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Temporary aneurysm orifice balloon occlusion as an alternative to retrograde suction decompression for giant paraclinoid internal carotid artery aneurysms: technical note.

OBJECTIVE: Giant paraclinoid carotid artery aneurysms frequently require the temporary interruption of local circulation to facilitate safe clip occlusion. Owing to the brisk retrograde blood flow through the ophthalmic artery and cavernous branches, the simple trapping of the aneurysm by cervical internal carotid artery clamping and intracranial distal clipping may not adequately soften the lesion. Retrograde suction decompression aspiration of this collateral supply by a catheter introduced into the cervical internal carotid artery is a popular method to achieve aneurysm deflation. With a large collateral supply, the method is not effective enough. The advent of relatively long and maneuverable soft balloons allows temporary occlusion of the aneurysm orifice. METHODS: We applied this method in two instances of giant carotid ophthalmic aneurysms. In both instances, a 15- to 20-mm-long and 4-mm-wide occlusion balloon was inserted in the internal carotid artery at the level of the aneurysm before craniotomy. After craniotomy and dissection of the aneurysm neck, the balloon was inflated under intraoperative angiographic control. RESULTS: The aneurysm became soft enough in both cases without tapping and aspiration to allow safe clip occlusion. In the first case, the postoperative course was uneventful and visual acuity improved. A known additional infraclinoid part of the aneurysm was eliminated endovascularly 5 months later using balloon-protected injection of vinyl alcohol copolymer (Onyx; Micro Therapeutics, Inc., Irvine, CA). In the second case, a postoperative symptomatic vasospasm developed 15 hours after surgery. Hypertensive therapy resulted in the disappearance of symptoms and an otherwise uneventful course with improvement of vision. CONCLUSION: This preliminary experience suggests that this new method is a feasible alternative to retrograde suction decompression.

Balloon Occlusion↗

Cytoskeleton and pericellular matrix organization of pure adult human keratinocytes cultured from suction-blister roof epidermis.

Pure adult human keratinocyte cultures were raised from suction-blister roof epidermis and cultured in MCDB-151 medium. In primary culture the epidermal cells rapidly adhered, spread and began to proliferate on collagen-coated growth substrata but not on uncoated plastic or glass substrata. A fibrillar keratin-specific fluorescence, showing a typical cell-cell arrangement, was seen in all cells in indirect immunofluorescence microscopy, whereas only some cells also showed vimentin-specific staining. A fine fibrillar fibronectin-specific surface staining was seen at the margin of attaching cells and in marginal cells of spreading cell islands, whereas no fluorescence could be seen in epidermal cells, with antibodies against type IV collagen or laminin. Interestingly, the marginal cells also showed intracellular fibronectin. The synthesis of fibronectin in epidermal cell cultures could also be revealed by metabolic labelling experiments with [35S]methionine. In contrast to primary cultures, subcultivated keratinocytes also adhered to uncoated plastic and glass substrata. After subcultivation, keratin and surface fibronectin distribution remained unaltered but after some subcultivations, most of the cells also showed fibrillar vimentin and expressed fibronectin intracellularly. The results show that the suction-blister method provides an easy way to obtain pure epidermal cell cultures without contaminating mesenchymal cells. Our results also suggest a direct role for fibronectin but not for collagen type IV or laminin in adhesion and spreading of epidermal cells in vitro.

Adolescent↗

Use of sonomicrometry demonstrates the link between prey capture kinematics and suction pressure in largemouth bass.

Suction feeding in fishes is the result of a highly coordinated explosive expansion of the buccal cavity that results in a rapid drop in pressure. Prey are drawn into the mouth by a flow of water that is generated by this expansion. At a gross level it is clear that the expansion of the buccal cavity is responsible for the drop in pressure. However, attempts using high-speed video recordings to demonstrate a tight link between prey capture kinematics and suction pressure have met with limited success. In a study with largemouth bass Micropterus salmoides, we adopted a new technique for studying kinematics, sonomicrometry, to transduce the movement of skeletal elements of the head during feeding, and synchronized pressure recordings at a sampling rate of 500 Hz. From the positional relationships of six piezoelectric crystals we monitored the internal movements of the buccal cavity and mouth in both mid-sagittal and transverse planes. We found that peak subambient pressure was reached very early in the kinematic expansion of the buccal cavity, occurring at the time when the rate of percentage change in buccal volume was at its peak. Using multiple regression analyses we were consistently able to account for over 90%, and in the best model 99%, of the variation in buccal pressure among strikes using kinematic variables. Sonomicrometry shows great promise as a method for documenting movements of biological structures that are not clearly visible in the external view provided by film and video recordings.

Animals↗

Circulation of blood and viability after blunt suction lipectomy in pig buttock flaps.

Bilateral buttock flaps were raised in 13 Yorkshire pigs, and the viability and superficial blood flow were assessed by injection of fluorescein and laser Doppler flowmetry. One flap was then chosen at random from each pig to be defatted by blunt suction lipectomy. The opposite flap served as the control. Five and 30 minutes after lipectomy, the experimental flaps showed a 31% and 37% decrease in laser Doppler values (p < 0.05 and p < 0.01, respectively), measured 6 cm proximal to the margin of the fluorescein dye. There was no reduction in the values in the controls. One week after liposuction, the median area of flap necrosis in treated flaps was 4,615 mm2 (range 735-6,748) and in controls 4,104 mm (1,576-5,879). This difference was not significant (p = 0.24). Blunt suction lipectomy of the skin flaps did not significantly decrease the viability. The decreased skin circulation shown by laser Doppler soon after lipectomy may be a minor or temporary phenomenon.

Animals↗

Retrograde suction decompression of giant paraclinoidal aneurysms. Technical note.

Giant paraclinoidal carotid artery aneurysms frequently require temporary interruption of local circulation to facilitate safe occlusion. Due to brisk retrograde flow through the ophthalmic artery and cavernous branches, simple trapping of the aneurysm by cervical internal carotid artery clamping and intracranial distal clipping may not adequately soften the lesion. The authors describe a retrograde suction method of aspiration of this collateral supply which they have used in over 40 cases. After temporary trapping, a No. 18 angiocatheter is inserted into the cervical internal carotid artery. This catheter is then connected to a wall suction point allowing rapid aneurysm deflation. This technique, accomplished by the surgical assistant, permits the surgeon the freedom to use both hands in dealing quickly with the aneurysm.

Carotid Artery Diseases↗

Suction curettage: therapeutic effectiveness in dysfunctional uterine bleeding.

A group of 60 patients between the ages of 30 and 45 were randomly selected to have either a suction curettage or dilatation and curettage. The criteria used for patient selection was that they had dysfunctional uterine bleeding, a normal gynecologic examination, and were receiving no hormonal therapy. These patients were followed up for at least 3 months. Although the number of patients is relatively small, the results showed that, therapeutically, suction curettage was equal to dilatation and curettage in alleviating dysfunctional uterine bleeding.

Adult↗

New classification of histochemical staining patterns of acetylcholinesterase activity in rectal suction biopsy in Hirschsprung's disease.

Several previous studies have introduced classifications of Acetylcholinesterase (AChE) histochemical staining patterns in rectal suction biopsy performed in patients with Hirschsprung's disease. However, we introduce a new classification that is less complicated but shows the same age dependence as seen in previous studies. 135 rectal suction biopsies were submitted to histochemical staining for AChE activity and 88 specimens showed increased AChE activity. Therefore, we retrospectively analysed these 88 cases and could establish three patterns. Pattern I, presence of thick nerve trunks or coarse nerve fibers only in the muscularis mucosae and submucosa. This pattern was mainly seen in children aged 6 months or below. Pattern II, presence of abundant nerve fibers in all three layers of mucosa. This pattern was predominantly seen in children over 6 months of age. Pattern III, not predominant in any age group, showed positive nerve fibers in all three layers but, in one or more layers, the nerve fibers were sparse. Upon comparison with previous studies, we could observe the same age-pattern relationship. Thus, we propose this method of classification as a new tool to classify AChE histochemical staining patterns.

Acetylcholinesterase↗

Comparison of hemodynamic and volume responses to different levels of lower body suction and head-up tilt.

Orthostatic challenge such as lower body suction (LBNP) or head-up tilt (HUT) induces marked shifts of blood from the cardiopulmonary into lower extremity vascular compartments. As a reaction to central hypovolemia, counterregulating mechanisms take place immediately, including central/peripheral circulatory responses and neurohumoral responses. Compensatory answers are exerted via autonomic reflexes, ie, cardiopulmonary and arterial baroreceptor mechanisms. The sympathetic nervous system increases heart rate and peripheral resistance to adjust the cardiovascular system to the stress situation. The physiological response to head-up tilt and LBNP are similar but not identical. Numerous investigations on cardiovascular changes during tilt and LBNP have been performed, but the data vary greatly because of different experimental protocols. Musgrave et al. have done systematic comparisons of the overall hemodynamic responses to these two stress stimuli in the same subjects. To our knowledge, no systematic comparative study of effects of LBNP and HUT of different magnitude, using identical subjects, has yet been performed. This study investigates two different grades of lower body suction and two tilt angles in 12 subjects. Before, during and after cardiovascular loading we recorded heart rate (HR), systolic (SBP), diastolic (DSP) and mean arterial blood pressure (MAP). For calculation of blood volume shifts, plasma density (PD) and hematocrit (Ht) was measured. We addressed the questions if 1) heart rate and blood pressure react similarly to LBNP and HUT, 2) there is evidence for unloading of high pressure receptors with low levels of orthostatic / circulatory stress, and 3) a correlation between amount of fluid loss and grade of stimulus intensity can be established.

Blood Pressure↗

Treatment of vitiligo with autologous epidermal transplantation using the roofs of suction blisters.

We report our experience of autologous epidermal transplantation for three patients with vitiligo. The vitiligo in two patients was stable whereas that in the third was active. Autologous epidermal transplantation using suction blister roofs from normally pigmented skin was performed following the failure to repigment skin using topical steroid and/or psoralen-ultraviolet A treatment. Grafts were well taken in all three patients. Satisfactory repigmentation was noted in the two patients who had stable vitiligo; there were no complications except for mild hyperpigmentation at the donor areas. For the patient who had active vitiligo, depigmentation of the graft and concomitant Koebner's phenomenon at the donor site were observed 3 weeks after the procedure. We conclude that autologous epidermal transplantation using the roofs of suction blisters is an excellent and safe repigmenting procedure for stable, localised vitiligo and that active disease precludes transplantation.

Journal Article↗

Endogenous Candida endophthalmitis after two consecutive procedures of suction dilatation and curettage.

Endogenous Candida endophthalmitis (ECE) is a rare disease. We present a patient with Candida endophthalmitis after two consecutive procedures of suction dilatation and curettage for elective abortion. A 24-year-old single woman who received a suction dilatation and curettage one week ago developed pain and blurred vision in the right eye. Endogenous Candida endophthalmitis was diagnosed and treated with oral fluconazole and pars plana vitrectomy with adjunction of intravitreal amphotericin B injection. The vitreous culture revealed Candida albicans. The vitreous inflammation subsided greatly after the initial treatment but flared up after the second dilatation and curettage for incomplete abortion 5 days after the vitrectomy. The oral fluconazole was replaced by intravenous amphotericin B, and a second vitrectomy with injection of intravitreal amphotericin B was performed. Postoperatively, the intraocular inflammation resolved gradually. Six months after the second vitrectomy, the best-corrected visual acuity in the right eye was 20/25. The excellent visual acuity of this patient was attributed to the early diagnosis and aggressive treatment. For patients with mild disease, less toxic oral fluconazole as the systemic antifungal agent instead of more toxic intravenous amphotericin B has been recommended. For those with advanced disease, intravitreal amphotericin B in conjunction with vitrectomy has been advocated by many eye surgeons.

Adult↗

[The therapeutic significance of bronchial suction-drainage in infants].

Bronchial suction-drainage in infants--according to our observations--is a life-saving procedure in cases of aspiration, severe bronchitis and retention of bronchial secretion. It can also be very effective in atelectasis, bronchopneumonia and pulmonary abscess. The earlier the drainage the quicker the clearing up of the atelectasis. An additional indication for performing bronchial suction in severe lower respiratory tract infections is to gagain secretion for bacterial culture. This is especially important in the Gram negative and Staphylococcus infections of young infants. The right upper pulmonary lobe is the most common localisation for atelectasis and pneumonia in this age group. One possible explanation for this could be that malformed bronchi are more frequently found in the right than in the left upper lobe. It is such a characteristical phenomenon in infancy that we called it "the right upper lobe syndrome".

Bronchi↗

Effect of floc size and structure on biosolids capillary suction time.

Both size and structure of wastewater solids (biosolids) have been hypothesised to have an impact on the dewaterability of these solids yet very little data exists to validate this hypothesis or to elucidate the relative effects of size and structure. We have recently undertaken studies in which the size and structure of activated sludge flocs were altered in a controlled manner and the dewaterability of resultant flocs examined using the well established capillary suction time (CST) test. A small angle light scattering method was applied for the determination of activated sludge floc size and structure. The results obtained in this work show that floc structure is a major determinant of capillary suction time. In some instances, flocs have almost double the median (D(4,3)) size but possess similar fractal dimensions and similar CST values.

Bacteria↗

Outcome of rubber band ligation of haemorrhoids using suction ligator.

BACKGROUND: Haemorrhoids are a common surgical problem seen in the outpatient department. Rubber band ligation using suction is an effective treatment for symptomatic haemorrhoids but associated with significant morbidity. This prospective observational study was carried out to assess the efficacy, effectiveness and complications of rubber band ligation performed in outpatient for symptomatic haemorhoids using suction ligator. The results and outcome of procedure performed by the consultants and senior residents were also compared. METHODS: 56 consecutive patients with symptomatic haemorrhoids underwent rubber band ligation in the outpatient clinic of the department of general surgery, Pakistan Institute of Medical Sciences. Outcome measures were symptomatic cure i.e. stoppage of bleeding and reduced mucosal prolapse. Complications were categorized as immediate, early (within one week) and late (within 3 months). RESULTS: Symptomatic cure was achieved in 50(89.20%) patients (stoppage of bleeding and reduced mucosal prolapse). Six (10.72%) patients required further banding. Pain (mild to severe) was most common immediate and intermediate complication (14 and 20 patient's respectively). CONCLUSION: Rubber band ligation is an effective, outdoor procedure for symptomatic haemorrhoids, but associated with certain degree of morbidity.

Adult↗

[Suction cup ocular pressure versus Vörösmarthy oculopression. Biometry differences].

In a 20-min follow-up after oculopression, biometric measurements were taken before, immediately after, and 5, 10, 15 and 20 min after finishing oculopression. Thirty-two eyes were measured by ultrasound using the immersion technique with a 10 MHz A-scan probe. Sixteen cataract patients more than 50 years of age and 16 healthy young subjects up to 30 years of age took part in the study. Oculopression was performed either with a Honan Oculopressor or with a Mikuni and Yoneyama suction-cup oculodynamometer. The anterior chamber depth showed higher initial deepening following Honan oculopression, whereas the length of the vitreous was found to be shorter with the same method. Suction-cup oculopression revealed no distinct changes in these compartments. Nevertheless, 10 min after oculopression, there was no statistically significant difference between the two oculopression techniques. When comparing the age groups, the cataract patients showed more express change than the younger subjects.

Adult↗

[Does the suction biting of uninfected ixodid ticks protect against tick-born encephalitis in subsequent bites?].

It has been experimentally established that suction of noninfected preimago and imago of Ixodoidea to sensitive animals (e.g. white mice) does not lead to the elaboration of immunity protection from bites of insects infected with tick-borne encephalitis virus. A protecting effect may be manifested in decreased likelihood (incidence) of repeated suction to animals formerly bitten by ticks.

Animals↗

Suction-assisted lipectomy--an adjunct to orthopaedic treatment.

Suction-assisted lipectomy was first performed in 1964 but did not become popular until 1981. Many thousands of patients are now so treated for cosmetic reasons each year, but no previous use of this technique as an adjunct to orthopaedic treatment has been reported. Two patients were successfully treated by suction-assisted lipectomy to reduce the circumferential measurement and shape of the residual limb so that prosthetic restoration could be more easily performed.

Adolescent↗

[Electrocoagulation of the His bundle node junction in dogs by a high-frequency current delivered by suction catheter].

High-frequency currents constitute an attractive form of energy for transcutaneous myocardial destruction, but their potential for creating lesions varies with the nature of contact between electrode and skin. The adequacy of a suction catheter for electrocoagulation of the AV node-His bundle junction was assessed in 7 dogs. The high-frequency current (1.2 MHz) was delivered as bursts of 6 watts lasting 30 seconds, between the distal electrode of a bipolar catheter containing a central lumen (USCI 8F) and a wide skin electrode. During firing, an 80 kPa depression was applied to the lumen. Electrophysiological testing was performed before and immediately after firing. Continuous 24-hour Holter recording was carried out before, immediately after, then between the 2nd and 20th days post-firing. Following another electrophysiological study, the animals were killed on the 15th or 21st day for anatomical study. Complete atrioventricular block was obtained in all dogs during the first (n = 4) or second (n = 3) firing and persisted in 6 dogs up to the time of anatomical study. The atrial and right ventricular electrophysiological parameters remained unmodified after firing, and no severe ventricular arrhythmia was recorded during the study. The histological lesions were 4.7 +/- 0.7 mm in mean diameter and 3.1 +/- 0.6 mm in mean depth. It is concluded that electrocoagulation of the AV node-His bundle junction performed with high-frequency currents is a safe and selective technique. Using suction catheters makes this technique well reproducible with moderate amounts of energy. The development of preformed catheters should reduce the duration of the procedure.

Animals↗