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At least 937 records · Page 52Linked to original sources

Urinary tract infection in adolescent boys.

Clinical and laboratory features of 21 adolescent males with urinary tract infections were studied. Sixty-seven percent were symptomatic and 80% revealed abnormalities on initial urinalysis. Forty-eight percent showed structural anomalies of the urinary tract. Recurrences were observed only in those having abnormalities of the urinary tract.

Adolescent↗

Urinary beta 2 microglobulin in upper and lower urinary-tract infections.

Beta 2-- microglobulin excretion in 24 h urine collections and beta2- microglobulin clearance were significantly increased in patients with upper-urinary-tract infections, but beta 2- microglobulin clearance and excretion were normal in patients with cystitis. Beta 2-microglobulin estimation may be used to distinguish between upper and lower urinary-tract infections, except when pre-existing tubular damage is present. Voided urine must have a pH above 6 . 0, since beta 2- microglobulin is rapidly degraded in the bladder at low pH.

Aged↗

Glycosaminoglycans and struvite calculi.

Glycosaminoglycans (GAGs) are suspended in urine and are present on tissue surfaces in the urinary tract. Consequently, they have the potential to influence any pathological disorder in this environment, including urinary tract infections by Proteus mirabilis and struvite (NH4MgPO4.6H2(0)) urolithiasis. Although GAGs, suspended in urine, may inhibit the formation of other types of calculus minerals, no such effect has been reported in struvite calculi. Nevertheless, GAGs are a major component of the organic matrix of all types of urinary calculi. In contrast, there is evidence that the GAG layer on the bladder surface may act as a defence mechanism against infection by inhibiting bacterial adhesion. More studies are needed to elucidate fully the role of GAGs in urinary infections and struvite urolithiasis.

Glycosaminoglycans↗

[Wound care management of ulceration in a palliative care patient].

The wound care management of a palliative care patient with sinusitis pinoidalis is documented. The treatment is validated by the expert's opinion. There is only little evidence-based treatment of such a lesion. In our experience, photo documentation is helpful in decision-making during the treatment process. In addition, healing of larger defects seems to improve upon frequent and extensive liquid cleansing.

Abscess↗

Near-fatal complications of tracheotomy infections and their prevention.

Infectious complications of tracheotomy range from minor to potentially fatal. Three cases are presented: clavicular osteomyelitis; innominate artery blowout with mediastinitis; and the first reported case of necrotizing fasciitis involving the chest wall related to tracheotomy infection. All patients were debilitated, with one diabetic and another steroid-dependent. Infectious sequelae occurred as late as 8 weeks following tracheotomy. The mechanism, treatment, and prevention of tracheotomy infections are reviewed. Indications for the creation of a permanent but reversible tracheostome should be expanded to prevent infections in debilitated or immunosuppressed patients in whom decannulation is unlikely.

Fasciitis↗

Different binding specificities of P. mirabilis compared to E. coli.

The target cell specificities of P. mirabilis and E. coli strains were compared using human urinary tract epithelial cells and erythrocytes from human, guinea pig, sheep, ox and horse blood. P. mirabilis strains agglutinated the erythrocytes both in mannose-resistant and mannose-sensitive patterns. No relation was, however, found between hemagglutination and adhesion to uroepithelial cells. This is in contrast to E. coli where uroepithelial cell attachment is paralleled by mannose-resistant agglutination o human erythrocytes. The difference in receptor recognition between P, mirabilis and E. coli was further indicated by the fact that P. mirabilis strains attaching to human uroepithelial cells did not agglutinate guinea pig red cells coated with globotetraosylceramide, acting as a receptor for E. coli on human uroepithelial cells erythrocytes.

Animals↗

Ciprofloxacin in the treatment of chronic bacterial prostatitis: a prospective, non-comparative multicentre clinical trial with long-term follow-up. The German Prostatitis Study Group.

The efficacy and safety of ciprofloxacin 500 mg bd for 28 days were assessed in 65 adult males with symptomatic bacterial prostatitis, from eight centres in Germany. Urine and prostatic secretions were obtained for culture. Clinical signs and symptoms were evaluated at 12-18 days during treatment, end of treatment (4-9 days post-treatment), and 1, 3, 6 and 9 months post-treatment. Safety was monitored during and at the end of treatment. E. coli was the most frequent pathogen causing infection (35/62) and Enterococcus faecalis the second most frequent (13/62). The combined bacteriological response by patient determined at return visits 4-9 days post and 1 month post-treatment, respectively, was eradication 48/54 (88.9%), persistence 3/54 (5.6%), eradication with recurrence 1/54 (1.9%) and eradication with reinfection 2/54 (3.7%). The clinical response at 1 month post-treatment was resolution 53/54 (98. 1%) and 1/54 (1.9%) failure. The rates for continued eradication in the extended follow-up were 32/39 (82.1%) after 3 months, 26/34 (76. 4%) after 6 months and 13/22 (59.1%) after 9 months. Nineteen patients experienced at least one adverse event. In two patients the trial was prematurely discontinued due to adverse events.

Adolescent↗

Combined coliform and anaerobic infection of the lacrimal sac.

A case is reported of combined coliform and anaerobic bacterial infection of the lacrimal sac, a condition of which there is only one other published case report. In addition, a literature review is presented of the bacteriology of acute dacryocystitis as it applies to this case. Recommendations for the microbiological investigation and management of acute dacryocystitis are made.

Acute Disease↗