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Human mineralized bone in extraction sites before implant placement: preliminary results.

BACKGROUND: Bone loss after tooth extraction may prevent dental implant placement. Human mineralized bone grafts can be used to restore bone volume and allow for tooth replacement with dental implants. METHODS: The authors grafted 22 sites in 18 patients with human mineralized bone after tooth extraction. They allowed molar sites 16 weeks for graft healing, placed the implants and restored them with a final crown after a four-month integration period. Single-rooted maxillary sites received implants and immediate placement of provisional crowns or underwent a delayed two-stage restoration approach. The authors used radiographs and clinical examinations to evaluate the results. RESULTS: All of the sites were restored successfully with a single-tooth implant restoration. Periapical radiographs indicated that the crestal bone levels were limited to the first thread of the implants or slightly coronal to the first thread of the implant. Clinical evaluation indicated excellent gingival health around the provisional and final restorations, without obvious gingival migration. CONCLUSIONS: The use of human mineralized bone may have significant potential to reconstruct missing bone resulting from tooth extraction and to preserve bone after tooth extraction. In addition, healed bone graft sites seem to be able to support immediate placement of a provisional crown and implant restorations. CLINICAL IMPLICATIONS: Patients who are having teeth extracted may become candidates for implant restorations when the sites are appropriately grafted to preserve and reconstruct bone volume, thus allowing for more options for reconstructing the missing tooth site.

Alveolar Ridge Augmentation↗

[Periodontal considerations related to extractions].

During any tooth extraction, the dentist has to think about healing problems in order to maintain as much bone as possible afterwards. Careful and well done extractions using classical techniques allow maximum bone preservation in normal cases. At minima alveolectomy techniques are a guarantee against tremendous bone loss. After healing and before prosthetic rehabilitation, crests must be checked and, if necessary, corrected by one of the several available techniques.

Alveolar Ridge Augmentation↗

Rationale for socket preservation after extraction of a single-rooted tooth when planning for future implant placement.

After tooth extraction, the alveolar ridge will commonly decrease in volume and change morphologically. These changes are usually clinically significant and can make placement of a conventional bridge or an implant-supported crown difficult. If bone resorption is significant enough, then placement of an implant may become extremely challenging. Postextraction maintenance of the alveolar ridge minimizes residual ridge resorption and, thus, allows placement of an implant that satisfies esthetic and functional criteria. Recent advances in bone grafting materials and techniques allow the dentist to place implants in sites that were considered compromised in the past. This article focuses on the healing pattern of sockets, with and without the use of regenerative materials, and the rationale for preserving the dimensions of the extraction socket. Histologic and clinical evidence is reviewed to provide an in-depth understanding of the logic behind and value of socket preservation.

Alveolar Bone Loss↗

Pattern of dental extraction in children in a Nigerian tertiary hospital.

Changes that occurred in the pattern of tooth extraction in the last 13 years among a population of children in Nigerian were studied. The result of this study was then compared to that of a past study done in the same institution 13 years earlier. Information on age, gender, and indication of tooth extraction was collected prospectively from 379 consecutive patients who visited the outpatient Pediatric Dental Clinic for the first time during the year 2002. Results showed tooth extraction due to caries decreased, while there was an increase in tooth extraction from an apparent increase in orthodontic treatment needs. Acute necrotizing ulcerative gingivitis (ANUG), a significant cause of tooth loss in the last decade, decreased significantly. The pattern of deciduous tooth loss also changed as more anterior teeth were lost for orthodontic reasons in this present study. The pattern of tooth loss in the permanent dentition remains very similar to that of the past study, though more premolars were lost in the present study. There appears to be an increasing need for tooth extractions in orthodontic treatment for this population of children. The focus of planned dental health care provisions, treatment policies, and training emphasis in child dental care may need to shift to addressing orthodontic needs.

Adolescent↗

Extraction defect assessment, classification, and management.

Tooth extraction is a traumatic procedure initiating a complex cascade of biochemical and histologic events that inevitably lead to a reduction of alveolar bone and soft tissue. These tissue alterations often lead to an esthetic compromise of the future implant restoration. The hard- and soft-tissue architecture surrounding the extraction defect largely dictates the course of dental implant treatment. The EDS or extraction-defect sounding classification is a novel system introduced to simplify the decision-making process when planning for dental implant therapy following tooth extraction. Dental implant treatment guidelines based on the EDS classification are discussed. A review of pretreatment evaluations necessary to prepare for esthetic implant procedures is also presented.

Alveolar Bone Loss↗

The effect of premolar extractions on tooth size discrepancies.

The purpose of this study is to investigate the effect of premolar extractions on tooth size discrepancy. A total of 213 plaster casts were divided into a Bolton big (BB), a Bolton normal (BN) and a Bolton small (BS) group according to the Bolton normal value plus or minus one standard deviation. The Bolton overall ratio of each group was measured and compared before and after hypothetical premolar extractions. The Bolton overall ratios after premolar extractions were smaller than those before extraction in each group. Some of the patients in the BN group and BB group were moved into the BS group and BN group after premolar extractions. A tooth size discrepancy occurred in some patients with normal overall ratios after premolar extractions, but a tooth size discrepancy might be corrected in some patients with big overall ratios after premolar extraction.

Adolescent↗

Flow rate, sodium and potassium concentration in mixed saliva of complete denture-wearers.

Flow rate, sodium and potassium concentrations in stimulated mixed saliva obtained from eleven elderly (mean age 63) inexperienced denture-wearers, were determined. Salivary samples were collected at four different dental stages: 1. Before tooth extraction. 2. After tooth extraction. 3. Three weeks after wearing newly constructed complete dentures. 4. Following one year of denture wearing. Plasma electrolytes were included for comparison. The salivary sodium and potassium concentrations varied from stage to stage without showing corresponding variations in sodium and potassium in the blood. This points to selective action and an active transport system in the salivary cells. The mean flow rate and salivary electrolyte concentration showed a definite significant rise following the wearing of new complete dentures as compared with the previous dentulous and edentulous stages (Period A, non-denture-wearers). The mean flow rate was 2 ml/min after denture-wearing compared to 0.75 ml/min at the dentulous and edentulous stage (Period A). The stimulant effect represented by the dentures was found to be even more pronounced after one year. Mean sodium and potassium concentration at Period A were at levels of 5.50 and 13.67 mequiv./l respectively, as compared to levels of 23.72 and 19.40 mequiv./l respectively, after insertion of dentures. The difference was significant at a level of P less than 0.005. Although sodium concentration correlated well with flow rate, potassium concentration did not show any correlation with variations during secretion, following the wearing of dentures.

Adult↗

Current perspectives in residual ridge remodeling and its clinical implications: a review.

PURPOSE: This article reviews the current understanding of the biology of tooth extraction wound healing and residual ridge remodeling. METHODS: The review of the biology of tooth extraction wound healing involves a discussion of the different cells populating the tooth extraction wound, the matrix formation, and the control of the repair process in the short-term. Defects in socket matrix formation or cellular activity will lead to stalled healing. The review of residual ridge remodeling describes the long-term result of tooth extraction and formation of residual ridges, in which the quantity of bone tissue continuously decreases. This may suggest that any potential regulatory factors of residual ridge resorption should have an adverse effect either on the increased catabolic activity by osteoclasts or on the decreased anabolic activity by osteoblasts. Both short-term tooth extraction healing and long-term residual ridge remodeling processes are interdependent. Furthermore, any potential genetic and environmental regulatory factors can affect the quality and quantity of bone by altering the gene expression events taking place in bone cells. RESULTS: The intent of this article was to review the current progresses of biologic research on residual ridge remodeling and to relate the changes at molecular, cellular, and tissue levels. The understanding of residual ridge remodeling may provide a sound scientific basis for improved restorative and therapeutic treatments of the edentulous population.

Alveolar Process↗

Health services research in oral health care: an empirical example.

Health services research is mainly applied research which can contribute to the production of knowledge necessary to appropriate decisions in health care. As an example, a study of the occurrence of tooth extractions is presented. Two hypotheses were tested: a negative relationship between provider density and consumer income, and the probability of tooth extractions and the number of teeth extracted, conditional upon extraction. A nationwide sample of 1286 non-institutionalized Norwegians 20 yr and above was interviewed by a public survey institute. The data were analyzed using a two-part model including logistic regression and multiple regression analysis. One third of the sample had had a tooth extraction during the last 5 yr. The majority of the sample had few teeth extracted at the time of extraction. The probability of tooth extraction was related to provider density and not to consumer income. The number of teeth extracted was related neither to provider density nor to income. Tooth extraction was not related to age. Some policy implications are discussed.

Adult↗

Periodontal treatment decisions for molars: an analysis of influencing factors and long-term outcome.

BACKGROUND: The purpose of this retrospective study was 1) to analyze factors influencing the treatment decision for periodontitis-affected molars and 2) to evaluate the long-term outcome of the decision. The treatment alternatives included in the analysis were maintenance of the tooth with only non-surgically/surgically performed scaling/root planing with or without furcation plasty, root separation/resection, and tooth extraction. METHODS: Data collected from a total of 1,313 first and second molars in 222 patients (mean age 45 years; range 14 to 73 years), referred for periodontal treatment, were analyzed with respect to treatment decisions for furcation-involved teeth. The patients had been examined with respect to oral hygiene status, gingival conditions, probing depth, furcation involvement, and radiographic bone height before and after active periodontal treatment. Frequencies, mean values and standard deviations were calculated for the various variables assessed. Multiple regression models were formulated in order to analyze the influence of various variables on treatment decisions. One-hundred and sixty (72%) of the patients agreed to participate in a follow-up examination to determine the clinical and radiographic status of the molars 8 to 12 years after the active phase of treatment for evaluation of the long-term outcome of the treatment decision. RESULTS: Twenty-eight percent of the molars were extracted and 4% were root separated/resected. Factors found to significantly influence the decision of tooth extraction were tooth mobility, tooth position, lack of occlusal antagonism, degree of furcation involvement, and remaining bone support. Of the factors analyzed with respect to root separation/resection, molar position and degree of furcation involvement showed the strongest influence on the treatment decision. The 8- to 12-year follow-up examination revealed that 96% of the molars subjected to non-resective therapy were still in function. The corresponding figure for root separated/resected molars was 89%. Loss of radiographic bone support during the 10-year follow-up period was 0.1 to 0.6 mm for the various molars with the highest value for maxillary second molars. CONCLUSIONS: A conservative approach to the treatment of molars with even deep furcation invasions may show a high long-term success rate, provided maintenance care is offered.

Adolescent↗

Bacteremia of dental origin and antimicrobial sensitivity following oral surgical procedures in children.

METHODS: The prevalence and intensity of bacteremia of dental origin were examined in 207 children divided into four groups: a baseline with no surgical intervention (group I), after a single tooth extraction (group II), multiple tooth extraction (group III), and mucoperiosteal flap elevation (group IV). The bacterial isolates were grown using a broth culture (Bactec) and lysis centrifugation (Paediatric Isolator) techniques. Dental plaque deposits, gingivitis, spontaneous gingival bleeding and the presence/absence of a dental abscess were recorded and their relationship to bacteremia assessed. RESULTS: The broth culture was positive for group I 11% of the time, group II for 43%, group III for 54%, and group IV for 43%. The Paediatric Isolator system was found to be a poor method for detecting bacteremia, having only one quarter the sensitivity of the broth culture technique. When organisms were isolated, the intensity of bacteremia ranged from 1 to 3400 colony forming units per milliliter (cfu/mL). Bacterial isolates were susceptible to most of the antibiotics recommended for antibiotic prophylaxis, but erythromycin, gentamycin, penicillin G, and teicoplanin were only 80% (or less) effective in their efficacy while chlorhexidine, amoxicillin, clindamycin, and vancomycin were between 92 and 100% effective. CONCLUSIONS: The antibiotics commonly used for an oral and/or parenteral prophylaxis are likely to be effective on at least 80% of occasions with most of them effective on 100% of occasions.

Amoxicillin↗

Deep impacted mandibular second molar: a case report.

Impaction of mandibular second molars is relatively rare. A case of a deep impacted mandibular right permanent second molar in a 26-year-old woman is presented. This article describes the extraction of the tooth and reports the risks of the surgical procedure. Careful manipulation of tissues and correct application of mechanical principles involved in tooth extractions allowed surgical success.

Adult↗

Principles and implications of site preservation for alveolar ridge development.

The extraction of a tooth normally results in the loss of ridge height and width. Often, clinicians are faced with the management of edentulous sites that are less than optimal for prosthetic rehabilitation and implant restoration due to considerable alveolar ridge collapse after tooth removal. Site preservation using bone grafts or substitutes with and without a membrane maintain ridge dimensions and contours. However, some clinicians believe that such procedures are over-treatment. This paper reviews the concepts and indications for site preservation following tooth extraction for the purpose of facilitating implant placement and conventional prosthetic restoration.

Alveolar Bone Loss↗

Factors associated with implant recommendation for single-tooth replacement.

The use of dental implants for single-tooth replacement has been established as a predictable treatment option; yet, limited data are available as to how frequently this option is recommended to patients. The aim of the present study was to examine the frequency of implant recommendation by general dental practitioners after single-tooth extraction and factors influencing their decision to recommend an implant. All single-tooth extractions performed in 26 general dental practice clinics in Kuwait over a 30-day period were examined. Dentists in these centers used the study form to record demographic data, the type of tooth extracted, reason for extraction, and replacement options presented to the patients. Univariate and logistic regression analyses were used to examine associations between background factors and decisions to recommend implant therapy. A total of 1367 patients (mean age, 37.9 +/- 11.8 years) had an extraction of one tooth during the study period. Forty-three patients were offered implants as a replacement option (3.3% of the total sample; 8.6% of patients who were offered tooth replacement options). Factors associated significantly with the recommendation of an implant by Kuwaiti dentists to their patients included younger age, regular dental maintenance visits, and adequate oral hygiene practices (P < 0.05; binary logistic regression). Dental implant recommendation for single-tooth replacement in the present sample of dentists was low. Factors associated significantly with dentist recommendation of an implant for single-tooth replacement included age, history of dental maintenance, and oral hygiene practices.

Adolescent↗

Influence of bioactive glass on changes in alveolar process dimensions after exodontia.

BACKGROUND: Preservation of the alveolar process after tooth extraction is desirable because it facilitates placement of endosseous implants and minimizes adverse esthetic results associated with fixed partial dentures. The purpose of this study was to evaluate the clinical effectiveness of bioactive glass used as a graft material combined with calcium sulfate used in the form of a mechanical barrier in preserving alveolar ridges after tooth extraction. METHODS: Sixteen patients who required extraction of 2 anterior teeth or bicuspids participated in the study (split mouth design). After tooth extraction and elevation of a buccal full-thickness flap, experimental sockets were filled with bioactive glass, which in turn was covered with a layer of calcium sulfate. Control sites did not receive any graft or calcium sulfate. Titanium pins served as fixed reference points for measurements. No attempt was made to advance the flap to cover the socket areas on control or experimental sites (open socket approach). Reentry surgeries were performed at 6 months. RESULTS: Reentry surgeries showed that experimental sites presented with (1) significantly more internal socket bone fill (6.43 +/- 2.78 mm vs 4.00 +/- 2.33 mm on control sites), (2) less (although not statistically significantly less) resorption of alveolar bone height (0.38 +/- 3.18 mm vs 1.00 +/- 2. 25 mm on control sites), and (3) similar degree of horizontal resorption of the alveolar bony ridge as compared with controls (3. 48 +/- 2.68 mm vs 3.06 +/- 2.41 mm on control sites). CONCLUSIONS: This study suggests that treatment of extraction sockets with a combination of bioactive glass and calcium sulfate is of some benefit in preserving alveolar ridge dimensions after tooth extraction.

Adult↗

Reasons for extraction of permanent teeth in Japan.

Eight hundred forty-nine Japanese dentists were asked to record the reason for every tooth extraction of permanent teeth during 1 week in each of four seasons. The reasons were assigned to six groups: dental caries, periodontal disease, eruption problems, trauma, orthodontics and other reasons. Thirty-eight to 40% of the dentists returned the forms in each season, relating to a total of 11,175 extracted teeth. Overall, caries was the most frequent reason for tooth extraction (55.4%), followed by periodontal disease (38.0%). The females lost more teeth due to caries than did the males. In the > or = 16 age groups, caries was the main reason for tooth extraction. However, periodontal disease became principal only in the males aged 46-65 yr. Anterior teeth, especially in the mandible, represented the highest percentage of periodontal extractions. A considerable difference in the major reason for maxillary tooth loss was observed between both sexes. Maxillary premolars and molars in the males were extracted for periodontal disease as much as for caries, whereas caries was the predominant reason for loss of all maxillary teeth in the females.

Adolescent↗

Permanent sensory nerve impairment following third molar surgery: a prospective study.

OBJECTIVE: This prospective study reports the proportion of permanent sensory impairment of the inferior alveolar and lingual nerves and the factors influencing such prevalence after the removal of mandibular third molars under local anesthesia. STUDY DESIGN: There were 1,087 patients with 1,087 mandibular third molars removed under local anesthesia from 1998 to 2003. Standardized data collection included the patient's name, age, gender, radiographic position of extracted tooth, grade of surgeon, proximity of the inferior alveolar nerve, and the prevalence of lingual and/or inferior alveolar nerve paresthesia. RESULTS: Inferior alveolar nerve injury was 4.1% 1 week after surgery and decreased to 0.7% after 2 years of follow-up, and alteration in tongue sensation occurred in 6.5% of patients 1 week after surgery and decreased to 1.0% after 2 years of follow-up. CONCLUSION: The experience of the operator was found to be a significant factor in determining both permanent lingual nerve (P=.022) and permanent inferior alveolar nerve paresthesia (P=.026).

Adolescent↗

Human periodontal ligament fibroblast response to PDGF-BB and IGF-1 application on tetracycline HCI conditioned root surfaces.

The purpose of this study was to investigate the effect of 2 growth factors, platelet-derived growth factor-BB (PDGF-BB) and insulin-like growth factor-1 (IGF-1), alone or in combination, on the adherence of human periodontal ligament fibroblast (PDL) to tetracycline HCl (TTC) conditioned and nonconditioned periodontally involved root surfaces. There were 80 root dentine chips from 80 patients, ranging from 35 to 70 years of age, each with one periodontally involved tooth requiring extraction. A root dentine chip was obtained from the subgingival surface opposite to the periodontal pocket of each extracted tooth. The dentine chips were randomly distributed into one of 8 groups. In group 1, PDL fibroblasts were cultured and allowed to attach on the dentine surface. In group 2, PDL fibroblasts were cultured on a PDGF-BB pre-treated dentine surface and in group 3, they were cultured on a IGF-1 pre-treated dentine surface. In group 4, PDL fibroblasts were cultured on a dentine surface pretreated with a combination of PDGF-BB and IGF-1. In group 5, PDL fibroblasts were cultured and allowed to attach on the TTC conditioned dentine surfaces. In groups 6 and 7, surface of dentine chips were conditioned with TTC and then were treated with PDGF-BB or IGF-1 respectively, followed by placement of PDL fibroblast and cultured. In group 8, dentine surfaces were conditioned with TTC and then pre-treated with a combination of PDGF-BB and IGF-1 before the fibroblasts were cultured. After 24 h of incubation, the media was removed and samples were fixed and processed for SEM at magnifications of x34, x750, x2000. Photographing and evaluation of samples was performed at x750 in which fibroblast adherence was measured by counting cells within a standard test area. The results of the non-TTC conditioned root surfaces demonstrated a significant increase in fibroblasts adherence in the PDGF-BB and combination PDGF-BB/IGF-I treatment groups (groups 2, 4) when compared to the control (group 1) as well as the TTC control (group 5). The combination of PDGF-BB/IGF-1 (group 4) did not significantly improve the adhesion of cells compared to PDGF-BB alone (group 2), but did significantly improve adhesion when compared to IGF-1 alone (group 3). There were no significant differences in cell morphology between the growth factor groups (groups 2, 3, 4) and control (group 1). In general, the cells demonstrated a flat, stellate-shaped morphology. The results of the TTC conditioned root surfaces, showed a statistically significant increase of cellular adherence in the PDGF-BB group (group 6) when compared to the TTC control (group 5), similar to the non-TTC group (group 2). However, the morphology of the cells in groups 5, 6, 7, and 8 demonstrated generally a rounded or oval shape with only an occasional cell exhibiting a flat form. In the experimental system of this study, the inclusion of PDGF-BB on the surface of dentine chips increased the number of adhering PDL cells, and the addition of TTC conditioning had little effect except to change the morphology of adhering cells.

Adult↗