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[Telemedicine--technology, application, evaluation and prospect].

With the information society drawing near, the pattern of medical treatment is changing. Telemedicine is now carrying out many purposes such as family health care, first aid, expert consultation, long-distance intervene and learning communication in it's particular mode. This article will enter into some engineering-technology methods of medical information transmission (including data, sound and image), introduce several application field of telemedicine , evaluate the potential benefit, virtue and some problems which are likely to arise in the implement of telemedicine, and forecast the development of telemedicine in the future.

Aerospace Medicine↗

[An internet based medical communication server].

The telemedicine and medical conference usually need multi-point to multi-point communication. Because the communication users can be patients, specialists or medical centers, they have different communication ratios and different physical connection, therefore, this kind of communication is complicated and limited by the communication ratios. In this paper, to meet the requirements of medical communication, we presented a concept of medical communication server which is able to receive data packages and deliver them according to the request of clients, and described its implementation in Windows 95 environment by using Windows Sockets.

Computer Systems↗

Integrating medical applications in an open architecture through generic and reusable components.

Allowing exchange of information and cooperation among network-wide distributed and heterogeneous applications is a major need of current health care information systems. It forces the development of open and modular integration architectures. Major issues in the development include defining a flexible and robust federation model, developing interaction and communication facilities as well as the mechanism insuring semantic interoperability. We developed generic and reusable software components to ease the construction of any integration platform. The Pilot and the Mediator Service components facilitate the execution of services and the meaningful transformation of information. They have been tested in the context of the SynEx European project to construct a multi-agents based integration architecture. The possibility of such architectures to take into account the issue of semantic interoperability is further discussed.

Computer Communication Networks↗

[What is bioinformatics?].

Yet bioinformatics has neither clear definition nor proper Japanese equivalent for this word. Bioinformatics is mainly composed of two fields or disciplines; one is computer and information technology as a tool for analyzing massive data such as genome and proteome, and the other one is research for the integrated biology based on the knowledge of genome. Classical and narrow-sense bioinformatics corresponds to the former. The latter called new bioinformatics aims to understand living thing as a whole, where both genome information and mathematical model play complimentary roles. From now the postgenome area on, this new bioinformatics may give novel perspective about living thing, biology and human.

Computational Biology↗

Health care, ethics, and information technologies.

This essay explores how ethics, computing, and health care intersect in medical informatics. It discusses the power technology places in the hands of health care professionals and the ethical problems they may encounter as a result of that power.

Decision Making↗

A wireless mobile health-related quality of life assessment.

Self-administered waiting room questionnaires are popular tools for gathering health information from patients, but they require optical scanning or manual data entry to obtain survey results. The application described here eliminates those extra steps by inputting the results into a remote database directly through wireless connection, and the assessment can be finished easily anywhere in the clinic through a mobile platform. A measure of health-related quality of life, the SF-8 Health Survey, was used in developing this application for using in the clinical setting. It has only eight questions measuring each of the eight domains of health in the longer SF-36 Health Survey.

Computer Communication Networks↗

Integrating clinical information in NHS Scotland: the role of Scottish Care Information Store.

A key plank in NHS Scotland's information management and technology (IM&T) eHealth Strategy is the web-based system known as Scottish Care Information (SCI) Store, which gives primary and secondary care clinicians access to core clinical information. There is one SCI Store in each of the 15 NHS Board areas. At present all GP practices in 11 of these areas have access to SCI Stores for test results. Work is underway to augment the Stores with clinical letters and GP summary data. Strategically, SCI Store is seen as the ubiquitous element in our eHealth Strategy which will allow information to be shared across Scotland in a secure and reliable way.

Computer Communication Networks↗

A web-based central diagnostic data repository.

A central repository for diagnostic information about individual patients was created as a service to diagnostic laboratories participating in the Compentence Network for Acute and Chronic Leukemias in order to support health care delivery to patients suffering from leukemia. During the diagnostic phase several specialised laboratories perform different assays on samples from the same patient. The use of these assays in the diagnostic process and during the treatment phase may be improved in terms of both rapid delivery and cost if any one laboratory is aware of preliminary or final results from the assay carried out in other laboratories. In order to support a more efficient communication of these results, a central diagnostic data repository (CDDR) was created and web-based user interface was developed. Currently, the CDDR maintains documents in the form of portable document format (PDF) files. Several other formats are accepted and converted automatically upon entry. Patient identification is accomplished by pseudonym rather than proper name and the data is held on the CDDR for a limited time interval to accommodate the stringent privacy regulations in Germany. The principle operation of a CDDR may also be applied to the diagnostic or therapeutic process of other diseases.

Acute Disease↗

Leveraging intelligent agents for knowledge discovery from heterogeneous healthcare data repositories.

This paper presents a case for an intelligent agent based framework for knowledge discovery in a distributed healthcare environment comprising multiple heterogeneous healthcare data repositories. Data-mediated knowledge discovery, especially from multiple heterogeneous data resources, is a tedious process and imposes significant operational constraints on end-users. We demonstrate that autonomous, reactive and proactive intelligent agents provide an opportunity to generate end-user oriented, packaged, value-added decision-support/strategic planning services for healthcare professionals, manages and policy makers, without the need for a priori technical knowledge. Since effective healthcare is grounded in good communication, experience sharing, continuous learning and proactive actions, we use intelligent agents to implement an Agent based Data Mining Infostructure that provides a suite of healthcare-oriented decision-support/strategic planning services.

Efficiency, Organizational↗

Multimodal retinal image registration for optic disk segmentation.

OBJECTIVES: The analysis of the optic disk morphology with the means of the scanning laser tomography is an important step for glaucoma diagnosis. A method we developed for optic disk segmentation in images of the scanning laser tomograph is limited by noise, non-uniform illumination and presence of blood vessels. Inspired by recent medical research, we wanted to develop a tool for improving optic disk segmentation by registration of images of the scanning laser tomograph and color fundus photographs and by applying a method we developed for optic disk segmentation in color fundus photographs. METHODS: The segmentation of the optic disk for glaucoma diagnosis in images of the scanning laser tomograph is based on morphological operations, detection of anatomical structures and active contours and has been described in a previous paper. The segmentation of the optic disk in the fundus photographs is based on nonlinear filtering, Canny edge detector and a modified Hough transform. The registration is based on mutual information using simulated annealing for finding maxima. RESULTS: The registration was successful 86.8% of the time when tested on 174 images. Results of the registration have shown a very low displacement error of a maximum of about 5 pixels. The correctness of the registration was manually evaluated by measuring distances between the real vessel borders and those from the registered image. CONCLUSIONS: We have developed a method for the registration of images of the scanning laser tomograph and fundus photographs. Our first experiments showed that the optic disk segmentation could be improved by fused information from both image modalities.

Fundus Oculi↗

Modeling cancer registration processes with an enhanced activity diagram.

OBJECTIVES: Adequate instruments are needed to reflect the complexity of routine cancer registry operations properly in a business model. The activity diagram is a key instrument of the Unified Modeling Language (UML) for the modeling of business processes. The authors aim to improve descriptions of processes in cancer registration, as well as in other public health domains, through the enhancements of an activity diagram notation within the standard semantics of UML. METHODS: The authors introduced the practical approach to enhance a conventional UML activity diagram, complementing it with the following business process concepts: timeline, duration for individual activities, responsibilities for individual activities within swimlanes, and descriptive text. RESULTS: The authors used an enhanced activity diagram for modeling surveillance processes in the cancer registration domain. Specific example illustrates the use of an enhanced activity diagram to visualize a process of linking cancer registry records with external mortality files. CONCLUSIONS: Enhanced activity diagram allows for the addition of more business concepts to a single diagram and can improve descriptions of processes in cancer registration, as well as in other domains. Additional features of an enhanced activity diagram allow to advance the visualization of cancer registration processes. That, in turn, promotes the clarification of issues related to the process timeline, responsibilities for particular operations, and collaborations among process participants. Our first experiences in a cancer registry best practices development workshop setting support the usefulness of such an approach.

Computer Simulation↗

A gridified protein structure prediction system "Rokky-G" and its implementation issues.

In recent years, simulation using computer systems has been of increasing importance in the life sciences. We have developed a system called "Rokky-G" that facilitates a protein structure prediction strategy called "Rokky" on Grid systems. Rokky-G provides the framework of protein structure prediction on the Grid. In this paper we discuss the architecture of Rokky-G and implementation issues identified in order to obtain highly reliable results.

Algorithms↗

Consumers' use of the internet for health information.

Although health information is one of the most frequently sought subjects on the Internet, little research has been performed in this area. This study was designed to examine the use of the Internet for health information by the consumers. A questionnaire was administered to a sample of 212 consumers who were using health care. Only small percentages of the consumers accessed the Internet for health information. This result indicates that different marketing strategies based on geographic characteristics should be developed for consumers who wish to get health care information.

Community Participation↗