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At least 919 records · Page 51Linked to original sources
PubMed2002

A personal response to Gail Hornstein's To redeem one person is to redeem the world: the life of Frieda Fromm-Reichmann.

This article summarizes events surrounding the closing of Chestnut Lodge, as a backdrop to the author's reactions on reading Frieda Fromm-Reichmann's biography. This anecdotal piece forms a complementary essay with the 2000 Frieda Fromm-Reichmann Lecture, "The Current Relevance of Fromm-Reichmann's Works." It illustrates aspects of treatment of schizophrenia and of the individuals involved in such work.

History, 20th Century↗
PubMed1999

Reactions of healthy persons and persons suffering from allergic rhinitis when exposed to office dust.

OBJECTIVES: Reactions to airborne office dust among healthy subjects and subjects suffering from allergic rhinitis were investigated. METHODS: Twelve healthy and 11 subjects suffering from allergic rhinitis were exposed to clean air [17 (SD 2) microg/m3] and office dust [439 (SD 68) microg/m3] for 245 minutes. The effect measurements included subjective sensations (questionnaire and potentiometer ratings), mood scale, peak flow, bronchial provocation with histamine using forced expiratory volume in 1 second as the effect measure, nasal mucosal swelling, tear film stability, epithelial damage, foam formation in the eye canthus, threshold for eye irritation with carbon dioxide, eye redness, cellular content of conjunctival fluid, and an addition test for distraction. As many investigations were made and as many statistical analyses (including subgroup analyses) were carried out, the risk of mass significance appeared. This problem was dealt with using the Bonferroni correction for multiple significance tests. RESULTS: The mean ratings of the potentiometer were higher (the subjects showed more irritation) during the dust exposure. The objective investigations showed only indications of effects of dust exposure, and some of the indications were in biologically unexplainable directions. No difference in the reactions to dust was observed between the healthy subjects and the subjects suffering from allergic rhinitis. CONCLUSIONS: Dust does not seem to have objective or subjective effects on humans, as only indications of dust effects were found. Subjects suffering from allergic rhinitis do not appear to be a risk group in relation to dust exposure.

Adolescent↗
PubMed1976

[Rubella vaccination with "Cendehill" and "RA 27/3". Reinfection of vaccinated and naturally immune persons compared with the infection rate of susceptible persons within a 3-resp. 5-year observation period (author's transl)].

Many investigators in Europe and the USA have usually found high rates of serum conversion after vaccination with the rubella vaccines Cendehill and RA 27/3, but the resistance of vaccinated individuals against superinfection without disease induced by wild virus strains under experimental or natural conditions seems to be very low; e.g. up to 80% of the vaccinees reacted with increasing titers of hemagglutination inhibiting antibodies after super-infection with a wild virus in a special epidemiological situation. In our two studies performed under natural conditions of infection including an observation period of three years resp. five years after vaccination a more favourable picture evolved, perhaps reflecting a different epidemiological situation, a different susceptibility or a less virulence of wild virus in our region: Three years after vaccination of 14 years old girls with Cendehill and RA 27/3 in a double blind trial a significant increase in the titers of hemagglutination inhibiting antibodies was observed after vaccination with Cendehill by the subcutaneous route in only 1,16% (1/86) and in 1,18% (1/85) after vaccination with RA 27/3 by the same route. In the same observation period the infection rate in a control group not protected by natural immunity or by vaccination was 54,72% (87/159) and in a second control group, protected by natural immunity 1,82% (3/165)...

Adolescent↗