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Management of incomplete spontaneous abortion with suction curettage in the pediatric emergency department.

Pregnancy complications, including spontaneous abortion, are increasingly common reasons for teenage girls to seek medical care in pediatric emergency departments (EDs). A protocol was implemented in our department to identify patients with spontaneous abortion who would be candidates for outpatient management. We describe three cases of spontaneous abortion managed with suction curettage in our pediatric ED in collaboration with our obstetric/gynecologic colleagues. There are no reports in the pediatric literature regarding the role of suction curettage in the pediatric ED.

Abortion, Incomplete↗

Suction lipectomy during flap reconstruction provides immediate and safe debulking of the skin island.

Immediate suction lipectomy combined with flap reconstruction has not been reported to date. Concern of skin island compromise has swayed clinicians from attempting synchronous debulking of generous skin island tissue during primary flap reconstruction. To date, several reports have documented the safe use of liposuction during mobilization of skin flaps as a minimally invasive, undermining tool in the cervical neck area. Additionally, liposuction has been used safely as an adjunct to rhytidectomy procedures over areas containing vital structures. The authors report 2 patients in whom generous skin island tissue prevented primary closure after transposition of the flap into its recipient site. Aspiration of subcutaneous tissue in a transverse rectus abdominis musculocutaneous flap and gluteus musculocutaneous rotational flap for breast and sacral ulcer reconstructions respectively resulted in appropriate debulking of the skin island without any flap skin compromise. The findings of this report may provide impetus for further clinical investigations establishing the utility of combined suction lipectomy and flap reconstruction.

Adult↗

Suction feeding in orchid bees (Apidae: Euglossini).

Energy flux during nectar feeding is maximized at an intermediate sugar concentration, the value of which depends on the morphology of the feeding apparatus and the modality of fluid feeding. Biomechanical models predict that a shift from capillary-based lapping to suction feeding will lead to a decrease in this optimal sugar concentration. Here, I demonstrate that the four major genera of orchid bees (Apidae: Euglossini) are suction feeders and provide experimental evidence that the feeding optimum for one species, Euglossa imperialis, falls below the optimum for bee taxa that lap.

Analysis of Variance↗

Vortices and flow reversal due to suction slots.

Suction into small two- or three-dimensional surface slots inside an otherwise planar boundary-layer is examined theoretically through a combined analytical and computational approach. Increasing suction strength leads to enhanced nonlinear structures with flow reversals or trailing vortices.

Journal Article↗

Evaluation of cellular injury in skin utilizing enzyme activities in suction blister fluid.

Suction blisters were produced on the skin of anesthetised rats and marker enzyme activities measured in the blister fluid from normal and chemically damaged skin. Cutaneous application of tributyltin, in doses known to produce morphological damage, increased the activity of a number of enzymes in the blister fluid within 2.5 hr. The increases were dose-related and resulted from cutaneous damage as they were detected at times and doses when there were no comparable changes in plasma enzyme activities. Increased enzyme levels in suction blister fluid from chemically damaged skin appear to reflect the degree of skin injury and may offer a direct and quantitative assessment of this injury.

Acetylglucosaminidase↗

Acroangiodermatitis (pseudo-Kaposi sarcoma) associated with verrucous hyperplasia induced by suction-socket lower limb prosthesis.

Increasing use of suction-socket lower limb prostheses has been associated with an increased frequency of dermatological manifestations, linked to the fact that the skin of the amputation stump must adapt to an entirely new environment. In particular, verrucous hyperplasia and rare cases of acroangiodermatitis (pseudo-Kaposi sarcoma) have been described. We report a case of amputation stump dermatitis, clinically resembling verrucous hyperplasia, but with predominant histological aspects of acroangiodermatitis in a patient with a suction-socket lower limb prosthesis.

Acrodermatitis↗

Bathtub suction-induced purpura.

We report two cases of bathtub suction-induced purpura. Two girls, ages 9 and 14 years, developed recurring purpura "spontaneously" in the same lower back location and in the same U-shaped distribution. The patients had similar histopathologic findings, with extravasated erythrocytes and a sparse superficial inflammatory infiltrate. After extensive evaluation, one patient eventually admitted to self-inducing her lesions by creating suction against a bathtub. The second patient denied self-inflicting her lesions; however, her purpura improved when she stopped taking baths.

Adolescent↗

Measurement of skin elastic properties with a new suction device (II): systemic sclerosis.

We previously reported the skin elastic properties of normal subjects as measured by a newly developed suction device (6). In the present report, we examined the skin elastic properties of 62 patients with systemic sclerosis (SSc), clinically diagnosed as limited or diffuse type. We measured the skin elastic properties on the forearm and chest and investigated correlations with disease type and clinical skin score. Patients with the diffuse type SSc showed significantly lower values than those with the limited type SSc or normal subjects in distention and retraction ability at the chest and forearm. This suction device is clinically useful for the objective evaluation of skin elastic properties in diffuse systemic sclerosis.

Adult↗

Basement membrane components and galactosylhydroxylysyl glucosyltransferase in suction blisters of human skin.

Basement membrane components and collagen biosynthesis were studied in suction blisters in human skin. The basement membrane components were characterized by immunofluorescence using specific antibodies to type IV collagen, laminin and fibronectin, and collagen biosynthesis was studied by assaying galactosylhydroxylysyl glucosylatransferase. In suction blisters, the separation of epidermis and dermis occurred above the lamina lucida, indicating that the basement membrane, composed of lamina lucida and lamina densa, forms a mechanically strong entity. During the regeneration phase of blisters, type Iv collagen and laminin were not observed in the old epidermal blister roof. This indicates that keratinocytes when separated from the underlying basement membrane or connective tissue do not synthesize laminin or type IV collagen. Galactosylhydroxylysyl glucosyltransferase activity could be demonstrated in blister fluid and was about the same as in serum when expressed on the basis of protein in fresh blisters. It increased by 2-3 fold during the repair of blisters, indicating that there was local production of this enzyme. Further studies revealed that pure epidermis contained galactosylyhdroxylysyl glucosyltransferase and hydroxyprolineand this suggests that epidermis may synthesize some collagen type which, according to these studies, is not type IV (basement memebrane) collagen.

Adult↗

The effect of Goeckerman therapy on interferon in serum and suction blister fluid from patients with psoriasis.

An infectivity inhibition micromethod was used to detect interferon (IFN) in sera and suction blister fluids from 35 patients with untreated psoriasis vulgaris. IFN (greater than or equal to 16 units/ml) was detected in 56% of the sera (median 25 units/ml), in 77% of the suction blister fluids from lesional skin (median 35 units/ml) and 33% of the blister fluids from unaffected skin (median 10 units/ml). IFN levels were significantly higher in blister fluids from lesional skin than from unaffected skin (P less than 0.05) indicating local IFN production. Results of characterization experiments indicated the presence of both acid stable and acid labile IFN-alpha as well as IFN-gamma in sera and blister fluids. After Goeckerman therapy, IFN was detected in 91% of the sera (median 89 units/ml), in 90% of the blister fluids from lesional skin (median 50.5 units/ml) and in 72% of the blister fluids from unaffected skin (median 26.5 units/ml). The IFN levels in sera were significantly higher than in blister fluids from both lesional skin (P = 0.05), and unaffected skin (P = 0.001). Furthermore, after Goeckerman therapy the IFN levels in blister fluids from unaffected skin and in sera were significantly higher than those in untreated patients (P = 0.01 and P = 0.0001) respectively. The results indicate that UVB radiation induces systemic IFN production.

Adolescent↗

Determination of released CD4 and CD8 antigens in the suction-blister fluid and horny-tissue extract in patients with psoriasis.

The amounts of soluble CD4 and CD8 antigens were measured in suction-blister fluid and extracts of horny tissue in patients with psoriasis. The levels of soluble CD4 and CD8 in the suction-blister fluid of lesional skin in psoriasis was significantly higher than from normal skin and the uninvolved skin in psoriasis. Levels of soluble CD4 and CD8 in the extracts of horny tissue in psoriasis were significantly higher than those from non-psoriatic skin.

Adolescent↗

The use of bacteriophage as tracers of aerosols liberated by sludge suction appliances.

Three bacteriophage tracers were added to 600-1 containers of water and simulated latrine sludge to provide high titres of tracer in aqueous and semi-aqueous media. After a period of mixing and stabilization, media were removed from the containers with suction hoses coupled to the vacuum pump of one of two sludge suction tankers. Exhaust air from the appliances was sampled by cyclone sampler and assayed for the presence of tracer organisms carried over during the emptying process. In the experiments the appliances were operated at different vacuum pump speeds, drawing both aqueous and semi-aqueous (simulated sludge) media. Air around one tanker was also sampled during the emptying, under pressure, of the vacuum vessel. The degree of aerosolization and expulsion of tracer bacteriophage by the vacuum appliances was consistently low, regardless of medium and pump air flow. In contrast, the proportion of tracer retained within the appliances was very high, exceeding the proportion expelled by a minimum of 8 log10 orders of magnitude and a maximum of greater than 11 log10 orders. The highest total of tracer bacteriophage was recovered during the pressure emptying of the vacuum vessel of one tanker. The results may be used for assessing and comparing potential public health hazards associated with the handling of wastewater sludge by vacuum appliances.

Aerosols↗

A randomised comparison of oral and vaginal misoprostol for cervical priming before suction termination of pregnancy.

OBJECTIVE: To assess the effectiveness and acceptability of oral misoprostol, self-administered 12 h before surgery, as a cervical priming agent prior to day case suction termination of pregnancy. DESIGN: Randomised trial comparing oral misoprostol with the local standard regimen of vaginal misoprostol. SUBJECTS: Sixty consecutive women scheduled for day case suction termination in one gynaecology unit. INTERVENTIONS: Cervical priming with misoprostol 400 mg orally, 12 h prior to surgery or 800 mg vaginally, two to four hours prior to surgery. MAIN OUTCOME MEASURES: Basal cervical dilatation, cumulative force required to dilate the cervix to 9 mm, operative blood loss and side effects (nausea, vomiting, diarrhoea, abdominal pain and vaginal bleeding). RESULTS: There were no significant differences between the oral and vaginal treatment groups in relation to basal dilatation, cumulative force to achieve 9 mm dilatation or gastrointestinal side effects. However, those in the oral group experienced more severe pain and heavier pre-operative bleeding. Two patients in the oral group experienced incomplete abortion at home after taking misoprostol and a further patient required early admission because of heavy bleeding. CONCLUSIONS: Because of the unpredictability of action of oral misoprostol, with incomplete abortion or heavy bleeding occurring prior to admission in three patients, we cannot recommend the dosage schedule evaluated here for routine clinical use.

Abortifacient Agents, Nonsteroidal↗

Meconium aspiration--role of obstetric factors and suction.

Meconium aspiration occurred in 66 of 120 infants with meconium-stained liquor admitted to a Neonatal Unit. Four of the 66 infants died, whilst 17 other required ventilatory support. Meconium aspiration syndrome, especially when severe, was more likely if the mother was a smoker, hypertensive, anaemic, Maori or the pregnancy was greater than 42 weeks' gestation. Meconium aspiration was also associated with thick meconium, prolonged labour, late fetal heart decelerations and inadequate suctioning of the airway at birth. Although meconium-stained liquor is a common occurrence in labour, a bad neonatal outcome will only be obviated by vigilant intrapartum care and active suctioning of the infant's airway at birth. Once aspiration has occurred, intensive treatment is often required and sometimes fails.

Ethnicity↗

Bilateral recording of human intraocular pressure with an improved applanating suction cup tonograph.

An improved applanating suction cup for continuous recording of human intraocular pressure is described. The new cup adheres better, is easier to calibrate, and is simpler to handle, mainly due to a different curvature of the applanating surface. The interspace between the applanating and the applanated surface, in which the pressure is measured, is continuously flushed with saline from a flow system (Intraflo) connected to the dome of the pressure transducer. The suction that attaches the cup to the cornea is - as in the previous model - provided by a saline filled tube hanging from the cup. In 51 human cadaver eyes the calibration for static pressures and pressures oscillating up to 124 cycles per min was: intraocular pressure = 0.9 X cup pressure -3 (mmHg), r = 0.995. The cup reduced ocular rigidity by 5% only and increased the intraocular pressure transiently by 4 mmHg when applied. Simultaneous bilateral recordings were obtained in 400 normo- or hypertensive eyes from 206 subjects. The cup was atraumatic, and the method can be strongly recommended when accurate, bilateral pressure recordings are desired for periods up to one h in supine subjects. At intraocular pressures above 35 mmHg, the tonograph may underestimate the pressure under certain, unfavourable conditions.

Tonometry, Ocular↗

Acute IOP elevation with scleral suction: effects on retrobulbar haemodynamics.

AIMS/BACKGROUND: Mechanical and vascular factors may both contribute to glaucoma. This study investigated the relation of mechanical to vascular factors by examining how acute IOP elevation altered flow velocities in the central retinal and ophthalmic arteries. METHODS: IOP was elevated from a baseline near 14 to approximately 45 mm Hg using suction ophthalmodynamometry. During recovery from scleral suction, IOP fell to near 8 mm Hg. At each IOP, peak systolic and end diastolic velocities (PSV and EDV) were measured in the central retinal and ophthalmic arteries using colour Doppler imaging (Siemens Quantum 2000). Eleven healthy people served as subjects. RESULTS: Acute elevation in IOP had no effect upon PSV, EDV, or the derived resistance index in the ophthalmic artery: flow velocities in this vessel were identical at IOP of 8 mm Hg or 45 mm Hg. In contrast, in the central retinal artery, PSV and EDV fell, and the resistance index rose, in steady progression as IOP was acutely elevated (each p < 0.01). At IOP of 45 mm Hg, EDV was virtually absent and the resistance index was very nearly 1.0. CONCLUSION: Ophthalmic arterial haemodynamics are unrelated to acute fluctuations of the IOP over a wide range, suggesting that ocular hypertension itself cannot induce vascular dysfunction in this artery. In contrast, flow velocities in the central retinal artery were highly IOP dependent, implying that haemodynamic and mechanical factors are closely linked in this vascular bed.

Acute Disease↗

A paediatric tube and capsule for suction biopsy of the small intestinal mucosa designed for direct nasogastric intubation.

The use of a modified paediatric tube and capsule for suction biopsy of the mucosa of the small intestine is discussed. The tube is small in diameter and can be introduced through the nose without local trauma and with minimal discomfort. The intubation technique was followed in 72 instances to obtain suction biopsies from the proximal mucosa of the small intestine in protein-calorie malnourished children, and the results obtained with this instrument are also presented.

Biopsy↗

Determination of protoporphyrin in plasma and suction-blister fluid from light-irradiated and non-irradiated skin in protoporphyria patients.

At various times of the year the protoporphyrin level in the plasma of 11 patients with erythropoietic protoporphyria was determined. In the winter as well as in the summer, when the patients received carotenoids, an area on one forearm of 10 patients was irradiated with artificial (xenon arc) light, after which suction blisters were made on both forearms. Protoporphyrin levels were determined in the plasma and in the blister fluid from both areas. Suction-blister fluid was considered representative of the interstitial fluid in the dermis. In the winter the protoporphyrin levels of the blister fluid from the irradiated area were significantly higher than in the fluid from the non-irradiated area. In the summer this difference was not significant. The possible implications of these findings are discussed.

Blister↗