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PubMedDate not supplied

Recanalization of a single functioning kidney.

For patients with renal artery stenosis, percutaneous transluminal angioplasty is generally the treatment of choice. This report describes the case of an elderly lady with type III aortoarteritis whose right renal artery was successfully recalized and stented. There was satisfactory improvement in renal function and blood pressure post-procedure, and at one-month follow-up.

Angiography↗
PubMed2006

High-frequency mechanical vibration to recanalize chronic total occlusions after failure to cross with conventional guidewires.

BACKGROUND: Crossing chronic total occlusions (CTO) of coronary arteries continues to challenge interventional cardiologists. A clinical study was undertaken in four European centers to examine the feasibility of using the new CROSSER system that utilizes high-frequency mechanical vibration to penetrate atherosclerotic plaque material to cross CTOs in patients where conventional guidewire techniques had failed. The objective of the study was to determine whether the CROSSER system could safely cross such CTOs. PATIENTS AND METHODS: A total of 55 CTO lesions in 53 patients were treated in two clinical phases: (1) Phase 1 feasibility study (30 CTOs), with a primary focus on device safety; and (2) Phase 2 pivotal study (25 CTOs) using an improved version of the device, with a primary focus on effectiveness. RESULTS: The primary endpoint of device efficacy and the secondary endpoint of clinical success were both 76% (19 of 25) in the pivotal study phase. No major adverse cardiac events of death, Q-wave myocardial infarction or target lesion revascularization (by either coronary artery bypass graft surgery or percutaneous coronary intervention) were observed through 30-day follow up. No coronary perforation or pericardial tamponade occurred. CONCLUSIONS: The CROSSER system is a safe device that can cross many occlusions after a conventional guidewire failure. With additional refinement and improvements to the device, this success rate could be further increased.

Adult↗
PubMed2005

[Results of endoscopic recanalization for inoperable cancer of the esophagus].

Patients with inoperable cancer of the esophagus were followed up for 1-3 years after a course of palliative endoscopic destruction of tumor. Residual growth occurred in 88.1% with an average stabilization period of 47 days. Among the unfavorable prognostic factors were partial decomposition of tumor, squamous-cell pattern, size of more than 9 cm, circular extension through the esophagus and stage III stenosis. With the aid of newly-developed methods of outpatient endoscopic destruction, 94.2% could eat throughout their survival period. Mean survival time was 5.6 months or 7.3 months in metastasis-free cases.

Adult↗
PubMedDate not supplied

Postinflammatory glomerular recanalization is established under the accommodation of transformed mesangial cells.

BACKGROUND: The relationship between mesangial cell proliferation and sclerosis has been studied using rat Thy-1.1 nephritis. The reconstruction of capillary lumina is essential for the repair of postinflammatory tissue damage in this type of glomerulonephritis. METHODS: We administered thalidomide or STI571 to Thy-1.1 nephritic rats. Thalidomide was intended to be a sup-pressor of capillary proliferation, and STI571, which is known to be a tyrosine kinase receptor inhibitor, was used for preventing mesangial proliferation. RESULTS: The thalidomide-treated group showed a significant increase of urinary protein on day 3. ED-1-positive cells stagnated longer and the matrix increase was delayed. STI571 caused suppression of mesangial proliferation, and microaneurysm remained longer than in the other 2 groups, which resulted in delay of glomerular capillary reconstruction. The number of alfa-SMA-positive cells appeared to be smaller in both the thalidomide- and the STI571-treated groups. CONCLUSIONS: Thalidomide had an effect in the early period of the experiment; however, there was no influence on the repair of glomerular capillary at the end. STI571 treatment, which inhibited proliferation of alfa-SMA-positive cells, seems to show that some degree of mesangial cell proliferation is necessary to reconstruct capillary structures and to regain glomerular function.

Animals↗
PubMed1991

[Roentgeno-endovascular dilatation and recanalization of the arteries in thrombosis and other occlusive diseases].

The authors analyze the results of 143 ++roentgeno-endovascular dilatations (RED) made in 89 patients during 1986-1990. RED of stenoses and occlusions of the iliac and femoral arteries over a length of less than 10 cm is feasible practically in all the patients. This intervention is safe and well tolerated by patients. As for RED of occlusions of the femoral arteries over a length of more than 15 cm beginning from the arterial ostium, the authors recommend that a popliteal access to the femoral artery be employed. Otherwise the passage of the occlusion area in the antegrade direction is impossible. At the same time in order to prevent thromboembolic complications, it is necessary to carry out intra- and postoperative anticoagulant therapy. Extended occlusions of the femoral arteries can be subjected to RED in cases where calcinosis of the arteries and thrombotic component are lacking in occlusion. RED of renal artery stenosis can be used as a method of choice in the treatment of vasorenal hypertension. RED is likely to be used for the management of stenoses of unpaired visceral arteries.

Adult↗
PubMed1991

[Rotacs: a device used in coronary and peripheral arterial recanalization].

The authors report their preliminary results with the Rotacs system in the reopening of chronic coronary artery occlusion by low-speed rotational angioplasty. This system improves the percentage of coronary recanalisation in cases where it is impossible to pass the guide wire alone. It seems to be an effective, low-cost complementary tool for the treatment of this type of lesion.

Angioplasty, Balloon↗
PubMed1991

[Interventional angiology in the area of the thigh. Percutaneous balloon dilatation, new procedures of recanalization, stents].

The major technique of interventional angiology of the arteries of the thigh is percutaneous balloon dilatation (angioplasty). In the case of short stenoses and occlusions, the primary results and long-term success of these techniques are very good. In order to be able to successfully treat long, highly calcified, eccentric and fresh lesions using the percutaneous approach, numerous new procedures have been developed. These include local fibrinolysis, aspiration of thromboembolic material, ablation of atherosclerotic plaques using an endovascular knife, the drilling open of occlusions, the use of the laser, and implantation of vascular endoprostheses.

Angioplasty, Balloon↗
PubMed1991

[Primary results of laser recanalization in the endovascular treatment of arterial stenosis and occlusion of the lower limbs. Apropos of 45 treated cases].

Forty-five lower limb arterial lesions were treated by Nd Yag laser angioplasty using 1.4 and 2 mm hybrid catheters in 31 patients. This population comprised 28 men and 3 women (average age 63.8 +/- 3 years) 20 were in Stage II, 5 in Stage III and 6 in Stage IV of Fontaine's classification. The arteriographic lesions were 22 occlusions with an average length of 12.3 cm and 23 stenoses averaging 87% luminal reduction a few millimeters long to a maximum of a string of stenoses. Seventeen of these lesions were very calcified. The stenoses were situated on the iliac artery (7 cases), superficial femoral artery (28 cases), popliteal artery (9 cases) and the tibio-peroneal artery (1 case). There were no fatalities or recourse to emergency surgery. All patients underwent complementary balloon dilatation. The immediate patency rate was 91% in stenotic and 72% in occlusive lesions. At one week, the patency rate for stenotic lesions was unchanged but it had fallen to 59% for occlusive lesions (arteriographic evaluation). Angioscopy was used 22 times: it was indissociable to laser angioplasty as it enabled diagnosis and controlled the result. The use of thermal laser with hybrid catheters (metallic window tip) in endovascular procedures is a safe and effective method of treating stenosis and occlusion of lower limb arteries.

Adult↗