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[Tularemia, a potential bioterrorism weapon].

A POTENTIAL WEAPON: Because of its highly contagious nature with a low inoculum, principally with the biovar A, F. tularensis is considered as an agent that could be used by terrorists, notably when sprayed. Any epidemic of tularemia, essentially in its respiratory form, particularly in areas of low incidence of this infection, should be suspected to be a biowarfare attack. The voluntary contamination of water with this bacteria could also be used as a biological weapon. THE DIFFERENT FORMS OF THE DISEASE: Depend on the mode of contamination, the dose of inoculum and the virulence of the strains. The forms are pulmonary, ulcerous-glandular, typhoid, glandular, ocular-glandular, oropharyngeal and septicemic. IN GENERAL PRACTICE: Tularemia is a disease that requires official notification. Many guidelines exist for the treatment and prophylaxis of patients having been exposed to F. tularensis.

Adult↗

When bioterrorism strikes: diagnosis and management of inhalational anthrax.

In October and November, 2001, reports of patients with inhalational anthrax reacquainted the public with this ancient disease and introduced the harsh reality of a bioterrorist act. Bacillus anthracis, a rod-shaped, spore-forming bacterium, primarily infects herbivores. Humans traditionally have acquired the disease from occupational or agricultural exposure to infected animals and animal products. Recent events saw the intentional release of anthrax spores, using the U.S. postal system as an unlikely and unwilling agent. Cutaneous disease, pulmonary disease, and gastrointestinal anthrax are the known clinical manifestations of anthrax. Inhalational anthrax has the highest mortality and is the main focus of this report.

Anthrax↗