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[Circadian rhythm of the free 17-hydroxycorticosteroid content in the blood plasma of neurosurgical patients before and after the surgical intervention].

Study of the daily thythms of free 17-oxycorticosteroids in blood plasma of patients with tumors of the spinal cord and spine, discogenic pain syndrome, and of those who underwent plastic surgery for cranial defects revealed disturbances in the biorhythms of the adrenal cortex in patients with tumors of the spinal cord before operation. The postoperative period in all patients was characterized by the development of a stress reaction and paradoxical-type curves of the daily content of these hormones on the 3rd day with complete restoration of adrenal cortex biorhythms by the 15th day. The patients examined did not require special hormonotherapy.

17-Hydroxycorticosteroids↗
PubMed1977

[Blood plasma level of 17-hydroxycorticosteroids in peridural and combined anesthesia].

Studies of the effect of peridural anesthesia applied as an independent method or together with combined narcosis has proved that peridural anesthesia does not cause adrenocortical tension, maintains, the natural level of adrenocortical secretion, contributes to rapid normalization of corticosteroids level in the postoperative period. The increase of corticosteroids blood level in case of peridural anesthesia, applied together with combined narcosis, should be referred on account of direct effect of ether-oxygen narcosis.

17-Hydroxycorticosteroids↗