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At least 937 records · Page 52Linked to original sources
PubMed1983

[Effect of the R plasmids of Salmonella typhimurium strains of various origins on salmonella virulence].

Antibiotic-multiresistant S. typhimurium strains, phagovars 20 and 25, of different origin (isolated in hospital infections transferred through everyday contacts and by alimentary route, as well as from samples taken from open water basins and sewage) have been found to carry both transmissible and nontransmissible R plasmids. The frequency of the transfer of R plasmids to Escherichia coli K-12 C 600 rif varies within 0.6 X 10(-5) and 0.7 X 10(-3) per donor cell. The direct transfer of plasmids to S. typhimurium has been mostly realized only in the presence of the mobilizing plasmid, the transfer frequency being 1.0 X 10(-7) to 2.2 X 10(-4) per donor cell. S. typhimurium transconjugates show decreased virulence in both enteral and intraperitoneal infection of mice.

Animals↗
PubMed1984

[Relation of Salmonella typhi and Salmonella gallinarum auxotrophicity to the ability to grow on Simmons' medium].

A total of 9 S. typhi strains and 1 S. gallinarum strain isolated from clinical material are auxotrophic with respect to tryptophan. The growth of S. typhi is accelerated in a glucose- and tryptophan-containing minimal medium with cysteine and methionine added. S. typhi strains are incapable of using sodium citrate as the only source of carbon. S. typhi cannot grow on Simmons citrate agar as these organisms are auxotrophic with respect to tryptophan and incapable of using sodium citrate as the only source of carbon, and S. gallinarum cannot grow on this medium as they are auxotrophic with respect to tryptophan.

Citrates↗
PubMed1983

Criteria for the standardization of Salmonella mutagenicity tests: results of a collaborative study. III. The influence of the composition and preparation of the minimal medium in the Salmonella mutagenicity test.

The influence of factors connected with the preparation of the minimal medium for the Ames test has been investigated. Faulty sterilization procedures can lead to the generation of toxic and/or mutagenic by-products in the minimal medium. Changes in histidine concentration affect not only the number of spontaneously arising colonies on the plate, but also the number of induced mutants. Although the number of spontaneous mutants increases slightly with increasing histidine concentration, the influence on the number of induced mutants depends on the nature of the mutagen tested.

Agar↗