Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “pre-eclampsia”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 919 records · Page 51Linked to original sources

[Perinatal mortality in twin birds (author's transl)].

A retrospective investigation of 146 twin births (1% of all births in our obstetric hospital in 15 years) was presented. Compared with a normal control group, the average age of the women with twin pregnancies was higher on the whole and the number of primaparate was lower. Half of the women had an EPH gestosis. Forty-one percent of the births were premature. Perinatal mortality was 9.5% (first twin: 6.4%; second twin: 13.6%). The higher rate of complications accompanying twin pregnancies during the pregnancy itself and during the birth make intensive supervision necessary.

Adult↗

The management of severe preeclampsia and eclampsia with intravenous diazoxide.

Twelve patients with either severe preeclampsia (9) or eclampsia (3) were treated with intravenous diazoxide, 300-mg bolus, for the reduction of diastolic blood pressure (less than or equal 110 torr) after the usual and customary measures had been initiated to include parenteral MgSO4 and diazepam. Diazoxide precipitously decreased both systolic and diastolic blood pressure proportionately (35-50%); the nadir was invariably reached in 5-15 minutes. Diastolic pressure never fell below 50 torr, and mean arterial pressure always exceeded 70 torr. Oliguria was not apparent. The vasodepressor response was fairly persistent for 4 hours in all but 3 patients; 2 of these received a second 300-mg dose. Significant changes in fetal heart activity (bradycardia, dysrhythmia) were observed in only 1 patient. Labor was immediately ablated in all patients, but could be restimulated with oxytocin. All pregnancies were terminated within 7 hours (mean, 3.7 hours), seven of them by cesarean section. Eleven newborns did well. We conclude that the immediate reduction in maternal arterial blood pressure is without apparent hazard to the mother as well as the fetus.

Adolescent↗

Effects of magnesium sulfate on toxemic patients in labor.

One hundred forty-four toxemic patients were studied by continuous electronic maternal and fetal monitoring. Ninety-seven were treated by intravenous bolus of 2 g MgSO4 every 1-2 hours, and 47 by intravenous drip MgSO4 at a rate of 1 g/hour. Clinical doses of MgSO4 do not affect maternal ECG, temperature, uterine contractions, or fetal heart rate. Intravenous bolus administration is frequently associated with slowing of maternal respirations and hypotension and occasionally with transient apnea.

Body Temperature↗

Hypertension in pregnancy and perinatal mortality.

The effect of various forms of hypertension on perinatal mortality has been investigated. Non-essential, non-proteinuric hypertension had relatively little effect on perinatal mortality, whereas essential and proteinuric forms of hypertension had a marked influence. Diastolic blood pressures of less than 110 mmHg did not influence perinatal mortality. Fetal loss from hypertensive disease was largely accounted for by fetoplacental inadequacy, accidental haemorrhage and preterm delivery. Management more suited to individual needs and induction of labour, once biological and lung maturity has been achieved, is advocated.

Adolescent↗

[Clinico-diagnostic features of hemorrhagic strokes in late toxemias of pregnancy].

The paper deals with clinical studies concerning 128 cases of hemorrhagic strokes which complicated the development of a pregnancy with late toxicosis (nephropathy, preeclampsia, eclampsia). The pathogenesis of cerebral hemorrhages is discussed in relation to disturbances of hemodynamics and the coagulative blood system and is confirmed by the data of mechanocardiography and indices of blood coagulation. The author gives a clinical description of different forms of the hemorrhagic syndrome (hemorrhage of the retina, into the subcutaneous fat, gastric, renal-vesicular, nasal uterine hemorrhages). The author also discusses correlations with cerebral hemorrhages. Their clinical and diagnostical significance are determined along with the use of coagulant therapy of such cases.

Adolescent↗

Fetal movements in utero: nature, assessment, prognostic value, timing of delivery.

Fetal movements in utero are an expression of fetal well-being. However, a sudden increase of fetal movements is a sign of acute fetal distress, such as in cases of cord complications or abruptio placentae. Decreased fetal movements are seen in cases of chronic fetal distress such as preeclampsia, hypertension in pregnancy, etc. It was shown that in these cases a pronounced decrease up to cessation of fetal movements occurred before fetal death in utero while fetal heart beats were still audible for at least 12 hours. This situation was called "movements alarm signal" (MAS). This sign points to a severely disturbed fetus and indicates impending intrauterine fetal death. Such a development is an indication for immediate delivery of the fetus, provided it is viable. High-risk pregnant women are instructed to assess and record fetal movements daily as a monitor of fetal condition. A special device which records fetal movements is used to confirm the women's assessment of fetal movement. It was shown that fetal movement monitoring was found to be more reliable than the urinary estriol determination in predicting impending fetal death in utero. It was also shown that in cases of MAS, fetal heart rate (FHR) changes will appear 1 to 4 days after the MAS has appeared. Meconium was found in only 50% of these cases. Increased fetal movements are manifested as a response to various stimuli such as sound, light, touch, and ultrasound. Classification of high-risk pregnancies into 3 groups according to the hormone assays, enzyme assays, ultrasonic cephalometry, fetal movements, and FHR is suggested.

Acoustic Stimulation↗