Preventing bacterial endocarditis. Correction.
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After reporting a clinical case of a patient with a Staphylococcus Aureus Acute Endocarditis involving the aortic valve being complicated with cardiac failure irresponsive to medical treatment, which required a surgical procedure, the authors describe the preoperative echocardiography features. These features have the particularity of identifying a pseudoaneurysm rising in the outflow tract of the left ventricle, that involves the annulus and the anterior mitral leaflet, opening into the left atrium. They also take the opportunity to review the main local complications of Infective Endocarditis, affecting native or prosthetic valves, and make some comments on the diagnostic echocardiographic possibilities.
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A twenty-three years old woman, without previous heart disease developed endocarditis with negative bloods cultures on the fourth month of her third pregnancy. Fever was controlled through antibiotics, however she developed cardiac insufficiency and was submitted to surgery for replacement of aortic valve with a bioprosthesis. The post operative period showed no problems and the patient was discharged on the forty second day after admission. On the thirty ninth week of pregnancy she gave cesarean birth, without complications. The newly born, apgar 5 (1 min.) and 7 (5 min) presented signs of neurological problems, characterized on the second month as a cerebral atrophy. Among various possible factors, the most likely would be cardiopulmonary bypass circulation as the cause of the neurological malformation.
Central venous cannulation is a commonly used technique in the management of seriously ill patients. In experienced hands, the complication rate is low and primarily includes sepsis, thrombosis and local trauma. For chronic indwelling central venous catheters, thrombus formation within the right atrium has been described, particularly in premature infants, and a recent case has been reported in an adult. Valvular damage in the right heart is recognised and more often diagnosed at autopsy. This report describes the presence of tricuspid vegetations in a diabetic woman, related to the insertion of a central venous cannula.
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Dental procedures may be associated to transient bacteraemias that, in the past, were believed to be the most common cause of infective endocarditis, mainly in patients with rheumatic or congenital heart disease. However, a careful survey of the recent published reports indicate that the real risk to develop endocarditis following dental procedures is actually low, because the bacteraemias are very short in duration and several statistics demonstrate that only a few patients with endocarditis had undergone any dental procedure before the onset of the illness. In patients at risk, however, when some major dental interventions are needed, oral chemoprophylaxis with amoxicillin orally administered, appears prudent; parenteral administration of antibiotics (amoxicillin associated to gentamicin or other drugs) is indicated in high risk patients only.
The two techniques usually employed for the surgical treatment of tricuspid valve endocarditis are valve replacement or simple valve excision without valve replacement. A third more conservative procedure consists of resection of the vegetation ("vegetectomy") and leaflet repair, if necessary. Valve excision without valve replacement is described in adult patients especially in addicts of intravenous drugs, with normal ventricular function. Two cases of tricuspid valve endocarditis in children with interventricular communication successfully treated by "vegetectomy" and valve excision without valve replacement are reported. In the first case, surgery was performed during acute infection. Contrarily in the other case there was evidence that cure had been obtained, but still the prosthesis was not implanted due to the excellent hemodynamic status at the moment, and to abbreviate bypass time due to the preoperative conditions of the child. The uncommon approach to these two cases of tricuspid valve endocarditis in childhood motivated this presentation.
This article indicates that using local degerming agents in conjunction with traditional antibiotics prevents dental bacteremia more effectively than either procedure alone. In many patients at risk for endocarditis who practice home-care procedures than can produce bacteremia from gingival bleeding, daily antibiotic prophylaxis is impractical and contraindicated. This article discusses an effective method to control daily bacteremia with 0.2% chlorhexidine mouthwash. The article also attempts to identify patients at risk, determine the degree that they are exposed to potentially bacteremic situations, and encourage an aggressive team approach of physician and dentist to protect such patients adequately. Recommendations to prevent bacteremia are offered to supplement traditional antibiotic regimens.
Twenty-one patients with infectious endocarditis are reported. The diagnosis was based on finding of at least three clinical symptoms and signs, including systemic manifestations, cardiovascular signs such as the appearance of a new or changing symptoms of cardiac failure, episodes of embolism and abnormalities in laboratory investigations and features of valvular involvement by the inflammatory process, principal changing endocardium image was evidence of an active inflammatory process. The aetiological factors, diagnostic difficulties, therapeutic results and the usefulness of echocardiography in the diagnosis of infectious endocarditis are discussed.
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The authors report a case of infectious spondylodiscitis revealing a staphylococcal endocarditis in a patient with a Carpentier aortic heterograft. This case, along with 60 descriptions from the literature, has enabled them to specify the characteristics of occurrence of endocarditis during a spondylodiscitis. The clinical factors in favor of this association are: a pre-existing cardiopathy, an oral port of entry, occurrence of other rheumatoid manifestations, even more the presence of complications of endocarditis. The laboratory factors in favor of an association are: discovery of an inflammatory anemia, of circulating immune complexes, of a cryoglobulinemia, of a rheumatoid factor, of hematuria. But it is mostly the demonstration of streptococcus in blood cultures and other samples that should be an indication to search for an endocarditis, the course of which dominates the prognosis.