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At least 919 records · Page 51Linked to original sources
PubMed2000

Epithelioid/granular soft tissue lesions: correlation of cytopathology and histopathology.

Polygonal shaped epithelioid cells are not an infrequent component of soft tissue mass lesions. Such cells exist in association with other cellular shapes (eg, spindle, pleomorphic, stellate, etc) in both tumors and tumor-like conditions. Conversely, only a handful of soft tissue lesions contain either a pure or predominant epithelioid cell population. The cytoplasmic texture of such cells may be finely or coarsely granular, striated, vacuolated, or have combinations of these features. Since a relatively small body of literature on fine needle aspiration cytopathology of soft tissue exists (as compared to other body sites), and there is a lack of using the fine needle aspiration technique for soft tissue tumors in most medical centers, most pathologists are precluded from having the opportunity to correlate the cytopathology and histopathology of epithelioid soft tissue lesions. The aim of this review is to highlight the morphologic features (as seen in both tissue sections and aspiration smears) of this group of soft tissue lesions in order to assist the reader in their recognition, discuss the cytomorphologic and histomorphologic similarities and differences among these lesions, and delineate the limitations in their recognition particularly with the cytologic method.

Biopsy, Needle↗
PubMed2005

[Heart tumors: magnetic resonance imaging and multislice spiral CT].

Transthoracic echocardiography is usually the initial diagnostic test in patients with a suspected cardiac mass. However, this technique is restricted by its small field of views and insufficient acoustic window in some patients. Magnetic resonance imaging (MRI) and, since its introduction, multislice spiral computed tomography allow for detailed delineation of intra and pericardiac tumors, their extent, and their influence on cardiac function. Primary benign and malignant cardiac tumors have several characteristic features in MR imaging. Assessment of such features may narrow down the differential diagnosis or even allow for reliable diagnosis in selected cases. Many such features can also be assessed using MSCT. This article provides an overview of examination protocols of MRI and CT for cases in which a cardiac mass is suspected and describes the appearance of primary and secondary cardiac masses as well as intracavitary thrombi.

Adult↗
PubMedDate not supplied

[Diagnosis and differential diagnosis of heart tumors in infancy and childhood].

The clinical features of 10 children, in whom the diagnosis of a cardiac tumor has been made, are reviewed. There were nonspecific systolic murmurs in 9 patients, depression of the S-T segment in the ECG of 7 children, and premature extrasystoles or supraventricular tachycardia in 4 children. X-ray always showed mild to moderate enlargement of the heart, but an abnormal contour could be detected only in 2 of the patients. While findings of cardiac catheterization were unspecific, the diagnosis could be made angiographically in 8 cases. Invasive studies, however, are now only indicated, if a proper diagnosis cannot be made by means of echocardiography. The diagnosis should be suspected in children with a nonspecific murmur, cardiomegaly and ECG-changes. Usually the diagnosis of a cardiac tumor is an indication for operation.

Cardiac Catheterization↗
PubMed1992

[Rhabdomyolipoma of the right ventricle].

Echocardiography on a 29-year-old woman with exercise-unrelated tightness in the left chest for some months demonstrated an echo-dense space-occupying lesion in the outflow tract of the right ventricle (RV). Nuclear magnetic imaging revealed an ovular, fat-containing tumour, 3 x 2 x 2 cm in size. Because of threatened obstruction of the RV outflow tract removal of the tumour under cardiopulmonary bypass was undertaken. But complete removal was possible only by resecting a 2 x 3 cm area of the anterior wall of the RV, the resulting defect being covered with a Goretex patch. Histological examination identified the tumour as a rhabdomyolipoma. The patient was free of symptoms 1 year postoperatively.

Adult↗
PubMed1974

Cardiac tumors.

Explore the source record for details and available documents.

Arrhythmias, Cardiac↗
PubMed1989

Rhabdomyomatous mesenchymal hamartoma of skin.

A case of a solitary mesenchymal hamartoma occurring on the chin of a newborn infant is presented. The skin nodule exhibited an abnormal arrangement of dermal mesenchymal elements and, in particular, there was prominence of skeletal muscle. This lesion, which appears to be unique, has been termed rhabdomyomatous mesenchymal hamartoma of skin.

Chin↗
PubMed1990

Multiple rhabdomyomatous mesenchymal hamartomas of skin.

A case of multiple rhabdomyomatous mesenchymal hamartomas is presented. The patient is a black male infant, the product of an uncomplicated term gestation and delivery. At birth, there were numerous polyps distributed over the periorbital and periauricular areas bilaterally. Some appeared fingerlike with constrictions below their tips. Others were branched or globular in shape. These projections showed spontaneous and independent movement, particularly during feedings. On histopathologic examination, the polyps were covered by squamous epithelium and contained normal follicular units. Bundles of skeletal muscle were present in the reticular dermis, extending into the subcutis. Regular cross-striations were seen in these muscle fibers. In some specimens, the muscle bundles formed a solid, central core. Skeletal muscle histochemical stains confirmed the presence of both types 1 and 2 muscle fibers. Electron microscopy revealed a normal skeletal muscle banding pattern. This case is the first report of multiple rhabdomyomatous mesenchymal hamartomas of skin. Functional skeletal muscle with spontaneous movement is part of the clinical picture.

Diagnosis, Differential↗