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PubMed2001

[Conduction aphasia and phonemic disorder].

Conduction aphasia is usually described as a repetition impairment. Semiology or pathophysiology cannot be explained with this definition. We report a single case particularly demonstrative. The patient showed spontaneous speech, denomination, repetition and reading impairments. Main errors were phonemic paraphasia. No arthric disorder nor comprehension impairment was observed. Damage of supramarginalis gyrus and Wernicke's area was found. A cognitive analysis suggested that the phonological buffer and the working memory were impaired. Implication for rehabilitation, which included segmentation and semantisation associated to phonological training, is discussed. The course of the conduction aphasia was good and the patient was able to work again.

Aphasia, Conduction↗
PubMedDate not supplied

Distinct neurolinguistic symptom clusters in Alzheimer's-type dementia and primary progressive aphasia.

Mesulam's (1982) report describing six patients with a slowly progressive aphasia without accompanying signs of dementia led to the recognition of a syndrome now known as Primary Progressive Aphasia (PPA). Many more patients have been described since Mesulam's description was published (see Westbury & Bub, 1997, for a review). However, the published literature is both unsystematic and incomplete, making it difficult to place the findings into a coherent theoretical framework. In addition, little previous work (see Mesulam, 1987) has specifically attempted to specify the difference between PPA and dementia of Alzheimer's type (DAT), although the two disorders are easily confused since many language deficits can masquerade on early presentation as memory or cognitive deficits. In this paper, the linguistic deficits of 11 PPA patients are analyzed, and contrasted with the linguistic deficits of a group of 11 DAT patients. Patients in both groups were tested using an extensive battery of language tests, the Psycholinguistic Assessment of Language Battery (Caplan & Bub, 1990; Caplan, 1992). We consider seven linguistic symptom clusters that differentiate the two groups.

Aged↗
PubMed1975

[Aphasia syndromes in brain tumors. Clinico-pathological correlations].

A clinica-psychological and pathoanatomical analysis of 40 observations with neoplasms of the brain in the left dominant hemisphere and 4 observations with neoplasms in the right subdominant hemisphere, has been carried out. In 36 cases, a desintegration in the language in a form of aphasia, has been established, while in 4 cases this was not present. In 22 observations the established neuro-psychological syndrome completely indicated and coincided with the localization of the neoplasm in the corresponding part or parts of the brain, in 10 it only partialy coincided, while in 4 cases it did not coincide with the localization of the neoplasm in the brain. The established neuro-psychological syndrome in observations with neoplasms in the right subdominant hemisphere possesses only a tentative topico-diagnostical significance. In conclusion the authors consider that the established syndromes of aphasia in patients with neoplasms of the brain may be of a considerable significance and help in substantiating a precise topical diagnosis.

Adolescent↗
PubMed2002

[A case of Gogi aphasia with predominantly left temporal and parietal lobe atrophy].

We report a 68-year-old right-handed Japanese woman who had a history of progressive difficulty in understanding speech and naming. Neuropsychological examination presented Gogi (word meaning) aphasia and impairment of semantic memory for some common objects. She also presented acalculia and mild constructional impairment. There was no evidence of impairment in elementary perception and motor skills. Her memory performance of visual task was within normal range. She had neither personality change nor behavioral disorder. Magnetic resonance (MR) imaging showed atrophy in the left temporal lobe and the left parietal lobe. Single photon emission computed tomography (SPECT) scans demonstrated a decrease of regional cerebral blood flow in the atrophic sites and the left frontal lobe. We pointed out that the atrophy of the parietal lobe was atypical in the early stage of cortical degenerative disease presenting Gogi aphasia, in addition to in the light of classification of Fronto-Temporal Lobar Degeneration (FTLD).

Aged↗
PubMed1975

[Acoustic and semantic disturbances of comprehension in aphasia].

The authors carried out a verbal auditory comprehension test on 115 aphasic patients, 44 patients suffering from a left hemispheric lesion without aphasia and 120 normal subjects used as acontrol group. The test also revealed either disorders in acoustico-phonemic discrimination or difficulities in semantic differentiation. The main aim of the research was to check experimentally the theory propounded by Alajouanine and colleagues (1964) according to which, in Wernicke's aphasia, it is possible to demonstrate a twofold correlation between disorders of comprehension and speech disorders both phonemic and semantic. Only one part of the theory of Alajouanine and colleagues has been confirmed by our experiments for our results have shown that there is a very close correlation between semantic paraphasias and disorders of semantic differentiation whilst no correlation can be found between phonemic paraphasias and disturbances in auditory phonemic discrimination.

Aphasia↗
PubMed1975

[Today's treatment of aphasia--a travel report (author's transl)].

A visit was made to representative centres for the treatment of aphasia in five European countries and information gathered on their organisational structure. Instructional material and rehabilitation techniques were compared and a number of therapeutic methods identified. In this context it was noted that, due to a number of interesting approaches, the therapy of aphasia seems to be extensible and in many ways open to modifications.

Aphasia↗
PubMed2002

[A case of motor neuron disease with progressive aphasia and dementia].

We report a 71-year-old woman showing rapidly progressive non-fluent aphasia and dementia accompanied by motor neuron disease (MND). There was no family history of dementia or motor neuron disease. There was 10 months history of dysarthria and dysphagia. On examination, she showed profound difficulty in articulation. Her comprehension was impaired in that she was unable to obey three-stage command. Her written language was also impaired with phonological spelling errors, syntactic errors, and perseveration. Neuroradiological investigations showed atrophic changes and hypoperfusion of left temporal and bilateral parietal region revealed by MRI and SPECT, respectively. Her subsequent decline was rapid. It might be likely that aphasia is much more common in dementia with bulbar MND than is currently recognized because bulbar palsy might mask the language disorder.

Aged↗
PubMed2002

[Amyotrophic lateral sclerosis presented with alexia of kanji and word meaning aphasia].

We report a 63-year-old right-handed Japanese man with progressive bulbar dysfunction and alexia of kanji (Japanese morphograms). He was well until his 62 years of age, when he noted difficulty of reading kanji, which was followed by disturbances in his speech. Reading of kana (Japanese phonograms) was preserved. He also showed naming difficulties with semantic memory loss for words, which were characterized for word meaning aphasia or semantic dementia. He showed dysarthria and mild dysphagia with atrophy and fasciculations of the tongue. The electromyographic studies disclosed diffuse neurogenic pattern. He was diagnosed as having bulbar type amyotrophic lateral sclerosis. Cranial magnetic resonance imaging and single-photon emission computed tomography revealed bilateral involvements of the temporal lobes. Our patient appeared to meet the clinical criteria for frontotemporal degeneration of motor neuron disease type, and is the first case of amyotrophic lateral sclerosis showing alexia of kanji and word meaning aphasia.

Amyotrophic Lateral Sclerosis↗
PubMed1976

Reversal of aphasia with superficial temporal artery to middle cerebral artery anastomosis.

Two patients with aphasia which markedly regressed following superficial temporal to middle cerebral artery anastomoses are reported. Added to the armamentarium of stroke therapy for the amelioration of focal ischemic disease, modern microvascular techniques allow the establishment of collaterals to recipient vessels of less than 1 mm in diameter. A neurological deficit which is supposed to be permanent is usually considered a contraindication to these procedures. This report details two cases in which aphasia and motor weakness markedly improved following a superficial temporal artery to middle cerebral artery anastomosis.

Aged↗
PubMed1992

[Verbal ability of Alzheimer's disease patients and very elderly control patients using the Aachen aphasia test].

We assessed language function, using the Aachen aphasia test (AAT), in 14 subjects with Alzheimer's disease and 6 control patients. Aphasia did not occur in control patients, but in 11 of 14 Alzheimer's disease patients. Impairment of object naming was the most prevalent abnormality. Performance in AAT subtests repetition, written language, object naming, comprehension and token test correlated strongly with Mini-Mental State scores.

Aged↗
PubMed1992

[Acquired epileptic aphasia--Landau-Kleffner syndrome].

Authors report about a girl with Landau-Kleffner syndrome. After the history of normal developmental milestones at the age of five-and-half year the patient had absence seizures, and marked receptiv and expressiv aphasia developed gradually. She was found to have Landau-Kleffner syndrome. This entity initially can be regarded as deafness or psychiatric reaction. The seizure activity usually has a favorable outcome, the aphasia can fluctuate for years. The improvement is more likely in promptly treated cases.

Aphasia↗
PubMed2004

Aphasia after hemispherectomy in an adult with early onset epilepsy and hemiplegia.

A 55 year old left handed man with left hemisphere subcortical encephalomalacia, seizures, language impairment, and right hemiparesis from a motor vehicle accident at age five was evaluated for epilepsy surgery. The patient continued to speak and followed commands during a left intracarotid amobarbital test (IAT). Left functional hemispherectomy resulted in expressive aphasia. Based on postoperative outcome, language was bilateral. The injury after primary development of language function, the predominantly subcortical lesion, and the late timing of surgical intervention well past development and plasticity may have been factors in the emergence of postoperative aphasia.

Accidents, Traffic↗
PubMed2003

Eclectic perspectives on the psychology of aphasia.

This article explores the psychological changes that occur in patients who have suffered a stroke with resulting aphasia and examines the adjustments necessary to help the patient cope. The eclectic approach described in this paper examines the psychology of aphasia from three perspectives: effects of brain injury, psychological defenses and coping styles, and responses to loss. Depression, anxiety attacks, ego restriction, crying, euphoria, denial, anger, and a host of other psychological reactions can accompany stroke, sometimes causing health care personnel to feel overwhelmed by these psychological concomitants in their patients. This paper is intended as a guide to understanding the significant psychological adjustments many patients must undergo. Current information is provided to assist in evaluating and treating these patients.

Adaptation, Psychological↗
PubMed2003

Functional Outcome Questionnaire for Aphasia: overview and preliminary psychometric evaluation.

OBJECTIVE: To perform a preliminary evaluation of a questionnaire designed to assess functional outcomes of treatment for aphasia. METHODS: The Functional Outcome Questionnaire for Aphasia (FOQ-A) is an inventory consisting of 32 caregiver-completed items rating the person with stroke's ability to perform various communication behaviors on a 5-point scale. The total score for the FOQ-A is reported as a mean of all completed items. The FOQ-A was administered by research assistants to caregivers of patients with left hemisphere stroke (n = 18). RESULTS: The FOQ-A showed acceptable initial reliability and validity properties. As predicted, the FOQ-A displayed high positive correlations with standardized functional communication measures. The FOQ-A also showed only weak associations with other measures (health-related quality of life, caregiver strain). CONCLUSIONS: Overall results of our preliminary psychometric examination of the FOQ-A were promising. The findings suggested that the FOQ-A may be a sensitive measure of functional communication abilities and does not appear to be biased heavily by caregiver strain. Plans for further evaluation of the FOQ-A are discussed.

Adult↗
PubMed1992

Assessment of aphasia in relation to communication and cognitive impairments among stroke patients.

Methods for assessing language impairments differ from those needed for communication problems. The article presents results from three previously published studies by the author and co-workers. It is concluded that information about the impairment and training in compensation should be offered the spouse as well as speech therapy to the patient in order to improve reduced communication due to aphasia. Measures of neuropsychological impairments, communication skills and awareness of deficits should be included as well as tests of linguistic competency if a comprehensive aphasia assessment is sought. The methods described are shown to validly differentiate between aphasic subtypes and neuropsychological syndromes.

Aphasia↗
PubMed1992

Aphasia and its relation to language and thinking. Finding alternative ways for communication.

A pictorial computerized communication aid for aphasic patients, PicBox, (12) has been developed by a group in Sweden. During the technical and clinical work with the PicBox program we have had the reason and possibility to reflect on the relation between aphasia, language and thinking. From linguistic and neuropsychological research it has been claimed that in aphasia there is often a general cognitive impairment. Preliminary results from three patients' use of PicBox show that aphasic disturbances can, to some extent, be compensated for by pictorial communication, thus indicating an underlying cognitive competence. There are, however, also data indicating a deeper disturbance leading to an inability to fully use alternatives for spoken or written language.

Aged↗
PubMed2004

[Broca aphasia with neologisms].

Patients with jargon aphasia generally have fluent speech with poor comprehension. However, outstanding jargons may appear in non-fluent aphasics. We report a 69-year-old left-handed woman with non-fluent jargon aphasia due to lesions in the right frontoparietal area. Features of her speech included non-fluent meaningless sequences of syllables, i. e., phonetic jargon, which was obvious in all the tasks including spontaneous speech, repetition, naming and reading. Her utterance was sparse, but not effortful or anarthric. She understood most of spoken single words, but was confused by complex sentences. Brain CTs revealed acute lesions affecting the inferior and middle frontal gyri, insular cortex, precentral and postcentral gyri, and a part of the angular gyrus in the right hemisphere. Old infarcts were also noted in the right frontal pole and prefrontal area. The unique feature of her language impairment suggested somewhat deviated lateralization and localization of her language function.

Aged↗
PubMed1992

Slowly progressive aphasia: report of a case.

We report on the case of a 66-year-old right-handed woman, who shows the clinical and behavioral features of "slowly progressive aphasia" described by MESULAM. At the age of 63 the patient began to develop progressive disturbances of word fluency and naming. The neuropsychological examination revealed amnestic aphasia and a mild impairment of verbal memory. Neuroradiological findings demonstrated left temporo-parietal atrophy. A neuropsychological evaluation performed two years later showed a worsening of language disorders and only a slight compromission in other cognitive areas, while the activities of daily living and the occupational functioning remained unimpaired.

Aged↗