Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “SCALP”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 919 records · Page 51Linked to original sources
PubMed2006

Scalp reconstruction.

Scalp reconstruction after oncologic resection can be challenging. Wide surgical resections, in combination with co-morbid conditions such as infected alloplastic material, cerebrospinal fluid (CSF) leak, or devascularized bone after craniotomy necessitate healthy, vascularized tissues for reconstruction. Although primary closure is feasible in some cases, the mainstay of treatment involves local tissue rearrangement with or without split thickness skin grafting. In addition, free tissue transfer is an important adjunct to therapy in patients with poor local tissues. Careful analysis of the defect and local tissues can help tailor the method of reconstruction and result in satisfactory closure in a majority of patients. Current techniques used for scalp reconstruction after surgical ablation are the subject of this review.

Craniotomy↗
PubMed1979

Malignant melanoma of the scalp.

Malignant melanoma of the scalp has a significantly worse prognosis than cutaneous melanoma arising in other head and neck sites. In this series, 125 patients were treated for Stage I invasive melanoma of the scalp and followed 3 to 19 years. Survival rates for these patients were calculated on the basis of several factors. Survival after treatment was not affected by the age and sex of the patient, size and site of the primary, or treatment of the primary lesion, although local failure was higher among those treated by primary excision and closure. Patients undergoing elective neck dissection with histologically negative nodes had significantly better survival rates than those with histologically positive nodes or patients in whom a neck dissection was not performed.

Adolescent↗
PubMed2002

Aesthetic and functional advantages of the anterolateral thigh flap in reconstruction of tumor-related scalp defects.

Eleven patients underwent free-flap reconstruction of tumor-related defects of the scalp, forehead, and temporal region. Flap selection aimed at achieving acceptable functional and aesthetic results combined with negligible donor-site morbidity. Ten males and one female, aged 61.3 +/- 14.3 years, were included in this study. Eight patients presented with tumor recurrences after previous surgery, irradiation, and/or chemotherapy. The average extension of defects was 169.5 (range, 30-600) qcm. Free flaps employed for reconstruction included antero-lateral thigh flaps (8), suprafascial radial forearm flap (1), lateral arm flap (1), latissimus dorsi muscle flap (1), and myocutaneous vertical rectus abdominis flap (1). Other procedures included nerve grafts to the facial nerve (2), ectropion correction (2), and fascia lata slings for static procedure in facial palsy (2). There was no pedicle revision and no flap failure. Donor-site morbidity was negligible. Hospitalization averaged 9.2 +/- 1.7 days. The anterolateral thigh perforator flap offers excellent coverage of tumor-related defects of the scalp, which require a thin flap for adequate contouring. The customized harvested myocutaneous anterolateral thigh flap is regarded as an elegant option for covering defects which consist of both deep and superficial areas. Fascia lata and nerve grafts are available at the same donor site. This easily allows additional procedures for cosmetic and functional improvement that are of high benefit for patients.

Adult↗
PubMed2006

One-stage reconstruction of large scalp defects: anterolateral thigh flap.

Seven patients with large scalp and calvarial defects underwent reconstruction with free tissue transfer. Patients fell into two groups according to etiology: tumoral (five) or traumatic (two). A single type of free flap was used in each patient, i.e., the anterolateral thigh flap. Duraplasties with the flaps' vascularized fasciae were performed in two patients with minor calvarial defects, and nonvascularized fasciae were used in another two, with a cranioplasty using methylmethacrylate. One postoperative death and one venous congestion necessitating exploration were observed. The explored anastomosis revealed occlusion of the venous anastomosis; drainage with a venous graft into the neck veins was performed. Minor tissue loss with secondary healing was observed in the flap. Extensive scalp defects often necessitate challenging reconstructive procedures. Single-stage reconstruction with good qualified tissue is possible with a free tissue transfer. The anterolateral thigh flap provides a large amount of tissue with decreased donor-site morbidity and good cosmetic results.

Adult↗
PubMed1998

The present mercury contents of scalp hair and clinical symptoms in inhabitants of the Minamata area.

A total of 191 fishermen and their family (32-82 years) living in some mercury-polluted areas along the Shiranui Sea volunteered for the present study. They made a living by fishery and had formerly eaten the methyl mercury-contaminated fish and shellfish caught there. The questionnaire on subjective symptoms, fish eating habits, and past living history was conducted on the subjects. In addition, they were clinically examined in detail by several neurologists and scalp hair was collected. With six exceptions, all the 185 subjects showed a normal total mercury level in hair (<10 ppm). The ratio of methyl mercury to total mercury was 79-94% on the average for each group examined, suggesting indirect contamination (perhaps through the food chain). Despite their low mercury level in scalp hair, however, the subjects showed various neurological symptoms, particularly, sensory disturbance (such as the glove and stocking type), at a very high rate. Thus, it seems fair to state that, in addition to officially recognized Minamata disease patients, there still exist many people with atypical, slight Minamata disease on the coast of the Shiranui Sea. The current hair mercury level is not necessarily useful as a criterion for diagnosing chronic Minamata disease because of the long lapse of time.

Adult↗
PubMed1997

Endometrial adenocarcinoma metastatic to the scalp: case report and literature review.

A rare case of scalp metastasis from endometrial adenocarcinoma, demonstrating the poor prognosis for these patients, is reported. A 56-year-old woman with FIGO Stage IC, Grade 1 endometrial adenocarcinoma presented 15 months after initial surgery and radiation therapy with a scalp metastasis. Metastatic evaluation revealed widespread extrapelvic disease. She did not respond to chemotherapy and died 3 months after recurrence. Her course typifies that of patients with other cutaneous metastases as described in the literature: disease noted elsewhere at the time of recurrence, poor response to therapy, and death within 6 months.

Adenocarcinoma↗
PubMed2002

Scalp metastasis in carcinoma of the uterine cervix--a rare entity.

BACKGROUND: Distant metastasis in carcinoma of uterine cervix is a rare manifestation and bone metastasis is uncommon. CASE: A 60-year-old woman treated by radical radiotherapy for moderately differentiated cervical carcinoma FIGO stage IIIB presented 4 months later with swelling over right side of the scalp. Fine needle aspiration cytology from swelling showed poorly differentiated metastatic carcinoma. X-ray of the skull was suggestive of osteolytic metastasis of calvaria. CONCLUSION: Bone metastasis in cervical carcinoma is a late manifestation of advanced malignancy and heralds poor prognosis. Scalp metastasis is a very rarely reported phenomenon.

Bone Neoplasms↗
PubMed1985

Horizontal scalp distribution of steady-state pattern visual evoked cortical potentials in response to quadrant field stimulation.

Scalp profiles of steady-state pattern visual evoked cortical potentials (VECPs) along the horizontal line at Pz (for upper field stimuli) and Oz (for lower field stimuli) were studied in 12 normal subjects by simultaneous five channel recordings from electrode positions 3 cm and 6 cm laterally on either side of, and at, Oz or Pz. Each electrode was referred to Fz or to the right earlobe. The amplitude and phase of the averaged VECPs (n = 20) were calculated by means of Fast Fourier Transform. With smaller check size the amplitude data verified that the scalp profile of the lower visual field peaked at the hemisphere contralateral to the quadrant stimulated. With larger check size the peak shifted to the ipsilateral hemisphere. With upper field quadrant stimulation, position of the reference electrode at Fz was found to be unsuitable since the VECP amplitude at the level of Pz was greatly reduced. Phase and apparent latency also varied with the field stimulated as well as with the position of electrodes.

Cerebral Cortex↗
PubMed1987

Scalp distribution of visual evoked potentials to foveal pattern and luminance stimuli.

Scalp potentials elicited by pattern reversal, pattern onset, and flash stimulation have been studied in normal subjects by means of a 16-channel brain mapping system. In two groups of experiments the topography of the major positive component in each response was compared with 4 degrees full- and lateral half-field stimuli and, for more detailed exploration of the pattern components by M-scaled stimuli selected to activate 1 cm2-patches of striate cortex and associated extrastriate re-projections. The 4 degrees stimuli were found to elicit scalp distributions for the pattern reversal P100 and the pattern onset C1 consistent with striate and extrastriate visual cortical origins respectively. Data on the flash P2 component suggest that stimulation was not localized accurately; this may have been due to lateral spread of neural activity in the retina. Predictably, the M-scaled stimuli showed extensive inter- and intraindividual variations depending on stimulus type and location relative to fixation. The manner in which, in some subjects, the region of maximal activity on the map appears to migrate with change of stimulus position possibly reflects local retinotopic order in visual evoked potential generator areas. However, data are neither extensive nor detailed enough to be conclusive.

Adult↗
PubMed1995

Scalp topography and analysis of intracranial sources of face-evoked potentials.

Several reports have described that a positive vertex peak of an evoked potential varied in amplitude and latency specifically when images of faces were the eliciting stimulus. The scalp topography and the possible underlying dipole sources of this peak are the subject of this report. We presented black-and-white photographs of human faces, flowers and leaves to 16 healthy subjects and recorded the evoked brain potentials from 31 scalp electrodes. We found the previously described higher amplitude of the positive vertex peak when faces were the crucial stimulus, but the latency of this peak was the same (180 ms) for all three categories of stimulus. At the posterior temporal electrodes, the face waveforms showed a negative peak at 175 ms, which was only rudimentary in the waveforms elicited by the other stimuli. Since in most previous reports a mastoid reference was used, it is most likely that the previously described latency shift of the positive vertex peak associated with face stimuli was due to the interaction with this posterior temporal peak. The dipole analysis of the possible generators of the recorded potentials suggested the sequential activation of occipital, lateral temporal and mesio-temporal brain structures during the perception of a human face.

Adult↗
PubMed1992

The vertex-positive scalp potential evoked by faces and by objects.

The influence of stimulus form on the scalp-recorded "vertex positive peak" (VPP) evoked by images of faces (Jeffreys 1989a) was studied in seven subjects. In separate experiments, we recorded the responses to 2D images of: (1) many different depictions of human faces; (2) the heads of several different species; (3) many familiar non-face objects; and (4) stimuli where the configuration of objects were modified to produce an "illusory" or "non-contextual" subjective impression of a face. The results showed that every facial representation, including the "illusory" stimuli, and most of the non-face objects, evoked a VPP of corresponding form and scalp distribution. The object-evoked VPPs, however, were always smaller and usually later than those evoked by the faces. VPPs of longer latency but often comparable amplitude were also recorded for impoverished compared to well-defined facial representations; and for most non-human compared to human faces. Very consistent responses were recorded to repeated presentations of the same stimulus for the same subject, but there was considerable variation in latency as well as amplitude (but not form) of the VPP evoked under identical experimental conditions for different subjects. These response properties of the VPP, suggest that its underlying physiological generators are sensitive to basic configural properties of the visual stimulus; and also the face- and object-related information are processed in the same brain area(s), although not necessarily by the same physiological mechanisms.

Adult↗
PubMed1979

Congenital scalp defects associated with postaxial polydactyly.

A family is reported, several members of which had congenital scalp defects and postaxial polydactyly type A, with wide variability of expression. The hypothesis is formulated that this association is not fortuitous, but is a distinct malformation complex in which congenital scalp defects are associated with distinct malformation of the limbs.

Adult↗
PubMed1994

Merkel cell distribution in human hair follicles of the fetal and adult scalp.

The distribution of Merkel cells in fetal and adult terminal hair follicles of human scalp was studied immunohistochemically using cytokeratin (CK) 20 as a specific Merkel cell marker. In hair follicles of adult scalp, abundant Merkel cells were found enriched in two belt-like clusters, one in the deep infundibulum and one in the isthmus region. No Merkel cells were found in the deep follicular portions including the bulb, or in the dermis. In early fetal hair follicles (bulbous peg stage), Merkel cells were only detected in the basal layer of the developing infundibulum but not in deeper follicular areas. In later stages, Merkel cells were also present in the isthmus and bulge. No Merkel cells were seen in the dermis around developing hair follicles. Nerve growth factor receptor was not only present in nerves but was found to be widely distributed within fetal skin. In adult skin, this receptor was localized to the basal cell layers of the outer root sheath of the bulb and the suprabulbar area, but was not detectable in the areas containing Merkel cells. The present study localizing Merkel cells within the permanent hair follicle structures close to their possible stem cells suggests that they have paracrine functions.

Adult↗
PubMed1976

Scalp veins as collateral pathway with parasagittal meningiomas occluding the superior sagittal sinus.

In 3 cases with occlusion of the superior sagittal sinus (SSS) with parasagittal meningiomas, carotid angiography demonstrated scalp veins as an important collateral venous pathway. The authors believe that occlusion of the SSS is best seen in half axial oblique carotid phlebograms under contralateral carotid compression. Direct sinography is time consuming and troublesome. In the presence of scalp veins as important collaterals, strategic consideration for surgical treatment is discussed.

Adult↗
PubMed1991

Expression of tenascin in perifollicular connective tissue: comparison of normal scalp and alopecia areata.

Tenascin, a recently discovered extracellular matrix protein, was demonstrated in perifollicular connective tissue of normal human scalp using immunohistochemistry. Its localization was different from other well-known extracellular matrix components, like fibronectin, laminin and heparan sulphate proteoglycan. A comparison between alopecia areata and normal scalps did not reveal major qualitative differences, except for an increased expression near heavily infiltrated follicles.

Alopecia Areata↗
PubMed1995

Scanning electron microscopic observations of extracted terminal hair follicles of the adult human scalp and eyebrow with special references to the bulge area.

Scanning electron microscopic studies of human terminal hair follicles of the scalp and eyebrow have previously been limited to the hair shaft. In this study we investigated EDTA-treated extracted whole hair follicles in which most of the basal cell surface of the outer root sheath was well preserved. In the bulge area of scalp follicles there were many knob-like or villous projections. These were located in some specimens on one side of the follicle, while in others they were located around the entire circumference of the follicle. These projections were thought to represent the anchoring points of the branched follicular end of the arrector muscles. Ring-like elevations with groove-like depressions above and below were also observed surrounding the entire follicle. These were thought to represent the track of circumfollicular arrector muscles which depressed the outer root sheath when they repeatedly contracted. Most anagen eyebrow follicles showed morphological variations in the bulge area such as lattice-window-like structures and undulation patterns. In telogen follicles, the bulge became indistinguishable from the clubbed end. The lower end of these telogen follicles showed irregularly shaped bulge areas, but did not show lattice-window-like structures or undulation patterns as observed in anagen follicles. Interestingly, a hole was found in some bulge areas of both anagen and telogen follicles. Serial vertical sections of follicles revealed invaginated areas, which seemed to correspond to the openings seen in whole mounts. In vertical sections of eyebrow follicles some keratinocytes of the outer root sheaths of the bulge area were seen to be melanized to various extents. This phenomen was independent of hair cycle phase.

Adult↗