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[Combined surgery of vitrectomy and intraocular foreign body extraction].

In combination with vitrectomy, plus lensectomy, optic iridectomy, or IOL implantation as indicated, 121 cases of intraocular foreign body extraction were performed, in which 75.2% of the f. b. were non-magnetic, the number of f. b. in one eye ranged from 1-7, and 93.1% of the vitrectomy were of the closed type. The extraction of f. b. was successful in 97 (80.2%) of the cases on the first attempt, and the total success rate was 96.7%, including those of secondary operations. The instrumentation and procedures involved were also reported.

Adolescent↗

[Treatment of explosion injury in 30 eyes by keratoplasty].

26 cases (30 eyes) of explosion injury were treated by keratoplasty, with the results that 70% of the grafts were clear, 50% escaped blindness, and a total of 76% had their vision improved. In nine cases of severe injury in the anterior segment with little light perception, reconstructive keratoplasty was performed to keep the eyeballs successfully in seven cases, among whom five cases obtained transparent grafts. The procedure included partial keratectomy, iridectomy, lensectomy, anterior vitrectomy, keratoplasty, and reconstruction of the anterior chamber to restore cosmetic shape of the eyeball. The author deemed keratoplasty valuable in the treatment of ocular explosion injury.

Adolescent↗

[Injurious effects on the rhesus monkey eye from dye laser iridotomy].

8 normal rhesus monkeys were performed dye laser iridotomy in one eye and iridectomy surgery in the other. Another 7 normal rhesus monkeys were performed dye laser iridotomy in one eye and ruby laser iridotomy in the other. The protein content and the number of white blood cells in the aqueous humor, the intraocular pressure, and the ultrastructural changes in the pars plicata of the ciliary body and iris were observed after the operation. It was demonstrated that the intercellular space of the endothelium of the blood vessels in the iris might, like the intercellular space of the non-pigment epithelium in the pars plicata of the ciliary body, be the site of the blood-aqueous barrier of the eye. It was also shown that among these three modalities, dye laser iridotomy was the best, which induced the least injury to the blood-aqueous barrier with the shortest time for recovery and the least inflammatory reactions in the anterior segment of the eye.

Animals↗

[Eye care in Greenland in 1979-1988].

Specialist eye care in Greenland is described on the basis of 66 reports from all 30 visiting consultants during a ten-year period. During this time the durations of the visits increased to approximately seven months per year for 8-9 ophthalmologists who undertook approximately 2,500 consultations annually. The diagnoses were distributed as follows: 30% anomalies of refraction, 15% cataract, 12% conditions in the posterior segment and 10% glaucoma, i.e. a considerable proportion of eye diseases associated with advancing age and with a particular Greenlandic influence. The workload was particularly great and averaged more than a reasonable weekly load despite the increase in number of days of employment. Until 1985-1986, eye surgery activities showed a considerable increase after which operative interventions for cataract and glaucoma were mainly referred to Rigshospitalet. The great increase in the number of referrals is discussed in relation to the marked changes in the therapeutic possibilities for cataract and glaucoma: extracapsular cataract extraction with posterior chamber implantation using an operation microscope and YAG-laser iridectomy of early angle closure glaucoma. The requirement of an eye surgical unit in Greenland appears to be pressing together with continuation of specialist eye care in the districts.

Aged↗

Update on the management of glaucoma.

Most cases of chronic open-angle glaucoma can be treated medically. When medical management is ineffective, laser trabeculoplasty is usually performed. If medical management and laser treatment fail, surgery is the next step. Recently, ultrasound has been employed successfully for control of glaucoma when medical, laser, and surgical treatments were not successful. Acute angle-closure glaucoma is an ophthalmic emergency. This condition can be treated at an early stage by relieving the pupillary block with peripheral iridectomy by laser or surgery. Four major classes of drugs are currently used to treat glaucoma: carbonic anhydrase inhibitors, beta adrenergic blockers, parasympathomimetics, and sympathomimetics. Both local and systemic side effects may occur secondary to glaucoma medications and some of these may be severe or even fatal. These adverse reactions are discussed.

Glaucoma↗

[Pars plana vitrectomy with implantation of silicone oil in surgery forvery large retinal tears].

The authors evaluate the results of pars plana vitrectomy (PPV) with intravitreal implantation of silicon oil (ISO) in 19 eyes of 17 patients with gigantic tears of the retina. During the mean observation period of 22 months the operation was successful in 15 of 19 eyes (78%). The retina adhered on the entire surface in 12 eyes (65%), in three eyes (15%) there remained a defined flat elevation of the retina in the periphery of the lower half of the fundus which did not go as far as the macula. In successfully operated eyes the visual acuity was 0.4 in two eyes, visual acuity of 0.3-0.1 in 7 eyes and visual acuity less than 0.1, making spatial orientation possible, in six eyes. The cause of reduced visual acuity of successfully operated eyes were macular abnormalities which were associated with the fundamental disease, degenerative myopia, injury, impaired nurture of the macula during prolonged detachment, a membrane-forming process. As to late complications of ISO, the most frequent were glaucoma in 42% and complicated cataract u 78% phakic eyes. Extraction of a cataract with iridectomy VI and supplementation of silicon oil into the intravitreal space did not cause in any of the patients a relapse of detachment of the retina. The final evaluation of PPV with ISO in the surgery of gigantic lesions of the retina will be possible only after the long-term follow up of larger groups of patients.

Adolescent↗

[Pseudo-exfoliation syndrome as a risk factor for vitreous loss in extra-capsular cataract extraction. The Erlangen Eye Information Group].

A prospective study for evaluation of the pseudoexfoliation syndrome (PES) as a risk factor in extracapsular surgery was undertaken from February 1986 to June 1988. The study included 2042 planned extracapsular cataract extractions performed by 12 surgeons. Seventy-two eyes revealed PES (3.5%). Frequency of PES increased with age (p less than 0.005). The male-female ratio of PES was 1:1.6, and eyes of average axial length showed PES more frequently than myopic or hyperopic eyes, although these differences were not significant statistically. The incidence of vitreous loss was 11.1% in eyes with PES and 1.6% in eyes without PES, a sevenfold increase that was statistically significant (p less than 0.0001). Rupture of the posterior lens capsule was observed in 4.2% of PES eyes compared to 2.8% of eyes without PES (no significance). The pseudoexfoliation syndrome is not a harmless anomaly, but a potentially disastrous disease of the anterior segment of the eye. As precautionary measures we recommend thorough biomicroscopic examination preoperatively for signs of PES, iridotomy or sector iridectomy in cases with poorly dilating pupils, very gentle manipulation intraoperatively, and posterior chamber lens sulcus implantation in eyes with zonular defects or phacodonesis.

Adolescent↗

[Keratopathy following vitrectomy with silicone oil injection].

We present a retrospective study on keratopathy following vitrectomy and injection of SF96 silicone oil (viscosity 1000 centipoise, n = 232 eyes) and the purified OP 1000 silicone oil (viscosity 1000 centipoise, n = 129 eyes). In cases with aniridia, with closed inferior basal iridectomy (IBI) or without IBI, keratopathy was found in 74 of the 166 eyes (45%) injected with silicone SF96 and in 14 of the 30 eyes (47%) injected with silicone OP 1000. An intact IBI reduced the incidence of keratopathy to 0% (SF96, 0/45 eyes) or 6% (OP1000, 5/88 eyes) when the anterior chamber was free of silicone. When silicone oil was in contact with the corneal endothelium (due to periretinal reproliferation, hypotony, overfilling or droplet formation), there was corneal decompensation in 66% (SF96, 14/21 eyes) or 55% (OP1000, 6/11 eyes). The keratopathy presents as calcified band keratopathy or diffuse bullous corneal edema as in "endothelial decompensation." These variations in keratopathy are in agreement with the following basic diagnoses: 77% (43/56 eyes) of trauma patients (n = 130) develop calcified band keratopathy, and 47% (24/51 eyes) of patients with idiopathic proliferative vitreoretinopathy (n = 182) present with diffuse bullous corneal edema.

Cornea↗

[Long-term follow-up following posterior chamber lens implantation with defective or absent posterior chamber].

41 patients were follow up in whom a posterior chamber lens was implanted despite of ruptured posterior capsule. Follow-up period was 9 months to 5 years: 30 lenses were well centered, 7 were slightly decentrated, 2 were strongly decentrated. In 2 cases the lens was luxated into the vitreous. CME was observed in two cases and retinal detachment in 5 cases. In 6 selected patients without posterior capsule, a 2-loop PCL (Simcoe-type) was implanted by controlled suture-fixation into the ciliary sulcus. The inferior haptic was sutured directly in the 6 o'clock position while the superior haptic (12 o'clock) was fixed indirectly by an "iris flap" (made from the "iridectomy") which was turned posteriorly. Follow-up period of 1-2 years: no decentration, vitreous in the anterior chamber in 2 cases.

Follow-Up Studies↗

[Basal iridotomy as one of the crucial stages in the surgical treatment of cataract].

Results of extracapsular cataract extraction performed in 197 patients are analysed. Of them, peripheral iridectomy was made in 115, and iridotomy in 82 patients (in 10--parallel to limbus, in 72--radially towards limbus). The best results were recorded in patients with radial basal iridotomy: no complications were practically observed, manipulations in the posterior and anterior chambers of the eye were less dangerous, good visual and cosmetic results were obtained with a considerable shortening of postoperative bed-days.

Adult↗

Deep sclerectomy with trabeculotomy ab externo: one-stage procedure (DS 1).

Our new full-thickness filtering procedure was performed on 20 eyes with narrow-angle glaucomas (15 patients, mean age 69 +/- 12 years) with high intraocular pressure (IOP) despite initial peripheral iridectomy. This procedure was intended to maintain anterior chamber depth completely during intraoperative and postoperative periods. Under conjunctival and thin scleral flaps, the deep (4 X 1.5 mm) scleral block containing the outer wall of Schlemm's canal was removed. After closing the scleral flap with eight interrupted sutures and the conjunctival flap with a running suture, a 1-mm spatula was inserted beneath the scleral flap, and the trabeculum was punctured. The mean preoperative and final postoperative IOPs were 34.8 +/- 17.2 mm Hg and 14.9 +/- 4.9 mm Hg, respectively. Follow-up time was at least 12 months. Final postoperative IOP was less than 21 mm Hg without oral medication in 16 eyes (80.0%). The only complication was slight bleeding from the punctured trabeculum. This bleeding was completely absorbed within a week.

Adult↗

Modern simple extracapsular surgery.

A series of 444 aphakic eyes is reviewed in which extracapsular extraction was performed by modern simple instrumentation followed by the insertion of a posterior chamber lens. The visual results of 93.5 per cent seeing 6/12 (20/40) or better in an age group of 70 years plus is satisfactory. The hospitalization is short and visual recovery rapid. Complications have been few and it has been shown that peripheral iridectomy is not required in most cases as they are not subject to pupil-block glaucoma. The main problem with extracapsular extraction is the incidence of needlings of 9 per cent rising to 16 per cent with longer follow-up. Despite this it is felt that the advantages of extracapsular extraction, with rapid visual rehabilitation and a lower incidence of cystoid macular oedema and retinal detachment, outweigh the disadvantages.

Aged↗

[Secondary glaucoma and uveitis: hypertensive uveitis (author's transl)].

The secondary rise of i.o. pressure in uveitis may lead to a true secondary glaucoma or to hypertensive uveitis. The etiology of the endogenous inflammation does not seem to play a role. Pathogenetically the occlusion of the pupil with the formation of iris bombé and the obliteration of the chamber angle by exudate are important factors, while the hypersecretion of aqueous humor plays a minor role. Medical treatment consists in mydriatics and steroids. Surgical treatment depends on the pathogenetic mechanism and consists either in sector iridectomy or a filtering procedure.

Behcet Syndrome↗

Corneal decompensation following acute angle-closure glaucoma.

Ten eyes of nine patients with endothelial dystrophy requiring iridectomy for acute angle-closure glaucoma developed corneal edema sufficient to require penetrating keratoplasty. Because of the proximity of iris to cornea, simultaneous lens extraction was carried out to prevent malignant glaucoma. Penetrating keratoplasty using techniques presented here provided improved visual acuity and control of glaucoma in all cases.

Acute Disease↗

Intravitreal antimycotic therapy and the cure of mycotic endophthalmitis caused by a Paecilomyces lilacinus contaminated pseudophakos.

A salvaged eye in a case of mycotic endophthalmitis is reported. The case was one of eleven in the United States resulting from Luminex lens implants contaminated with amphotericin B resistant Paecilomyces lilacinus, and one of two eyes salvaged in this series of cases. The fungus, recognized 28 days after the lens was inserted, was in the anterior chamber, on the psuedophakos, and in the vitreous. The therapeutic procedures included removal of the pseudophakos, radical vitrectomy and iridectomy, and the intraocular and combined topical and systemic use of antimycotic compounds, including miconazole and thiabendazole.

Aged↗

Hereditary lens dislocation with angle closure glaucoma.

Eight patients in one family showed dislocation of the lens and secondary angle-closure glaucoma coming on in the 50's. They all displayed the sequence of myopia, angle shallowing, followed by angle-closure glaucoma. This sequence should alert the clinician to the possibility of a hereditary disease. The cause of the disease is unknown. It is suggested that treatment should be an iridectomy in the early stages and a lens extraction if glaucoma develops.

Age Factors↗

[Twenty-five years of experience with corneal grafts (author's transl)].

The progress in instrumentation and surgical techniques, as well as improvements in the knowledge of the biologic mechanisms have considerably enlarged the indications for keratoplasty. Even in unfavourable cases the prognosis has been notably improved by recent advances in medications and techniques to improve the conditions of the recipient and the operative technique, and also to limit the immunologic response. The use of impeccable instruments, meticulous selection of the graft and a refined surgical technique during the the operation are essential since neglect of any small detail may lead to failure of the operation. The graft and the recipient bed must be in perfect apposition. A very neat, smooth incision of the graft and the host window are imperative, as well as the application of a sufficient number of sutures. The sutures must be left in place for a sufficiently long period of time to ensure good cicatrization of the graft. Peripheral iridotomies or iridectomies facilitate the circulation of the aqueous humor avoiding the danger of postoperative pupillary block with all its consequences. The anterior chamber must be carefully restored, preferibly by air injection, to maintain the iris well away from the incision. It should be taken into account during the whole procedure that the endothelium is the most delicate and the most important structure of the graft as well as the host cornea. Contact with the instruments should be avoided and the sutures should provide good apposition of the endothelial edges. Early diagnosis and prompt adequate treatment of any accident or complication are essential. Undetected complications or incorrect management of the same may be responsible for failure of the operation and the final result may vary between a more or less opacified graft and the full-blown picture of phthisis bulbi. A number of illustrative cases are presented.

Adult↗

[Experimental and clinical use of the thermal mode neodymium:YAG laser].

The neodymium:YAG laser may be used to advantage in the thermal mode for iridectomy. A variety of other tasks which are traditionally performed using the argon laser can also be efficiently carried out using this mode of operation. In this article the authors describe in particular the method of transscleral cyclophotocoagulation with the neodymium laser in the treatment of glaucoma, which is becoming increasingly popular.

Animals↗