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At least 919 records · Page 51Linked to original sources
PubMed1975

Lumbar myelography with meglumine iocarmate and metrizamide.

Metrizamide and meglumine iocarmate (Dimer-X), which at present are the contrast media for myelography best tolerated by central nervous system, were compared in a double-blind test comprising a total of 86 patients, all with symptoms of lumbar or sacral root involvement. Symptoms appearing were recorded using a standard interview formula 24 hoaurs after myelography. EEG, routine laboratory analyses of CSF and neurologic examinations were also made. In some cases CSF paper electrophoresis, CSF pressure recordings and determination of CSF iodine content were obtained.

Adult↗
PubMed1975

Side effects after lumbar myelography with dimeglumine iocarmate (Dimer-X). Further experiences.

Lumbar myelography with dimeglumine iocarmate was performed in 90 cases premedicated with diazepam (Valium). EEG was performed before, as well as 3 and 24 hours after myelography. The use of diazepam interfered to some extent with the interpretation of the EEG. In 3 cases EEG abnormalities occurred 3 hours after myelography, most probably ascribable to Dimer-X. No further changes were found in the 24-hour recording. Immediate side effects were few and mild and seizures did not appear. The EEG abnormalities were equally distributed among patients with and without side effects.

Adolescent↗
PubMed1975

Elimination of water-soluble contrast media from the subarachnoid space. Investigation with computer tomography.

Contrast media injected into the subarachnoid space may be eliminated in two different ways, by diffusion through the meningeal membranes or by transport through these CSF pathways. The latter mode of transport may be examined using computer assisted tomography of the head. Diffusion predominants with contrast media of low molecular weight, such as methiodal sodium. The transport through the CSF cihculation increases when contrast media of high molecular weight such as meglumine iocarmate and metrizamide are used.

Diagnosis, Computer-Assisted↗
PubMed1976

Adverse effects of lumbar myelography with amipaque and dimer-X.

The adverse effects in a series of 50 lumbar myelographies with Amipaque were compared with those in a corresponding series, examined with Dimer-X. Side effects occurred in 58% of the cases examined with Amipaque and in 68% of the Dimer-X series. No seizures occurred in 58% of the cases examined with Amipaque and in 68% of the Dimer-X series. No seizures occurred in either series but slight fibrillations of fasciculations appeared in 2 Dimer-X patients. Hyperreflexia of the legs was recorded in 22% of the Amipaque and in 36% of the Dimer-X cases. Other adverse reactions to the media were mild to moderate. Some burst activity, but no definite paroxysmal abnormality was noted in EEG recordings in 2 Amipaque cases. The low epileptogenicity of Amipaque has ensured a wider safety margin of lumbar myelography.

Adult↗
PubMed1979

Influence of contrast media osmolality on isolated rabbit heart performance.

A low osmolality contrast medium (Iopamidol) caused less cardiac disturbance on isolated rabbit heart than a high osmolality medium (Urografin). The same effects were induced by glucose solutions iso-osmolal with the two media. After perfusion with Propranolol (1 microgram/ml) and Cimetidine (1 microgram/ml) the observed effect was unaltered.

Animals↗
PubMed1980

Proteinuria following nephroangiography. V. Influence of calcium and magnesium ions in non-ionic contrast media.

The influence on albuminuria following nephroangiography was investigated after addition of Ca2+ to the non-ionic contrast medium metrizamide (Amipaque) in the rat and after addition of Ca2+ or Ca2+ and Mg2+ to the experimental non-ionic contrast medium C 29 in the dog. When Ca2+ or CA2+ and Mg2+ were added to metrizamide or C29 in concentrations two to three times th plasma level no influence occurred. Higher concentrations of Ca2+ (10-25 mmol/l) in the metrizamide or C29 solutions resulted in increased albuminuria.

Albuminuria↗
PubMed1980

Effects of contrast media on circulating blood volume. A comparative investigation of various sites of injection.

Changes in the circulating blood volume following injection of different contrast media and at different sites have been measured in the dog. The results confirm that osmoreceptors in the right atrium play a role for changes in blood volume following injection of a contrast medium. The differential response to individual agents was mainly a function of their osmolality. Atropine appears to moderate the changes.

Animals↗
PubMed1980

Contrast media for computer tomography of the liver.

A simple phantom experiment indicates that the enhancement of abdominal organs should be twice the SD of noise in a CT image. The enhancement of liver tissue by urographic and biligraphic contrast media is analysed in clinical series and animal experiments. Various substances, applied alone and in combination, were investigated. At present, only the infusion technique of urographic media provides a sufficient enhancement of liver tissue.

Animals↗
PubMed1982

Coronary angiography with Iopamidol.

Iopamidol, a new non-ionic contrast medium with low osmolality, was compared with Isopaque Coronar during selective coronary angiography in 16 patients. Iopamidol caused significantly less bradycardia, less ECG changes and less fall in blood pressure than Isopaque Coronar. No subjective adverse effects such as chest pain, vomiting, nausea or sensation of heat occurred. The results indicate that Iopamidol has advantages as a contrast medium for coronary angiography.

Adult↗
PubMed1982

Iopamidol compared with Conray in peripheral angiography.

In patients with arteriosclerotic disease in the legs, peripheral angiography was performed double blind with the non-ionic contrast medium Iopamidol and the ionic medium iothalamate meglumine (Conray 60). Iopamidol caused less subjective adverse effects and less changes in blood pressure.

Aged↗
PubMed1983

Double contrast arthrography of the knee. Comparison between three contrast media.

Meglumine iothalamate (Conray Meglumin), sodium-calcium-meglumine metrizoate (Isopaque Cerebral) and dimeglumine iocarmate (Dimerex), each containing about 280 mg I/ml, were compared in two series of double contrast knee arthrography, 190 and 184 patients each. With Dimerex the mixing of the contrast medium with the synovial fluid was slower than with Conray Meglumin, and a good or fair image quality, as evaluated subjectively, lasted longer. No difference was observed between Isopaque Cerebral and Conray Meglumin, regardless of dosage.

Adolescent↗