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Prospective study of intraocular pressure 2 1/2 years after intracapsular cataract extraction and implantation of a semiflexible anterior chamber lens.

Fifty-one patients available for a 2 1/2 year follow-up after intracapsular cataract extraction and implantation of the semiflexible McGhan/3M, style 70 anterior chamber lens were evaluated for intraocular pressure (IOP). No significant change in the IOP could be demonstrated despite progression of iris-like tissue adhesions between the iris and lens haptics at or close to the trabecular meshwork. Four eyes (7.8%) had IOPs greater than or equal to 22 mm Hg without medication, and four other eyes used timolol eyedrops with subsequent IOPs less than or equal to 18 mm Hg. Eight eyes (15.7%) demonstrated an IOP increase greater than or equal to 25% over baseline pressures.

Anterior Chamber↗

Results of trabeculectomy combined with phacoemulsification versus trabeculectomy combined with extracapsular cataract extraction in patients with advanced glaucoma.

We compared the results of trabeculectomy combined with phacoemulsification (n = 16) with those of trabeculectomy combined with extracapsular cataract extraction (n = 18). There was no significant difference between the two groups in terms of early or chronic postoperative intraocular pressure (IOP) control or in terms of the number of glaucoma medications prescribed postoperatively. However, by 12 weeks postoperatively, bleb height and extent were significantly greater in the phacoemulsification group. There was no significant difference between the groups in terms of postoperative spheroequivalent, astigmatism, or cylindrical axis. The mean final visual acuity, however, was less in the extracapsular group. We conclude that phacoemulsification combined with trabeculectomy offers a safe and effective technique to control postoperative IOP in patients with glaucoma.

Aged↗

Cataract extraction in uveitis: comparison of aphakia and posterior chamber lens implantation.

We reviewed the charts of 39 patients (45 eyes) with uveitis who underwent cataract extraction (intracapsular or extracapsular) with or without implantation of a posterior chamber intraocular lens (IOL) at the Royal Victoria Hospital, Montreal, between 1981 and 1990. The nine eyes with Fuchs' iridocyclitis in which an IOL was implanted had good visual results and few postoperative complications. The 18 eyes with uveitis other than Fuchs' iridocyclitis that received an IOL did not show a greater risk of postoperative complications than those left aphakic (n = 17), and the postoperative visual acuity was comparable to that of the aphakic eyes. Although the numbers are small, we conclude that the presence of uveitis does not automatically exclude posterior chamber pseudophakia.

Adult↗

Trabeculectomy with 5-fluorouracil subsequent to circular buckling operation and cataract extraction.

Six patients, each with one eye that had previously undergone circular buckling surgery for the repair of retinal detachment before or followed by cataract extraction with or without intraocular lens implantation, underwent trabeculectomy with 5-fluorouracil (5-FU) for intractable glaucoma. Surgery was done through scarred subconjunctival tissues that were excised partially. The total doses of 5-FU ranged from 65 to 100mg (mean +/- standard deviation, 84.2 +/- 13.2mg) Eight to 47 months later, intraocular pressures were 18mmHg in five eyes, two of which were not receiving hypotensive medications. In the sixth eye, the intraocular pressure was 26mmHg with maximum hypotensive treatment. Intraocular pressures in the six eyes were significantly lower postoperatively than preoperatively (P < .05). This preliminary study suggests that filtering surgery with 5-FU may be beneficial after intraocular operations even in eyes where it is done through postoperative scarred subconjunctival tissues.

Adult↗

Cystoid macular oedema after extracapsular cataract extraction and intraocular lens implantation in diabetic patients without retinopathy.

Postoperative onset or aggravation of cystoid macular oedema (CMO) in diabetic patients after extracapsular cataract extraction (ECCE) with intraocular lens (IOL) implantation is a frequent problem. At present little is known about the occurrence and prognosis of this complication in diabetics with no clinically detectable diabetic retinopathy (DR). Twenty five diabetic eyes (24 subjects) without DR and 45 normal eyes (44 subjects) were studied before surgery and 30, 90, 180, 360 days after ECCE and posterior chamber IOL implantation. Fluorescein angiography was performed at each examination. The frequency of angiographic CMO in the two groups was comparable 30 days after surgery but was significantly higher in diabetic eyes at 90, 180, and 360 days. This finding is probably related to an impairment of the blood-retinal barrier in diabetics. Final visual acuity, however, was similar in the two groups.

Aged↗

[Prevention of retinal detachment. I. Cryopexy before cataract extraction. Preliminary report].

The authors discuss the results of cryopexy applied prophylactically in 32 eyes. The freezing was executed at least 6 weeks before the cataract extraction in eyes endangered by retinal detachment. This were the high myopia eyes, so called fellow eyes and eyes in persons aged between 30 and 40 years. Retinal detachment did not occur in either of the observed eyes in the period of 1-5 years.

Adult↗

Iris angiography after cataract extraction and the effect of indomethacin eyedrops.

To test the efficacy of topical indomethacin eye drops in preventing cystoid macular edema (CME) postcataract extraction, iris fluorescein and fundus fluorescein angiography were performed in two series of eyes that underwent intracapsular cataract extraction; 25 control eyes and another 25 eyes receiving indomethacin eye drops. In the latter group, 1% indomethacin eye drops were given three times a day, from 1 day preoperatively to 4 weeks postoperatively. In these two groups, there was a statistically significant difference in the findings on iris fluorescein angiography in the early and late period. There appeared to be a correlation between the degree of dye leakage on iris fluorescein angiography and the occurrence of CME. Fundus examination showed 6-9 weeks postoperatively perifoveal vascular leakage in 28% of the control group and in 8% of the indomethacin group. The results show from this study support the theory that prostaglandin form an etiological factor of CME.

Aged↗

Argon laser photocoagulation of inner wound vascularization after cataract extraction.

A 64-year-old man had vascular ingrowth of a surgical wound resulting in recurrent hyphema and pupillary block glaucoma three years after cataract extraction. Argon laser photocoagulation of an abnormal vessel in the inner lip of the wound resulted in complete clearing of a chronic hyphema, with a four-month follow-up. We used 500-micron laser spots of 2,000 mW and 0.5 seconds' duration to closr the vessels. This approach is recommended for its relative safety and simplicity.

Argon↗

Causes of presenile cataracts extracted at the Halifax Infirmary Hospital, 1976-85.

To identify the main causes of presenile cataract formation, we reviewed the charts of 287 consecutive patients (341 eyes) aged 20 to 49 years who underwent cataract extraction at the Halifax Infirmary Hospital between 1976 and 1985. No cause for cataract formation could be determined in 34% of the patients. The leading identifiable causes were trauma (37% of cases), associated ocular disease (24%), associated systemic disease (14%) and use of medications (9%). There was no difference in sex or use of alcohol or tobacco between the patients with idiopathic cataracts and those in whom cataracts were associated with organic disease.

Adult↗

Extracapsular cataract extraction and posterior-lip sclerectomy with viscoelastic.

A review of 15 cases suggests that posterior-lip sclerectomy can be performed safely with extracapsular cataract extraction (ECCE) and posterior chamber lens implantation. The anterior chamber was filled with viscoelastic at the end of each procedure; no case required reoperation for shallow chamber or hypotony. The mean intraocular pressure after 1 year was 12.1 mm Hg. The astigmatism induced by the triple procedure did not differ significantly from that caused by ECCE alone during the initial 2 postoperative years. A new mathematical model that describes the change over time of postoperative astigmatism associated with these procedures is described.

Aged↗

Long-term effect of cataract extraction on the function of an established filtering bleb.

BACKGROUND AND OBJECTIVE: For patients with advanced glaucoma, care must be taken in the management of cataract to prevent loss of long-term intraocular pressure (IOP) control. The authors evaluated the effect of extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (PC IOL) implantation via the inferotemporal limbal approach on the function of an established glaucoma filtering bleb. PATIENTS AND METHODS: Twenty-three eyes of 21 patients with a minimum of 48 months of follow-up (range 48 to 97 months) were retrospectively evaluated. IOP, bleb status, visual field, and visual acuity were compared before and after operation. RESULTS: Average IOP increased from 8.7 mm Hg preoperatively to 12.2 mm Hg at last follow-up. Six blebs (26.1%) decreased in size, 11 (47.8%) did not change, 4 (17.4%) increased in size, and 2 (8.7%) were lost and required refiltration. At last follow-up, 23 eyes had an IOP of less than 20 mm Hg and did not show progression of glaucoma damage by optic disc or visual field evaluation. Six eyes required resumption of medical therapy and 2 eyes required refiltration for adequate control. CONCLUSION: ECCE with PC IOL implantation via the inferotemporal limbal approach in the presence of an established filtering bleb is effective in the long-term management of the glaucomatous eye with cataract.

Aged↗

Intraocular pressure following extracapsular cataract extraction and posterior chamber intraocular lens implantation.

Knowledge of the incidence of both short- and long-term elevation of intraocular pressure (IOP) after extracapsular cataract extraction (ECCE) and posterior chamber intraocular lens (PC-IOL) insertion is essential for the practicing ophthalmologist. We reviewed retrospectively the IOP data in 384 consecutive patients (506 eyes) that underwent the above procedure. A postoperative rise of 8 mm Hg above baseline or above 23 mm Hg was observed in 149 eyes (29%). Secondary glaucoma well controlled medically developed in 21 eyes (4%). Three eyes developed glaucoma after the first year postoperatively. Therefore, over the total follow-up period of 6 years, 24 eyes (4.7%) developed pseudophakic glaucoma. None, however, required laser or other surgical intervention. These results further support the prevailing view that ECCE with PC-IOL is the procedure of choice.

Adult↗

Changes of the corneal endothelium following intracapsular cataract extraction with implantation of semiflexible anterior chamber lenses. I. Results of the early post-operative period.

A consecutive group of 103 patients with senile cataract underwent intracapsular cataract extraction and implantation of a semiflexible anterior chamber lens. After 6 month of follow-up, there was an average decrease of 20% +/- 15% in central corneal endothelial cell density and an average vertical disparity of 32% +/- 20% between central and superior endothelial areas. The endothelial cell loss was not correlated with pre-operative cell density. There was a positive correlation between age and cell loss and between age and vertical disparity. Findings in eyes with cornea guttata did not differ significantly from those without guttata. Anterior vitrectomy did not increase endothelial cell loss significantly. Maintenance of a deep anterior chamber by pre-operative oculopression or by instillation of Na-hyaluranate had no significantly different effect on the corneal endothelial cell loss.

Adult↗

Effects of intracameral carbachol and acetylcholine on early postoperative intraocular pressure after cataract extraction.

We performed a randomized, prospective study to evaluate the effect of intraoperative, intracameral carbachol or acetylcholine on early postoperative intraocular pressure(IOP) after extracapsular cataract extraction(ECCE) and posterior chamber lens(PCL) implantation. Fifty-six eyes of 56 patients scheduled for routine ECCE and PCL implantation were randomly assigned into three groups: (1)carbachol infusion (19 eyes) (2) acetylcholine infusion (15 eyes) (3)balanced salt solution (BSS) infusion (control, 22 eyes). We compared the preoperative IOP, early postoperative IOP, postoperative 24 hours IOP and postoperative 1 week IOP. In the measurement of early postoperative IOP, IOP was measured at least twice at 3, 6 or 9 hours postoperatively. There was no significant difference in IOP between the three groups preoperatively, at postoperative 3 hours, and 1 week. At postoperative 6 hours, both the carbachol infusion group and acetylcholine infusion group were significantly different from the BSS infusion group. At postoperative 9 and 24 hours, only carbachol infusion group had a significant difference from BSS infusion group in suppression of postoperative IOP increase. Our results suggest that intraoperative, intracameral administration of carbachol or acetylcholine prevents early postoperative IOP increase, and that carbachol has a more lasting effect.

Acetylcholine↗