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At least 973 records · Page 54Linked to original sources

[Radiotherapy of malignant tumors in children].

Radiation treatment is widely used in pediatric cancer patients. Much attention should be paid to preserve the function and structure of normal organs and tissues adjacent to tumor. To achieve this goal, optimal treatment modality should be chosen and closely followed. Certain peculiarities of irradiation of children, particularly, infants should be considered. These include the use of medication sleep. Drug combinations to be used to prepare patients for radiotherapy are discussed.

Age Factors↗

[Various possibilities of reconstruction of the thoracic wall in radiation defects].

Reconstruction of the thoracic wall is often necessary after cancer surgery of the breast or irradiation. The resulting large defects often cause an instable thoracic wall. To reconstruct stability, we can use fascia or dura mater. The large defects can be closed either by latissimus flap, or, if the thoracodorsal artery is destroyed, which is often the case by rotating flaps according to the technique of Schrudde or Bohmert, in very rare cases by distant flaps from the neighbouring upper arm.

Humans↗

[The therapy of acute radiogenic epitheliolysis with a dressing of hydrocolloids and polymers (Biofilm). A report on clinical experience].

Acute skin lesions following radiotherapy are uncomfortable and unacceptable side effects. They are observed predominantly after high surface doses as in conventional roentgen or electron beam therapy. To accelerate the wound healing we tested a bandage consisting of hydrocolloids and polymers, which is permeable for gas and water. Handling, compatibility and effectiveness of this plaster were tested in this study. According to the RTOG scoring system 19 irradiated fields with grade II to IV lesions were treated. Densitometric measurements of verification films with and without Biofilm showed no energy absorption. The bandage was comfortable for the patients and easy to handle.

Acute Disease↗

[Experience in treating the victims of the accident at the Chernobyl Atomic Electric Power Station and the immediate disease outcomes].

The paper is concerned with the results of therapy of 115 patients with acute radiation syndrome after the Chernobyl accident. The chief methods of the effective therapy of bone marrow syndrome are antimicrobial drugs and fresh donor platelet mass transfusions. Hemopoietic stem cell transplantation (allogenic bone marrow or embryonic hepatocytes) is indicated and effective in a very limited number of patients in accident irradiation. Severe beta-burns of the skin remain an unsolved problem as a result of their spreading. Organizational principles of therapy of a great number of patients with acute radiation syndrome in a specialized hospital were described.

Accidents↗

[Clinial picture and localization of skin metastasis of visceral carcinomas].

Seven cases with secondary skin carcinomas are described. The primary tumor was located at the tongue, the larynx, the thyroid, the abdomen, the ovaries, the collum uteri and the rectum. From the literature 60 other patients with secundary skin carcinomas and 100 primary carcinomas were evaluated. Clinical evidences for a secundary skin carcinoma are: unusual localization, multiple occurrence and an even surface. It was examined whether the localization of the secundary skin tumor refers to the localization of the primary tumor.

Abdominal Neoplasms↗

Atypical iatrogenic presentations of molluscum contagiosum.

Description of two patients with atypical linear eruption of molluscum contagiosum in the places previously treated with iontophoresis of hydrocortisone for Bell's palsy, and with radiotherapy for malignant granulomatosis. The causal nexus of the treatment used previously and the appearance of described changes is considered.

Adult↗

Impaired skin integrity related to radiation therapy.

Skin reactions associated with radiation therapy require frequent nursing assessment and intervention. Preventive interventions and early management can minimize the severity of the skin reaction. With the understanding of the pathogenesis of radiation skin reactions, the ET nurse can determine who is at risk and then implement preventive measures. Because radiation treatment is fractionated, skin reactions do not usually occur until midway through the course of therapy and will subside within a few weeks after completion of radiation. Many patients and their families still fear that radiation causes severe burns. Teaching and anticipatory guidance by the ET nurse is needed to assist patients and their families to overcome this fear, and to educate them on preventive skin care regimens.

Humans↗

[The treatment of laryngeal cancer by using local hyperthermia].

Potentiation of the effect of radiation and combined treatment of laryngeal cancer by local hyperthermia was studied in 43 patients. In 51 cases of the control group (radiotherapy), conventionally-dynamic fractionation of dose was used. At 32 Gy, complete or partial regression of tumor was observed in 72.1% in the study group and 64.7% of controls. An increased frequency of radiation-induced damage of the oral mucosa was observed whereas radiation epidermitis did not occur. Three-year relapse-free survival following a course of radical thermoradiotherapy was as high as 76.5% compared to 40% in controls. Overall three-year survival (including the results of combined treatment and treatment for relapse) increased from 66.7 to 83.3%.

Adult↗