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At least 955 records · Page 53Linked to original sources
PubMed1995

Audit of 114 non-neoplastic vulvar biopsies.

OBJECTIVE: The purpose of this study was to show the benefits and limitations of vulvar biopsy in the setting of a multidisciplinary clinic specialising in non-neoplastic diseases of the vagina and vulva. DESIGN: One hundred and fourteen vulvar biopsies were reviewed and classified according to the classification of the International Society for the Study of Vulvar Diseases. RESULTS: The histological diagnoses were lichen sclerosus 25%, lichen simplex chronicus 35%, non-erosive inflammatory dermatoses comprising psoriasis, spongiotic dermatitis, dermatophytosis and psoriasiform dermatitis 13%, erosive vulvitis and lichen planus 9%, nonspecific inflammation 6%, miscellaneous 9% and normal 4%. CONCLUSIONS: Biopsies in cases of lichen sclerosus were useful for confirmation of clinical diagnosis and to exclude early invasive malignancy. In lichen simplex chronicus, biopsies helped exclude an underlying dermatosis requiring specific treatment. Psoriasis, spongiotic dermatitis, dermatophytosis and excoriated lichen simplex chronicus posed a common clinical differential diagnosis of the reddened vulva. The eroded vulva often proved a diagnostic problem clinically and histologically. The clinical syndrome of vestibulitis did not have a specific histological picture, and biopsies showed nonspecific inflammation, mild hyperplasia or were normal. No case of squamous cell hyperplasia was diagnosed and the place of this diagnosis in the ISSVD classification needs review.

Adolescent↗
PubMed1978

Grenz rays: adequate or antiquated?

Selected benign dermatoses, recalcitrant to most other forms of therapy, respond to grenz-ray therapy. When appropriately administered, this is a safe treatment for such conditions. This paper delineates the practical application of grenz-ray therapy at the present time.

Dermatitis, Seborrheic↗
PubMed2004

The simplex (differentiated) variant of vulvar intraepithelial neoplasia.

BACKGROUND: The simplex (differentiated) variant of vulvar intraepithelial neoplasia is rarely reported. It is regarded as more likely than "classic" carcinoma in situ to be associated with invasion and can be easily mistaken for benign lesions. OBJECTIVE: The objective was to present a case of simplex variant of vulvar intraepithelial neoplasia in a 67-year-old woman that was initially misdiagnosed as lichen simplex chronicus. METHODS: A case report is reported and the literature is reviewed. RESULTS: Surgical excision with a free margin of 5 mm was performed and no evidence of recurrence was noted during the follow-up period of 6 months. CONCLUSION: The simplex vulvar intraepithelial neoplasia is an easily overlooked premalignant disease, and it can be cured with surgical treatment if diagnosed correctly and early.

Aged↗
PubMed1973

The aging skin.

Explore the source record for details and available documents.

Age Factors↗
PubMed1997

The cutaneous-vulvar clinic revisited: a 5-year experience of the Columbia Presbyterian Medical Center Cutaneous-Vulvar Service.

OBJECTIVE: To review the recent experience of a busy referral cutaneous-vulvar service. STUDY DESIGN: 500 randomly chosen charts from the last 5 years of patients seen at the Columbia Presbyterian Medical Center Cutaneous-Vulvar Service were reviewed. Information was entered into a computer data base and analyzed. RESULTS: The most common presenting condition was vulvar vestibulitis (36.2%), followed by lichen sclerosus (19.2%) and vaginitis/vaginosis (14.8%). Most patients had undergone a variety of therapies prior to referral. Many were treated for moniliasis in the absence of clinical evidence prior to our evaluation. Most patients responded well to appropriate therapy. CONCLUSIONS: A variety of primary care providers see women with cutaneous-vulvar symptomatology. Awareness of prevalent conditions will lead to correct diagnosis and treatment. We emphasize the importance of interdisciplinary consultation in difficult cases.

Adult↗
PubMed1983

Pityriasis amiantacea and psoriasis. A follow-up study.

59 patients with pityriasis amiantacea (PA) were followed up after 8 years on average. 15% had suffered from psoriasis and 19% were aware of psoriasis in their relatives. The incidence of psoriasis was significantly higher (p less than 0.01) than in the Scandinavian population, and the predisposition to psoriasis was significantly higher than in the population (p less than 0.001), but significantly lower (p less than 0.01) than in psoriatic patients. PA seems to be a manifestation of psoriasis in many cases.

Adolescent↗
PubMed1982

How are women sicker than men? An overview of psychosomatic problems in women.

An overview is presented of psychosomatic problems in women - the epidemiology, physiology and psychology. Surveys of sickness rates in women and psychological studies are used as a basis of speculation about higher female morbidity rates. Theories of psychosomatic illness, the somatic concomitants of hysteria and alexithymia are reviewed as they pertain to observations of gender differences in disease phenomena. A clinical case is presented of thyrotoxicosis, one of the illnesses predominantly found in women.

Arthritis, Rheumatoid↗