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[The "robotron NATALI" microcomputer-assisted birth monitoring system].

The microcomputer system "robotron-NATALI" from VEB Kombinat robotron Dresden, GDR, is applicable for bed side-monitoring and disposed about a new graphical representation of CTG's for fetal condition and uterine activity. A dialogue between physician or nurse and the computer is possible. After parturition all administered data are printed out in form of a partogram, inclusive the graphical representations during labor.

Computers↗

[Microcomputer applications in otorhinolaryngology (author's transl)].

Two main types of utilisation of microcomputers in otorhinolaryngology are envisaged: instrumentation and medical audit. The modes of employ of the material in these fields are briefly exposed, followed by the presentation of several examples of its employ and functioning. Practical notions are discussed, particular emphasis then being placed on theoretical considerations involved in the use of such equipment. Of primary importance are strictly medical reflections, problem solving being facilitated (by suppressing or diminishing routine tasks) but never simplified.

Computers↗

[Use of a microcomputer for simplified data processing of ENT case-records employing a commercial program (author's transl)].

Combined use of a microcomputer of sufficient capacity and a commercial program for data processing permits simple storage and exploitation of hospital case-records in an ENT department of moderate size. The principal advantages of the system reside in its permanent availability, the ease of communication with the computer due to the clear language employed, its large storage capacity (650 case-records per diskette), and the moderate cost involved. Programming time is reduced by the use of a particular nomenclature for questions and possible replies. The system is not static, and can be adapted to individual needs or modifications in pathology.

Computers↗

The microcomputer in medical instrumentation. Aspects of an automated monitoring system.

The major technical trends in medical computing include sensor devices and artificial intelligence techniques. Use of the computer will render instruments more accessible and make them friendlier to the user. Examples include automation of gain setting in echocardiology and instant computation of M-mode data. In intensive care units, computers have become an integral part of patient monitoring over the last two decades. Third generation microcomputer-based systems are presently helping to solve many earlier problems. Features such as touch-sensitive keys or screens (eliminating keyboards) and integrated front-end are greatly increasing user acceptance. A new monitoring system developed at the Thorax Center for intensive cardiac patient monitoring and provided with these features will be described.

Computers↗

The microcomputer as an aid to medical records management in a zoological park.

A system for computerizing clinical medical records at a zoological park was designed, using microcomputer system components. Records were entered and retrieved in natural language, with minimal coding of information. Commercially available computer programs were used to manage data from anesthesia, radiography, clinical pathology, vaccination records, and tuberculin testing records. Programs written in BASIC language were used for storing and retrieving animal inventory data, daily medical and surgical records, results of fecal examinations, and anthelmintic treatment records.

Animals↗

A menu-driven, touch panel microcomputer for clinical recordkeeping.

Quikchart is a menu-driven, touch-panel input microcomputer system designed for computer-naive physicians active in clinical environments. It enables them to generate patient encounter records, and to store and access them using electronic memory. It also permits printing hard-copy records. The system is designed so that the physician can do all this without resorting to a standard typewriter or computer keyboard. It circumvents the disadvantages of both handwritten records and dictated records. Upward expansion of Quikchart will allow individual systems to be networked into a clinic-wide medical record system.

Computers↗

Microcomputer applications in biomedical research.

Microprocessors and microcomputers are assuming an increasingly important role in clinical and biomedical research. They are applied to the development of new devices for monitoring patients, replacing lost physiologic or sensory function, or performing therapeutic procedures. In research laboratories, microprocessors help to automate instrumentation for measurement and control and to control data collection and analysis functions. Several applications from the National Institutes of Health described by the author illustrate some of these uses.

Computers↗

[Use of a microcomputer system in radiotherapy (author's transl)].

The authors report their experiences with the successful use of a microcomputers system in radiotherapy. A self-developed programme allowing the calculation of depth dose and irradiation times in telecobalt therapy is given as an example for the application of this system. The authors put stress on a simple handling (video dialogue) and a written documentation. The programme can easily be modified for the use of other telecobalt devices.

Cobalt Radioisotopes↗

[Derived potentials and the microcomputer (author's transl)].

A method for conducting "brain stem early derived potentials" using an inexpensive microcomputer is described. This type of examination is, however, difficult to perform, and is not currently employed in clinical practice. The contribution offered by this data-processing system is emphasized.

Analog-Digital Conversion↗

[The use of the microcomputer in selecting the basic cause of death].

The article begins with a discussion of some mortality statistics issues, problems encountered in the manual selection of underlying cause of death, and also the increasing need for information on associated causes. These circumstances led the National Center for Health Statistics to develop the computerized ACME System, which has been in use in São Paulo State since 1983. The ACME System's requirement of a mainframe computer, as well as other operational limitations, has prevented its installation throughout the country. In order to standardize and improve the quality of mortality data in Brazil, the Informatics Department of the Ministry of Health's National Health Foundation and the World Health Organization (WHO) Collaborating Center for the Classification of Diseases in Portuguese developed the microcomputer-based Underlying Cause Selection System (SCB) in 1993. This is an expert system that employs artificial intelligence techniques to reproduce the reasoning of a coder in selecting the underlying cause of death, according to the rules and provisions of the Ninth Revision of the International Classification of Diseases. The SCB has a very user-friendly interface, occupies 2.6 megabytes of hard disk space, and can run on any 386 or higher XT or AT computer. In addition to selecting the underlying cause of death, the system stores data on associated conditions.

Artificial Intelligence↗

Bronchospasmolytic activity and toxicity modelling of theophylline derivatives by a microcomputer based method.

The OASIS (Optimized Approach based on Structural Index Sets) microcomputer system was applied to model the bronchospasmolytic activity and toxicity of theophylline derivatives. The geometric and electronic factors responsible for biological activity of these compounds were determined. The molecular topology rather than compound metrics is the factor conditioning the theophylline activity. The opposite influence of topology on bronchospasmolytic activity and toxicity was established. Although the acceptor properties (acceptor superdelocalizability indices) determine both the activity and toxicity of the studied compounds the different positions of these effects is of decisive importance in both cases.

Bronchodilator Agents↗

[The microcomputer study and processing of the values of the blood pressure and intersystolic interval in laboratory animals].

A system is created for study of the agents, affecting the arterial pressure and baroreflectory sensitivity, which comprises:transducer for arterial pressure Statham P23 ID, connected to a polygraph Biomedica O.T.E.; eight-bite analogous-numerical transformer; microcomputer, compatible to Apple 2+; two diskette devices and printer. The arterial pressure of the lab animals (rats, rabbits, cats) is directly measured in a. carotis communis by means of the transducer and is recorded on the polygraph. For the system a computer program is designed which allows archivation of the primary experimental data; automatic and precise determination of the momentary values of the systolic and diastolic arterial pressure and intersystolic interval; determination of the baroreflectory sensitivity by means of linear regressive analyses; printing of the results under the form of diagrams and tables. By means of this system much time is spared, related to the accounting and handling of the experimental data.

Analog-Digital Conversion↗

A comprehensive microcomputer-based medical records system with sophisticated preventive services features for the family physician.

BACKGROUND: Computer-based medical records systems improve the provision of preventive services in the offices of family physicians. Until recently, these systems were either not commercially available for use by practicing physicians or were very expensive. METHODS: A commercially available, microcomputer-based medical records system is currently used at the Department of Family Medicine at the Medical University of South Carolina. This system is used as a fully electronic medical record and has sophisticated health maintenance tracking and reminder features. These features track the provision of preventive services, provide physician reminders at the time of patient visits, permit generation of mailed patient reminders, and provide reference to relevant patient education resources. RESULTS AND CONCLUSION: The system described in this paper can be used by practicing physicians to improve their delivery of preventive services.

Ambulatory Care Information Systems↗

The design and application of microcomputer human body information balance diagnosis and treatment instrument.

In Chinese medical theory, it is thought that if the "Yin and Yang balance, person will be healthy." Chinese medicine studies the human body as a whole which has specific functions. Chinese medical main and collateral channels are confirmed by experts at home and abroad as Ra kind of internal structure system that really exists.S It has been confirmed that imbalances caused by almost all diseases can be reflected in main and collateral channels system; the channels can adjust and control the physiological function and pathological expression of human body's viscera and bowels. The adjustment for the human body can be accomplished through reaction points of body surface and main and collateral channels. Since 1989, the studies of other countries have confirmed that the human body is a combined control system that owns various adjustment mechanism. The adjustment and control for human body state can be accomplished through biological information. Based on the above theory, the authors of this paper designed the instrument that can make diagnosis and treatment automatic. Biological information sensors are attached to the points of main and collateral channels, and they sense the signals of disease of the human body. Through an A/D converter, the signal is input into a microcomputer. The CPU makes a comprehensive analysis and diagnosis according to the program and the signs and amplitude of signal deviation values detected from the left and right main and collateral channels points; it gives relevant information treatment prescription. After D/A converting, the information treatment wave generator is activated. The composed information wave treats the human body through the main and collateral channels points, and the changes after treatment are fed back to the computer through biological information sensors to amend the treatment prescription and generate the new information treatment combination wave, which is again fed back. At last, the body system will reach stability and balance through many circulations. Through 300 cases of clinical practice, the total effective rate for 22 kinds of disease such as stomach ache, coronary heart disease, and Meniere's disease reaches 90.0%. Among these, the marked effect accounts for 7.3%; the improvement accounts for 82.7%. After processing by statistics, it shows that the instrument has a marked curative effect. In theory, the instrument has the functions of diagnosis, treatment, health care, adjustment of body immunity, prevention of cancer, the curing of nerve functional diseases and some nerve and spirit diseases, etc. It is estimated that the instrument will be used in more fields; it has good application prospects, and will become a new therapy in home medical care.

Analog-Digital Conversion↗

[A portable microcomputer analyzer of cardiac rhythm].

A portable and easy-to-use analyzer of cardiac rhythms is described. The device is based on an Elektronika MK-85M microcomputer and works on the principle of variational pulsometer which determines the status of the autonomic nervous system.

Electrocardiography↗

A microcomputer-based transplantation registry.

We describe a microcomputer-based program developed for the Brazilian Kidney Transplant Registry. The system can construct life tables and survival curves online, without the need to export the database. From 1987 through 1993, 6069 kidney transplants were reported; 3485 (57.4%) were from living donors and 2584 from cadavers. The proportion of cadaveric transplants increased from 28.5% in 1987 to 58.1% in 1993. Overall kidney transplantation activity was 8.1 patients per million population per year. Sixty-four percent of the patients were male, and 71% were white. The mean age was 33.4 years. The primary renal diseases most frequently reported were glomerulonephritis (43.6%) and hypertensive renal disease (13.6%). Only 3.6% of the recipients were diabetic. Patient and graft survival rates have improved in recent years. We expect that cadaveric organ procurement programs will continue to develop in our country, increasing the number of organ transplantations and creating a more equal distribution of cadaveric organs.

Adolescent↗

Development of a microcomputer-based system to monitor healing from injury.

It is well documented that induction of electric current in bone not only prevents the bone loss of functional disuse, but also induces new bone formation. Moreover, the literature suggests that the skeletal response is optimal at a distinct frequency range 10-30 Hz. Indeed, even at peak strains, well below those typical of habitual physiological loading, applications of 30 Hz were shown to be osteogenic. This evidence supports the concept that inducing even very low strains may generate an effective osteogenic stimulus, provided that they are induced at optimal frequency (10 to 30 Hz). Bone appears to respond with greater selectivity and sensitivity to this frequency range of electrical stimulation. Inducing insulin-like growth factors, which are negatively charged, will provide the required electrical stimulus. Traditionally, the progression of the cellular events during trauma is normally followed by x-ray to determine a healing rate. Frequent use of this method can result in serious side effects to the vital and reproductive organs. The objective of this study is to develop a microcomputer-based system to monitor the cellular events associated with healing. The system is capable of transmitting an electrical signal directly to the site of injury to improve the healing process and to monitor the progress of osteogenesis. The system consists of a base unit and implanted units. One implanted unit will be inserted in the femur with induced trauma and the other implant will be in the control femur. The base unit will transmit low frequency electromagnetic waves to the implanted units as well as receive periodic information about the ion movement in both femurs.

Biosensing Techniques↗

Microcomputed tomography imaging of skeletal development and growth.

Skeletogenesis is an exquisitely orchestrated and dynamic process, culminating in the formation of highly variable and complex mineralized structures that are optimized for their function. While cellular and molecular biology studies have provided tremendous recent progress toward understanding how patterns of bone formation are regulated, high resolution imaging techniques such as microcomputed tomography (micro-CT) can provide complementary quantitative information about the progressive changes in three-dimensional (3-D) skeletal morphology and density that occur during early skeletal development and postnatal growth. Furthermore, recently developed in vivo micro-CT systems promise to be a powerful and efficient tool for noninvasively monitoring normal skeletogenesis, as well as for evaluating the effects of genetic or environmental manipulation. This review focuses on the use of micro-CT imaging and analysis to better understand normal and abnormal skeletal development and growth.

Animals↗