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Inflammatory sarcomatoid carcinoma: a case report and discussion of a malignant tumor with benign appearance.

Inflammatory sarcomatoid carcinoma is an aggressive tumor with an unusually benign appearance. We report the case of a 65-year-old man with a history of inoperable poorly differentiated carcinoma of the right lung, for which he had received chemoradiotherapy. A new solitary mass was discovered 4 years later in the left lung on surveillance computed tomography. The patient underwent thoracotomy with a wedge biopsy on which frozen section was performed. The nodule was vaguely granulomatous and associated with a mixed inflammatory infiltrate and a deceptively bland spindle cell proliferation. Results of immunoperoxidase studies, however, showed that the nodule contained neoplastic cells with an epithelial phenotype that were invading the pulmonary vessels. These are features of the rare inflammatory sarcomatoid carcinoma. In contrast to sarcomatoid carcinomas, this case highlights the deceptively benign appearance of inflammatory sarcomatoid carcinoma. This leads us to concur with the recommendation to exercise caution when attempting the diagnosis of apparently benign lesions on intraoperative frozen section in patients with high clinical suspicion of malignancy.

Aged↗

The proofing challenge: finding hidden errors.

Page proofs are deceptive. The beautiful fonts, printout and lay-out of page proofs can be deceptive, because there are usually some errors still lurking. Most nursing journals send page proofs to authors, but most authors are not experienced at proofing final pages for publication, so errors can sneak through. This article provides tips on proofing final pages so that those pesky, final errors can be corrected before printing.

Humans↗

Psychological response styles and cardiovascular health: confound or independent risk factor?

Using results from 2 large cardiovascular studies, the authors examined the utility of treating psychological response styles as confounds (e.g., factors undermining relationships with other self-report variables) versus distinct personality traits in the prediction of cardiovascular health. Study 1 consisted of a 3-year prospective study of ambulatory blood pressure levels in healthy adults (N = 125). Study 2 comprised a 12-week drug treatment program for ischemic heart disease patients (N = 95). Participants completed measures of psychological factors and self-deception and impression management in each study. Results consistently favored using response styles as direct predictors. Self-deception scores predicted elevated 3-year diastolic and systolic blood pressure changes in Study 1 and poorer treatment outcomes in Study 2. Statistically controlling for response style effects within the psychological factors generally did not improve predictions. These findings argue against the conceptualization of response styles as stylistic confounds.

Adult↗

Factors influencing self-administration of, and subjective response to, placebo marijuana.

Self-administration of, and subjective response to, placebo marijuana were studied in two groups of regular marijuana smokers. One group received the drug under a set of instructions that informed them that the marijuana was active (deceptive administration); the other group was informed that the marijuana might be inactive (double-blind administration). Subjects were allowed to smoke placebo marijuana freely for 60min during four identical weekly sessions. Subjects smoked an average of 6.0 half-length cigarettes per session, resulting in a mean increase in expired air carbon monoxide of 14.6 ppm. Placebo self-administration did not change significantly across the four sessions. Smoking was associated with marijuana-like subjective effects. Subjects in the deceptive administration group smoked more placebo marijuana and reported a greater subjective response than the other group during the first session only. Several anamnestic factors (drug use history, current pattern of marijuana use, dimensions of personality) correlated with the amount of placebo self-administered, and subjects with less marijuana experience tended to report stronger subjective responses to the placebo. These results demonstrate the importance of including a placebo control when studying the reinforcing effects of marijuana and identify some factors that might predict placebo responses to marijuana or other drugs.

Journal Article↗

[Hallucinations and experience of fear].

Hallucinations, which are experienced in fear-evoking situations of helplessness and (external) danger, are attempts of defence and the realisation of elementary needs of self-preservation and security. The reality-denying self-deception is accompanied by the mobilisation of own protective potencies. Hallucinations are experienced fearfully, so that there is a situation of helplessness and danger. They are--as neurotic symptoms--an attempt to realise libidinous and/or aggressive desires with the manifestation of (condemning and punishing) defence in the projective perception. The self-deception here concerns the denial of own internal conflicts.

Defense Mechanisms↗

Patel v. Immigration Appeal Tribunal, 5 May 1988.

The respondent was a stateless person who had originally entered the UK by falsely stating that he was unmarried. After he left the UK to visit India, the Government refused to let him re-enter on the ground that his false statement was made to avoid immigration laws and thus rendered his exclusion "conducive to the public good." He challenged this action, arguing that, under Section 3(5)(b) of the Immigration Act 1971, his exclusion could be deemed "conducive to the public good" for reasons of dishonest deception only if the deception had occurred after leave to enter had been obtained. The Court rejected this argument and held that no distinction should be made with respect to false statements made in order to enter the UK and false statements made later in order to stay there.

Demography↗

Mother and Unborn Baby Care v. State, 11 May 1988.

The State charged the defendant antiabortion organization with violation of the Texas Deceptive Trade Practices Act in advertising under abortion groups in the yellow pages. The Court upheld a lower court decision enjoining deceptive conduct, mandating certain disclosures, and assessing penalties. It rejected the defendant's argument that it was not involved in trade or commerce and, thus, was not subject to the Act. As support for its decision, the Court pointed to the defendant's advertising in the yellow pages and provision of pregnancy testing, counseling, financial assistance, aid in adoption procedures, and help in obtaining legal aid.

Abortion, Induced↗

Patterns of socially desirable responding among perpetrators and victims of wife assault.

Wife assaulters attending a treatment group and women who had just exited an abusive relationship were asked to report on the extent of physical violence and emotional abuse in their relationship. Measures of socially desirable responding (SDR) were administered to both groups. Wife assaulters' self-reports of physical abuse correlated negatively with one SDR measure (the Balanced Inventory of Desirable Responding) but not another (the Marlowe-Crowne Social Desirability Scale); emotional abuse correlated negatively with both measures. Although physical abuse was primarily related to impression management, psychological abuse was affected by both impression management and self-deception aspects of SDR. Wife assaulters' reports of their own anger also correlated negatively with SDR. Both self-deception and impression management appear to contribute to underreporting of anger. Finally, abuse victims' reports of both physical and emotional abuse were unrelated to SDR.

Adult↗

Diffusion-weighted imaging in the setting of diffuse cortical laminar necrosis and hypoxic-ischemic encephalopathy.

BACKGROUND AND PURPOSE: As is the case for CT scans, MR images may occasionally appear deceptively normal unless proper windowing is used. We sought to illustrate the necessity for proper windowing and for assessing the gray-white matter differentiation on diffusion-weighted (DW) images in the setting of hypoxic-ischemic encephalopathy. METHODS: Six comatose patients (age range, 34-56 years) underwent MR imaging in the early phase (range, 1-5 days) after severe anoxic insult. T2-weighted, turbo fluid-attenuated inversion-recovery, and DW images were obtained in all six patients, with contrast-enhanced T1-weighted images obtained in four and apparent diffusion coefficient (ADC) maps in five of the six patients. RESULTS: At presentation, each of the six patients had symmetric, uniform hyperintensity in the cortex (mean ADC, 0.35 x 10(-3) mm(2)/s) relative to the white matter (mean ADC, 0.91 x 10(-3) mm(2)/s) on DW images. Each also had a poor outcome: brain death in four patients and a permanent vegetative state in two patients. CONCLUSION: The appearance of the MR images in the setting of diffuse cortical laminar necrosis can be deceptive to the unwary radiologist. The key to correct interpretation is proper windowing and the marked gray-white matter differentiation on spin-echo images but best seen on properly windowed DW images in the early subacute phase. This appearance also implies an extremely poor outcome, either a permanent vegetative state or brain death.

Adult↗

[Perception of a group of women about having HPV].

BACKGROUND: The possibility to acquire sexually transmitted diseases generates bio-psycho-social conflicts affecting daily life of women. OBJECTIVE: To investigate the knowledge of women on the concept of being infected by the human papilloma virus (HPV) and to understand the significance they attributed to their condition as HPV carriers. MATERIAL AND METHOD: It is a qualitative study in which ten women were interviewed, after the result of a cytopathological exam suggesting HPV. Data were collected at the Center of Health School of the Universidade Estadual Paulista-UNESP-Brazil. RESULTS: The significant items were: deception and preoccupation about the cure, since they indicate that it is very deceptive to be infected with an incurable disease by a person whom they trust; the method of having sexual relations and being infected again; the necessity of care and of being optimistic to face the disease and the threat of cervix cancer originating anxiety. DISCUSSION: Orientations made by health professionals were efficacious to clarify the relationship with cancer development. It is possible to understand the necessity of assistance orientations and the opportunity to hear them, offering individualized quality care. This study also offers important elements to reinforce the educational role of health professionals, principally those referring to sexually transmitted infection and cancer, seeking prevention and early treatment with the offered information. However, there is no desire of finishing the subject regarding perception, thus there is much to discover about diseases related to human papilloma virus.

Adolescent↗

Use of non-verbal construing and metaphor in psychotherapy.

This article begins by looking at the way we try to construe or make sense of the world in which we live. How in the very nature of such sense-making there is the potential for sowing the seeds of self-deception by trying to fit our (relatively simplified) bipolar constructs to a complex unitary universe. Non-verbal and verbal construing are compared. Verbal construing enables us to reach an even more sophisticated level of self-deception, via myths created by limiting metaphors--such as "man-the-machine." The institutions which we create and the people who are invested in them tend to solidify in-group myths, often with the help of metaphor. It is argued that personal, constructivist, and eclectic approaches to psychotherapy can be envisaged as enterprises to begin the process of demythologising clients in the safety of the therapeutic setting. In therapy, clients can experiment with empowering themselves in reconstruing the problem areas of their lives and actively testing out these new constructions against personal experience. Clients can also learn to explore the meaning behind symptoms, i.e., to give cognitive form to feeling with the help of their intuitive sensitivity.

Concept Formation↗

The efficacy of nicotine gum in group-centered smoking cessation therapy in a family practice.

The efficacy of nicotine gum in conjunction with group support for smoking cessation was examined. Of 388 participants enrolled in the smoking cessation program, lapse-free abstinence rates of 38 percent and 30 percent were obtained at six and 12 months follow-up, respectively. One-year abstinence rates were confirmed by the measurement of expired carbon monoxide levels. One third of claimed abstainers were randomly selected at one-year follow-up for confirmation, with a resultant 3 percent deception rate. When this deception rate was applied to the overall results, six-month and 12-month abstinence rates became 36 percent and 29 percent, respectively. These abstinence rates suggest an efficacious role for nicotine gum in association with group support.

Adolescent↗

Voice stress evaluators and lie detection.

Proponents of vocal stress analysis systems argue that they are able to detect spoken deception by analysis of "stress" in the voice signal. Presumably, they do so by examining traces made by laryngeal microtremors which, they claim exist in the voice, are associated with stress, and ultimately are associated with lying. However, most research that seeks to identify the relationships between microtremors and laryngeal function has produced negative results, and data on the ability of voice analyzers to detect stress from speech--or to identify spoken deception--have been negative or "mixed" in nature. Since perspectives based on available results leave a number of questions unanswered, a series of experiments has been undertaken. The first was focused on the basic acoustic/temporal correlates of stress in voice (the subject of an earlier report), the second on examination of stress by commercial voice analyzers, and the third on the detection of relatively high-risk lies by this same type of voice analysis procedure. It was found that correct stress/nonstress identifications occurred only at chance levels; the lie/nonlie identification scores were quite similar with professional "examiners" performing at about the same level of accuracy as other auditors. The following review is divided into two parts: a history of the controversy and a presentation of the two cited experiments.

Adult↗

Cryptic otalgia: a case of Munchausen syndrome in a pediatric patient.

This paper reports a case of Munchausen syndrome in a pediatric patient. The patient, a 13-year-old boy, presented with a complaint of persistent otalgia. As a result of the patient's deception of his physicians, he underwent numerous unnecessary investigations and two unnecessary operative procedures. The patient's deception included the simulation of a cerebrospinal fluid leak. The literature with respect to Munchausen syndrome in the pediatric patient is reviewed. Emphasis is placed on the fact that physicians, by their investigations and treatments, inflict most of the morbidity on this group of patients. Specific warning signals as well as an approach for management of these patients are also reviewed.

Adolescent↗

The therapeutics of placebo.

The use of placebo is not old-fashioned, ineffective or unethical. It requires an ongoing, trusting relationship between the physician and the patient. Deception of the patient and self-deception must be avoided. Under these conditions, there are specific situations in which placebo is the treatment of choice.

Adult↗

Malignant lesions of the female genital tract and peritoneum that may be underdiagnosed.

Female genital tract neoplasms that may have a deceptively benign appearance and selected frankly malignant neoplasms that may be misinterpreted as less aggressive lesions are reviewed. In the uterine cervix, the two major neoplasms in this group are the minimal deviation adenocarcinomas of mucinous and endometrioid types. The latter subtype has only recently been described. Endometrioid adenocarcinomas, usually of the uterine corpus, but occasionally of other sites, may have microglandular patterns that can lead to their misdiagnosis, sometimes as microglandular hyperplasia. Pure squamous cell carcinomas of the uterine corpus frequently are composed of very well differentiated epithelium, so that it is possible to misinterpret them as nonneoplastic, and a similar phenomenon may occur in association with the squamous element in some adenocarcinomas with squamous differentiation. Other uterine entities that may be underdiagnosed are malignant lymphoma of the cervix, placental site trophoblastic tumor, myxoid leiomyosarcoma, endometrial stromal sarcoma with glandular differentiation, and mullerian adenosarcoma. Consideration of a variety of architectural and cytological features should facilitate their interpretation. One recently described variant of adenocarcinoma of the fallopian tube that may be confused with the usually clinically benign female adnexal tumors of probable Wolffian origin is microfollicular endometrioid adenocarcinoma. Ovarian tumors subject to misinterpretation that are reviewed herein include metastatic tumors with deceptively benign foci, endometrioid adenocarcinomas that may be misdiagnosed as sex cord tumors, and cystic granulosa cell tumors that may be misinterpreted as follicle cysts. Finally, rare variants of malignant mesothelioma that may be underdiagnosed are reviewed.

Adenocarcinoma↗

[The unmasking of consciousness by means of criticism of illusion and ideology].

The author contends that the constitution of Psychology as a Science requires the elucidation of the conceptual instruments to be used in the approach of its specific theoretical object. In order to meet that requirement, three main methodological subjects are considered: I. The image, conceived as embodiment of the illusory and the deceptive, vs. the image as "the imaginary". Images are defined as representations determined a priori as the sole possibility of understanding reality. The distinction is made between two modes of this gnoseological process: the one, apparent, the other real. The first one, image as a representation having no correspondence whatsoever with reality, conveys only deceptive features: illusion at the individual level, and ideology at the broader scale of the socioeconomical class. Illusion and ideology are subject to parallel in that both mask reality, uncovering a part of it in order to hide the whole; and they imply each other in that to each illusion of individual consciousness corresponds a single socio-economical ideology. The unmasking must be performed both at the individual (illusion) and the collective (ideology) levels, through a conceptual work under a clear conception of knowledge and its methods, leading to an actually objectivating neutral act-Husserl. II. The imaginary as a project of irreality. Accepting that the image has a double function: a) an essential (gnoseological) one, and b) an unesential, supplementary one, as the support of illusion and ideology, there is yet a double manner for the concealment: a) subjective or belonging to the psychological level, and b) objective-intersubjective level, or actual social level. The image provides the object for the "belief", being thus the basis for the creation of a super-reality, an invention over another invention, with the goal of fulfilling desire. This goal implies failure in itself, as desire is always beyond the reality that seeks its fulfillment. The process of illusion can be explained by the triple link: desire-imagination-illusion, leading to belief. In desire there is a double work: a) a positive one, or trend towards the appropriation of the object; and b) a negative one, or the all-present frustration leading, precisely, to illusion. III. Desire and discourse: dialectics of possibility. Reality provides a limit-border to desire: it sets the frontiers of impossibility. Only the discourse provides a program, a planification of the being-desire. But desire exceeds the limits of possibility, and sets the underlying framework on which the impossibility of desire is expressed. Two different answers have been attempted from a logical-gnoseological-methodological stand point, consisting of reductionisms or pseudo-answers. Firstly, intellectualism, professing to reduce everything to rational cathegories and their logico-formal methods; and secondly, naturalism, professing to reduce everything to a factic-empirical scheme and to its experimental method...

Consciousness↗

Patterns of disclosure and perceptions of the human immunodeficiency virus in infected elementary school-age children.

OBJECTIVE: To investigate the patterns of disclosure and perceptions of human immunodeficiency virus (HIV) status in a group of HIV-infected elementary school-age children. DESIGN: A survey. SETTING: A referred care university hospital center. PATIENTS: All HIV-infected children born before August 31, 1985, and scheduled for ambulatory follow-up between 1984 and 1993 were eligible for the study. A total of 35 HIV-infected (21 asymptomatic and 14 symptomatic) elementary school-age children (aged 5-10 years) were examined between 1990 and 1993. MAIN OUTCOME MEASURES: Semistructured qualitative interviews were used, 1 with the children and 1 with their parents or caregivers. In addition, 3 drawings per child were also analyzed. RESULTS: Partial disclosure was observed in 14 (40%) of the children, and full disclosure of the diagnosis of acquired immunodeficiency syndrome was given to 6 (17%) of the children. Secrecy regarding serostatus was the strategy used by 15 (43%) of the parents or caregivers involving either complete nondisclosure (n = 8) or deception by means of attributing the symptoms to another condition, medical or other (n = 7). Perceived health status and clinical status differed for 11 (31%) of the children. Eight children did not identify any illness causality, and most of the others gave prelogical or concrete-logical explanations. Few children were aware of their parent's infection or disease. CONCLUSION: Human immunodeficiency virus-infected elementary school-age children were exposed to various disclosure patterns regarding their HIV infection or disease, and most children (26/35 [74%]) reported stressful experiences due to HIV regardless of the disclosure patterns.

Art↗