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[Long-term review of homogeneous and consecutive series of 100 "Charnley"-type total hip prostheses].

PURPOSE OF THE STUDY: Long-term studies of total hip replacements often give diverse results because the series studied are not homogeneous. We report the long-term result in a homogeneous, consecutive series of 100 Charnley total hip replacements for idiopathic hip osteoarthritis in patient without previous surgery, by the same operator. MATERIALS: Of 200 patients with 223 Charnley or Charnley-Kerboull total hip prostheses, implanted more than 13 years earlier, 94 patients with 104 implants were alive at the time of the study. Ninety of them (95.7 per cent) with 100 implants were clinically and radiographically examined. Mean follow-up was 14 yr 8 mo and minimum follow-up was over 13 yr 6 mo. METHODS: Hip function was clinically assessed according to Merle d'Aubigné's criteria. Immediate postoperative x-rays and x-rays at 1, 5 and 10 years and at maximum follow-up were examined. For the acetabulum, alignment, radiolucent line, loosening and wear of the socket were analysed. For the femur, the position of the implant, radiolucent line and loosening, changes in the calcar and cortical bone were analysed. RESULTS: Two femoral implants had to be replaced because of implant fracture. The acetabulum became loose in 3 cases and the femur in 2, but did not require revision at the time of examination. Mean acetabular wear was 0.93 mm (0-5 mm). Wear was greater if the subjects were active (p < 0.05) overweight (p < 0.05) and if the acetabulum was vertical (p < 0.05). Changes in calcar, generally lysis, were more frequent when wear was marked (p < 0.001). Thinning of cortical bone was more frequent in women (p < 0.05), sedentary subjects (p < 0.001) and those in poor general condition (p < 0.05) and was less frequently associated with acetabular wear (p < 0.01). DISCUSSION: This study is characterised by its homogeneity: same etiology, same operator, same implants. Functional outcome at a mean of 14 yr 8 mo after surgery was good, as in most series of Charnley's total hip prostheses. Acetabular wear gave most cause for concern. It was linked with the weight and activity of the patients and with socket alignment. This wear led to deterioration of the calcar, due to granulomas and not to stress shielding. In spite of the homogeneity of the series, no factor was found to account for cortical thickening, whereas cortical thinning occurred in light-weight, osteoporotic patients whose prosthesis did not entirely fill the medullary canal. CONCLUSION: Charnley's total hip prostheses are a good method for treatment of idiopathic hip osteoarthritis. Cement does not appear to be a major deterioration factor over time, unlike polyethylene sockets in which wear and its consequences are a matter for concern.

Adult↗

Cost analysis of fabricating implant prostheses.

This prospective study analyzed the time and costs involved in fabricating implant prostheses in private practice and the factors affecting prosthesis design. Esthetic was the most commonly reported factor influencing the decision to use a fixed or removable prosthesis, while cost was infrequently cited. The single-tooth fixed implant required the least time to fabricate and had the lowest clinical fees, while the removable bar/clip prosthesis had the highest fees and demanded the greatest amount of time to fabricate. Single-tooth fixed and individual attachment removable prostheses generated approximately half the hourly income produced by multiple-unit fixed and bar/clip removable implant prostheses, and the individual attachment design had the highest ratio of expenses to income.

Canada↗

Functional loads on freestanding and connected implants in three-unit mandibular prostheses opposing complete dentures: an in vivo study.

In vivo measurements of vertical forces and bending moments during biting and chewing were carried out on 10 three-unit prostheses in the posterior mandibles of five patients. Each patient had two prostheses, one supported by two implants and the other supported by one implant and one tooth. The results demonstrated no major difference in functional load magnitudes related to the support type. The distribution of load between the abutments was influenced more by the prosthesis geometry and implant placement than by the difference in load characteristics of tooth and implant. This conclusion, however, is limited to one implant connected to a tooth, because multiple implants form a considerably stiffer unit than do teeth. An increase in vertical load resulting from cantilever extensions on the prostheses was documented, both at bite fork measurements and during chewing. No substantial lateral bending was registered, probably because the flat occlusal surfaces and the presence of the opposing complete denture reduced lateral forces.

Aged↗

Long-term results of heart valve replacement with bileaflet prostheses.

Bileaflet cardiac prostheses (St. Jude, CarboMedics, Duromedics, Bicarbon, Jyros) have shown a low incidence of complications and good haemodynamic performance. In the last twelve years, 783 bileaflet prostheses were implanted in 690 patients at our Institution. The population of our study comprises 591 bileaflet prostheses (418 CarboMedics, 124 St. Jude, 49 Bicarbon) implanted in the mitral (MVR) (n = 305) or aortic (AVR), (n = 286) position. The follow-up study evaluated 292 male and 295 female patients with age ranging from 13 and 79 years (mean 50.4 +/- 14.7 years). Hospital mortality was 6.6%. Follow-up was 97% complete, with 1822 +/- 33 patient/years and a mean follow-up of 37 months (range 1 to 144 months). Twelve years actuarial freedom from complication according to prosthetic site were calculated as follows (linearized rates in parentheses): late mortality AVR 97.6% +/- 0.6% (2.3%), MVR 96% +/- 0.5% (2.1%); thrombosis AVR 100%, MVR 96% +/- 0.9% (0.8%); embolism AVR 97% +/- 0.5% (1.5%), MVR 96.6% +/- 0.7% (1.8%). Global freedom from anticoagulant-related haemorrhage was 95% +/- 1.2% (2.3%) and 94.5% +/- 0.7% (2.2%) following AVR, 94 +/- 0.6% (2.1%) following MVR. The difference of the haemorrhagic risk for prosthetic site was not significant (p > 0.05). Functional improvement was confirmed by the low postoperative NYHA functional class. According to our results, cumulative experience with bileaflet valves has shown very good long-term results in term of low rate of complication, long-term survival and quality of life.

Actuarial Analysis↗

Ten-year results for Brånemark implants immediately loaded with fixed prostheses at implant placement.

This investigation was initiated to develop a method to provide patients with a fixed provisional prosthesis placed at the time of implant placement. Sixty-three standard 3.75-mm Nobel Biocare implants of varying lengths were placed into mandibular sites in 10 patients and followed for up to 10 years. Twenty-eight implants were immediately loaded at implant placement, providing support for fixed provisional prostheses, while 35 adjacent implants were allowed to heal submerged and stress-free. Following a 3-month healing period, the submerged implants were exposed and definitive reconstruction was accomplished. All 10 prostheses supported by 28 implants placed into immediate function at the time of implant placement were successful during the 3-month healing period. Of these 28 implants placed into immediate function, 4 ultimately failed. Of the 35 submerged implants, all are osseointegrated and in function to date. Life-table analysis demonstrates an overall 10-year survival rate of 93.4% for all implants. The 10-year life-table analysis of survival is 84.7% for immediately loaded implants and 100% for submerged implants. Statistical analysis of the submerged versus immediately loaded implants demonstrates failure rates for immediately loaded implants to be significantly higher (P = .022 by the log rank test). These data demonstrate that although mandibular implants can be successfully placed into immediate function in the short term to support fixed provisional prostheses, long-term prognosis is guarded for those implants placed into immediate function distal to the incisor region.

Aged↗

Oral rehabilitation with implant-retained prostheses following ablative surgery and reconstruction with free flaps.

Ablative surgery of the oral tissues may result in significant facial deformity, poor oral function, and psychologic detriment. Immediate surgical reconstruction with vascularized free flaps has become increasingly popular, but the oral rehabilitation of these patients with conventional dental prostheses is usually unsuccessful. The results and clinical experiences of treating a group of 17 patients with ablative surgery, immediate reconstruction with free flaps, and restoration with mandibular implant-retained prostheses are presented after follow-up periods of 6 months to 7 years. Most patients expressed a high degree of satisfaction with their prostheses. General principles and guidelines for the provision of this effective treatment modality are discussed.

Adolescent↗

19 mm sized bileaflet valve prostheses' flow field investigated by bidimensional laser Doppler anemometry (part I: velocity profiles).

The investigation of the flow field downstream of a cardiac valve prosthesis is a well established task. In particular turbulence generation is of interest if damage to blood constituents is to be assessed. Several prosthetic valve flow studies are available in literature but they generally concern large-sized prostheses. The FDA draft guidance requires the study of the maximum Reynolds number conditions for a cardiac valve model to assess the worst case in turbulence by choosing both the minimum valve diameter and a high cardiac output value as protocol set up. Within the framework of a national research project regarding the characterization of cardiovascular endoprostheses, the Laboratory of Biomedical Engineering is currently conducting an in-depth study of turbulence generated downstream of bileaflet cardiac valves. Four models of 19 mm sized bileaflet valve prostheses, namely St Jude Medical HP Edwards Tekna, Sorin Bicarbon, and CarboMedics, were studied in aortic position. The prostheses were selected for the nominal annulus diameter reported by the manufacturers without any assessment of the valve sizing method. The hemodynamic function was investigated using a bidimensional LDA system. Results concern velocity profiles during the peak flow systolic phase, at high cardiac output regime, highlighting the different flow field features downstream of the four small-sized cardiac valves.

Aortic Valve↗

The clinical and radiological outcome of the rotating hinged knee prostheses in the long-term.

BACKGROUND AND AIMS: Opinions about hinged knee prostheses vary a lot in different studies. We wanted to examine our series in order to gain long-term information about this kind of knee prosthesis. MATERIAL AND METHODS: Forty-eight (18 Kinematic Hinge and 30 Link Endo Model) rotating hinged knee prostheses were implanted in the Hospital of Invalid Foundation. All knees were retrospectively followed up for an average of 66.3 months and examined for clinical or radiological factors indicating the overall outcome. RESULTS: In the latest review there were 10 patients (20.8%) regarded as having unsatisfactory and 35 patients (79.2%) satisfactory results. Eighty-four per cent of the patients were subjectively satisfied with the operation, mostly because of the painless result. CONCLUSIONS: Taking into account the very poor initial status of these patients, we recommend the rotating hinged prostheses still to be used in severely instable knees awaiting revision.

Adolescent↗

A prospective study on the maintenance of implant prostheses in private practice.

This study examined the adjustments, repairs, time, and costs required to maintain 69 implant prostheses in private prosthodontic practice for an average of 22 months after placement. For the removable prosthesis design, the most common adjustment was contouring the prosthesis and the most common repair was retentive component replacement. Screw tightening or fracture repair were the most frequently needed modifications for fixed implant prostheses. Each removable implant prosthesis averaged four times as many postplacement adjustments and almost twice as many repairs as did each fixed implant prosthesis, and the mean length of each maintenance appointment was also longer for removable prostheses. Mean repair costs were approximately 60% higher for the removable design.

Adult↗

The use of implant-supported ceramometal titanium prostheses following sinus lift and augmentation procedures: a clinical report.

This clinical report presents rationale and clinical procedures involved in the use of ceramometal implant-supported titanium-cast prostheses for the rehabilitation of patients with atrophic maxillae requiring iliac crest grafting procedures. Favorable clinical results have been obtained, although clinical observation periods have been limited. The present observations suggest that osseointegrated ceramometal titanium prostheses could form a valuable part of restorative therapy following augmentation procedures. Furthermore, these titanium prostheses may be a meaningful contribution to implant prosthodontics, facilitating restorations of optimum biocompatibility.

Adult↗

[The use of allografts in the surgical treatment of patients with infected vascular prostheses].

The article is devoted to analysis of surgical treatment of patients with such a dangerous complication as infection of the vascular prosthesis. The authors have performed 25 operations for substituting the infected prostheses for allografts. In 18 patients the infected prostheses were located in the aorto-iliac segment, in 5 patients in the femoro-popliteal segment, 1 patient had it in the aorta, and 1 in the subclavian segment. The prostheses were removed and a simultaneous revascularization was made. The authors make a conclusion that it is very expedient to use alloprostheses as a protective measure against persistent or recidivating infections. The allografts have both early and long-term resistance to infection.

Aged↗

Comparison of nerve regeneration through different types of neural prostheses.

Rat sciatic nerve regeneration through three synthetic neural prostheses was compared with regeneration through nerve allografts. The synthetic prostheses were either nonpermeable nonabsorbable (Silastic), permeable absorbable (polyglactin mesh), or permeable nonabsorbable (polypropylene mesh). Animals were evaluated at 10, 24, and 90 days. Functional analysis of nerve regeneration was performed by noninvasive methods: electromyography and walking tracks. Nerve tissue was examined with routine histologic and immunofluorescent techniques. A compressive neuropathy developed with the use of the Silastic implant. A neutrophilic inflammatory infiltrate was consistently associated with implantation of the polyglactin mesh. A strong connective tissue response was noted around the polypropylene mesh. Early recovery of nerve function was seen with the Silastic implants, however, overall nerve function was best in the nerve allograft and polypropylene mesh groups. Polyglactin implantation increases the local inflammatory response and should not be used for nerve anastomoses. If Silastic entubulation is used, it should be removed between 24 and 90 days.

Animals↗

Self-expanding prostheses complicating augmentation mammoplasties.

A new and serious complication was experienced by patients of three independent surgeons following routine augmentation procedures. In each case reported, double-lumen prostheses had been used. All cases were reoperated with a diagnosis of capsular contracture. However, at surgery it was found that the outer lumen of the prostheses had overfilled with 60-160 cc of interstitial fluid, probably because of an osmotic gradient. The possible causes of this unfortunate complication are considered.

Adult↗

A comparative study of the clinical results obtained with plastipore and ceramic ossicular prostheses in otologic surgery.

We describe our experience with clinical tolerance to total and partial ossicular prostheses using ceramic and plastipore and the functional results obtained. We have found that ceramic is well tolerated (with a 4% incidence of rejection) in contrast to plastipore (which had a 19% incidence of rejection). The ceramic partial and total prostheses give satisfactory function results, and 63% and 62% of our patients, respectively, were found to have postoperative air-bone gaps of less than 20 dB, and average air-bone gap gains of 16 and 21 dB.

Biocompatible Materials↗

Retinal replacement--the development of microelectronic retinal prostheses--experience with subretinal implants and new aspects.

BACKGROUND: Progress in the field of microelectronics has led to the development of visual prostheses for the treatment of blinding diseases. Different concepts of retinal replacement are currently under investigation. The aim of the retinal prostheses is to replace the function of lost photoreceptors in degenerative diseases, such as retinitis pigmentosa. METHODS: Within the field of visual prosthetic developments mainly two retinal based concepts are under investigation. One of the concepts is the epiretinal implant which acquires images of an external camera and after preprocessing by a computer reading this visual information into the human visual system. In the subretinal prosthesis design concept an array of stimulation electrodes is placed in the subretinal space. True to the concept the image falling on the retina and its light impulses are converted into electrical currents by microphotodiodes and the retina is stimulated with these locally. To test the feasibility of the concepts the biocompatibility and to determine basic stimulation parameters a lot of animal experiments and first human experiments were carried out. RESULTS: Currently the research conducted by teams in Germany, the USA and Japan into epiretinal and subretinal implants has reached the stage where clinical trials can now be performed. Individual pilot studies were carried out for both the epiretinal and the subretinal implant by different research groups. DISCUSSION: The results achieved by the researchers indicate that cortical action potentials can be triggered by electric retinal stimulation with both concepts. The experimental work has highlighted a whole range of obstacles, not all of which have yet been fully resolved. These findings offer hope that coarse restoration of vision may be feasible by electrical stimulation.

Animals↗

Numerical simulation of the superplastic forming of dental and medical prostheses.

A relatively recent development in prostheses manufacture is the use of superplastic forming technology formerly associated with industrial applications such as aerospace components. This paper considers the finite element incremental flow formulation for the simulation of the forming of thin and moderately thick titanium alloy sheet dental and medical prostheses and, in particular, the determination of the pressure-time cycle. Issues concerning material characteristics are discussed, and the process is illustrated by a number of examples. The application of finite element simulation in this context is ongoing, nevertheless interim conclusions are drawn and future directions for research are identified.

Biocompatible Materials↗

The uses of external nipple-areola prostheses following reconstruction of a breast mound after mastectomy.

Following reconstruction of the breast after mastectomy it is common practice to allow a "settling" period before grafting the nipple-areola complex. A selection of external nipple-areola prostheses are described which can be used until surgical reconstruction can be carried out and which are helpful in determining the correct position of the nipple-areola grafts. It has been found that some patients actually prefer to use the prostheses permanently for dress purposes rather than undergo an additional operation.

Breast↗

Stance phase control of above-knee prostheses: knee control versus SACH foot design.

The mobility of above-knee amputees (A/K) is limited, in part, due to the performance of A/K prostheses during the stance phase. Currently stance phase control of most conventional A/K prostheses can only be achieved through leg alignment and choice of the SACH (Solid Ankle Cushioned Heel) foot. This paper examines the role of the knee controller in relation to a SACH foot during the stance phase of level walking. The three-dimensional gait mechanics were measured under two stance phase conditions. In the first set of trials, the amputee used a prosthesis with a conventional knee controller that allowed the amputee to maintain the knee joint in full extension during the stance phase. In the second set of trials, the prosthetic knee, during stance, echoed the modified kinematics of the amputee's sound (intact) knee that had been recorded during the previous sound stance phase. Analysis and interpretation of the data indicate the following: (1) SACH foot design can strongly influence the walking mechanics independent of the knee controller; (2) knee controller design and SACH foot design are mutually interdependent; and (3) normal kinematics imposed on the prosthetic knee does not necessarily produce normal hip kinematics (e.g. reduce the abnormal rise in the prosthetic side hip trajectory). Future research is necessary to explore and exploit the interdependency of prosthetic knee control and foot design.

Amputees↗