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PubMed1996

When anthropology meets epidemiology: using social representations to predict drinking patterns.

Based on a sample of 2,015 adult drinkers from the Montreal metropolitan area (Quebec, Canada), this study investigates the relationship between eight social representations of drinking (i.e., compensatory, convivial, relaxing, disinhibitory, harmful, sexually enhancing, conventional, socially enabling) and drinking measures (QF Index, drinking frequency, and maximum number of drinks on one occasion) according to age and sex. The representations explain up to 34% of the variance in drinking measures. Representations differed in the strength of their relation to drinking measures and in population prevalence. Strength of relation to drinking and prevalence rates were relatively independent. Representations were generally more strongly endorsed by men than women, although they were related in the same way to drinking behaviors. Representations were also more strongly endorsed by younger than by older respondents, and they related differently to drinking in each age group. The implications of these results for prevention are discussed.

Adolescent↗
PubMed2005

Alcohol and risk for ischemic stroke in men: the role of drinking patterns and usual beverage.

BACKGROUND: The association of light to moderate alcohol consumption with risk for ischemic stroke remains controversial, as do the roles of beverage type and drinking pattern. OBJECTIVE: To assess the association of drinking patterns and beverage type with risk for ischemic stroke among men. DESIGN: Prospective cohort study. SETTING: United States. PARTICIPANTS: 38 156 male health professionals who were free of known cardiovascular disease or cancer at baseline in 1986. MEASUREMENTS: With a semi-quantitative food-frequency questionnaire, the authors individually ascertained consumption of regular and light beer, red and white wine, and liquor every 4 years. Alcohol consumption was categorized as light (0.1 to 9.9 g/d, or <1 drink daily), moderate (10.0 to 29.9 g/d, or 1 to 2 drinks daily), and heavier (> or =30.0 g/d, or > or =3 drinks daily). RESULTS: During a follow-up period of 14 years, 412 cases of incident ischemic stroke were documented. Compared with abstainers, light drinkers had a multivariate-adjusted relative risk of 0.99 (95% CI, 0.72 to 1.37), moderate drinkers had a multivariate-adjusted relative risk of 1.26 (CI, 0.90 to 1.76), and heavier drinkers had a multivariate-adjusted relative risk of 1.42 (CI, 0.97 to 2.09; P = 0.01 for trend). Consumption of 10.0 to 29.9 g of alcohol per day on 3 to 4 days per week appeared to be associated with the lowest risk (relative risk, 0.68 [CI, 0.44 to 1.05]). Red wine consumption was inversely associated with risk in a graded manner (P = 0.02 for trend), but other beverages were not. The apparently higher risk for ischemic stroke with heavier alcohol use appeared to be most pronounced for the embolic subtype. LIMITATIONS: This study had limited power to examine specific drinking patterns and heavy drinking and could not assess risk for hemorrhagic stroke. CONCLUSIONS: In this sample of male health professionals, light and moderate average alcohol use was generally not associated with an increased risk for ischemic stroke, although drinking pattern and beverage type modified this relation. Intake of more than 2 drinks per day may be associated with a higher risk for ischemic stroke.

Adult↗
PubMed1999

Evaluation of the Yale-Brown Obsessive Compulsive Scale (YBOCS-hd) for heavy drinking with mild to moderately dependent alcohol abusers.

BACKGROUND: Many similarities have been noted between urges and desires to drink heavily and obsessive-compulsive disorders (OCD). Based on such similarities, Modell et al. (1992) developed the Yale-Brown Obsessive Compulsive Scale for heavy drinking (YBOCS-hd), a modified version of YBOCS, to assess obsessions and compulsions related to heavy drinking. Evaluation of the YBOCS-hd has been limited to more severely dependent alcohol abusers. METHODS: The present study used a self-administered version of the YBOCS-hd to evaluate (1) the severity of drinking-related obsessive compulsive symptoms with mild to moderately dependent alcohol abusers (problem drinkers), and (2) whether end-of-treatment changes in YBOCS-hd scores would be related to within-treatment functioning. RESULTS: Results indicated that problem drinkers have lower alcohol-related Obsessive and Compulsive subscale scores than did more severely dependent drinkers, but higher scores than did non-problem drinkers, supporting the construct validity of the YBOCS-hd. In addition, at the end of treatment, the YBOCS-hd scores of alcohol abusers who drank at low-risk levels during treatment were significantly lower than the scores of those who drank at high-risk levels. Lastly, exploratory factor analysis did not provide support for the two purported YBOCS-hd subscales (Obsessive, Compulsive). Instead, the analysis yielded a single general factor and a second factor that contained two questions measuring heavy drinking. CONCLUSIONS: Despite the fact that total YBOCS-hd scores covaried with drinking, neither the total YBOCS-hd pretreatment score nor the two subscale scores predicted functioning at the end of treatment. The present results call into question the utility of the YBOCS-hd, because a single item measuring the heaviness of drinking was as useful as the total YBOCS-hd and its two subscales in relating changes during treatment to end-of-treatment functioning for problem drinkers. However, although the YBOCS-hd does not predict changes in drinking, it may have value as an indirect measure of drinking in situations where direct measurement of alcohol consumption is undesirable (i.e., direct measurement might be reactive). Because the present findings are derived from problem drinkers, further research is needed to confirm the factor structure of the YBOCS-hd with clients who represent a broader range of alcohol problem severity.

Adult↗
PubMed2001

Family interactions of alcoholics as related to alcoholism type and drinking condition.

BACKGROUND: Several studies have reported that the marital interactions of antisocial and aggressive, versus nonantisocial and nonaggressive, alcoholics exhibit higher rates of aversive-defensive communications and higher levels of negative reciprocity. To extend these findings, we examined the effect of alcoholism type (high- versus low-antisocial alcoholics: HAS, LAS) and drinking condition on family communication patterns. METHODS: Marital and parent-child dyads from 100 alcoholic families were videotaped while they discussed personally relevant issues during drinking and no-drinking sessions (no children were offered any alcohol). All interactions were coded with the Marital Interaction Coding System, and the data were assessed for differences in rate of positive, negative, and problem-solving behaviors, as well as sequential structures. RESULTS: HAS couples were more negative during the drink versus no-drink condition, whereas drinking did not affect negativity for LAS couples. In addition, the negative communications of HAS versus LAS alcoholics were more likely to increase spouse negativity during the drink versus no-drink condition. Group differences for parent-child interactions were few. CONCLUSIONS: The nature of family interactions was related to both alcoholism type and alcohol consumption, and the marital interactions of alcoholism types could be differentiated on the basis of the frequency and sequential structure of negative exchanges. It is most important to note that it is the interactions of the HAS alcoholic that undergo the most change as a function of drinking condition, with little support for the "adaptive consequences" hypothesis that alcohol consumption leads to more effective problem-solving for couples in which the alcoholic exhibits fewer antisocial and more internalizing characteristics. Study limitations and directions for future research are discussed.

Adolescent↗
PubMed2002

Drinking-driving as a component of problem driving and problem behavior in young adults.

OBJECTIVE: This study replicated and extended a conceptual model of drinking-driving and its relationship to other problem behavior to determine (1) if the model characterized the problem driving and problem behavior of young adults from the general population and (2) if the model applied to women as well as to men. METHOD: Telephone survey data (measures of drinking-driving, drug-driving, risky driving, problem drinking, drug use and delinquent behavior) collected from young adults (N = 4,230, 53% female) were used in structural equation modeling. Two models were developed--one for problem driving and one for problem behavior--each testing the structural associations among latent variables and testing them as latent indicators of common second-order latent variables. RESULTS: The results supported the hypothesis that drinking-driving (along with problem drinking, drug use and delinquent behavior) is an indicator of problem behavior in the general population sample. Also, drinking-driving, drug-driving and risky driving were demonstrated to be indicators of a common construct: problem driving. The models fit the data equally well for both young men and young women, and a crossvalidation conducted on an independent sample confirmed the results. CONCLUSIONS: The results provide empirical support for the inclusion of drinking-driving and problem driving in an extended model of Problem Behavior Theory. Drinking-driving, drug-driving and risky driving all relate to a common construct: problem driving. These results have important implications for research and for interventions to treat or prevent drinking-driving, especially among young adults.

Adult↗
PubMed2005

Sports drinks and dental erosion.

PURPOSE: To discuss the composition and rationale for the use of sports drinks along with recent studies investigating the relationship between sports drinks and dental erosion. METHODS: A review of the literature of sports drinks and dental erosion was done. RESULTS: For most athletes and individuals engaged in physical activity, the use of sports drinks does not provide a benefit over water. Furthermore, although there is much in vitro evidence that acidic drinks such as wine, fruit juices and carbonated soft drinks have erosive potential and there are relationships between consumption of these drinks and erosion, only one study has reported an association between sports drinks and dental erosion. Other factors such as drinking habit and salivary production may be more important determinants of dental erosion.

Beverages↗
PubMed2005

[Nationwide survey of alcohol drinking and alcoholism among Japanese adults].

PURPOSE: To investigate the characteristics of alcohol use among Japanese adults and prevalence of alcohol dependence in Japan, we conducted a nationwide survey on alcohol drinking behavior and alcohol dependence among Japanese adults using a representative sampling method. METHODS: We sampled 3500 adults from throughout the entire country using a stratified random sampling method with two-step stratification, and carried out a home visit interview survey. A total of 2547 people (72.8%) responded to the survey. The survey period was June, 2003. The questionnaire contained questions about the frequency and quantity of alcohol use, 'hazardous use of alcohol' and 'alcohol dependence' according to the ICD-10 definition, several screening scales on problem use of alcohol (CAGE, KAST, AUDIT), life-time prevalence of 24 alcohol related diseases, smoking status, dysgryphia, and nightcap drinking. RESULTS: The number of respondents was, 1184 males, and 1363 females. Lifetime alcohol drinking, and weekly drinking, and daily drinking rates were 95.1%, 64.4%, and 36.2% for males, 79.0%, 27.5%, and 7.5% for females, respectively. Average daily alcohol consumption was 3.7 units for males, and 2.0 units for females (1 unit = 10 g pure alcohol). The proportion of drinkers who drank alcohol 4 units or more daily was 28.9% for males, and 7.6% for females, and that for 6 units or more was 12.7% for males, and 3.4% for females. The proportion of flasher was 41.2% for males, and 35.0% for females. Among screening questions, problem drinking was most frequently identified using AUDIT (score 12 points or more, 150 persons), followed by KAST (2 points or more, 100 persons) and CAGE (2 points or more, 98 persons). The number of subjects who met the ICD-10 criteria for alcohol dependence was 24, while the number who engaged in hazardous alcohol use was 64. CONCLUSIONS: This study revealed that problem drinking and alcohol dependence are a serious problem in Japanese general population. The problem of females drinking may be growing. The government should emphasize the prevention of alcohol drinking problems in adults and continue the conduct of nationwide prevalence surveys to monitor the problem.

Adult↗
PubMed1990

[An investigation into the actual condition of the sports drink intake on children].

The purpose of this study was to investigate the actual condition of the sport drink intake on children. We conducted an investigation by means of questionnaires at 3 nursery schools and a day nursery in and around Hiroshima City, and using 505 answers with the comparison between 4 areas. The following results were obtained: 1) Less than 10% of the children often took sport drinks and about 70% of the children sometimes. 2) In response to the question of when taken, 40-50% of answers revealed that the drinks were taken when the children ill and 20-40% of answers were take from home. 3) In response to the question as to why children begin to take the drinks, many parents answered that they were advised by a doctor and a nurse to give their child sport drinks to prevent for dehydration, when their children were ill. This answer accounted for about 60% of the answers to this question. 4) Parents imagined that fruit drinks, carbonated beverages and beverages with lactic acid promoted tooth decay. Also the image of cariogenicity was less than 100% fruit juices, home-made juices, sport drinks, cow milks and water or tea in that order. The results suggest that parents regard sport drinks as beverages which do not promote tooth decay and give their child sport drinks frequency.

Beverages↗
PubMed1996

Public knowledge and attitudes towards the use of alcohol and drinking guidelines.

AIMS: To investigate public knowledge and attitudes towards the use of alcohol with particular focus on drinking guidelines. METHOD: A telephone survey of 249 people randomly selected from the toll free area of Christchurch. RESULTS: Three key findings were (1) not one respondent was able to quote drinking guidelines that included quantities of alcohol per occasion or quantities of alcohol per week; (2) the majority of the public (74%) thought drinking guidelines were not publicised well enough; and (3) young men (18-24 years) were significantly more likely to state incorrectly that greater than six standard drinks is a safe amount of alcohol to consume on social occasions. CONCLUSIONS: More active promotion of drinking guidelines via the electronic and popular print media should be considered. Young men require particular attention related to drinking no more than six standard drinks per occasion of drinking as part of this initiative. Other studies targeting groups such as the more transient, different ethnic groups especially Maori and Pacific Islanders, health professionals and people with alcohol problems would be of interest, as well as a repeat of this study following an interim period in which active promotion of drinking guidelines is undertaken.

Adolescent↗
PubMed1997

Situational norms for drinking and drunkenness: trends in the US adult population, 1979-1990.

Drinking depends on time, place, situation and personal characteristics. Patterns and trends in situational drinking norms (subjective levels of acceptable consumption for various situations) for US adults are reported. Results are based on eight comparable normative questions from national household surveys conducted in 1979 (n = 1772), 1984 (n = 5221 including Hispanic and black oversamples) and 1990 (n = 2058). Across years and population subgroups, a correspondence in ordering of situations on acceptability of drinking and of drunkenness was found. There were contrasting secular trends in the acceptability of drunkenness in different situations: drinking "enough to feel the effects" became more acceptable when at home but less acceptable in several other situations, particularly for men at a bar. For a decreasing percentage of respondents of both genders, it remains more acceptable for men than women to drink in bars, but gender norms in such "wetter" situations were converging by 1990. Men remain more accepting of drinking (but not drunkenness) for "dryer" situations such as when driving, but the trend is towards reduced acceptance. Multiple regression models predicting "acceptance of drinking" and "acceptance of drunkenness" scores showed fair stability in explanatory variables over time, with drinking level and conservative Protestant affiliation (drinking) or age (drunkenness) the major contributors.

Adult↗
PubMed1998

Sensitivity of hypothalamic paraventricular nucleus to C- and N-terminal angiotensin fragments: vasopressin release and drinking.

We studied the effect of angiotensin (ANG) peptides and their C- and N-terminal fragments, microinjected bilaterally into the hypothalamic paraventricular nucleus (PVN) of male Wistar rats, on arginine vasopressin (AVP) release into the blood and drinking. ANG II (1-8) and the C-terminal ANG III (2-8) at 0.1-100 pmol/200 nl induced a dose-dependent increase in AVP release with a maximum of 26.45+/-6.0 and 31.86+/-7.0 pg/ml, respectively, vs 1.6+/-2.0 pg/ml in vehicle treated controls (P<0.001). The highest dose of ANG II and ANG III also induced drinking responses of 4.3+/-0.78 and 2.91+/-0.54 ml water/15 min, respectively. Bilateral pretreatment of the PVN with the AT1 receptor antagonist losartan (4 nmol/200 nl) inhibited ANG II- and ANG III-induced AVP release and drinking. Different doses of the C-terminal ANG IV (3-8), ANG (4-8) or ANG (5-8) peptides did not induce AVP release or drinking. The N-terminal ANG (1-7) peptide induced a dose-dependent increase in AVP release (maximum 8.5+/-3.5 pg/ml after 100 pmol) but the effect was much less potent than that induced by the same dose of ANG II or ANG III. ANG (1-7) failed to induce a drinking response. Pretreatment of the PVN with losartan or the AT2 receptor antagonist, PD 123177 (4 nmol/200 nl), inhibited the 100 pmol ANG (1-7)-induced AVP release. The N-terminal ANG (1-4) peptide did not affect AVP release or drinking at any dose tested. Our data demonstrate that the C-terminal ANG II (1-8) and ANG III (2-8), but not shorter fragments, can induce AVP release and drinking response via AT1 receptors in the PVN. The N-terminal ANG (1-7) was less potent in stimulating AVP release than ANG II or ANG III and had no influence on drinking. Thus, the presence of both arginine2 and phenylalanine8 in the angiotensin peptide sequence appears to be important to elicit AVP release and drinking from the PVN in vivo.

Angiotensin II↗
PubMed1998

Ten-year prediction of women's drinking behavior in a nationally representative sample.

This study evaluates how well women's personal and social characteristics predict their drinking behavior over a 10-year period, using data from a national representative sample of 696 U.S. women interviewed in 1981 and 1991. Interviews obtained data on drinking behavior, personality characteristics, childhood and recent experiences, and perceptions of the social environment. Analyses using paired comparisons, correlations, and linear and logistic regression found that women's alcohol use and its adverse consequences in 1991 were predicted by age, 1981 drinking behavior, and many other aspects of their lives measured 10 years before. Heavier and riskier drinking patterns were associated in particular with adverse childhood experiences, missing interpersonal ties, and expected self-expressive benefits of drinking. However, no variables predicted all patterns of drinking behavior, and specific predictors of different drinking patterns showed little overlap. We conclude that many aspects of women's lives, and particularly their interpersonal relationships, have long-term influences on their drinking behavior, but different patterns of drinking behavior have different antecedents.

Adult↗
PubMed2003

Pediatric neurobehavioral diseases in Nevada counties with respect to perchlorate in drinking water: an ecological inquiry.

BACKGROUND: Contamination of drinking water with perchlorate, a known thyrotropic agent, has been demonstrated in areas in the western United States. The health consequences of that exposure have been studied, particularly in the State of Nevada. Previous studies in Nevada, comparing the area with perchlorate in the drinking water and the areas without perchlorate in the drinking water, have found no difference in neonatal thyroxine (T(4)) or thyrotropin (TSH) levels, or in the prevalences of thyroid diseases and thyroid cancer. This same study design has now been applied to the major neurobehavioral diseases of childhood (i.e., attention deficit-hyperactivity disorder (ADHD) and autism) and to school performance in order to determine whether those conditions are more frequent in the area with perchlorate-contaminated water. METHODS: Medical services data on ADHD and autism were obtained from the Nevada Medicaid system for the period of January 1, 1996, to December 31, 2000, with county of residence used as the basis for residential information. Analyses of fourth-grade school performance results for two recent time periods came from the state government. Perchlorate concentrations in drinking water had been determined by local water authorities. ADHD and autism rates for the area with perchlorate in the drinking water (Clark County) were calculated and compared with the rates for the other areas in the state, as were fourth-grade school performances. RESULTS: Analysis of the data from the Nevada Medicaid program shows that the rates for ADHD and for autism in the area where perchlorate was in the drinking water did not exceed the rates in those areas where there was no perchlorate contamination in the drinking water. Fourth-grade standardized test results for students in Clark County were not different from those of the remainder of the state. CONCLUSIONS: This ecological study of children in the exposure area did not find evidence of an increased risk of either ADHD or of autism caused by perchlorate contamination in the drinking water. Furthermore, no difference in overall fourth-grade school performance was observed. No evidence was found that children from the area with perchlorate in the drinking water (up to 24 microg/liter) had either an increase in pediatric neurobehavioral disease (ADHD and autism) or a decrease in fourth-grade academic performance. The limitations of this ecological study relate to diagnostic criteria and ascertainment of geographic and demographic differences and to data on individual residence and water consumption during pregnancy.

Attention Deficit Disorder with Hyperactivity↗
PubMed1993

Relations of work stress to alcohol use and drinking problems in male and female employees of a computer factory in Japan.

To examine the effects of work stressors on alcohol use and drinking problems as well as a model of stress-induced drinking in Japanese male and female workers, a total of 2581 employees of a computer factory were surveyed using mailed questionnaires. Five psychosocial work stressors, overtime, rotating shift, frequency of drinking, amount of alcohol consumed per drinking occasion, and drinking problems, and depressive symptoms were assessed. The hierarchical linear and logistic regression analyses were conducted in 1043 male and 255 female current drinkers aged 20 years or older. The results suggested that overtime and lack of intrinsic work rewards are main factors for heavy and problem drinking in Japanese male workers and that ambiguity about job future is a factor for heavy drinking in Japanese female workers. However, the model of stress-induced drinking was supported neither in males nor in females, suggesting that the effects of these work stressors on heavy and problem drinking are not mediated by depressive symptoms.

Adult↗
PubMed2000

Muscle glycogen resynthesis rate in humans after supplementation of drinks containing carbohydrates with low and high molecular masses.

The rate of muscle glycogen synthesis during 2 and 4 h of recovery after depletion by exercise was studied using two energy equivalent carbohydrate drinks, one containing a polyglucoside with a mean molecular mass of 500 000-700 000 (C drink), and one containing monomers and oligomers of glucose with a mean molecular mass of approximately 500 (G drink). The osmolality was 84 and 350 mosmol. l(-1), respectively. A group of 13 healthy well-trained men ingested the drinks after glycogen depleting exercise, one drink at each test occasion. The total amount of carbohydrates consumed was 300 g (4.2 g. kg(-1)) body mass given as 75 g in 500 ml water immediately after exercise and again 30, 60 ad 90-min post exercise. Blood glucose and insulin concentrations were recorded at rest and every 30 min throughout the 4-h recovery period. Muscle biopsies were obtained at the end of exercise and after 2 and 4 h of recovery. Mean muscle glycogen contents after exercise were 52.9 (SD 27.4) mmol glycosyl units. kg(-1) (dry mass) in the C group and 58.3 (SD 35.4) mmol glycosyl units. kg(-1) (dry mass) in the G group. Mean glycogen synthesis rate was significantly higher during the initial 2 h for the C drink compared to the G drink: 50.2 (SD 13.7) mmol. kg(-1) (dry mass). h(-1) in the C group and 29.9 (SD 12.5) mmol. kg(-1) (dry mass). h(-1) in the G group. During the last 2 h the mean synthesis rate was 18.8 (SD 33.3) and 23.3 (SD 22.4) mmol. kg(-1) (dry mass). h(-1) in the C and G group, respectively (n.s.). Mean blood glucose and insulin concentrations did not differ between the two drinks. Our data indicted that the osmolality of the carbohydrate drink may influence the rate of resynthesis of glycogen in muscle after its depletion by exercise.

Adult↗
PubMed2006

Rapid analysis of taurine in energy drinks using amino acid analyzer and Fourier transform infrared (FTIR) spectroscopy as basis for toxicological evaluation.

So-called energy drinks with very high amounts of taurine (up to 4000 mg/l are usually granted by certificates of exemption) are increasingly offered on the market. To control the currently valid maximum limits of taurine in energy drinks, a simple and rapid analytical method is required to use it routinely in food monitoring. In this article, we describe a fast and efficient analytical method (FTIR-spectroscopy) that is able to reliably characterize and quantify taurine in energy drinks. The determination of taurine in energy drinks by FTIR was compared with amino acid analyzer (ion chromatography with ninhydrin-postcolumn derivatization). During analysis of 80 energy drinks, a median concentration of 3180 mg/l was found in alcohol-free products, 314 mg/l in energy drinks with spirits, 151 mg/l in beer-containing drinks and 305 mg/l in beverages with wine. Risk analysis of these products is difficult due to the lack of valid toxicological information about taurine and its interferences with other ingredients of energy drinks (for example caffeine and alcohol). So far, the high taurine concentrations of energy drinks in comparison to the rest of the diet are scientifically doubtful, as the advertised physiological effects and the value of supplemented taurine are unproven.

Adult↗
PubMed1988

Genotoxic activity of organic chemicals in drinking water.

The information summarized in this review provides substantial evidence for the widespread presence of genotoxins in drinking water. In many, if not most cases, the genotoxic activity can be directly attributed to the chlorination stage of drinking water treatment. The genotoxic activity appears to originate primarily from reactions of chlorine with humic substances in the source waters. Genotoxic activity in drinking water concentrates has been most frequently demonstrated using bacterial mutagenicity tests but results with mammalian cell assay systems are generally consistent with the findings from the bacterial assays. There is currently no evidence for genotoxic damage following in vivo exposures to animals. In some locations genotoxic contaminants of probable industrial and/or agricultural origin occur in the source waters and contribute substantially to the genotoxic activity of finished drinking waters. The method used for sample concentration can have an important bearing on study results. In particular, organic acids account for most of the mutagenicity of chlorinated drinking water, and their recovery from water requires a sample acidification step prior to extraction or XAD resin adsorption. Considerable work has been done to determine the identity of the compounds responsible for the mutagenicity of organic concentrates of drinking water. Recently, one class of acidic compounds, the chlorinated hydroxyfuranones, has been shown to be responsible for a major part of the mutagenic activity. Strategies for drinking water treatment that have been evaluated with respect to reduction of genotoxins in drinking water include granular activated carbon (GAC) filtration, chemical destruction, and the use of alternative means of treatment (i.e., ozone, chlorine dioxide, and monochloramine). GAC treatment has been found to be effective for removal of mutagens from drinking water even after the GAC is beyond its normal use for organic carbon removal. All disinfectant chemicals appear to have the capacity of forming mutagenic chemicals during water treatment. However, the levels of mutagenicity formed with the alternative disinfectants have been generally less than those seen with chlorine and, especially in the case of ozone, highly dependent on the source water.(ABSTRACT TRUNCATED AT 400 WORDS)

Humans↗
PubMedDate not supplied

Drinking style of parents of alcoholic and control probands.

One aspect of the familial component of alcoholism is the use of alcohol among the parents of affected individuals. Both the individual and concordant drinking styles of the parents of 291 inpatient alcoholic probands and 71 non-alcoholic control subjects were measured using family history methods. Social drinking was almost twice as prevalent among fathers of controls compared to fathers of alcoholics. Problem drinking was more than twice as prevalent among the fathers of alcoholics compared to fathers of controls. The abstinence rate for fathers of both groups was similar. Mothers' drinking styles were similar to the fathers' pattern for both groups. Concordance of drinking style in the parental pair was examined. Similarity in drinking style for the parents of control probands was greatest for social drinking. For parents of alcoholic probands high concordance was also found by problem drinking. Overall a great similarity in drinking style was found for the parents of control probands compared to the parents of alcoholic probands.

Adult↗