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PubMed2002

Task switching deficits associated with Parkinson's disease reflect depleted attentional resources.

Using a Stroop task switching paradigm, Brown and Marsden [Brain 111 (1988) 323; Brain 114 (1991) 215] proposed that set shifting deficits in Parkinson's disease (PD) reflect limited attentional resources rather than deficits in internal control, as was previously supposed. In the present study, we tested this claim using a more recently developed Stroop task switching paradigm for which the internal control and attentional resources accounts made contrasting predictions. A PD group (N=30) was compared with an age-matched control group (N=34) on vocal response time (RT) for color naming and word reading in response to neutral and incongruent Stroop stimuli. Participants carried out four blocks of task repetition trials, and eight blocks of task switching trials. The results revealed that a deficit due to PD was absent for two conditions necessitating internal control, but was present in the condition which placed the highest demand on attentional resources. This selective deficit is congruent with Brown and Marsden's conclusions that depleted attentional resources, not an impairment in internal control per se, is the basis of the set shifting deficits associated with PD.

Aged↗

PubMed2003

Phytoplankton, pelagic community and nutrients in a deep oligotrophic alpine lake: ratios as sensitive indicators of the use of P-resources (DRP:DOP:PP and TN:TP:SRSi).

The different use of P-resources between two sites in the deep oligotrophic Traunsee was studied by seasonal and vertical patterns of phytoplankton and nutrients from 12/1997 to 10/1998. The P-resources were evaluated from the proportion between the P-fractions, the dissolved reactive P (DRP), dissolved non-reactive P (DOP) and particulate organic P (PP) and from the stoichiometry between nutrients, the total N (TN), the total P (TP) and soluble reactive Si (SRSi). Significant differences between an inshore site impacted by industrial tailings (Ebensee Bay, EB) and an open water reference site (Viechtau, VI) were evident from vertical profiles of both the P-accumulation (%PP of TP) evaluated by DRP:DOP:PP and the distribution of phytoplankton assessed by Si-exhaustion (TN:TP:SRSi), but not from the seasonal patterns of phytoplankton composition, S:V ratios of the algal community or surface layer nutrient dynamics. Low TP and the stable stratification from May to September triggered the relative accumulation of epilimnetic P at VI as it was evident from both the higher portion of particulate P within TP (%PP of TP) and from the shift towards P-enrichment in nutrient stoichiometry of TN:TP:SRSi. The predominance of around 55-52% algal carbon over bacteria at the surface layer to 20m coincided spatially with the lowest Si content relative to N and P. The disturbances at the impacted site was summarised by: up to 11% less P accumulation by organisms at the surface, no stoichiometric shift towards TP in the epilimnion when compared with deeper layers and a reduction of the trophogenic zone to the top 10m. Reasons for this disturbance are seen in the unstable stratification, turbidity, higher TP and the metazoan dominated food chain. Both triple ratios, DRP:DOP:PP and TN:TP:SRSi, were sensitive indicators of the use of P-resources by plankton communities, while inorganic dissolved fractions (DIN:DRP:SRSi, DIN = dissolved inorganic N) provided only insufficient information on nutrient resources in Traunsee.

Environmental Monitoring↗

PubMed2004

Responding to the global human resources crisis.

The global community is in the midst of a growing response to health crises in developing countries, which is focused on mobilising financial resources and increasing access to essential medicines. However, the response has yet to tackle the most important aspect of health-care systems--the people that make them work. Human resources for health--the personnel that deliver public-health, clinical, and environmental services--are in disarray and decline in much of the developing world, particularly in sub-Saharan Africa. The reasons behind this disorder are complex. For decades, efforts have focused on building training institutions. What is becoming increasingly clear, however, is that issues of supply, demand, and mobility (transnational, regional, and local) are central to the human-resource problem. Without substantial improvements in workforces, newly mobilised funds and commodities will not deliver on their promise. The global community needs to engage in four core strategies: raise the profile of the issue of human resources; improve the conceptual base and statistical evidence available to decision makers; collect, share, and learn from country experiences; and begin to formulate and enact policies at the country level that affect all aspects of the crisis.

Africa South of the Sahara↗

PubMed2006

Mobilising financial resources for maternal health.

Coverage of cost-effective maternal health services remains poor due to insufficient supply and inadequate demand for these services among the poorest groups. Households pay too great a share of the costs of maternal health services, or do not seek care because they cannot afford the costs. Available evidence creates a strong case for removal of user fees and provision of universal coverage for pregnant women, particularly for delivery care. To be successful, governments must also replenish the income lost through the abolition of user fees. Where insurance schemes exist, maternal health care needs to be included in the benefits package, and careful design is needed to ensure uptake by the poorest people. Voucher schemes should be tested in low-income settings, and their costs and relative cost-effectiveness assessed. Further research is needed on methods to target financial assistance for transport and time costs. Current investment in maternal health is insufficient to meet the fifth Millennium Development Goal (MDG), and much greater resources are needed to scale up coverage of maternal health services and create demand. Existing global estimates are too crude to be of use for domestic planning, since resource requirements will vary; budgets need first to be developed at country-level. Donors need to increase financial contributions for maternal health in low-income countries to help fill the resource gap. Resource tracking at country and donor levels will help hold countries and donors to account for their commitments to achieving the maternal health MDG.

Cesarean Section↗

PubMed2002

Bioinformatics and high throughput approach to create genomic resources for the study of bovine immunobiology.

The advent of technologies such as real-time reverse transcriptase polymerase chain reaction (RT-PCR) and cDNA microarrays herald a new era in the study of biological systems. In immunobiology, these advances have begun to impact studies of infectious diseases, inflammatory processes, and immune cell function. However, a lack of genetic reagents for domestic and companion animals has precluded widespread application of new technologies to studies in these systems. We have recently described development of cDNA microarrays for studying bovine immunobiology. Although powerful in revealing genes involved in immunological phenomena in cattle, these resources were limited by a lack of genes known to function in immune responses from other species, such as mouse and human. To address this shortcoming, we used a combination of bioinformatics and high throughput RT-PCR to create amplicons representing over 270 bovine genes whose orthologs in other species were known to function in immune responses. Amplified gene segments were prepared from cDNA representing RNA isolated from either unstimulated or concanavalin A (ConA) stimulated peripheral blood mononuclear cells (PBMCs). In total, 276 genes were amplified from cDNA representing unstimulated bovine PBMC RNA or from cDNA representing ConA stimulated bovine PBMC RNA. A web-accessible resource (http://gowhite.ans.msu.edu/public_php/gd-bovine-immunology.php) has been created to assist in dissemination of this novel resource. The web-accessible resource contains information on gene name, the forward and reverse primers used to amplify each segment, expected product size, and if the gene was found in unstimulated PBMCs or only in ConA stimulated PBMCs. Gene names appear as hyperlinks to the Genbank pages representing the bovine gene or expressed sequence tag (EST) used to generate each primer pair.

Animals↗

PubMed1997

Outcomes-based resource allocation for indigenous health services: a model for northern Australia?

Wide differentials continue to exist in mortality rates and other health outcomes between Aboriginal and non-Aboriginal Australians. In the Northern Territory (NT), where Aborigines make up 24% of the population, the all-causes age-adjusted Standardised Mortality Ratio for Aborigines compared to non-Aborigines has remained above 3 since the late 1970s, with significant regional variations. During 1995 an expenditure analysis was undertaken for primary health care (PHC) services in different regions of the NT and compared to mortality ratios. At the same time a method for needs-based funding was being developed which could replace the existing historical funding arrangements. In the first instance, the application of a simplified version of this Resource Allocation Formula (RAF) resulted in a significant shift of resources for new prevention program funding to regions of relatively high mortality and low per capita PHC expenditure. However, developing RAFs to redistribute at the margin within the NT is likely to generate further inequities between losing NT programs and counterparts in other states. If outcomes-based resource allocation is to be meaningful nationally, the reference point for the RAF should be national average PHC expenditure rather than existing state averages. There is a need for a combined approach to outcomes-based planning which takes into account both the equity arguments of resource allocation models and efficacy arguments to maximise health gains. Some of these arguments are explored in this paper.

Australia↗

PubMed2003

A meta-data-based learning resource server for medicine.

The World Wide Web (WWW) promises many advantages in the distribution and presentation of electronic learning modules for medical education. However, there is a well-known obstacle: finding the right offers on demand. We developed a solution based on international standards called Learning Resource Server Medicine (LRSMed), which provides a meta-data collection of electronic learning modules. Based on the meta-data, LRSMed offers a service for the learners to retrieve WWW resources at the time of learning. We used the IMS Learning Resource Meta-data Information Model as suitable meta-data specification, the eXtensible Markup Language (XML) as syntax for interfaces and the Oracle suite for implementation. LRSMed is available at http://mmedia.medizin.uni-essen.de/portal/. More than 260 learning resources are currently registered and described. So far a user-interface has been implemented which allows searching, commenting and editing. In the next future we will add an application programming interface (API) for the integration of LRSMed in portals, learning platforms and information systems of hospitals, medical practices or healthcare networks.

Internet↗

PubMed1997

The impact of anomia as a factor in a demand resource model of health.

The particular aim of the present study was to explore the interrelations between the construct of anomia, conceptualized as internal health demand or resource, and self-reported ill-health in the framework of a demand resource model. The four main constructs of this model were considered as recursive causal levels: (1) socio-economic data, (2) external resources/demands, (3) internal resources/ demands, and (4) ill-health. Study statistics comprised graphical models to reveal the relations between variables using the statistical program DIGRAM designed for discrete graphical models. This method of data analysis permits a focus on the link between anomia and the other three levels. The function of anomia as an intermediate data level which might prove to be an intervening variable can be evaluated. A total of 440 subjects of a random community sample were included in the final analysis. In the framework of a demand resource model, it was possible to confirm that the construct of anomia plays a key role in health outcome. Graphical models showed that a low degree of anomia is related to high psychological quality of life and few psychosomatic symptoms on the one hand, and to good social integration and emotional support, a low amount of daily hassles and high educational level on the other hand. As an overall conclusion, it can be stated that the evaluation by the graphical modeling procedure permits a good fit of theory with methods.

Adaptation, Psychological↗

PubMed2002

Developmental toxicity: web resources for evaluating risk in humans.

This review presents a brief overview of Internet resources that provides information on developmental toxicity. The advantages and limitations of these resources for evaluating human risk and where each one is useful for informing various stages of the risk assessment process (i.e. hazard characterization, dose-response assessment, exposure assessment and risk characterization) are reviewed. How these Internet resources can be utilized to obtain information on and evaluate the developmental risk associated with exposures during pregnancy will be illustrated using toluene. Translating information derived from laboratory and human population studies into clinical management prescriptions for individual patients is difficult. With the increasing availability of Internet resources that provide information relevant for developmental risk assessments, health care professionals will be better equipped to make more accurate estimations of potential risk for their patients.

Abnormalities, Drug-Induced↗

PubMed1997

Slow negative brain potentials as reflections of specific modular resources of cognition.

The paper summarizes a series of experiments in which the topography and the amplitude of slow event-related brain potentials (slow ERPs) was studied in cognitive tasks which imposed different amounts of load on functionally distinct processing modules. The results suggest that the topography of slow ERPs reflects the relative activation/inactivation of distinct cortical cell assemblies while the absolute amplitude of the negative maximum seems to reflect how much a particular cell assembly is activated at a particular time. Translated into the terminology of cognitive resource theories one could say that tasks which evoke distinct slow wave patterns draw on independent resources. Likewise, the amplitude of a slow wave pattern could be related to the construct of resource allocation, i.e. the larger the amplitude of a slow wave pattern the more resources of a particular type are allocated to a task. These findings are discussed with respect to possible generator mechanism of slow waves and in relation to possible causes of capacity limitations of the human information processing system.

Brain↗

PubMed2000

Effect of environmental enrichment upon resource holding power in fish in prior residence situations.

Resource holding power (RHP), as expressed by gaining dominance, can be affected by extrinsic and intrinsic factors. Extrinsic factors that increase the RHP include e.g. prior exposure to the contest area. The pay-off asymmetry hypothesis was tested according to which there is an asymmetry in the value the resident's territory has for the resident and intruders, i.e. the resident loses more than intruder opponents when losing the contest over a territory in which it has invested much energy during the exploration of food and shelter resources, during the settlement of conflicts with territorial neighbours, etc. This asymmetry will increase the resident's chance to win the fight over intruders. If the resident-intruder asymmetry is enhanced by presenting resource-rich territories to e.g. fish (structurally diverse or 'rich' aquariums), the hypothesis predicts that the resident's dominance chance (probability to win the fight) will be higher than in structurally 'poor' aquariums. It was found that residents were proportionately more often dominant (fight winners) than intruders in the rich compared to the poor aquariums in all seven tested fish species. This demonstrates that a high territory resource value (aquarium enrichment) significantly facilitates the expression of the resident's dominance advantage (prior residence effect). In contrast to dominance, aggressive behaviour before the dominance settlement did not generally differ between residents and intruders when compared in rich and poor aquariums. This suggests that dominance in itself and aggression prior to dominance settlement are at least partially guided by different motivational systems.

Journal Article↗

PubMed2004

Human resources: a common-sense discipline.

Being able to hire the right team members, keeping them engaged ina professional and productive environment, and avoiding litigation help keep the team functioning and meeting the everyday goals of providing quality patient care. Although these topics may seem complex, medical providers and professionals have resources available to them, such as the Human Resources department, the Medical Director, senior management,and legal counsel. Hiring the right people, creating a positive work environment, and avoiding litigation are all common sense principals that are relevant regardless of profession, industry, or company. Understanding how to apply the principles and concepts of Human Resources and personnel management can seem overwhelming: however, asking for help from the resources mentioned previously and applying the common sense information found in this article will help one to be a successful leader and practitioner.

Attitude of Health Personnel↗

PubMed1998

The influence of body mass index and learned resourcefulness skills on body image and lifestyle practises.

We examined the importance of body mass index (BMI-light, medium, heavy) and learned resourcefulness skills (low, medium, high) on body image perceptions and lifestyle practises in 184 undergraduate women who were of relatively normal weight. Significant main effects were observed for the BMI and the learned resourcefulness variables. Supporting previous literature, the heavier and medium weight groups of women were more dissatisfied with their weight and appearance in comparison to the lighter weight group, but all groups shared similar eating attitudes and lifestyle practises. Also as predicted, women with low resourcefulness skills had more eating disturbances, perceived less control over their lifestyle, were more preoccupied with their weight in comparison to the high and, to a lesser extent, the medium groups. Contrary to prediction, heavier weight women with low resourcefulness skills were neither the most dissatisfied with their body shape nor the most susceptible to acquiring unhealthy lifestyle practises and disturbed eating attitudes. Implications for lifestyle counselors are discussed.

Adult↗

PubMed2002

Community resources to promote successful aging.

Community resources are necessary for the health and well-being of older people. They can be organized with respect to the primary characteristic of successful aging they promote. Resources for avoiding disease and related disability include wellness programs, home health care, and mental health services. Resources that help older people sustain high functioning include senior centers, adult day care, and senior housing. Finally, active engagement with life is facilitated through employment services, learning experiences, and volunteer programs. Community resources for baby boomers in late life may differ from those available for today's elders. They will be no less important for successful aging, however.

Aged↗

PubMed1991

Nursing research instruments: pathway to resources.

Measurement of nursing phenomena involves locating and obtaining instruments that are reliable, valid, and feasible for use with an intended sample. Beginning with a clear conceptualization of the problem and delineation of the measurement framework, the process of finding and legally obtaining and using appropriate instruments can proceed. Resources for instruments are so numerous today that it is especially important to insure that valuable resources are not overlooked. Computerized resources offer comprehensive and efficient searches at low cost. The persistent nurse researcher who is aware of how to find and use the many resources available can select from among the numerous alternatives to measure nursing phenomena. The U.S. Copyright Act of 1976 has been shaped over the years by court cases and committee work to protect original work, including nursing research instruments. Knowledge of the provisions of copyright law may minimize the danger of unintentional violation while obtaining research instruments.

PubMedDate not supplied

Assessing life stressors and social resources: applications to alcoholic patients.

A growing body of evidence points to the importance of life stressors and social resources in the development and course of alcoholism and other substance abuse disorders. This article describes the Life Stressors and Social Resources Inventory (LISRES), which provides an integrated assessment of life stressors and social resources in eight domains: physical health, home/neighborhood, financial, work, spouse/partner, children, extended family, and friends. The indices were developed on data obtained at two points in time 18 months apart from four demographically comparable groups: alcoholic patients, depressed patients, arthritic patients, and non-problem-drinking adults. As expected, alcoholic patients reported more acute and chronic stressors and fewer social resources than did non-problem-drinking adults. More important, the indices were predictively related to changes in alcohol consumption, drinking problems, depression, and self-confidence. Procedures such as the LISRES have some potential clinical and research applications and may be helpful in examining the process of recovery and relapse in substance abuse disorders.

Adult↗

PubMed2000

Internet resources and web pages for pediatric surgeons.

The Internet, the largest network of connected computers, provides immediate, dynamic, and downloadable information. By re-architecturing the work place and becoming familiar with Internet resources, pediatric surgeons have anticipated the informatics capabilities of this computer-based technology creating a new vision of work and organization in such areas as patient care, teaching, and research. This review aims to highlight how Internet navigational technology can be a useful educational resource in pediatric surgery, examines web pages of interest, and defines ideas of network communication. Basic Internet resources are electronic mail, discussion groups, file transfer, and the Worldwide Web (WWW). Electronic mailing is the most useful resource extending the avenue of learning to an international audience through news or list-servers groups. Pediatric Surgery List Server, the most popular discussion group, is a constant forum for exchange of ideas, difficult cases, consensus on management, and development of our specialty. The WWW provides an all-in-one medium of text, image, sound, and video. Associations, departments, educational sites, organizations, peer-reviewed scientific journals and Medline database web pages of prime interest to pediatric surgeons have been developing at an amazing pace. Future developments of technological advance nurturing our specialty will consist of online journals, telemedicine, international chatting, computer-based training for surgical education, and centralization of cyberspace information into database search sites.

Child↗

PubMed2003

Men's experiences and their resources from cancer diagnosis to recovery.

This study describes the experiences and resources of male cancer patients in Finland during the trajectory of their illness. A semi-structured interview schedule was used to collect data on falling ill with cancer, on periods of treatment (surgery, chemotherapy, radiation therapy), and on convalescence. The participants (n=8), aged 42-64 (mean=53) were interviewed in a clinic setting in connection with a check-up visit. The interviews were tape-recorded and transcribed for qualitative content analysis. The male cancer patients described their experiences through the illness trajectory in terms of suspicions, their encounter with cancer, and the cancer becoming a reality. During treatment, men described their experiences in terms of changes in body image, individual illness experiences, and new social roles. Men's experiences during the convalescence period included physical restoration, anxiety following treatment regimes, reflection, and social roles at transition. The results also indicated that men did not consider their status as a chronic one, but rather as a passing and relatively short stage in their life. Both intra- and extrapersonal resources were described: the former included body image and capacity, self-understanding, social situation, and psychological resources; and the latter wives, children, colleagues, health-care personnel, fellow patients, health-care interventions and society. Extrapersonal resources included informational, emotional, and evaluative support, as well as concrete help.

Adult↗