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Vaginal physiology during menstruation.

We studied 18 young healthy women on the second, fourth, and 14th day of their menstrual cycle. Vaginal fluid was collected for measurement of oxygen and carbon dioxide tension (PO2 and PCO2) and specimens were collected for bacteriologic examination. The vaginal pH was measured at four different sites and the redox potential was measured in the top of the vagina. Staphylococcus aureus was found in three women. The PO2 ranged from 0 to 77 mm Hg on day 2; 0 to 76 mm Hg on day 4; and 0 to 53 mm Hg on day 14. The mean PCO2 (+/- SE) was 46 +/- 2 mm Hg on day 2; 62 +/- 4.5 mm Hg on day 4; and 50.6 +/- 8.5 mm Hg on day 14. The mean vaginal pH (+/- SE) was significantly higher on day 2 (6.6 +/- 0.3) compared with day 4 (5.3 +/- 0.3) and day 14 (4.2 +/- 0.2). The redox potential was significantly higher on day 14 compared with day 2 and day 4. No differences were found in values of women who took birth control pills and those of the women who did not.

Adult↗

Total and free testosterone and total and free 17 beta-oestradiol in normally menstruating women.

Estimations of plasma total and free testosterone (T) as well as of total and free 17beta-oestradiol (E2) have been performed in 6 normal women throughout the menstrual cycle. The plasma total T levels showed a small but significant cyclical variations, with significantly increased values around the midcycle (p less than 0.001). The pattern of free T during the cycle was similar to total T. Regarding total plasma E2, two typical peaks occurred, which were also observed in plasma free E2. Changes in testosterone-17beta-oestradiol binding globulin have not been detected throughout the menstrual cycle.

Estradiol↗

Social factors in the psychology of menstruation, birth, and menopause.

Information about possible social influences on the psychology of reproduction, supplemented by a clinical understanding of the psychodynamics of the individual and scientific knowledge about the effects of hormones on behavior, provides insight into the experience of a particular woman in a particular social milieu. Such insight is an appropriate basis for effective treatment of many of the clinical problems in the area of psychosomatic obstetrics and gynecology.

Attitude↗

Correlation between glycemic control and menstruation in diabetic adolescents.

OBJECTIVE: To determine if a correlation exists between the degree of glycemic control in insulin-dependent diabetic adolescents and menstrual regulation. STUDY DESIGN: A retrospective review of charts of diabetic girls aged 10-18 was performed. Office visits were scheduled every three to six months, at which time pubertal development, menstrual function, growth and diabetic control, including hemoglobin (Hgb) A1C, and complications were assessed. Forty-six patients were eligible for data analysis. Descriptive and inferential statistics, including chi 2 and Student t tests, were applied. RESULTS: Thirty-seven (81%) patients had regular menstrual cycles, and nine (19%) had menstrual disturbances, including secondary amenorrhea (one), oligomenorrhea (seven) and primary amenorrhea followed by oligomenorrhea (one). There were two pregnancies. Six patients used hormonal contraception but none for menstrual regulation. There was a statistically significant difference (P < .05) in mean Hgb A1C concentrations between those with menstrual disturbances (11.4) and those with regular menses (9.7). As Hgb A1C values increased, the percent of patients with menstrual disturbances increased, becoming statistically significant when the Hgb A1C was > 10 (odds ratio 7.3, 95% confidence interval 1.5-35.6). There was no difference (P > .05) between the two groups with respect to age at menarche (156 vs. 152 months), age at onset of diabetes (144 vs. 108 months) and interval between diabetes onset and menarche (54 vs. 41 months). There were no patients in either group with diabetic retinopathy or nephropathy. Four patients were hypertensive, but there was no statistically significant difference (P > .05) between groups. CONCLUSION: Tighter glycemic control, as measured by Hgb A1C concentrations, corresponded to improved menstrual regulation in adolescent insulin-dependent diabetics.

Adolescent↗

[Pneumothorax during menstruation: a case report].

Endometriosis is a condition where endometrial glands lie outside the uterine cavity. The underlying pathophysiological mechanism remain unclear. Pelvic localizations are common but thoracic are possible. Catamenial pneumothorax is a clinical variant of spontaneous pneumothorax. The 39 years old women with catamenial pneumothorax is reported. Patient suffered from endometriosis. Diagnosis was established on clinical grounds. After laparoscopy the danazol treatment was started.

Adult↗