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[Incidence of the form and caliber of urethral resistance. Evaluation for a normal masculine urethra and in cases of obstruction due to prostatic hypertrophy].

Certain forms of benign prostatic hypertrophy are associated with a reduction of the calibre of the prostatic urethra of the median lobe, a defect of infundibulisation of the bladder neck and a dilated appearance of the bulbar urethra. The objective of this study was to verify whether hydrodynamic arguments could be used to confirm the concept that defective infundibulisation of the bladder neck is directly responsible for an obstructive syndrome or via a reduction in the calibre of the bladder neck orifice. More generally, this study was designed to quantify the distribution of resistance to flow along the normal urethra and to define the role of cervicoprostatic and urethral deformities in the obstruction associated with benign prostatic hypertrophy. Urodynamic studies are unable to answer this question, as the instantaneous urethral resistance is evaluated globally by the Pressure-Flow relation. The authors performed morphological analysis to divide the urethra into simple hydraulic segments for which the corresponding pressure drop coefficients were calculated. These coefficients constitute an approach to segmental resistance to flow and can be used to quantify changes in shape observed on voiding urethrography or ultrasonography. Digital analysis of voiding urethrographies showed that, under normal conditions, urethral resistance was regularly distributed along the urethra and essentially depended on friction of the urethral wall. In the case of benign prostatic hypertrophy, even with a median lobe, the increase in the pressure drop coefficients was due to a reduction in the calibre of the bladder neck orifice and prostatic urethra. Cervical deformities appeared to be minimally obstructive, according to urodynamic parameters, if they were not associated with a reduction in the calibre of the bladder neck orifice.

Evaluation Studies as Topic↗

[Enzyme-induced masculinization].

Contribution of two cases of congenital adrenal hyperplasia by blockade in the 21-hydroxylase enzyme synthesis. Diagnosis was reached from the clinical signs and symptoms (virilization syndrome), and was confirmed by radiological and laboratory tests. Hormone treatment was done with hydrocortisone and fludrocortisone, but surgical correction of external genitalia was required to improve cosmetic appearance.

Adolescent↗

Healthy masculinity starts in boyhood.

Addressing the crisis in men's health is more subtle than lecturing on lifestyle, diet or safety. Men's risk-taking behaviour is driven by deep unhappiness with life. Many of the mental health problems of men may be due to the estrangement between fathers and sons since the industrial revolution and the lack of self-worth this has created. Practical steps such as men's group are being fostered by GPs and others around Australia.

Adolescent↗

[Preservation of masculine sexual functions after treatment for abdominal aortic aneurysms].

UNLABELLED: Preserving sexual function is an important objective in the treatment of aneurysms of the abdominal aorta in men. METHOD: Two groups of patients with normal sexual function were operated for aneurysms of the abdominal aorta. In group 1 (n = 22) a small opening in the infra-renal aorta was made for insertion of an aorto-bi-iliac prosthesis; in 4 of them, the aneurysm was not opened but simply excluded. In group 2 (n = 22), the aorta was opened longitudinally for insertion of an aorto-aortic tube. RESULTS: Sexual function was totally abolished after operation in 9% of the patients in group 1 and in 36% of those in group 2. Sexual functions were totally preserved in 50% of the patients in group 1 and in 36% of those in group 2, but the differences were not statistically significant. CONCLUSIONS: 1) It is not always possible to guarantee maintained sexual function after operation for aneurysms of the abdominal aorta and the patients should be advised thereto; 2) aortobi-iliac prostheses with limited opening of the aorta in the upper part of the aneurysm or exclusion of the aneurysm led to a higher rate of preservation than aorto-aortic tubes with total opening of the aneurysm and should be preferred in men with normal sexual function.

Aortic Aneurysm, Abdominal↗

[Surgical management of masculine trassexualism].

The authors report on the first Hungarian case of sex-transforming operation. They present details of the social history and management of their case leading up the decision for surgery. Preoperative assessment and medication, operation technique and postoperative care are also described in detail. The case report highlights the difficult ethical and legal issues which have to be considered when such surgery is requested. Following a series of in-depth psychological, gynaecological, urological and forensic consultations that had been carried out in order to be convinced about the patients's determination for undergoing sex-transforming operation, the authors were granted legal and professional license by the Hungarian Medical Research Council to carry out the procedure. Two years after the operation, the patient commented on her full satisfaction with the care he had received.

Adult↗

Masculinizing and feminizing syndromes caused by functioning tumors.

Steroidogenic tumors are derived from cells of male and female reproductive tracts, adrenal glands, central nervous system, and, to a lesser degree, from the liver and pituitary gland. The symptoms caused by these tumors are related to their secretory products. Because enzymatic pathways are shared by both adrenal- and gonadal-derived tissues, and the conversion of some of these steroids occurs in the adipose tissue, positive identification of many lesions cannot be based on peripheral blood hormone levels alone, but require complex protocols to improve diagnostic accuracy. Furthermore, these tumors often are smaller than the size limit of conventional imaging modalities and thus demand more precise imaging techniques. Although diagnosis and localization may be challenging, the rewards of a positive prognosis, with complete reversal of symptoms, are more likely to occur with early detection and treatment. This article is a review of the clinical syndromes associated with pediatric steroidogenic tumors; suggested strategies to facilitate their diagnosis, localization, and treatment are provided.

Adrenal Gland Neoplasms↗