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PubMed1997

Non-Hodgkin's lymphoma in HIV-positive and HIV-negative homosexual men in the San Francisco Bay Area: allergies, prior medication use, and sexual practices.

Lifestyle, sexual history, and medical history characteristics were analyzed as risk factors for non-Hodgkin's lymphoma (NHL) in a population-based case-control study of 1593 subjects with NHL and 2515 control subjects conducted in the San Francisco Bay Area between 1988 and 1995. The results for homosexual men, 312 with NHL and 420 control subjects, showed that HIV infection was associated with a 20-fold increased risk for NHL. Among HIV-positive homosexual men, after adjustment for other factors, those that were associated with a reduced risk for NHL were frequency of receptive anal intercourse between the ages of 20 and 29 (1 to 9 times: OR = 0.63; > or = 10 times: OR = 0.37; trend: p = 0.02), allergy to grass, hay, leaves, plants and pollen (OR = 0.35, CI = 0.19 to 0.64), number of bee or wasp stings (1 to 3 times: OR = 0.65; > or =4 times: OR = 0.56; trend: p = 0.07), use of Tagamet (cimetidine) for 4 consecutive weeks or longer (OR = 0.39, CI = 0.17 to 0.89), vaccination against influenza (OR = 0.41, CI = 0.23 to 0.74), and lifetime frequency of amphetamine use (1 to 19 times: OR = 0.59; > or =20 times: OR = 0.38; trend: p = 0.003). Among HIV-negative homosexual men, after adjustment for other factors, factors that were associated with NHL status were frequency of receptive anal intercourse between the ages of 20 and 29 (1 to 9 times: OR = 0.39; > or =10 times: OR = 0.20; trend: p = 0.001), nonmedication allergies (OR = 0.43, CI = 0.21 to 0.89), vaccination against poliomyelitis at <10 years (OR = 0.41, CI = 0.17 to 0.99), and having five or more siblings (OR = 3.6, CI = 1.7 to 7.7). An increased immunosuppressive effect of seminal fluid on sensitive rectal tissue and support from earlier work suggesting that HIV-related lymphomas may be outgrowths of antigen-driven B cells provide a possible mechanism for the results of this study. The role of allergic reactions in NHL is likely to be complex and may be related to B-cell differentiation. These associations may provide insight into an antigen-driven process early in lymphomagenesis.

Adult↗
PubMed1975

The elusive homosexual: a reply to Stone and Schneider.

In a rebuttal of the Stone and Schneider validation study of the Wheeler signs of homosexuality in the Rorschach, it was argued that (a) homosexuality is not a proper clinical diagnosis, (b) homosexuals do not differ in psychological functioning from hetereosexuals, and (c) the Wheeler signs represent an atomistic approach of use only to those defensive clinicians unwilling to encounter the unique character of their clients.

Journal Article↗
PubMed1999

Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men. Multicenter AIDS Cohort Study (MACS).

BACKGROUND: Combination antiretroviral therapy including protease inhibitors (combo+PI) is effective in suppressing systemic viral load in HIV infection, but its impact on HIV-associated cognitive impairment is unclear. OBJECTIVE: To determine whether psychomotor speed, a sensitive measure of impairment in HIV dementia, improves with combo+PI compared with other antiretroviral treatments. METHODS: A total of 411 HIV-seropositive (HIV+) homosexual men (with longitudinal neuropsychological testing) in the Multicenter AIDS Cohort Study and, in a separate analysis, 282 HIV+ homosexual men with psychomotor slowing at baseline were classified by treatment into four groups: antiretroviral naive (no antiretroviral medication treatment), monotherapy, combination antiretroviral therapy without protease inhibitors (combo-noPI), and combo+PI. We compared longitudinal performance on three tests of psychomotor speed: the Grooved Pegboard (GP) (nondominant and dominant hands), Trail Making Test B, and the Symbol Digit Modalities Test (SDMT). RESULTS: Relative to antiretroviral-naïve and monotherapy participants, on the GP nondominant hand test, combo+PI participants with abnormal baseline neuropsychological testing showed improved performance (difference = +0.63 standard deviation [SD], p = 0.02). For the SDMT, both combo+PI participants (difference = +0.26 SD, p = 0.03) and combo-noPI participants (difference = +0.29 SD, p = 0.01) with abnormal baseline neuropsychological testing improved compared with antiretroviral-naïve and monotherapy groups. CONCLUSION: Combo+PI and combo-noPI are associated with improved psychomotor speed performance in HIV+ homosexual men with abnormal neuropsychological testing.

Adult↗
PubMed1990

Sexually Transmitted Diseases in Homosexual Youth.

The prevalence of sexually transmitted diseases (STDs) in homosexual populations is due to a complex interrelationship of host and pathogen factors. This chapter explores the risk factors, epidemiology, microbiology, clinical aspects, and prevention of STDs in homosexual youth. This discussion focuses on male adolescents, because STDs are uncommon among exclusively homosexual women.

Journal Article↗
PubMedDate not supplied

Prevalence of antibodies to herpes simplex virus 2 among homosexual men either positive or negative for human immunodeficiency viruses in Slovakia.

We determined the prevalence of antibodies to herpes simplex virus 2 (HSV-2, HSV-2 antibodies) in sera of homosexual men either positive for human immunodeficiency virus 1 (HIV-1, HIV+, a group of 27 sera) or negative for HIV-1 and HIV-2 (HIV-, a group of 52 sera) in Slovakia. Antibodies to HSV-2 glycoprotein G-2 (gG-2, gG-2 antibodies) were determined by a double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA) and immunoblot analysis. We found that 40% of HIV+ and 23% of HIV- homosexual men were positive for the gG-2 antibodies, what is 3.6 and 2.1 times higher incidence, respectively, than that in the control heterosexual population (Bystrická et al., Acta Virol. 42, 319-324, 1998). Identification of individuals infected with genital herpes among HIV+ and HIV- homosexual men should be succeeded by antiviral therapy in order to prevent transmission of HSV-2 and HIV as well in this community.

Antibodies, Viral↗
PubMed1987

Immune impairments and antibodies to HTLVIII/LAV in asymptomatic male homosexuals in Israel: relevance to the risk of acquired immune deficiency syndrome (AIDS).

We have studied 288 Israeli asymptomatic male homosexuals (MHS) to determine the prevalence of antibodies to HTLVI and HTLVIII and their correlation with impairments of the immune system and serum interferon (IFN). Seropositivity for HTLVI, HTLVIII, or both was found in 1.4, 8.3, and 0%, respectively. Significant decreases in the total peripheral T cells, TH cells, and TH/TS ratio as well as elevated alpha IFN serum levels were found in the MHS group in comparison with normal controls. Although no difference in the prevalence of either immune derangements or elevated serum IFN was observed between HTLVIII/LAV-seropositive and HTLVIII/LAV-seronegative MHS, the decreases in total T cells, TH cells, and TH/TS ratios were significantly greater in the seropositive MHS. These results indicate that (a) immune impairments and IFN system activation occur commonly in homosexuals, precede their exposure to HTLVIII/LAV, and probably reflect this group's increased risk for AIDS and (b) HTLVIII/LAV infection of MHS aggravates further their preexisting immune impairments.

Acquired Immunodeficiency Syndrome↗
PubMed1994

Contingent negative variation (CNV) and erotic preference in self-declared homosexuals and in child sex offenders.

Contingent negative variation (CNV) was recorded bilaterally from central electrodes using a "match/mismatch" paradigm in (Study 1) samples of heterosexual men (N = 6), gay men (N = 10) and lesbian women (N = 14) and (Study 2) in samples of child sex offenders (N = 34) and heterosexual control men (N = 19). Sexual orientation was assessed using the Multidimensional Scale of Sexuality (MSS) and the Human Sexuality Questionnaire (HSQ). Separate CNV averages were formed for each condition of stimulation: for Study 1, slides of adult male and female nudes; for Study 2, slides of child, pubescent and adult male and female nudes. Penile plethysmographic (PPG) data were also obtained from 15 of the child sex offender sample while they viewed stimuli of the same categories as were used in the CNV recording. On the basis of their PPG responses to children, child sex offenders were classified as either "pedophiles" or "non-pedophiles". In Study 1 significant Group x Sex (of slide) and Group x Electrode interactions indicated that: (i) heterosexual men (but neither homosexual group) showed significantly larger CNVs to female than to male slides; (ii) both homosexual groups showed significantly asymmetrical (R > L) CNVs. In Study 2, controls showed significantly greater CNVs to adult females than to both adult males and female children. Child sex offenders showed no significant differences in CNV to male and female slides for any age. "Non-pedophiles" showed significantly larger CNVs to female adults than to female children, but "pedophiles" did not. It is concluded that CNV has promise as a measure of both deviant and non-deviant sexual preference.

Adolescent↗
PubMed1998

A state space model for the HIV epidemic in homosexual populations and some applications.

In this paper we have developed a state space model for the HIV epidemic in homosexual populations which have been divided into subpopulations according to sexual activity levels. In this model, the stochastic dynamic system model is the stochastic model of the HIV epidemic in terms of the chain multinomial model whereas the observation model is a statistical model based on the observed AIDS incidences. This model is applied to the San Francisco homosexual population for estimating the numbers of susceptible people, infective people and AIDS cases and for estimating the probabilities of HIV transmission from infective people to susceptible people given sexual contacts. The results show that the estimated numbers of AIDS incidence trace closely the observed numbers indicating the usefulness of the model. It is observed that the estimated numbers of latent people show multimodal curves and that HIV infection takes place during the primary stage and very late stage. The results have further shown that there are significant differences between the observed AIDS incidences and the estimates by the embedded deterministic model. These results indicate that using the embedded deterministic model to estimate the HIV-infected people and to predict future AIDS cases can be very misleading in some cases.

Acquired Immunodeficiency Syndrome↗
PubMed1995

Sex differences in attitudes toward homosexuality: a comment on Oliver and Hyde (1993)

In a recent article, M. B. Oliver and J. S. Hyde (1993) reported the results of a set of meta-analyses of gender differences on a number of sexuality-related variables, including attitudes toward homosexuality. The small number of studies on this topic included in the review suggested that Oliver and Hyde's literature search strategy overlooked a number of studies. This article reports the results of a new meta-analysis using an expanded search strategy. In contrast to Oliver and Hyde's results, it was found that men held more negative attitudes toward homosexuality and, to a lesser extent, the civil rights of lesbians and gay men than did women. Effect sizes were moderated by subject population, with general adult samples showing no sex difference and other samples showing larger effect sizes. Effect sizes also varied as a function of the sex of the person rated, with larger sex differences for gay men than for lesbians. The implications of the results for the process of literature reviewing and for gender-based explanations of antigay prejudice are discussed.

Adult↗
PubMed1993

Why do homosexual men relapse into unsafe sex? Predictors of resumption of unprotected anogenital intercourse with casual partners.

OBJECTIVE: To assess predictors of relapse into unprotected anogenital intercourse with casual partners among homosexual men in Amsterdam, The Netherlands. DESIGN: A prospective study ongoing since October 1984. METHODS: Self-reported data on sexual behaviour were obtained at 12 semi-annual intervals. Participants who reported unprotected anogenital intercourse with casual partners at wave 12 but not at wave 11 were considered to have relapsed into unsafe sex (n = 47). Men who did not report unprotected anogenital intercourse at wave 11 or at wave 12 were considered to have maintained behaviour change (n = 197). RESULTS: Relapse into unsafe sex with casual partners occurred more frequently among men with a less positive attitude towards condom use, lower personal efficacy with respect to using condoms with casual partners, a weaker intention to avoid anogenital intercourse with casual partners and those who were not involved in a primary relationship. Intention to avoid anogenital intercourse with casual partners was related to an individual's attitude, normative beliefs and personal efficacy with respect to avoiding anogenital intercourse. CONCLUSIONS: In order to improve motivation it is important to support homosexual men in their personal decision-making process, which may be more resolute when the outcome is in accordance with individual preferences. Therefore, health education should be community-based and sensitive to individual needs.

Adult↗
PubMedDate not supplied

Sexually transmitted diseases and homosexuality.

An epidemic of sexually transmitted diseases, culminating in the emergence of acquired immune-deficiency states, has developed among homosexually active men during the past ten to 15 years. This epidemic is reviewed in relation to causative factors, priorities for control, and recommendations for control and prevention. Causative factors are divided into physical, behavioral, cultural, and political factors. Given the complicated interactions of these factors and the numerous diseases epidemic in the homosexuality active population, priorities need to be established for research and control programs that take into account the overall health impact of each disease and the effectiveness of available and potential resources. Finally, educational programs must be developed that will overcome the limited effectiveness of public health control efforts in this area, or we may expect even more serious and widespread health care problems.

Acquired Immunodeficiency Syndrome↗
PubMed1999

Family adjustment following disclosure of homosexuality by a member: themes discerned in narrative accounts.

Disclosure of homosexuality by a family member frequently creates a crisis within the family. Previous research has focused primarily on families' response to this initial crisis and how they cope with and transform initial negative reactions. Little attention has been given to how families respond to disclosure over time and to how families integrate a gay or lesbian family member--and his or her relationships--once they have come to accept his or her homosexuality. Using a narrative approach and interviewing whole families, this project explores these questions. We present 12 themes we found consistently recurring in family members' narratives. We discuss the relationship between these themes and current models in the literature within the context of heterosexism and suggest that this approach may represent a first step in developing a model of successful adaptation subsequent to disclosure.

Adult↗
PubMed1990

Anti-sperm antibodies in homosexual men: prevalence and correlation with sexual behaviour.

The sera of 60 homosexual males were examined for the presence of antibodies to sperm using an indirect immunobead test (IBT). Six of 60 (10%) had antibodies of IgG isotype; in addition two of the six had antibodies of IgA isotype. The presence of antibodies was associated with the practice of unprotected receptive anal intercourse in the previous six months. Antibodies were not found in homosexual men who were celibate, or who practised only oral intercourse during the same period. There was no correlation between the presence of anti-sperm antibodies and antibodies to human immunodeficiency virus (HIV), or numbers of T lymphocytes. These preliminary results lend support to the hypothesis that antigen presentation in the lower gut may be a source of sensitisation against sperm. The possibility that anti-sperm antibodies may be a marker of receptive anal intercourse merits further investigation.

Adult↗
PubMed1995

The decision to remove homosexuality from the DSM: twenty years later.

Twenty years have passed since the American Psychiatric Association (APA) voted, in 1973, to remove "Ego-syntonic Homosexuality" from the Diagnostic and Statistical Manual of Mental Disorders (DSM). The present study investigates the influence of the patient's sexual orientation on the therapist's perception of the former's mental health. Four hundred and seventeen Israeli therapists (psychiatrists, clinical psychologists, and social workers) participated in the study, representing a cross-section of professionals in the mental health services in Israel. The measures included a demographic questionnaire and a perceived-severity scale of rating. Participants were assigned case histories where a hypothetical patient was heterosexual or ego-syntonic homosexual. Attributions of severity of mental status were found to differ as a function of sexual orientation of patient. Results are discussed in terms of the latent function of psychotherapy, considering the contrast between the liberal political attitudes and the secular way of life of the therapists on the one hand and their conservatism in the clinical domain on the other hand.

Adult↗
PubMed1993

Homosexuals and AIDS: a new approach to the illness.

AIDS, historically connected with homosexuals, has provoked a number of social, psychological, and moral reactions within the homosexual community itself as well as elsewhere. Among questions raised, there are all those concerning the meaning and place of human sexuality. Between strict moral condemnation and publicity for "Safer Sex," there is room for a personal ethic, reflection, and a more responsible behavior.

Acquired Immunodeficiency Syndrome↗
PubMed1997

AIDS and the new medical gaze: bio-politics, AIDS, and homosexuality.

The essay argues that the contemporary resurgence of homophobia and the remedicalization of homosexuals in the wake of AIDS is, in part, an unintended but predictable effect of a quarter century of fractious identity-politics. Prominent gay and lesbian political strategies of the 1970s and 1980s borrowed heavily from increasingly discredited, if once politically correct, discourses that valorized individuals on the basis of membership in governmentally constructed bio-bureaucratic categories. Drawing on the work of prominent gay intellectuals, such as Foucault, Watney, and Richard Rodriguez, and locating their insights within the context of contemporary cultural and political conflicts, the essay argues that gay advocates who essentialize homosexual identity, however benignly, unwittingly participate in constituting the ground for an emergence of a neoeugenic movement at millennium's end. The essay concludes with the observation that escaping the conceptual prison of bio-bureaucratic categories is not a uniquely gay or lesbian task. It is a human task.

Acquired Immunodeficiency Syndrome↗
PubMed2002

Crooked men and straightened women: images of homosexuality across race in two women's magazines, 1986-1995.

Images of traditional sexuality, across race, prevail in mass media, especially in women's magazines. While omitting less traditional sexual practices for the most part, New Woman and Essence magazines construct the image of a bisexual male who threatens the heterosexual woman and the legitimate heterosexual couple. These women's magazines also redefine homosexual activity, suggesting women who experience homosexual inclinations are really engaging in normal heterosexual behavior.

Attitude↗
PubMed2002

The effects of social contact with a lesbian person on the attitude change toward homosexuality in Turkey.

The study examined whether we could observe an attitude change in heterosexual participants introduced to a lesbian person. Eighty-nine undergraduate students from Middle East Technical University (METU) received a Turkish version of Hudson and Ricketts' scale about "Attitudes toward Homosexuals" during a pre-testing session. Fifty-four students who didn't have any social contact with homosexuals were chosen for the present study. Forty-five days after the pre-testing, heterosexual participants were randomly assigned either to experimental (social contact with a lesbian person) or to control (no contact with a lesbian) conditions. Participants in the experimental condition were introduced to a lesbian in a classroom situation. The lesbian person gave information about herself and answered the questions of heterosexual students. After that, participants in both experimental and control conditions received Hudson and Ricketts' scale again. Results demonstrated that there was a significant difference between the means of pre-test and of post-test in the experimental condition.

Adult↗