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Thoracoscopy in the management of hemothorax and retained blood after trauma.

Retained hemothorax complicated by blood clotting in the thoracic cavity traditionally has been treated with open thoracotomy for evacuation of the hemothorax and cleaning of the thoracic cavity. Recent improvements in video technology and endoscopic surgical instruments have fostered renewed interest in video-assisted thoracoscopic surgery to diagnose and treat a variety of surgical conditions of the chest, which classically were managed exclusively by thoracotomy. Posttraumatic retained hemothorax currently is being managed at most institutions by video-assisted thoracoscopic surgery, with consistently good results.

Female↗

Development of steerable instruments for minimal invasive surgery in modular conception.

The augmenting complexity of minimal invasive interventions requests a continuous improvement of technologies. Extended endoscopic procedures, e.g. laparoscopic-transanal sigmoidectomy or thoracoscopic esophagus dissection require difficult surgical manipulations like mobilisation, sceletonization as well as ligatures and sutures. They are difficult to perform with the present endo-surgical instruments. A major instrumental weakness is represented by the restricted steerability because of the rigid shaft axis and the resulting low degrees of freedom (DOF). Therefore a series of steerable flexible instruments has been developed in interdisciplinary cooperation between surgeons and engineers. The prototypes provide a multi-joint working as the instrument's elbow, which allows to incline the tip around +/- 280 degrees. The second additional DOF is the rotation of the surgical tool. The prototypes have been experimentally tested in laparoscopy and thoracoscopy, showing a clear improvement in the carrying out of complex operative manipulations. The further development is performed in modular conception, including electric drives.

Animals↗

Radical retropubic prostatectomy.

Historically, radical prostatectomy is a surgical technique associated with significant morbidity. The ability to minimize intraoperative bleeding and preserve continence and potency requires a comprehensive understanding of pelvic anatomy, meticulous surgical technique, and appropriate surgical instruments. The anatomic radical retropubic prostatectomy first described by Walsh in 1982 represents a technique in evolution. The detailed surgical approach for anatomic radical retropubic prostatectomy described in this article represents the author's technique that has been developed after performing over 2,000 radical prostatectomies since 1986. The step by step illustrations and description of technique are designed to aid the urologic surgeon develop an efficient approach to this surgical procedure.

Humans↗

A novel procedure for mediastinal vagotomy inhibits neurogenic inflammation in rat bronchial tree.

Tachykinin-containing sensory axons originating from the cervical vagal nerves and the first several pairs of thoracic spinal nerves are involved in neurogenic inflammation evoked by capsaicin in the bronchial tree. Unilateral degeneration of the cervical vagal trunk by surgical lesion inhibits neurogenic inflammation in the ipsilateral bronchial airways. The vagal trunk has two main branches, the thoracic vagus nerve and recurrent laryngeal nerve in the thorax. The main purpose of this study was to determine whether the thoracic vagus nerve or recurrent laryngeal nerve was significantly involved in the neural control of bronchial inflammation in the rat. A novel and safe surgical procedure was used for selectively cutting the right thoracic vagal trunk, thoracic vagus nerve, or recurrent laryngeal nerve by introducing the surgical instrument through an aperture between the first and second ribs in the ventral wall of the rostral mediastinum. This surgical operation could be completed without causing a pneumothorax. After 2 postoperative weeks, the effects of denervation on capsaicin-induced plasma extravasation in the respiratory tract were tested. Either right thoracic vagal trunk transection or thoracic vagus section significantly decreased plasma extravasation in the right bronchial tree. Thoracic vagus section was obviously more effective. Evans blue extravasation in the right lobar bronchi was reduced by 44-78% after thoracic vagal trunk transection, while that in the right mainstem and lobar bronchi was reduced by 58-81% after thoracic vagus section. Area densities of India ink-labeled leaky blood vessels in the right lobar bronchi were reduced by 40-65% after thoracic vagal trunk transection, and those in the right mainstem and lobar bronchi were reduced by 83-88% after thoracic vagus neurectomy. Recurrent laryngeal neurectomy did not change the plasma extravasation induced by capsaicin in the trachea and bronchi. These results suggest that capsaicin-sensitive fibers running in the vagal trunk, which largely mediated neurogenic inflammation in the bronchial tree, were projected into the thoracic vagus nerve which, in turn, sent these nerve fibers to the ipsilateral bronchial tree. For the trachea, the remaining sensory fibers surviving denervation might provide sufficient tachykinins to trigger neurogenic inflammation.

Animals↗

[The scientific bases of virtual endoscopy].

The recent advances in medical imaging, the avaibility of methods for image analysis and computer graphics, the technological resources provided by microdevices and the design of minimal access surgical procedures have open the road to new concepts. Virtual endoscopy represents one of these emerging areas and points out the applicative potential of three dimensional (3D) imaging. It leads to less invasive diagnosis and therapeutic achievements and provides important cues for education and interventional planning. Image segmentation, visualization, tissue modeling and interactions with surgical instruments are the fundamental components to build clinical applications. They are examined in this paper through 3D navigation systems, surgical simulations and image guided interventions.

Computer Simulation↗

Comparative examination of the accuracy of a mechanical and an optical system in CT and MRT based instrument navigation.

The aim of an intraoperative instrument navigation system is to support the surgeon in the localization of anatomical regions and to guide the use of surgical instruments. An overview of technical principles and literature reports on various navigation systems is provided here. The navigation accuracy (tested on a plastic phantom under simulated operating room conditions) of the mechanical Viewing Wand system and the optical SPOCS system amounts to 1 to 3 mm for computerized tomography (CT) data, with a significant inverse dependence on the layer thickness. The values for magnetic resonance tomography (MRT) data are significantly higher. In regard to the choice of registration points, a statistically inverse dependence exists between the number of points and the distance between the points. During the time period between autumn 1993 and mid-1999, more than 120 clinical applications were performed. The intraoperative accuracy was in the range of < or = 3 mm. Registering the patient position with preoperatively inserted screw markers achieved accuracy values of < or = 2 mm. The instrument navigation technique has proved to be very advantageous for the spatial orientation of the surgeons. The possibility of checking resection borders has opened up new perspectives in tumor surgery. A quality improvement and a reduction of the operational risks as well as a considerable decline in the stress placed on the patient can be expected in the near future due the techniques of computer-assisted surgery.

Humans↗

[Anterior spinal fusion by thoracoscopy. A non-traumatic technique].

PURPOSE OF THE STUDY: Video assisted thoracic surgery (VATS) is a new modality which allows visualization of, and access to the intrathoracic organs without thoracotomy. Recently, this technique has been used for anterior thoracic spine approach to perform surgery which previously required standard postero-lateral thoracotomy. The authors report their initial experience of anterior spinal fusion using thoracoscopy and give a detailed description of their surgical procedure. MATERIAL AND METHODS: This technique, started on June 1993, was performed only in one level 1 in 10 patients who had thoracic spine trauma with fracture or luxation. The procedure was performed in the lateral decubitus position. The patient was prepared in the standard manner for a full thoracotomy. Surgical instruments that are needed for conversion to an open procedure must be in the operative room. Ventilation was stopped to the ipsilateral lung. Lung's collapse of the surgical side was obtained with a double lumen tube. Carbon dioxide (CO2) insufflation was used to further collapse. The first thoracoscopic portal was placed through the sixth or seventh intercostal space in the posterior axillary line, which was the safest place. All subsequent portals were placed under thoracoscopic visualization, in a triangular way as recommended by Landreneau (1992). Only open trocars were used to avoid complication of CO2 insufflation. Once the target level has been defined, a needle was placed into the disc space and roentgenographic confirmation obtained. The parietal pleura was then divided using monopolar electrocautery. Segmental vessels of the operation field lied transversely across the midportion of the vertebral body. They were mobilised and systematically ligated with endoscopic clip to simplify the procedure. Then the intervertebral space was opened and bone and disc were removed, restricted to the anterior and middle third. The graft was placed into the thoracic cavity by using a high density calcium hydroxyapatite ceramic block. Peroperative radiologic control ascertained the good position of the implant. At the end of the procedure a chest tube was placed through the lower trocar site and the lung re-expanded. A post operative CT Scan controlled good position of the graft and complete lung expansion. Contra-indications for VATS are previous surgical procedures or empyema causing extensive pleural adhesions. Procedures not appropriate for VATS approach are some that require anterior instrumentation for stabilisation, burst fracture, or fracture with posterior wall involved. RESULTS: The planned procedure was accomplished in all but one patient who required conversion to an open procedure because of segmental artery bleeding. Mean operative time was 1 h 45 mm, and mean estimated blood loss was 650 cc. There was no complication from CO2 insufflation neither postoperative complication. With an average of 2 years follow up, anterior grafting is as good as an open technique, radiologic evaluation according to Uchida (1990) showed good incorporation of each block without any radiolucent line or displacement. DISCUSSION: According to literature this technique was performed safely in 10 cases, especially without any respiratory complications and chronic pain (impairement of pulmonary function, re-expansion failure, incisional complications, rib fractures, chronic pain and malfunction of the chest wall, limitation of shoulder girdle motion) which are considered to be the main disadvantage of traditional thoracotomy. Many authors previously used VATS for multi level thoracic discectomy for correction of spinal deformities (Mack 1995), spinal reconstructive surgery (Mac Afee 1995) or removal of protrude thoracic disc (Rosenthal 1994). CONCLUSION: This original technique demonstrates that thoracoscopy for anterior thoracic surgery is better for the patients, reducing surgical trauma of the chest wall and to the lung parenchyma (in term of post operative comfort, sh

Adult↗

Treatment of colon and rectal cancer.

During the past two decades, remarkable progress has been made in the treatment of cancers of the colon and rectum. Both oncologic and functional outcomes for this disease have improved dramatically. The reasons for the improved patient outcome in this disease include advances in knowledge of the biology of the disease, advances in surgical instrumentation and techniques, and ongoing advances in multimodality therapy, with the use of radiation and chemotherapy as an adjuvant to surgical resection. This review details many of these advances in a comprehensive manner and illustrates the necessity of a multidisciplinary approach for optimizing outcome for patients with these cancers.

Colonic Neoplasms↗

Magnetic resonance imaging and biological changes in injured intervertebral discs under normal and increased mechanical demands.

STUDY DESIGN: An animal model was used to examine the short-term tissue response to changes in the mechanical environment after the structure (disc) is mechanically injured. OBJECTIVES: To observe changes in an injured intervertebral disc and the corresponding motion segment when the mechanical demands of the disc were increased by fusion of the adjacent motion segments. SUMMARY OF BACKGROUND DATA: Disc degeneration has been modeled in animals by producing a tear in the anulus via laminectomy, laparotomy, or posterolaterally. Methods of altering and quantifying the mechanics of the intervertebral joint by use of internal fixation and fusion in the canine have been developed. METHODS: Eight dogs divided into two groups (a study and a control group) had anular stab wounds (L2-L3). The study group was surgically instrumented posteriorly from L3 to L7. Magnetic resonance imaging studies were conducted for all animals before and periodically after the surgical procedures. At the end of the study, the segments were processed histologically and biochemically. RESULTS: Anular bulging was seen on magnetic resonance imaging in all control animals 4 months after injury and did not progress out until 6 months after injury. Similar changes were seen in study animals, but 75% were herniated by 6 months. Histologic changes correlated with magnetic resonance imaging changes. No significant difference in water or proteoglycan content of the disc tissue between groups was found. CONCLUSIONS: Progression from the bulging of the anulus to herniation was not evident in damaged discs not subjected to adjacent fusions. No change in water or proteoglycan content as a function of altered mechanical state was found, suggesting the short-term effect of the altered mechanics is on the mechanical structure and not on the cells or extracellular matrix.

Animals↗

Computer-assisted image-guided surgery using the Regulus Navigator.

The term "frameless image-guided surgery" has become as well-known to surgeons as computerized tomography or operating room microscope over the past several years. The technologies behind this new surgery option include robotic arms, infra-red camera arrays (1D and 2D), ultrasound, robotic microscopes and magnetic field digitizers. The authors have shown the magnetic field technology incorporated in the Regulus Navigator to be a viable, accurate surgeon's tool by first integrating a conventional framed device and magnetic field frameless device, then advancing to the frameless device alone. During surgery a patient's anatomy is first registered to preoperatively acquired radiological data. Surgical instruments are tracked on interactive CT/MRI displays as the surgeon locates his point or volume-in-space within the surgical field and uses his own procedure/technique of choice for surgical treatment. A clinical trial of 221 patients showed an overall mean accuracy of 2.56 mm with a standard deviation of 1.15 mm for intraoperative registration. Major concerns of utilizing magnetic field technology in the operating room, such as interference from surrounding metallic objects and equipment, were proven manageable while maintaining acceptable accuracy.

Humans↗

Microscopic and endoscopic laser surgery.

Lasers have been found to be very practical in improving precision in microsurgery and endoscopic surgery. An optical system by which the tissue and the interacting laser beam can be observed simultaneously under binocular magnification makes possible precise control of the laser beam. The carbon dioxide laser and the neodymium:yttrium-aluminum-garnet laser are both used in laser surgery--the CO2 laser is preferred for cutting and ablating tissues, and the Nd:YAG for coagulation and hemostasis of bleeding blood vessels. Future laser surgical instrumentation will take advantage of the digital information provided by computerized diagnostic equipment to drive a computer-compatible laser surgical system.

Endoscopy↗

Toxicity testing for human in vitro fertilization programs.

Using a mouse embryo culture system, several procedures and materials associated with human in vitro fertilization protocols were tested for potential toxicity. Also, quality-control assays were performed for media prepared by nine different human in vitro fertilization programs. Detrimental effects upon embryo development were observed when culture media were exposed to the following substances: surgical instruments sterilized with Cidex or Cidex-7 or sterilized with ethylene oxide after packaging in Nest Protector Packs, various brands of surgical gloves, and various synthetic materials being evaluated as possible needle or catheter "liners." Results from comparative testing of media and serum supplements prepared by different in vitro programs indicated a wide range in culture medium quality, as assayed by the ability of the reagents to support mouse embryo development. The importance of an animal model system available to all human in vitro programs for routine quality-control analysis and testing of novel uses of materials and innovative methods is discussed.

Animals↗

The principles and use of the neodymium-YAG laser in gynaecological surgery.

The neodymium-yttrium aluminium garnet (Nd-YAG) laser is one of the most recent surgical instruments to be exploited by gynaecologists. This review discusses the manner in which this laser interacts with tissue compared to other surgical lasers. The safety precautions necessary in using this laser are outlined in view of the potential risk of injury to theatre personnel. This is particularly important with respect to the eye. The most valuable application of the Nd-YAG laser to the gynaecologist is its use in ablating the endometrium in cases of menorrhagia. This technique is successful on account of the coagulating properties of this laser. The endometrium is destroyed to a depth sufficient to ablate the basal layer and bleeding is controlled by the coagulation of vessels. Much of the clinical part of this paper deals with this subject, detailing the choice of patients and the particular risks of the technique and discussing some of the problems. Other uses are outlined. Many of these are equally well treated by other and better-established methods. Undoubtedly the future will see many developments and more applications will become apparent.

Colposcopy↗

Functional evidence of reversible ischemic injury immediately after the sympathetic storm associated with experimental brain death.

BACKGROUND: Acute brain death from increased intracranial pressure results in a transient increase in myocardial adenosine and lactate, which indicates that oxygen demand exceeds oxygen delivery during the sympathetic "storm". The aim of this study was to determine the functional significance of this period of ischemia. METHODS: Brain death was inflicted on 40 Westran pigs (36.5-68.0 kg) by inflating a 21-ml subdural balloon over 3 minutes. In 38 animals, micromanometry and sonomicrometry were used to obtain left ventricular pressure-volume loops to determine the preload recruitable stroke work (PRSW) relationship. Data files were recorded before and at 15-minute intervals after beginning balloon inflation. Plasma troponin I was measured before and 60 minutes after beginning balloon inflation in the 38 instrumented and 2 non-instrumented animals. RESULTS: All animals experienced the classical sympathetic storm. The slope of the PRSW relationship decreased, and the volume-axis intercept shifted to the right 15 minutes after beginning balloon inflation (p < 0.0001). Progressive incremental recovery (leftward shift) occurred between subsequent time points (p < or = 0.0018). In the instrumented animals, the mean plasma troponin I level increased from 1.4 +/- 1.6 microg/liter to 2.8 +/- 2.3 microg/liter (p < 0.001). However, troponin I was not detected before or after induction of brain death in the plasma of either non-instrumented animal (p = 0.001). CONCLUSIONS: The sympathetic storm produced transient contractile dysfunction, consistent with ischemic injury. However, troponin I release reflected surgical instrumentation and not brain death.

Animals↗

Recent advances in cataract surgery.

Cataract surgery has undergone profound changes in the past ten to twenty years. Not only are these changes evident in the technique and methods of extraction, but it has become critical for the well-versed ophthalmic surgeon to be concerned with the optical correction of aphakia. New instruments, highly refined microscopes, and better diagnostic techniques have all contributed to significant improvement in the result of the procedure. Sophisticated surgical instruments are now available for highly trained surgeons. Intraocular lens implantation (pseudophakia) has introduced one of the greatest controversies in ophthalmic surgery. The advantages and disadvantages of this process are set forth.

Cataract Extraction↗

Trends and perspectives in minimally invasive surgery in otorhinolaryngology-head and neck surgery.

The roots of minimally invasive surgery (MIS) in otolaryngology-head and neck surgery (ORL-HNS) can be traced to the 1950s. Today, endonasal sinus surgery and endolaryngeal surgery already fulfill the principles of MIS. To widen its spectrum of indications, however, MIS must be able to offer three advantages that conventional macrosurgery and microsurgery already have: free maneuverability for the instrument, sensory feedback, and three-dimensional imaging. Every anatomical region (e.g., paranasal sinuses, upper aerodigestive tract, cerebellopontine angle) requires specific surgical instrumentation. Here, the authors present recently developed steerable instruments that allow two additional degrees of freedom not attainable with conventional instruments. These instruments may permit access to problem zones (e.g., laterally extending frontal and ethmoidal sinus recesses) in the near future. For better control of the instrument and the operative procedure, tactile feedback can be achieved with appropriate microsensor systems. Three-dimensional vision can be realized by three-dimensional video-endoscopes and sequential image processing.

Endoscopes↗

Medical abortion: overview and management.

Medical abortion regimens are safe, effective, and offer a new range of choices for patients and providers. In September 2000, the US Food and Drug Administration (FDA) approved a regimen of mifepristone and misoprostol, which effects abortion by luteolysis, uterine contractions, and expulsion of the products of conception without surgical instrumentation. The regimen requires that a provider be capable of diagnosing ectopic gestations and be able to make arrangements for a surgical abortion in the case of failure or medical emergencies. With a medical abortion, the pregnancy is passed spontaneously, and there may not be tissue obtained for confirmation. Physicians must be aware of their state requirements with regard to expulsed tissue examination. Completion of the procedure can be established by ultrasound or by measurement of serum levels of human chorionic gonadotropin (hCG). The FDA-approved protocol allows for use up to 49 days after the first day of the last menstrual period (LMP) and consists of mifepristone 600 mg orally on day 1, misoprostol 400 mcg orally on day 3, and a follow-up appointment on days 12-20. Half of all patients pass their pregnancy in the first few hours after the second visit. It is important to be able to determine the difference between expected bleeding, 14 days on average, and the complication of hemorrhage, as 2% to 10% of patients require a surgical abortion. Continuing viable pregnancies are rare. Several other regimens can safely expand options and reduce expense, including protocols using methotrexate. Medication indications and contraindications, management strategies for patients undergoing treatment with these regimens, and safety issues are reviewed.

Abortifacient Agents, Nonsteroidal↗

Intraoperative ultrasound imaging in lumbar disc herniation surgery.

The diagnosis of lumbar disc herniation has improved with metrizamide rhizography and CT. Also, visualization of the operative site has been enhanced with use of the operating microscope. However, evaluation of the completeness of herniated disc removal can be difficult, especially in the case of medially located lesions. Also, intradural extension of the herniation can be impossible to rule out in some cases without intradural exploration. Intraoperative ultrasound imaging is safe, rapid and readily available in most hospitals. Its application to real-time imaging control of 10 selected cases of herniated lumbar disc showed that the herniated material could be visualized in relation to the interspace and dural sac in all cases. The effect of removal of the herniation on nerve root compression could also be evaluated. Especially in cases involving extension of the herniation to the medial region under the dura, or into the intradural space, the removal of herniated material could be adequately confirmed without the need for further manipulation with surgical instruments. With appropriate transducer design and frequency, the method can be applied to microsurgical technique to rule out sequestration outside of the surgical exposure.

Adult↗