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At least 919 records · Page 51Linked to original sources
PubMed1982

[Salmonella dublin enteric fever in two compromised hosts].

Salmonella (S) dublin is a rare cause of human enteric fever. We studied 2 compromised hosts, one of them being treated for lymphocytic leukemia and the other for chronic lymphocytic leukemia. Both had recurrent enteric fever caused by S. dublin. Both strains were resistant to chloramphenicol and to ampicillin and the patients were treated by trimethoprim-sulfamethoxazole to which the organism was sensitive. Investigations failed to discover an extraintestinal localisation and stool cultures remained negative after antibiotic treatment. One patient had a relapse of enteric fever at every relapse of his leukemia; the second patient after his second episode of enteric fever was treated prophylactically during 3 months. When he stopped antibiotic prophylaxis a fatal S. dublin septicemia occurred. We suggest that compromised hosts with S. dublin infection be treated prophylactically to prevent relapse.

Adult↗
PubMed1999

Q fever.

Q fever is a zoonosis with a worldwide distribution with the exception of New Zealand. The disease is caused by Coxiella burnetii, a strictly intracellular, gram-negative bacterium. Many species of mammals, birds, and ticks are reservoirs of C. burnetii in nature. C. burnetii infection is most often latent in animals, with persistent shedding of bacteria into the environment. However, in females intermittent high-level shedding occurs at the time of parturition, with millions of bacteria being released per gram of placenta. Humans are usually infected by contaminated aerosols from domestic animals, particularly after contact with parturient females and their birth products. Although often asymptomatic, Q fever may manifest in humans as an acute disease (mainly as a self-limited febrile illness, pneumonia, or hepatitis) or as a chronic disease (mainly endocarditis), especially in patients with previous valvulopathy and to a lesser extent in immunocompromised hosts and in pregnant women. Specific diagnosis of Q fever remains based upon serology. Immunoglobulin M (IgM) and IgG antiphase II antibodies are detected 2 to 3 weeks after infection with C. burnetii, whereas the presence of IgG antiphase I C. burnetii antibodies at titers of >/=1:800 by microimmunofluorescence is indicative of chronic Q fever. The tetracyclines are still considered the mainstay of antibiotic therapy of acute Q fever, whereas antibiotic combinations administered over prolonged periods are necessary to prevent relapses in Q fever endocarditis patients. Although the protective role of Q fever vaccination with whole-cell extracts has been established, the population which should be primarily vaccinated remains to be clearly identified. Vaccination should probably be considered in the population at high risk for Q fever endocarditis.

Animals↗
PubMed1984

Adenomectomy in a patient on regular dialysis treatment.

A 55-year-old patient presented with terminal renal insufficiency caused by lower urinary tract obstruction due to prostatic adenoma. The case history of the patient on regular dialysis treatment was complicated by recurrent, therapy-resistant urinary tract infections accompanied by septic fever outbreaks and anemic relapses. Following suprapubic transvesical adenomectomy, no fever episodes, negative urine cultures and improvement in the anemic condition were all noted. Due to the fact that the upper age limit for acceptance into a hemodialysis program and possible kidney transplantation has been raised, it is important to note that an increasing number of men with prostatic adenomas may be encountered in these collectives. Dialysis patients require successful treatment of urinary tract obstructions prior to transplantation. Immunosuppressive therapy which follows transplantation increases the risk of infection which can endanger the graft and the patient's life.

Humans↗
PubMed2001

[Ultrastructural analysis as a method of studying bacteremia in infectious diseases].

To study bacteremic processes with transmission electron microscopy, blood groups were examined in the representative groups of patients with typhoid fever, generalized forms of yersinosis, pseudotuberculosis, Flexner's shigelosis, and Sonne's shigelosis at different stages of acute cyclic diseases and in those with chronic Salmonella typhi carriage. Bacteremia of typical unaltered causative organisms is shown to occur only in the feverish period of disease. The morphofunctional organization of a causative agent in this period is similar to that of museum bacterial strains, except that the bacteria circulating in the blood of patients have vesicles that are morphologically equivalent to endotoxin. In reconvalescence, the blood circulation of causative organisms continues, but they appear as morphologically changed bacteria and as forms with their defective cellular wall (spheroplasts and protoplasts). Transmission electron microscopy reveals bacteria of other systematic groups in the patients' blood when acute Salmonella typhi carriage is under way or when there are typhoid fever-induced complications or relapses, clinically unfavorable running of typhoid fever, generalized forms of yersinosis and pseudotuberculosis are present. In chronic Salmonella typhi carriage, the patients' blood displays altered bacterial cells and forms with defective cell wall, among them there are prominent morphological types that are structurally identical to uncultured bacterial forms. The study of blood samples from infected patients has show that transmission lectron microscopy can be used to detect blood circulating microorganisms at different stages of acute and chronic patterns of an infectious process.

Bacteria↗
PubMed1983

[Prostatic adenomectomy in dialysis patients].

A case of a 55-year old patient is presented with terminal renal insufficiency and a massive prostatic adenoma causing urinary tract obstruction. The case history of the patient on mandatory dialysis was complicated by recurrent, therapy resistant urinary tract infections accompanied by septic fever outbreaks and anemic relapses. Following suprapubic transvesical adenomectomy, no fever episodes, negative urine cultures and improvement in the anemic condition were all noted. Due to the fact that the upper age limit for acceptance into a hemodialysis program and possible kidney transplantation has been raised, it is important to note that patients with prostatic adenomas may be frequently encountered. Dialysis patients require successful treatment of urinary tract obstructions prior to transplantation. Immunosuppressive therapy which follows transplantation increases risk of infection which can endanger the graft and the patient's life.

Adenoma↗
PubMedDate not supplied

Periodic (Pel-Ebstein) fever of lymphomas.

During lymphomatous diseases, bouts of intermittent or relapsing Pel-Ebstein fever occasionally repeat in remarkably regular tempo resembling the episodes of benign periodic fever. Febrile episodes alone, especially during acute lymphomatous disease, occasionally precede overt evidence of underlying disease for months. In that event, diagnosis and treatment of lymphomas are delayed. Regular febrile bouts are either uniquely characteristic of lymphomas or represent the imposition of periodic fever. Apprehension of malignant disease during benign periodic fever may induce intensive investigation. Malignant disease has not ensued in reported cases of periodic fever.

Adult↗