.

In a reported case of accidental high pressure injection of white spirit into a finger, the authors emphasise the great contribution of regional anaesthesia maintained from the initial trauma until the lesions are stable. Trauma to the hand caused by injection of paint or grease solvents results in tissue destruction and later necrosis and fibrosis. Secondary amputations are required in many cases. Regional anaesthesia of the stellate ganglion and brachial plexus produces analgesia and vasodilatation of peripheral arteries by inhibition of the sympathetic tone. This vasodilatation limits the necrotic process and promotes the supply of drugs to the injured tissues. Regional anaesthesia is of great benefit for surgical excision and avoids extended amputation.

Adult↗
PubMed1983

Vagal modulation of adrenergic effects on canine sinus and atrioventricular nodes.

Vagal stimulation modulates adrenergic neurotransmission at pre- and postjunctional sites. The purpose of this study was to test whether such multilevel cholinergic inhibition depressed sinus nodal automaticity and atrioventricular (AV) nodal conduction (A-H interval) in open-chest dogs anesthetized with chloralose. We compared the inhibitory effects of vagal stimulation when sinus nodal automaticity and AV nodal conduction were enhanced by bilateral stellate ganglia stimulation with comparable degrees of enhanced automaticity and conduction achieved by infusing norepinephrine and isoproterenol. We found that vagal stimulation prolonged in a frequency-dependent fashion sinus nodal cycle length and A-H interval more during stellate ganglion stimulation than during norepinephrine or isoproterenol infusion. Atropine eliminated all effects of vagal stimulation. These data provide functional evidence to support the concept that muscarinic modulation of adrenergic effects on sinus nodal cycle length and AV nodal conduction occurs at site(s) in addition to the postjunctional effector cell.

Animals↗
PubMed1997

Preliminary evidence for the evolution in complexity of heart rate dynamics during autonomic maturation in neonatal swine.

Previous studies suggest that the autonomic nervous system plays an important role in the generation of complex heart rate dynamics. Therefore, we hypothesized that the complexity (irregularity) of cardiac interbeat intervals would evolve with the maturation of autonomic innervation to the heart. Twelve healthy newborn piglets were implanted with ECG transmitters and studied at one or more different ages up to 33 days of age, the period during which pigs develop functional sympathetic innervation of the heart from the stellate ganglia. Three animals underwent right stellate ganglionectomy, two a left stellate ganglionectomy, two a right cardiac vagotomy and five a sham procedure. The statistic, approximate entropy (ApEn), was used to quantify the regularity of interbeat interval fluctuations. Sham-operated animals showed an increase in the standard deviation (SD) and irregularity (ApEn) of cardiac interval fluctuations with increasing age. Right stellate ganglionectomized piglets had lower interbeat interval ApEn values, but similar SD's by 26-27 days of age compared to sham-operated animals. Left stellate ganglionectomy, which affects cardiac inotropy rather than chronotropy, had no effect on cardiac interval irregularity, while vagotomy had an indeterminant effect. The increasing irregularity of interbeat interval dynamics during autonomic maturation and the apparent attenuation of heartbeat irregularity when right stellate ganglion innervation is interrupted, provides empirical support for the notion that complex heartbeat dynamics in the mature animal are the result of a network of autonomic neural pathways that enables an organism to adapt to stress.

Aging↗
PubMed1978

Categories of axons in the inferior cardiac nerve of the cat.

Myelinated and unmyelinated axons in the inferior cardiac nerve of the cat were examined to determine how many axons were (1) sensory, (2) preganglionic sympathetic, and (3) postganglionic sympathetic. In one group of cats, a segment was removed from the middle of the inferior cardiac nerve as a control, and the proximal and distal stumps of the nerve were examined one week later. In another group of cats, the control segment of nerve was removed and the first thoracic white ramus communicans and sympathetic trunk were cut proximal to the stellate ganglion, followed in one week by examination of the proximal and distal stumps of the inferior cardiac nerve. In still another group of cats, the first five thoracic spinal nerves were cut just distal to the dorsal root ganglion. The counts of myelinated and unmyelinated axons after these surgical procedures indicated that, in the cat inferior cardiac nerve, all or almost all of the approximately 30,000 unmyelinated axons and 10 percent of the myelinated axons are postganglionic sympathetic fibers, and that approximately 90 percent of the myelinated axons are sensory.

Animals↗
PubMed1997

Complex regional pain syndrome of the breast in a patient after breast reduction.

Complex regional pain syndrome (CRPS) is characterized by devastating pain, swelling, and cutaneous discoloration that result from vasomotor dysfunction caused by an abnormally accelerating sympathetic loop reflex after trauma or surgery. Although in the extremities CRPS is well documented as reflex sympathetic dystrophy, it only has been reported anecdotally in the breast after modified radical mastectomy and never reported after breast reduction. We report CRPS in the right breast of a 27-year-old woman after revision breast reduction surgery. The patient had signs of CRPS and symptoms of pain, swelling, epidermal scaling, and cutaneous temperature changes lasting more than 1 year. Liquid crystal thermographic scanning revealed a persistent, clinically significant hypothermic region in the affected breast. Intravenous phentolamine temporarily relieved the symptoms. Subsequent sympathetic blockade of the stellate ganglion alleviated chronic CRPS symptoms. Surgeons should be alert that CRPS may need to be considered in the differential diagnosis of chronic disproportionate pain after breast surgery. Early identification and treatment will help alleviate persistent CRPS symptoms and avoid soft-tissue changes.

Adult↗
PubMed2005

[Management and treatment of headache in the pain clinic].

Nerve block therapy is one of the non-pharmacological methods in headache treatment. Most pain clinics in Japan use nerve block therapy to treat pain together with pharmacological methods. Sensory nerve blocks such as the trigger point block, occipital nerve block, trigeminal nerve block, C-2, 3 spinal nerve block, etc., are effective for headache pain. One of the characteristic treatments of headache in the pain clinic in Japan is the stellate ganglion block(SGB). Although it has not been fully clarified why SGB is effective in treating headache, stabilization of the abnormal sympathetic nerve function, suppression of inflammation of vascular wall etc., are thought to be related to the effectiveness of SGB. Nerve block therapy is effective for the treatment of headache patients and offers us an important therapeutic option for treatment of headache pain.

Headache↗
PubMed1984

The nerve loops crossing below the subclavian artery and their anatomical variations.

60 dissections analysed the variability of three types of nerve loops crossing beneath the subclavian artery : Vieussens' annulus, the anastomotic ansa between the lower laryngeal nerve and the cervical sympathetic, and the anastomotic ansa between the phrenic nerve and the stellate ganglion. The classic disposition of these loops, situated below the artery and present simultaneously, was found in only 10% of the cases. Though Vieussens' annulus was present in most of the dissections, the anastomotic ansa between the cervical sympathetic and both the lower laryngeal nerve and the phrenic nerve corresponds more rarely to the conventional pattern.

Adult↗
PubMed1981

Autonomic interactions among subsidiary atrial foci.

Although the existence of a specific pacemaker hierarchy outside of the sinus node but within the atrium has been documented, little evidence regarding mechanisms controlling activity of these sites has been gathered. This investigation utilized an autologous perfusion of the sinus nodal artery, by way of the femoral artery, in order to suppress the sinus node cholinergically while unmasking latent atrial sites. Electrograms were recorded from the region of the sinus node and several atrial sites. Perfusion with small doses of acetylcholine and physostigmine unmasked pacemakers outside of the sinus and atrioventricular nodes, but within the atrium. Either vagal stimulation or topical acetylcholine on the area of the presumed pacemaker returned dominance gradually toward the sinus node. Stimulation of the right stellate ganglion accelerated the latent pacemaker but did not shift activation toward the sinus node. These results are consistent with the existence of subsidiary atrial pacemakers that appear to be highly sensitive to the effects of acetylcholine. This may represent one mechanism, in addition to overdrive suppression, that maintains pacemaker hierarchy within the right atrium.

Acetylcholine↗
PubMed1986

[Role of sympathetic vasoconstrictors in providing for the aerobic capacity of skeletal muscle].

The role of sympathetic vasoconstrictors in the mechanisms controlling the redistribution of blood flow to active muscle fibers in forearm muscles during and after handgrip with 10% MVC, was studied. Functional desympathization (blockade of the stellate ganglion and alpha 1-receptors with prazosin) led to shunting of active muscle fibers, subsequent activation of anaerobic glycolysis and decrease of aerobic working capacity. Increased concentration of lactate in the interstitial space of resting muscles causes analogous disturbances of blood flow redistribution and aerobic working capacity during contraction of these muscles.

Adult↗
PubMed2004

[Case of radial nerve injury induced by withdrawing a catheter from the cephalic vein].

There are many reports of neuropathic pain describing nerve injuries sustained by sticking or penetrating nerves by metal needles on venipuncture. However, there was no previous report of neuropathic pain caused by withdrawing a catheter from the vein as in this case. Neuropathic pain in this case was quickly cured by intravenous ketamine hydrochloride and stellate ganglion block. The neuropathic pain occurred when a medical student withdrew a catheter from the cephalic vein during clinical training. Clinical training of medical students is very important for medical education, but we must also recognize that this training involves many risks not only for patients but also for the students.

Adult↗
PubMed1991

In vivo monitoring of myocardial interstitial norepinephrine by dialysis technique.

To estimate local sympathetic nerve activity of the heart in vivo, we applied a dialysis technique to the heart and attempted to monitor norepinephrine levels in local myocardial interstitial fluid. The dialysis probe consisted of an 18 x 0.31 mm dialysis fiber with a 50,000-mol wt cutoff. When the probe was perfused at 5 microliters/min in vitro, the average relative recovery rate of norepinephrine was 31.3 +/- 0.6%. Dialysis probes were implanted in the left ventricular lateral wall of the beating heart in anesthetized cats and perfused with Ringer solution at 5 microliters/min. Dialysate norepinephrine concentration was measured using high-performance liquid chromatography with electrochemical detection. 1) After probe implantation, dialysate norepinephrine concentration decreased over the first 120 min and then reached an almost steady level (41.1 +/- 4.7 pg/ml). 2) Electrical stimulation of the left stellate ganglion increased dialysate norepinephrine concentration significantly, from control level of 39.0 +/- 5.8 to 82.0 +/- 7.7 pg/ml (P less than 0.01). After stimulation, dialysate norepinephrine concentration returned to the prestimulation level. The dialysis technique using high-performance liquid chromatography permits monitoring of norepinephrine levels in local myocardial interstitial fluid and detection of changes in local cardiac sympathetic nerve activity in vivo.

Analysis of Variance↗
PubMed1984

Chronotropic, inotropic, and coronary artery blood flow responses to stimulation of specific canine sympathetic nerves and ganglia.

Electrical stimulation of the major sympathetic cardiac nerves and ganglia in chloralose-anesthetized, open-chest dogs elicited specific changes in heart rate, coronary blood flow, regional intramyocardial pressure, or intraventricular pressure. The effects produced by stimulation of a cardiac nerve were similar to, but never greater than those produced by stimulation of the ipsilateral stellate ganglion. Coronary blood flow was increased when neural stimulation increased intramyocardial pressure. In contrast, coronary blood flow was not altered significantly when neural stimulation induced tachycardia without increasing intramyocardial pressure. It is concluded that in the intact heart, electrical stimulation of the sympathetic cardiac nerves or ganglia increases coronary blood flow by augmenting intramyocardial pressure, not chronotropism.

Animals↗
PubMed1997

[A case of reflex sympathetic dystrophy following a retinous surgery].

We present a case of a 54-year-old female with post-operative severe continuous ocular pain which occurred 3 months after retinal operation. Her general and mental conditions were good. We diagnosed it reflex sympathetic dystrophy and treated with stellate ganglion blocks (SGB) and continuous cervical epidural blocks. SGB and continuous cervical epidural blocks were effective. With increasing numbers of retinal surgery in recent years, more patients will suffer from postoperative ocular pain. We conclude that SGB or epidural block is useful for the therapy of ocular pain which can not be controlled by drugs and other therapy.

Analgesia, Epidural↗
PubMed1975

Complications of phenol neuroloysis.

Phenolic stellate ganglion blockade caused triparesis in one patient, and phenolic neurolysis of cervical posterior roots caused respiratory arrest in another. These complications illustrate the dangers of the spread of phenol beyond the intended site of neurolysis with resultant local anesthesia, direct neural damage, vascular damage, and infarcts.

Aged↗
PubMed2005

Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling.

Sympathetic neurons are generated through a succession of differentiation steps that initially lead to noradrenergic neurons innervating different peripheral target tissues. Specific targets, like sweat glands in rodent footpads, induce a change from noradrenergic to cholinergic transmitter phenotype. Here, we show that cytokines acting through the gp 130 receptor are present in sweat glands. Selective elimination of the gp 130 receptor in sympathetic neurons prevents the acquisition of cholinergic and peptidergic features (VAChT, ChT1, VIP) without affecting other properties of sweat gland innervation. The vast majority of cholinergic neurons in the stellate ganglion, generated postnatally, are absent in gp 130-deficient mice. These results demonstrate an essential role of gp 130-signaling in the target-dependent specification of the cholinergic neurotransmitter phenotype.

Adrenergic Fibers↗
PubMed1984

[Mechanism of the intracardiac interactions of the vagus and sympathetic nerves: is a serotoninergic mechanism possible?].

A study was made of the conditions of the occurrence and mechanisms of the enhancement by the sympathetic nerve of the vagus-induced inhibition of rabbit heart work. It was discovered that to obtain such a phenomenon, it is necessary that stimulation of the stellate ganglion be made in the presence of perithreshold stimulation of the vagus after blockade of beta-adrenoreceptors. The inhibitory effect was not abolished by dihydroergotoxin but was blocked by promedol, aminazine and diprazine. It is suggested that the serotoninergic component is involved in the mechanism of the enhancement of the vagus-induced inhibition that occurs during stimulation of the sympathetic nerve.

Animals↗
PubMed1996

[Management of severe pain after extended maxillectomy in a patient with carcinoma of the maxillary sinus].

We treated a 65 year-old man with severe facial pain after extended maxillectomy due to carcinoma of maxillar sinus. He had been suffering from pain at rest, on mastication, or at treatment of surgical wound. Various kinds of analgesics had been tried, but his pain did not disappear. At 17 weeks after the operation, he came to our pain clinic. Because his pain was thought to be due to reflex sympathetic dystrophy (RSD), stellate ganglion blocks (SGB) were performed. After 5 administrations of SGB, pain was reduced markedly but the pain at treatment of wound persisted. We thought that persistent pain would need trigeminal nerve block. Then Gasserian ganglion block was performed directly through an open wound after the operation. After the Gasserian ganglion block, the pain was diminished remarkably. He could tolerate procedures for facial prosthesis. Pain control after the operation in this patient was very efficient to improve his quality of life. Serum concentrations of catecholamines, serotonin and substance P were measured. The levels of norepinephrine and serotonin are related to the mechanism of pain as seen in this patient.

Aged↗