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Results for “INTESTINAL ATRESIA”

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PubMed1998

Maternal serum alpha-fetoprotein in fetal anal atresia and other gastro-intestinal obstructions.

The fetal gastro-intestinal (GI) tract contributes to alpha-fetoprotein (AFP) levels in amniotic fluid and hence to those in maternal serum (MS). This study retrospectively analysed results of second trimester MSAFP screening in cases of fetal GI tract obstruction. 18 cases of fetal GI obstruction were diagnosed amongst 17,036 women who underwent MSAFP screening between 1979 and 1997: seven had oesophageal atresia, four had duodenal atresia, six had anal atresia, and one had both anal and oesophageal atresia. MSAFP in pregnancies of a fetus with anal atresia was significantly lower than the population median. MSAFP in cases of fetal oesophageal or duodenal atresia was low but these differences did not reach significance.

Anus, Imperforate↗
PubMed1972

Congenital stenosis and atresia of the jejunum and ileum.

The macroscopic and microscopic findings in 12 cases of stenosis and/or atresia of the jejunum and ileum are presented. There was considerable uniformity within the series with overlapping of cases of atresia, stenosis, and gut infarction. An analysis of associated lesions in cases coming to necropsy suggests that the infants were suffering from shock. In nine out of the 12 cases there was evidence of intrapartum asphyxia and in eight cases evidence of retardation of intrauterine growth. It is argued that, since many of the associated complications of pregnancy are known to be of importance in the aetiology of gut infarction in the neonatal period, they are likely to be of aetiological significance in the development of atresia and stenosis of the gut. A review of perinatal deaths shows that gut ischaemia of varying degrees of severity is a common finding at necropsy, being noted in 19 out of 56 cases studied. It is suggested that stenosis and atresia are sequelae of previous gut ischaemia.

Asphyxia↗