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At least 973 records · Page 54Linked to original sources
PubMed1992

Cardiac fibroma. Long-term fate after excision.

Between 1980 and July 1983 three infants and children with cardiac fibromas underwent surgical resection at Kobe Children's Hospital. Two of them survived and have an excellent clinical result 6 years and 7 years postoperatively. The results of late follow-up with the use of 24-hour dynamic electrocardiography, two-dimensional echocardiography, thallium-201 myocardial scintillation scan, and technetium 99m sodium pertechnetate-gated blood pool imaging have proved that the patients are free of arrhythmic episodes, free of recurrence of tumor, have no significant myocardial perfusion defect, and have normal left ventricular function.

Child↗
PubMed1991

[Desmoid fibroma of soft tissues of extra-abdominal site: review of the literature apropos of a case of a tumor situated at the posterior side of the thigh].

The authors report a case of desmoid fibroma on the posterior surface of the thigh in a woman during the post-partum period. This is a rare site for this tumour. CT scan combined with MRI appears to be useful for diagnosis. Treatment is strictly surgical, but depends on the histological benign nature and the local malignancy. Surgery is generally conservative with risks of recurrence and occasionally amputation is necessary.

Adult↗
PubMedDate not supplied

Calcifying aponeurotic fibroma.

The calcifying aponeurotic fibroma is a rare, benign neoplasm that often presents in the palms or soles of young male children. Microscopic examination of this tumor demonstrates atypical fibroblasts, foci of calcification, and patches of chondroid differentiation. The neoplasm's highly cellular architecture, locally aggressive growth pattern, and tendency to recur may lead to a misdiagnosis of fibrosarcoma and subsequent amputation. This manuscript presents a review of the literature and a unique case involving the digits of the foot.

Calcinosis↗
PubMed1991

Pleomorphic fibroma of skin. A case report and immunohistochemical study.

An immunohistochemical study of a clinically benin but cytologically atypical mesenchymal lesion of the skin is presented. This lesion has been previously reported as pleomorphic fibroma and was shown to follow a benign course with a potential for local recurrence. These lesions contain occasional markedly atypical enlarged spindle cells with anaplastic-appearing nuclei. Nonmirror image mitotic figures may be present. Histogenesis of this neoplasm remains controversial with a fibroblastic origin being favored by previous authors. Our immunohistochemical findings would support this conclusion.

Adult↗
PubMed1991

Healing of a large nonossifying fibroma after grafting with bone matrix and marrow. A case report.

Healing of a large tibial nonossifying fibroma in a 12-year-old girl occurred following excision, curettage, and filling of the bony defect with human demineralized bone matrix powder mixed with a small quantity of the patient's bone marrow. The use of this graft composite was successful in the treatment of the lesion and reduced the potential risk and morbidity associated with pediatric orthopedic surgical procedures with autogeneic iliac crest and other bone grafts.

Bone Marrow Transplantation↗
PubMed1978

[Bronchopulmonary hamartomas, chondromas, fibromas and myxomas].

The observation of 23 bronchopulmonary hamartomas, 9 chondromas, one fibroma and one myxoma has provided insight into the particularities of these tumors. The group of hamartomas, tumors of "erroneous mixture of tissue", included 20 cases which can be considered a malformation of the entodermal bronchial anlage, and 3 cases which can be regarded as a malformation of the mesenchymal anlage. The first type consists of multiple cleft-like spaces surrounded by ciliated and cuboidal epithelium. There are no alveolar cells. Cartilaginous, fibrous, myxomatous and lipomatous tissue and lymphocytes are also found. The second type consists mainly of undifferentiated mesenchymal cells with tubules, lined by cuboidal epithelial cells or an intestinal type of mucus-secreting epithelium. There may be some immature alveoli, but no ciliated epithelium is found. In contrast to the hamartomas, the chondromas are not derived from a dysontogenetic malformation of the bronchopulmonary tissue but are tumors which develop directly from the bronchial cartilage and are for this reason mainly localized in the endobronchial region. A special form seen in one case is association of pulmonary chondromas, gastric leiomyomas or leiosarcomas and extra-adrenal paraganglioma, though the latter is not always present.

Adult↗
PubMed1991

Ossifying fibroma of the long bones. Radiological diagnosis, differential diagnosis and management implications.

We report a case of ossifying fibroma of the long bones (OFLB). This lesion, occurring mainly during the first decade of life, typically affects the tibial diaphysis and clinically presents as a painless bony enlargement. Radiographic features include an osteolytic cortical expansion, containing diffuse calcifications, and separated from the medullary by a thick cortical rim. CT appears to be the examination of choice to define these signs and permits differentiation from monostotic fibrous dysplasia and from adamantinoma (by demonstrating the presence or absence of diffuse high attenuation values). The importance of making the differential diagnosis is stressed, as prognosis and management of OFLB, fibrous dysplasia and adamantinoma may vary considerably.

Bone Neoplasms↗
PubMedDate not supplied

[Hereditary intraoral fibromas and exostoses].

The formation of exostoses of the upper and lower jaw is a frequent finding and should be treated for esthetic and functional reasons. An unusual case of severe palatal fibromas and concomitant vestibular exostosis in a 36-year-old woman is presented. Identical symptoms are found in the patient's father and her 8-year-old daughter.

Adult↗
PubMed1990

Hereditary hyperparathyroidism and multiple ossifying jaw fibromas: a clinically and genetically distinct syndrome.

A large previously reported family with hyperparathyroidism has been reinvestigated recently because of the occurrence of multiple ossifying jaw fibromas in two affected members of the third generation similar to the jaw tumors of four of five affected members of the first generation. These maxillary and mandibular tumors can be differentiated from the "brown tumors" of hyperparathyroidism because they can appear and enlarge even though the hypercalcemia is surgically corrected. These tumors are histologically distinct fibroosseous lesions without the giant cells seen in "brown tumors." The parathyroid enlargement was mostly uniglandular, with multiple tumors found occasionally. Studies in DNA linkage were performed within this large family and a similar family in Houston to determine if the gene for this syndrome, termed HRPT2, is linked to DNA markers on chromosome 11, to which the gene for multiple endocrine neoplasia (MEN) type 1 has been linked. (This linkage is supported by our findings in one family with MEN 1 reported here.) Linkage studies were also performed with markers on chromosome 10, to which the genes for MEN 2A and MEN 2B have been linked. Evidence against close linkage with chromosome 10 and chromosome 11 markers suggests that this clinically distinct syndrome is also genetically distinct.

Female↗
PubMed1990

[A case of ossifying fibroma].

A case of ossifying fibroma of the maxillary left suspected as fibrous dysplasia was reported. The patient was a 21 year-old man complaining of a swelling of the gingiva at the left upper molar region. X-ray examination showed a border distinct imradiolucent, a ground glass appearance in partially at the left maxillary region. In the histological findings, the specimen showed a large number of comparatively ripe bone that suspected as Osteoma. At about 3 years postoperatively, no evidence of recurrent has appeared.

Adult↗
PubMed1978

Common membrane neoantigens on bovine papilloma virus-induced fibroma cells from cattle and horses.

Cultured cells from bovine papilloma virus (BPV)-induced fibroblastic tumors and normal dermis of cattle, horses, and hamsters were examined for cell membrane or internal neoantigens, using the indirect immunofluorescence technique. Sera from cattle and horses bearing BPV-induced fibromas cross reacted with cell membranes of tumor, but not with normal dermal cells of both species. The reaction could be blocked with homologous, but not heterologous, serum of these 2 species. Immunofluorescence was not detected with sera from hamsters bearing BPV-induced sarcomas if incubated with bovine, equine, or hamster cells. Internal neoantigens were not found in any of the acetone-fixed tumor cells, using sera from the 3 species. Both tumor and normal cells were all found free of BPV antigen, using direct immunofluorescence.

Animals↗
PubMed1979

Ultrastructure of the myocardial fibroma.

The ultrastructure of a myocardial tumor, referred to by a variety of names, which most currently is myocardial fibroma, has been studied. Although the tumor cells did not have the structure associated with protein synthesizing cells or active fibroblasts, there was evidence that they were participating in formation of the abundant stroma rich in collagen and elastic fibers in varying stages of maturity. The morphology of the stromal elements was similar to that in the surrounding myocardium and that described in the "normal" heart but differed from the elastica described in fibroelastosis.

Cell Membrane↗
PubMed1979

A myofibroblastic tumor. Infantile digital fibroma (recurrent digital fibrous tumor of childhood).

Infantile digital fibromas are distinctive tumors both clinically and morphologically. A unique light microscopic features in the presence of intracytoplasmic, spherical, eosinophilic inclusion bodies. Previous electron microscopic studies have shown these bodies to consist of fibrils; bundles of fibrils have also been described in the cytoplasm. We have examined one such tumor, confirmed earlier findings, and established that the component cells are typical myofibroblasts. The latter are a variety of fibroblasts first described in granulation tissue; they are endowed with contractile properties and are characterized ultrastructurally by bundles of fibrils containing "dense bodies" such as are found in smooth muscle cells. Since our case is identical to those previously described, we propose that this tumor be called infantile digital myofibroblastoma.

Basement Membrane↗
PubMed1990

Nonossifying fibroma of bone: a case report.

An atypical case of nonossifying fibroma involving the femoral neck of a 7-year-old white male is presented. The radiographic characteristics of the lesion were consistent with this diagnosis, although the location is rare. The differential diagnosis included fibrous dysplasia, unicameral bone cyst, chondroblastoma, and eosinophilic granuloma. A final diagnosis was obtained through tissue biopsy and histopathologic review.

Child↗
PubMedDate not supplied

[Fibroma of the tendon sheath. Description of a case].

One case of fibroma of tendon sheath is described. This tumor is a distinct entity with a characteristic location and histological appearance. The lesion must be distinguished from giant cell tumor of tendon sheath, nodular fasciitis and fibrous histiocytoma. Recurrence rate is 24%. Local excision is the treatment of choice for primary and recurrent lesions.

Adult↗
PubMed1990

Desmoplastic fibroma of bone: report of one case and review of the literature.

A case of a primary desmoplastic fibroma of bone has been presented with a complete review of the world's literature on the subject. Our case represents the one hundred and twenty seventh case (127th) reported. The usual aggressive local growth and the classical radiological and histological characteristics are very well depicted in the case. It represents the first case of this tumor of bone reported in Puerto Rico. No recurrence is evident twenty months after wide excision and intercallary bone graft.

Bone Neoplasms↗