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Results for “SHEEP DISEASES”

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At least 919 records · Page 51Linked to original sources
PubMed1976

[Dermatophyte infections in animals (author's transl)].

Dermatophytes are more or less species-specific in animals. The diagnosis may be based on the microscopic specimen and is verified by cultural studies. This is subject to the restriction that fungus spores are only microscopically and culturally detectable during a particular period in which clinical symptoms are present. When the animal has had a primary infection, immunity will occur. This immunity is believed to play a role as early as spontaneous recovery from the primary infection. The stage of the disease should be taken into account in treating dermatophyte infections. The economic significance and risk of infection in human subjects are briefly discussed.

Animals↗
PubMed1977

Transmission of a mucosal disease virus infection between sheep.

The transmission of mucosal disease virus (MDV) from infected ewes and their lambs to susceptible sheep was investigated. MDV was recovered from the amniotic fluid of an infected pregnant ewe and from the blood, nasal swabs and urine of hairy lambs. MDV infection was transmitted either at lambing, from infective foetal fluids or lambs, or later as a result of contact with a surviving with a hairy lamb and either aborted or gave birth to an infected hairy lamb. Adult sheep and 12-months-old sheep were less readily infected than were newborn lambs. Pregnant ewes were infected by contact with a hairy lamb and either aborted or gave birth to an infected hairy lamb. A method to minimise spread of the infection in the field is suggested.

Animals↗
PubMed2000

Seroprevalence of Border Disease in Danish sheep and goat herds.

A study was conducted in 1994-96 with the aim of assessing the serological prevalence of Border Disease (BD) among sheep and goats in Denmark and to investigate possible relations to herd factors. From each of 1000 herds, 2 blood samples were obtained from animals older than 1 year. The examination for antibodies was performed using a blocking ELISA detecting antibodies to pestivirus. Data from 815 herds were analysed statistically by the maximum likelihood method in a multinomial model. The estimated herd prevalence was 0.083 and the estimated individual prevalence within the positive herds was 0.50. There was no difference between the prevalence in sheep and goat herds. Records for well over half of the herds could be combined with data from the Danish Central Husbandry Register. No association between occurrence of BD and herd size was found. Cattle were registered as contemporarily present on 135 out of 521 herds which was shown to be strongly associated to BD. The estimated herd prevalences of BD among farms with and without contemporary cattle were 0.24 and 0.042, respectively.

Animals↗
PubMed1991

A monoclonal antibody capture ELISA to detect antibody to border disease virus in sheep serum.

An enzyme-linked immunosorbent assay (ELISA) has been developed to detect antibody to border disease virus (BDV) in sheep serum. A monoclonal antibody bound to 96-well microplates was used to capture antigen from detergent-solubilised BDV-infected cells. Single dilutions of test sera were then added to wells containing bound BDV antigen and control wells containing uninfected cell lysates. Specific antibody to BDV was detected by an anti-ovine IgG antiserum conjugated with horseradish peroxidase and the results expressed as ELISA units with reference to a standard curve. Sequential sera from 16 experimentally infected sheep and single sera from 103 sheep involved in a field outbreak were tested in the ELISA and for neutralising antibody. There was good qualitative correlation between the two tests.

Animals↗
PubMed1997

The detection of antibodies against foot-and-mouth disease virus in sheep milk.

The liquid-phase blocking ELISA (LPBE) and a specific isotype assay (SIA) modified for caprine/ovine IgG1 and IgG2 were used to detect antibodies against foot-and-mouth disease virus isolate O(1) Manisa in sheep milk samples. The majority of samples from animals vaccinated 14-23 weeks previously were indistinguishable from naive sheep when tested in the LPBE but 97% were positive using the SIA. All milk samples taken at 7 days after parturition from immunised animals were positive by LPBE. Thereafter, this proportion declined, although occasional reactors were detected at every stage up to 83 days. However, when mean titres were calculated for every sampling point after lambing, results were only positive for the first 18 days in this test. By contrast, the SIA was able to detect almost all (i.e. 97%) the vaccinated animals up to 83 days post parturition. Milk samples from convalescent animals all gave positive results in the assays. Sicilo-Sarde sheep gave higher titres on average than the Commisane breed at comparable stages after lambing. Both tests could be used for surveillance purposes following an outbreak of FMD to identify flocks of sheep which had been infected, but the SIA would be required to show the presence of vaccinated animals unless they were sampled soon after parturition.

Animals↗
PubMed1990

Grazing management strategies for the control of parasitic diseases in intensive sheep production systems.

The effect of forward (F) and lateral (L) creep grazing, as two possible management alternatives of intensive production systems, on the gastro-intestinal nematode epidemiology of ewes and lambs was studied. Two groups of Romanov x Rasa Aragonesa ewes rearing twins and maintained on an autumn-contaminated pasture at a mean stocking density of 35 ewes ha-1, were used. Measurements were made of the population of infective larvae on the pasture, level of serum pepsinogen, worm eggs in faeces of ewes and lambs, and lambs' growth rate. In addition, post-mortem worm counts from 'indicator' lambs were used to establish the level of infection at each rotational grazing cycle. Two different waves of nematode infection were identified. In both treatments, the over-wintering larvae were responsible for the first outbreak of parasitism which was particularly important for lambs on Treatment F. The second wave of infection apparently came up with several overlapped L3 generations and had different effects on the animals of each group. While early pasture contamination was suffered by the lambs of Treatment F, lambs on Treatment L were not seriously affected until the end of the third grazing cycle (end of May). The different grazing behaviour of lambs in both treatments appeared to be related to the outbreak of parasitism in lambs. The general pattern of liveweight gains was similar for both groups of animals. However, during the first 90 days on pasture lamb growth rate under Treatment L (193 g day-1) was significantly higher than that under Treatment F (164 g day-1). The serum pepsinogen values, worm burdens and liveweight gains indicate that under intensive systems where lateral creep grazing is allowed for lambs, the level of parasite infection is maintained within acceptable limits for the first 90 days on pasture with lambs' growth rate close to their potential. However, the parasitic consequences of grazing under a forward creeping system indicate that anthelmintic drenchings should be used at lambing and at 3-week intervals thereafter during the first 42 days on pasture, after which the risk of contamination from the over-wintering population is over.

Animal Husbandry↗
PubMed1987

Chronic allergic airway disease in the sheep model: functional and lung-lavage features.

We developed an animal model of chronic allergic airway disease by repeatedly exposing nine sheep to tracheal instillation of ascaris antigen until stable increase in lung resistance at three times control in six reactive sheep (group C) was obtained. They were then compared to the three nonreactive sheep (group B) and a control group of eight sheep exposed to saline only (group A) in terms of pulmonary function tests and bronchoalveolar lavage (BAL) analyses. Lung resistance was 1.5 +/- 0.3 cm H2O/L/sec in group A, 1.8 +/- 0.3 in group B, and 5.9 +/- 1.3 in group C. Trapping volume (functional residual capacity by plethysmography and by helium rebreathing technique) was 0 +/- 0.1 L in group A, 0.05 +/- 0.1 in group B, and 0.51 +/- 0.17 in group C. Upstream resistance at peak flow did not differ between any two groups, but upstream resistance near residual volume was 1.8 +/- 0.3 cm H2O/L/sec in A, 6.2 +/- 1.0 in B, and 28 +/- 6 in C. In BAL, total cells were 25 +/- 5 X 10(4)/ml in A, 35 +/- 8 in B, and 31 +/- 6 in C. Macrophages in BAL were 16 +/- 2 in A, 27 +/- 9 in B, and 24 +/- 4 in C. Neutrophils were 0.5 +/- 0.2 in A, 3.4 +/- 2.5 in B, 2.8 +/- 1.5 in C. Eosinophils were 0.1 +/- 0.1 in A, 0.5 +/- 0.2 in B, and 0.9 +/- 0.3 in C (p less than 0.05 group C versus group A). Total proteins, albumin, alkaline phosphatase, and fibronectin did not differ between groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Airway Resistance↗