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[Neural mechanisms of group I fibers of neck muscles (author's transl)].

Afferent projection of upper cervical dorsal roots C2 and C3 upon spinal cord and brain stem was investigated on cats using both histological and electrophysiological methods. 1. Degenerated terminals, stained by Fink-Heimer's methods, were found in Rexed's laminae III and IV, intermediate nucleus and ventral horn of the spinal cord and nucleus cuneatus and spinal trigeminal nucleus. 2. Monosynaptic reflex responses were obtained from motor nerves innervating dorsal neck muscles by stimulating the dorsal roots in some decerebrated cats. However, this reflex responses could be unable to elicite in the spinal preparation. 3. The neurons responding exclusively to the ventral rami located in cranial parts of the nucleus and those responding to dorsal rami located in the caudal region. Neurons responding to both rami were also found.

Animals↗

[Changes in motor neuron excitability during the organization of voluntary movements].

In healthy subjects, H-testing revealed no specific changes of motoneuron excitability during the latency period of voluntary motor activity of movement agonist whereas the H-reflex was augmented prior to movements triggered by a sound signal, the augmentation being the result of the sound activating effect mainly (startle--response). Sharp augmentation of the H-reflex occurs at the beginning of agonist voluntary activation due to interaction between the reflex and the voluntary muscular activities (interaction of peripheral and supraspinal effects on the motoneurons).

Cues↗

[Primary localization of the pathologic process in amyotrophic lateral sclerosis].

The clinico-electromyographical study was conducted in 120 patients with motor disturbances in amyotrophical lateral sclerosis. Comparing the clinical and electromyographical data in different variants of this disease the authors make a conclusion on the simultaneous damage of peripheral and central mononeurons from the very onset of the disease. Along with this the latter is damaged not only primarily, but secondarily as a result of trans-synaptic degerneration due to pathology of the segmental-nucleus motor cells.

Adolescent↗

[Reflex circuits of the spinal cord in man. Control during movement and their functional role (1)].

For many years descending and reflex effects were treated as separate entities, spinal reflex pathways being considered as more or less vestigial. In fact convergence of descending tracts and primary afferents onto common spinal interneurones interposed in spinal reflex pathways is the rule. Such convergences suggest that these spinal interneuronal systems play an important integrative role in motor control: transmission of afferent signals resulting from movement can be modified by the descending command and, in turn, impulses in primary afferents can modify the descending command and contribute to the final shaping of movement. How these convergences are used in motor control, however, cannot be known from acute animal experiments. This would require experiments performed during natural movement. Now that it is possible to investigate spinal pathways in man, such experiments can be undertaken. Several spinal pathways can be studied in man with reasonably reliable methods: Ia excitatory pathways from muscle spindle primary endings, the pathway of reciprocal la inhibition, the circuitry of the recurrent inhibition through Renshaw cells and the pathways fed by Ib fibres from Golgi tendon organs.

Central Nervous System↗