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PubMed2006

Airway management by paramedics using endotracheal intubation with a laryngoscope versus the oesophageal tracheal Combitube and EasyTube on manikins: a randomised experimental trial.

INTRODUCTION: The EasyTube, which is constructed in a similar way to the Combitube, is a recently introduced alternative to tracheal intubation for airway management in emergency medicine. OBJECTIVE: To determine if there is a difference in rate of, and time to, successful airway placement and ventilation using tracheal intubation, Combitube and EasyTube. METHODS: Twenty-six paramedics, trained in tracheal intubation received additional training in the use of the Combitube and the EasyTube. Each participant performed all three methods twice in random order on a manikin. Time to successful ventilation (presented as mean and standard deviation) and success rate were recorded. RESULTS: Mean time to successful ventilation was significantly longer for tracheal intubation (45.2 s (S.D.=15.8)) than for the Combitube (36.0 s (S.D. = 8.6)) p = 0.002 and the EasyTube (38.0 s (S.D.=15.3)) p = 0.023 with no difference between the latter (p = 1.000). Success rate for the Combitube and EasyTube combined (103/104) was significantly higher than for tracheal intubation (45/52) with odds ratio 16.0 (95% CI: 1.9-134); p = 0.002. CONCLUSION: For paramedics tested on manikins placement success rate was higher with less time required for the Combitube and Easytube than for tracheal intubation with no differences between the Combitube and EasyTube.

Adult↗
PubMed1997

Determinants of longer duration of endotracheal intubation after adult cardiac operations.

BACKGROUND: Poor pulmonary reserve is a risk factor that is used to exclude some patients from major operations. However, the value of routine spirometry in patients undergoing cardiac operations has not been widely evaluated. METHODS: The outcomes of 586 consecutive adult patients undergoing cardiac operations were reviewed retrospectively to assess predictors of longer duration of endotracheal intubation. RESULTS: By univariate analysis, congestive failure (p < 0.001), cardiomegaly (p = 0.002), recent myocardial infarction (p = 0.039), priority of operation (p = 0.005), previous cardiac operation (p < 0.001), and renal insufficiency (p = 0.002) increased the risk of longer endotracheal intubation. Spirometry (forced vital capacity, forced expiratory volume at 1 second, the ratio of forced expiratory volume at 1 second to forced vital capacity) did not correlate with longer endotracheal intubation. Perioperative complications, such as myocardial infarction (p < 0.001), coma, reexploration for bleeding, and reduced cardiac output (p < 0.001 each), correlated with longer duration of intubation. By multiple regression, priority of operation (p = 0.03), congestive failure (p = 0.02), and previous cardiac operation (p = 0.005) among preoperative risks and bleeding, reduced cardiac output, stroke, coma, and MB fraction of creatine kinase released postoperatively (p < 0.001 each) predicted longer duration of endotracheal intubation. CONCLUSIONS: Postoperative cardiac function and the occurrence of complications are more significant than preoperative pulmonary function in determining the duration of endotracheal intubation after cardiac operation. Routine spirometry is probably unnecessary for most adult cardiac patients.

Adult↗
PubMed1996

Prospective assessment of colonoscopic intubation skills in trainees.

INTRODUCTION: The American Society for Gastrointestinal Endoscopy recommends a minimum of 100 supervised colonoscopies prior to assessment of technical competence. To establish a measurable standard for competence and to assess this recommendation, performance of colonoscopies at a university hospital was studied. METHODS: Colonoscopic preparation, surgical history, medication usage, technical maneuvers, extent of colon intubated, success rate, and cecal intubation time were prospectively monitored for first-year trainees, second-year trainees, and attendings. RESULTS: Excluding patients with poor preparations or colonic resections, 496 colonoscopies were studied. First-year trainees (n = 5) required attending assistance in 73 of 79 (92%) procedures. Second-year trainees (n = 7), who had performed a mean of 123 colonoscopies prior to the study, required attending assistance in 37 of 102 (36.3%) procedures. Attendings (n = 7) successfully intubated the cecum in 297 of 315 (94.3%) colonoscopies in a median time of 10.5 minutes. Second-year trainees were less successful than attendings in cecal intubation (success rate = 84%, p < 0.05), and required more time (median = 14.5 minutes, p < 0.01). More technical maneuvers were performed, and a lesser extent of colon was intubated, during trainee colonoscopies. CONCLUSIONS: We propose a 90% success rate and a median cecal intubation time of less than 15 minutes as reasonable standards for measuring technical competence. Trainees do not achieve this standard after the performance of 100 supervised colonoscopies.

Cecum↗
PubMed1984

Nasotracheal intubation in the neonate: physiologic responses and effects of atropine and pancuronium.

Thirty infants with birth weights from 580 to 3450 gm (25 to 40 weeks gestation) were prospectively studied during nasotracheal intubation. The infants were randomized to receive atropine 0.01 mg/kg, atropine 0.01 mg/kg plus pancuronium 0.1 mg/kg, or no medication (controls) prior to intubation. There was a significant decrease in transcutaneous PO2 (27.3 torr, P less than 0.02), associated with significant increases in mean arterial blood pressure (57%, P less than 0.01) and intracranial pressure (mean increase 18.9 cm H2O, P less than 0.01) with intubation in all three groups of infants. Only in control infants and infants receiving atropine was there significant decrease in heart rate (52.2 and 36.2 bpm, respectively, P less than 0.01) during intubation. Control infants experienced a significantly greater decrease in heart rate and demonstrated the lowest mean heart rate, compared with the other two groups. Pancuronium plus atropine was associated with lesser increases in intracranial pressure and with the least changes in heart rate in response to intubation. There was no significant difference between the groups for changes in systemic blood pressure or transcutaneous PO2. Further studies are required to determine the clinical consequences, if any, of these responses, and the use of pretreatment in the neonate requiring intubation.

Apnea↗
PubMed1991

A disposable end-tidal CO2 detector to verify endotracheal intubation.

STUDY OBJECTIVE: We compared the performance of the Fenem FEF end-tidal CO2 detector with the TRIMED capnometer to verify endotracheal intubation. DESIGN: The FEF indicates the presence of CO2 by the color change of a chemically treated indicator; the TRIMED uses infrared technology. Both devices were used during 60 intubations. SETTING: Intubations during in-hospital emergency situations outside of the operating room were studied. TYPE OF PARTICIPANTS: Adult patients undergoing intubation for respiratory failure, CPR, and other airway protection situations were enrolled in the study. INTERVENTIONS: The TRIMED monitor and FEF detector were placed in series between the manual resuscitator and the patient's endotracheal tube adapter after endotracheal tube placement. MEASUREMENTS AND MAIN RESULTS: We defined the acceptable criterion for detection of CO2 as production of a positive signal within six manual resuscitator bag breaths. The TRIMED met this criterion in 58 of 60 patients (sensitivity, 0.97) and the FEF met this criterion in 59 of 60 patients (sensitivity, 0.98). A paired t test showed no statistically significant difference in performance between the two devices. In five of nine cases of intubation during CPR, the color change of the FEF was described as "subtle." In one CPR case, a positive signal was not obtained by either device. CONCLUSION: We conclude that the performance of the FEF CO2 detector is equal to that of the TRIMED monitor for verification of endotracheal intubation in nonCPR situations. Interpretation of FEF color changes during CPR should be approached with caution until further studies using the FEF during CPR are completed.

Adult↗
PubMed1993

Continuous pulse oximetry during emergency endotracheal intubation.

STUDY OBJECTIVE: To determine whether continuous pulse oximetry improves the recognition and management of hypoxemia during emergency endotracheal intubation. DESIGN: A prospective, serial 14-month study. SETTING: Emergency department, Level I trauma center. TYPE OF PARTICIPANTS: All adult patients requiring emergency intubation for whom data collection would not compromise patient care. INTERVENTIONS: All samples were obtained from a finger site at a five-second sampling interval and stored in computer memory. Patients were intubated by the nasotracheal or orotracheal route. MEASUREMENTS AND MAIN RESULTS: One hundred ninety-one consecutive adult patients qualified for the study and 211 intubation attempts were analyzed. Hypoxemia (O2 saturation, less than 90%) occurred during an intubation attempt in 30 of 111 nonmonitored versus 15 of 100 monitored attempts (P < .05), and the duration of severe hypoxemia (O2 saturation, less than 85%) was significantly greater for nonmonitored attempts (P < .05). CONCLUSION: Continuous pulse oximetry monitoring reduces the frequency and duration of hypoxemia associated with emergency intubation attempts.

Emergencies↗
PubMed1982

Succinylcholine for endotracheal intubation.

In the emergency department at Hennepin County Medical Center, succinylcholine has been used to assist difficult intubations since March 1, 1979. In this report, the first 48 cases are reviewed. In these 48 patients, complete relaxation allowing endotracheal intubation was achieved in 42. Forty of the 42 patients intubated suffered no adverse effects. One patient vomited, delaying intubation, and another developed transient asystole. Six of 48 patients were not successfully intubated after succinylcholine; five of these six subsequently required cricothyrotomy. Inadequate dose, improper technique of administration, foreign material obscuring airway, and idiosyncratic reactions were thought to be reasons for failure. When properly administered, succinylcholine can be used to facilitate difficult intubations in the emergency department with an acceptable incidence of adverse effects or failures.

Adult↗
PubMed1984

Effect of varied training techniques on field endotracheal intubation success rates.

A pool of 146 mobile intensive care unit paramedics was divided into four equal groups and trained in the technique of direct laryngoscopic endotracheal intubation of cardiac arrest or deeply comatose patients. Group 1 was selected from supervisors and crew chiefs and trained as preceptors. The remaining paramedics were assigned to three other study groups. Groups 1 and 2 were trained with a didactic presentation followed by manikin practice, an animal laboratory exercise, and operating room experience. Group 3 had no OR experience; Group 4 had only didactic/manikin training. Intubations were observed by preceptors on scene. During the study period of 27 months, 689 of 763 patients (90.3%) were successfully intubated by 122 paramedics. While results suggest variation in skill levels according to training group (Group 1, 92.4%; Group 2, 87.6%, Group 3, 83.3%; Group 4, 76.9%), statistical analysis allowing for the variables of seniority and number of intubations performed by personnel failed to reveal differences in groups attributable to training programs. Complication rates were relatively low for all groups, the most common being prolonged intubation attempts. A significant improvement in the skill was seen as the study progressed when groups are pooled and compared. The findings suggest that endotracheal intubation of deeply comatose or cardiac arrest patients is a field procedure that can be performed safely and skillfully by well-monitored paramedical personnel. Operating room or animal laboratory experience may increase initial success levels, but these factors do not appear to greatly influence eventual performance or incidence of complications of the procedure.

Allied Health Personnel↗
PubMed1986

Ventricular fibrillation during orotracheal intubation of hypothermic dogs.

Physical manipulation of the hypothermic patient is well known to cause ventricular fibrillation. Careful review of the literature fails to demonstrate a true temporal relationship between orotracheal intubation and ventricular fibrillation (VF) when acceptable temperature-corrected arterial blood gases have been obtained. Eleven mongrel dogs were anesthetized and cooled, with orotracheal intubation and extubation performed every two degrees centrigrade, starting at 27 C. Ventilator setting were adjusted to maintain normal pH according to arterial blood gases drawn every two degrees and corrected for temperature. There was only one episode of VF during 42 intubations performed at temperatures less than 28 C (2.38%). There were eight separate episodes of spontaneous VF unrelated to intubation in five dogs. Four of these five with spontaneous VF were resuscitated with countershock only, further cooled, and reintubated an additional 11 times without a single episode of VF during intubation. Our data suggest that the incidence of VF during intubation in the hypothermic patient is much less than previously described, provided that normal pH is maintained and hypoxemia is corrected.

Animals↗
PubMed1988

The effect of axial traction during orotracheal intubation of the trauma victim with an unstable cervical spine.

Axial (in-line) traction is recommended as a stabilizing maneuver during orotracheal intubation of a trauma victim with a potential cervical spine injury. There are no published data demonstrating the safety of this technique in trauma patients with an unstable cervical spine. In our study, 17 victims of blunt traumatic arrest had radiographic analysis of the cervical spine during orotracheal intubation, with and without axial traction. Four (24%) had unstable injuries, which included a C6-7 fracture dislocation, a Hangman's fracture, and two atlanto-occipital dislocations. Axial traction during oral intubation in these victims resulted in a mean distraction at the fracture site of 7.75 mm. Axial traction produced 4 mm of posterior subluxation in the C6-7 fracture dislocation, demonstrating that axial traction alone may result in subluxation, as well as distraction. This depends on the direction of the traction force and integrity of surrounding tissues. We recommend that trauma patients requiring intubation prior to a complete examination and radiographic analysis of the cervical spine be nasotracheally intubated without axial traction, and that the head and neck be stabilized in the neutral position. If a contraindication to nasotracheal intubation exists, a cricothyroidotomy should be performed.

Emergencies↗
PubMed1989

Medical student retention of intubation skills.

Medical students are trained in airway management by endotracheal intubation in most medical schools. Unfortunately, little data exist examining retention, and no data exist that actually break down the steps of intubation to determine where students encounter problems. We studied 64 medical students trained to intubate as part of an American Heart Association advanced cardiac life support course and their performance two to three months after training. The rate of successful intubation (confirmed by visualization) was 70 +/- 12%. The most frequent errors during intubation were failure to check the light before intubation, use of the teeth as a fulcrum, and failure to check the cuff on the endotracheal tube. Knowledge of the most common errors will allow instructors to place greater emphasis on those areas during the initial instruction period with a focus on decreasing their occurrence in the future.

Clinical Competence↗
PubMed1996

Field intubation of trauma patients: complications, indications, and outcomes.

Neither the success nor the complication rate for field intubation of trauma patients is known with any certainty. A retrospective audit of 94 severely injured patients who required field intubation was undertaken. Fifty percent (13 of 26) of survivors and 67% (37 of 71) of nonsurvivors were successfully intubated in the field (not significant). Mechanism of injury was similar in both groups, but survivors were younger (27 v 60 years, P= .049) and less critically injured, as reflected by their Injury Severity Scale scores, their Trauma Scores, and their field Glasgow Coma Scale scores (22.1 v 30.8, P = .0035; 7.7 v 4.2, P < .0002; and 6.3 v 3.3, P < .0001). When compared with previously published studies of medical patients with cardiac arrest, the success rate was lower in our trauma patients. When compared with patients having similar injuries intubated at the trauma center, field intubation was three times more likely to be associated with the development of nosocomial pneumonia than was hospital intubation.

Emergency Medical Services↗
PubMed1997

Optimization of glottic exposure during intubation of a patient lying supine on the ground.

Two methods of endotracheal intubation of patients lying on the ground were compared for ease and speed of intubation and minimization of complications in a crossover study of prehospital-oriented emergency physicians. Intubation of a mannequin was attempted by the physicians in either a left lateral decubitus (LLD) position or a kneeling (K) position, followed by the alternate position. The LLD position afforded more rapid intubation, better glottic visualization, and less dental trauma. Eighty-seven percent of physicians completely visualized the glottis in the LLD position, versus 33% of the K position group. Intubation times were 10.5 versus 14.6 seconds in the LLD and K positions, respectively (P < .001). The LLD position is a more effective position (in a mannequin model) than the K position for intubation of patients found lying on the ground, a frequent situation in prehospital care.

Cross-Over Studies↗
PubMed1992

[Perforation of the esophagus during attempted endotracheal intubation].

A case is reported of oesophageal perforation which occurred during an attempt to carry out endotracheal intubation. A 54-year-old female patient was scheduled for mastectomy. She had no clinical features likely to predict a difficult endotracheal intubation. After induction with thiopentone, phenoperidine and suxamethonium, three attempts were made to carry out tracheal intubation with a Mallinckrodt Lo-pro tube, internal diameter 7.5 mm. During the third attempt, the oesophagus was accidentally intubated. The diagnosis was made before any insufflation was carried out. Another anaesthetist took over, and intubated the patient. At that time, there was left-sided cervical emphysema which quickly spread. An oesophageal perforation was suspected, and the patient was given 500 mg of metronidazole and 1 g of cefotetan. Postoperatively, the antibiotics were continued, and the patient had nothing by mouth. Oesophagography showed a posterior fistula in the upper third. Conservative treatment was continued until the seventh day, when another oesophagography was carried out. This showed that the perforation had completely healed. This rather rare complication of endotracheal intubation may have a poor prognosis if it results in mediastinitis. The diagnosis and prognosis of this complication and its treatment, whether conservative or surgical, are discussed.

Esophageal Perforation↗
PubMed1991

[Effects of urapidil on the cardiovascular response to intratracheal intubation].

The effects of urapidil on the haemodynamic response to endotracheal intubation were compared to that of placebo in two groups of 25 patients scheduled for general surgery. Normal saline solution or 0.4 mg.kg-1 urapidil were injected 3 min before induction of anaesthesia with 3 micrograms.kg-1 fentanyl, 0.3 mg.kg-1 etomidate and 0.1 mg.kg-1 vecuronium. Blood pressure (Pasys, Padia, Pa) and heart rate were measured continuously by servoplethysmomanometry before giving the test drug (T0), at the time when the lowest blood pressure was recorded during the three minute period between giving the drug and induction (T1), at the time when the lowest blood pressure was recorded during the three minute period between induction and endotracheal intubation (T2), at the time when the highest blood pressure was recorded immediately after intubation (T3), three minutes after intubation (T4), five minutes after intubation (T5), and at the time when the lowest blood pressure was recorded after surgery had been started (T6). It was planned to give a 25 mg urapidil dose to any patient, from either group, who had a Pasys greater than 200 mmHg for more than 60 sec. Giving urapidil lowered Pasys (T1) by 16%, whilst heart rate increased by 12%. The blood pressure peak due to endotracheal intubation was lower in those patients who had been given urapidil than in the placebo group (T3; p less than 0.05). Six patients in the latter group required the 25 mg urapidil dose, versus 2 in the urapidil group. The preventive effects of urapidil seem to be similar to those obtained with other antihypertensive agents.(ABSTRACT TRUNCATED AT 250 WORDS)

Adrenergic alpha-Antagonists↗
PubMed1987

[Conditions of intubation with vecuronium using a priming principle].

Different protocols based on the priming principle have been proposed so as to enable rapid tracheal intubation with vecuronium. The conditions of such an intubation have been assessed in 47 ASA I or ASA II patients, with an empty stomach, using a priming dose of 0.01 mg X kg-1, followed by a second injection of 0.1 mg X kg-1 after a short interval of 4 min. An intubation score was defined using a nerve stimulator (Relaxograph Datex), by measuring the twitch in comparison with a reference value, as well as time before intubation for four groups of patients. Good intubation scores with a twitch approaching 50% was obtained in all and, in the same way, for a fifth group of patients, intubated in an arbitrary manner 60 s after the second dose of vecuronium. These results can be compared with those obtained by other authors using a different protocol. Nevertheless, this method does not match perfectly that of suxamethonium. Taking into account the side-effects and above all the inhalation risk existing after a priming dose, is it opportune to use this technique for the anaesthesia of a patient with a full stomach?

Adult↗
PubMed1995

[Endotracheal intubation under propofol with or without vecuronium].

OBJECTIVE: In order to test the hypothesis that under the association propofol-alfentanil-IV lidocaine the trachea could be intubated easily without an additional muscle relaxant, this study compared the intubation conditions when this association was combined or not with vecuronium. STUDY DESIGN: Randomized comparative trial. PATIENTS: The study included 152 young adults classified as ASA physical class I and Mallampati presentation grade 1, randomly allocated either into Vecu+ group or Vécu0 group, depending on whether vecuronium was co-administered or not. METHODS: All patients received midazolam 0.05 mg.kg-1 i.v., one minute before induction. Those of group Vecu0 were given successively within two minutes: alfentanil 0.03 mg.kg-1, lidocaine 1.5 mg.kg-1 i.v. and propofol 2.5 mg.kg-1. Patients of group Vecu+ received similar doses of alfentanil and propofol as well as vecuronium 0.08 mg.kg-1. The endotracheal tube was inserted one minute after induction in the patients of Vecu0 group, and after three minutes in those of the Vecu+ group. During intubation, scores of mouth opening, glottis opening and coughing were established, in order to assess intubation conditions. RESULTS: Similar convenient intubating conditions were obtained in both groups (in 97% of patients in Vecu+ group vs 95% of those in Vecu0 group). In the latter, the glottis opening was less pronounced. CONCLUSIONS: In young healthy adults, without anaesthetic risk (emergency, full stomach) and without foreseen difficult intubation, the endotracheal tube can be inserted in convenient conditions without a muscle relaxant, under the association propofol-alfentanil-lidocaine iv.

Adult↗
PubMed1997

[Tracheal intubation in prehospital resuscitation: importance of rapid-sequence induction anesthesia].

OBJECTIVE: To investigate complications of emergency endotracheal intubation (EEI), possibly facilitated by rapid-sequence induction, in the prehospital critical care setting: 1) the difficulty of intubation; 2) the cardiorespiratory consequences of intubation; 3) the relationship between the occurrence of complications and prognosis. STUDY DESIGN: Prospective non randomized, open study. PATIENTS: All patients treated over a 5-month period by a physician-manned ambulance service and requiring EEI. METHODS: Patients were allocated either in with cardiac arrest (CA) group or a group with maintained spontaneous circulation (SC). Difficulty of intubation was assessed by the number of attempts. RESULTS: Two hundred and twenty-four consecutive EEI were carried out by physicians (46%) and residents (38%) not trained in anaesthesia, anaesthetists (8%), or nurse anaesthetists (7%). Trachea was intubated after a maximum of three attempts in all patients. Success rate at the first attempt was 91%. It was 92% in CA patients (n = 76) and 90% in SC patients (P = 0.59). Anaesthetic induction, with (n = 112) or without (n = 12) succinylcholine, was used to facilitate 84% of intubations in SC patients. Complications occurred in 30 patients (20%). There was no relationship between the latter and hospital mortality, duration of ventilatory support, duration of stay in the intensive care unit. CONCLUSION: In this study, EEI in SC patients was frequently facilitated by rapid sequence induction and was associated with a high success rate at the first attempt, as in CA patients. Morbidity was low. All physicians involved in emergency airway management should be skilled in this technique.

Adolescent↗