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[Hemopoietic response to americium and plutonium exposure in nuclear industry workers].

The examinees demonstrated definite effects caused by total influence of Am-241 and Pu-239: chronic radiation sickness with diffuse pneumosclerosis, chronic toxic radiation bronchitis and peripheral blood changes (reactive alterations and stable lower platelets and reticulocytes count), microfocal hypoplasia, osteodysplasia, reactive hepatopathy. Frequency of these effects increased with higher radiation exposure and did not depend on the age.

Americium↗

[Dosage of irradiation of the population in the Bryansk region with plutonium deposited in the soil after the Chernobyl AES accident].

Proceeding from the data on 238Pu, 239Pu, 240Pu concentrations in the soil in different areas of the Bryansk Region, exposed to radioactive contamination after the Chernobyl accident, radiation dose exposures of residents as well as agricultural workers were assessed. Criteria of the ecological and radiation-hygienic standardization were used for calculation of values of dose factors, binding the alimentary and inhalation components of an irradiation dose with characteristics of Pu deposition in the soil. Inhalation of soil particles accounted for approximately 90% of a total radiation dose of the "soil" Pu component, and the alimentary component-for approximately 10% (of this, 99% were attributed to plant products). The authors proposed prognostic assessment of an expected effective equivalent dose for a period of 70 years for people, residing in these areas (0.08-0.45 cSi for the population and 0.6-3.2 cSi for mechanics).

Accidents↗

Health considerations for workers exposed to plutonium.

It is interesting to observe that today the discussions, public concerns, and legal battles over health risks presented by Pu are not only vigorous but also accelerating. Our knowledge of the biochemistry, pathophysiology, dosimetry, and radiobiology of Pu has increased enormously during the intervening 45+ years since the first experiments. For the first time in the history of science and industry, extensive epidemiologic studies are being conducted on the majority of all people in this country who have worked with a material since its introduction and before anyone has had any known acute or chronic illness from exposure to it.

Animals↗

[Lung histopathology during plutonium-238 incorporation].

In experiments with albino mongrel female rats a study was made of the response of the lungs to a single intratracheal injection of nitrate of 238Pu (0.4-740 kBq/kg). The nature of the inflammatory disease, the lymphoid tissue condition, pneumosclerosis occurrence, and the frequency and spectrum of lung tumors were shown to be a function of dose of the radionuclide administered.

Animals↗

[Effect of lowered relative humidity of the air on the accumulation of plutonium-239 in the body and its biological effectiveness].

The experiments on rats show that the 4-month elevated air dryness has no impact on body accumulation of 239Pu but causes more distinct forms of bronchitis and interstitial pneumonia combined with the strain in medullary hemopoiesis and reactivity intensification of pulmonary and B-system immunity. Under prolonged effect of both factors a breakdown in fully adequate immune response can occur.

Air Pollutants↗