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At least 973 records · Page 54Linked to original sources

Detection of cell surface antigen in cancer of renal pelvis and ureter.

Thirty-five patients with transitional cell carcinoma of the renal pelvis or ureter of all stages and grades were studied for presence or absence of ABO(H) antigens utilizing an improved technique for staining and preserving the slides. Seventy per cent of the grade I tumors retained their antigens. Patients with antigen present had a longer duration of disease-free interval. Specific red cell adherence (SRCA) may predict the clinical course of patients with low-stage, low-grade transitional cell carcinomas and may be helpful in selecting patients for optimal therapy.

ABO Blood-Group System↗

Carcinosarcoma of renal pelvis.

A new case of carcinosarcoma of the renal pelvis is reported and the literature reviewed. This tumor occurs in patients over sixty years of age. Three patients died of the disease in one year, and 2 showed six-month and two-year disease-free survival after nephrectomy.

Aged↗

Surgical management of benign renal cysts causing obstruction of renal pelvis.

During the last fifteen years, 6 adult patients were treated in whom obstruction of the ureteropelvic junction or the renal pelvis was caused by a benign renal cyst. The cyst extended from the renal hilus in each case and had turgor sufficient to overcome the pressure of intrapelvic urine. Operative unroofing of the cyst relieved the obstruction in each. In 5 of 6 cases, the postoperative radiographic appearance of the kidney showed marked improvement. Each patient was followed for at least five years, and no recurrence of the obstruction was noted. Operative treatment is recommended when a renal cyst causes significant obstruction of the major calyceal or renal pelvic outflow.

Female↗

Hyperkeratotic squamous epithelium of pelvis and ureter in solitary kidney.

A case of hyperkeratotic squamous epithelium of the distal renal pelvis and ureter, clinically identifiable as leukoplakia, is reported in a solitary kidney. Because of the need to conserve renal parenchyma in this patient, the lesion was treated conservatively at operation after careful exploration and full thickness biopsy failed to reveal malignancy. Close monitoring of this potentially premalignant lesion has documented no progression at twenty-five months.

Female↗

Squamous cell carcinoma of renal pelvis.

Squamous carcinoma of the renal pelvis was diagnosed in only 11 of 2,166 renal tumors (0.5%) seen over a twenty-seven-year period. The combination of an insidious onset and a prolonged duration of symptoms (median: 5 months) resulted in all patients having invasive disease at diagnosis. Ten patients died two to twenty-eight months after diagnosis (median survival: 5 months), and only 1 patient is currently alive at nine months. We conclude that the treatment of choice is radical nephrectomy followed by adjuvant chemotherapy.

Adult↗

Spontaneous rupture of hydronephrotic renal pelvis with massive hemorrhage.

Spontaneous rupture of a hydronephrotic renal pelvis with massive hemorrhage presents as a perplexing diagnostic challenge to the urologist. The preoperative distinction between this condition and spontaneous rupture of the kidney (Wunderlich disease) may prove uncertain or equivocal despite the application of exhaustive diagnostic modalities. Surgical intervention should follow initial stabilization, and nephrectomy has been the procedure of choice.

Aged↗

Renal adenocarcinoma metastasizing to contralateral renal pelvis.

Ureteric metastases from renal adenocarcinoma are uncommon and occur predominantly in the residual ipsilateral ureteric stump. We report on a patient with renal adenocarcinoma metastasizing to the contralateral renal pelvis and the clinical problems involved.

Adenocarcinoma↗

Simplified infusion method for 10% hemiacidrin irrigation of renal pelvis.

A variable pressure volumetric pump was used for 10% hemiacidrin irrigation of the renal pelvis in 7 renal units (6 patients) with struvite calculi after initial percutaneous debulking and extracorporeal shock-wave lithotripsy (ESWL). The pump provided a constant display of intrapelvic infusion pressure, and an alarm which signaled if a preset maximum infusion pressure was exceeded. Compared with standard open manometer monitoring of intrapelvic pressure, this closed system of irrigation eliminates the problems associated with time-consuming assembly and maintenance, irrigant spillage, and system contamination. At the completion of therapy, 5 renal units were completely stone-free while 2 had only minimal residual caliceal "dust." Complications were minor and few in number. We conclude that a variable pressure volumetric pump provides excellent clinical results and safely simplifies irrigation for percutaneous chemolysis of struvite calculi.

Citrates↗

Primary mucinous adenocarcinoma of renal pelvis in solitary pelvic kidney.

Mucinous adenocarcinoma of the renal pelvis is a rare tumor. We report the case of a fifty-three-year-old man with this unusual cancer and review the literature. Usual features of this tumor include long duration of symptoms, an association with calculi and hydronephrosis, and a preoperative appearance of an inflammatory condition.

Adenocarcinoma, Mucinous↗

Transitional cell carcinoma of the renal pelvis with ovarian metastasis.

This article describes the first reported case of a primary transitional cell carcinoma of the renal pelvis metastatic to the ovary. The clinical presentation in our patient was similar to that of a primary ovarian carcinoma. The differential diagnosis of a primary or metastatic transitional cell carcinoma in the ovary is important and has therapeutic as well as prognostic implications.

Carcinoma, Transitional Cell↗

Nonreciprocal chromosome translocation t(5;14) in cancers of the kidney: adenocarcinoma of the renal parenchyma and transitional cell carcinoma of the kidney pelvis.

Chromosome studies were done on an adenocarcinoma of the kidney and a transitional cell carcinoma of the kidney. The adenocarcinoma was in the renal parenchyma, whereas the transitional cell carcinoma was in the kidney pelvis. The adenocarcinoma was moderately well differentiated, and the transitional cell tumor was poorly differentiated. The adenocarcinoma was hypotetraploid, with 69-75 chromosomes per cell, and the transitional cell carcinoma was pseudodiploid, with 46 chromosomes. Both tumors showed a nonreciprocal t(5;14) translocation that resulted in a 5q- and a 14q+ chromosome with loss of 14q material. The breakpoints were in bands 5q13 and 14q22. Both tumors also contained an extra 5q- chromosome. The oncogene c-fms is normally situated in band 5q34 and so may have been translocated onto 14q, although whether it has been activated is conjectural. The t(5;14) translocation may be another tissue-specific cancer chromosome change.

Adult↗

Bladder cooling in patients treated with regional hyperthermia of the pelvis using an annular phased array.

Regional hyperthermia for the treatment of deep seated tumors is often limited by excessive heating of normal tissues, usually with associated patient pain and/or discomfort. The use of bladder cooling via perfusion of distilled water through a modified tri-lumen irrigation catheter as an aid to circumventing this problem in one anatomical region is described. This relatively simple technique provided rapid pain relief and permitted completion of the hyperthermia treatment in a satisfactory manner. Modifications of this technique may permit selective heating and/or cooling of the bladder during regional hyperthermia treatments in the pelvis.

Adult↗