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[Information sources on carcinogenic agents].

This work comprises lists of publications and computer data bases available at the Scientific Information Department, The Nofer Institute of Occupational Medicine, Lodz, Poland, containing information on cancer risks resulting from exposure to carcinogenic agents. The following publications have been described: IARC Monographs on the Evaluation of Carcinogenic Risk to Humans; Official lists of carcinogens valid in individual countries; a periodical--Survey of compounds which have been tested for carcinogenic activity; a guide--The Annual Report on Carcinogens, a series on Carcinogens in the Occupational Environment, comprising Information Cards and Monographs; a guide on Carcinogenic Agents, and computer databases, including the INCAR, IRIS, IRPTC, RTECS CHEMINFO factual databases and the CANCER-CD, MEDLINE, TOXLINE, NIOSHTIC and MEDIP bibliographic (or reference) databases. The presented publications and databases may prove helpful in searching for data on identifying and preventing the adverse health effects of environmental and occupational exposure to carcinogens.

Carcinogens↗

PubMiur: a tool for on-line assisted bibliographic researches.

Several kinds of user can be interested in scientific publication references produced by academic organizations. Sometimes references are arranged in HTML pages, separated one for an year, and a database containing them can not be available. Results of executed query using this framework couldn't be satisfying. We developed a web-based system to assist user making query, inside web pages, using different search criteria. The constrain on querying one year at a time and the lack of a database is so overcame.

Databases, Bibliographic↗

Economic analysis of treatment of functional dyspepsia. An assessment of the quality of published studies.

OBJECTIVES: The objective of this study was to assess the quality of economic analysis studies published in the medical and economical literature assessing the clinical management of functional dyspepsia. METHODS: Bibliographic search in the main biomedical databases, in articles from bibliographic references, health technology assessment reports, and in gray literature. A specific protocol with economic and clinical items was designed for the evaluation. RESULTS: Overall, 18 of 162 studies met the inclusion criteria for the assessment. The compared treatment options were very diverse. The main methodologic deficiencies were in perspective of analysis, inclusion of indirect costs, and sources of clinical information. CONCLUSIONS: Specific checklists with clinical and economical items may help to better assess the quality of economic analysis in the field of functional dyspepsia. The methodologic rigor in the application of economic analysis techniques, as well as the use of appropriate clinical outcome measures, is essential to guarantee the reproducibility of the studies.

Bibliometrics↗

Retrieving research studies: a comparison of bibliographic and full-text versions of the New England Journal of Medicine.

It has been established that subject searches of medical full-text databases obtain higher recall than subject searches in a bibliographic database. In this study we attempted to determine if the same rule might apply when searching for a non-subject parameter such as study design. A simultaneous search of bibliographic and full-text records from the New England Journal of Medicine provided data on the number of items retrieved by each kind of search. Filtering strategies were created for 5 different study types: randomized controlled trials, other clinical trials and prospective studies, cohort studies, longitudinal and follow-up studies, and multicenter studies. The point of the study was to compare the numbers of items retrieved from the bibliographic database, MEDLINE, and those retrieved from the full-text version of NEJM, and to examine the unique access points available in each file. For all the study types the full-text file retrieved a larger number of records than MEDLINE, most of which were retrieved because of methodology terms found in the text but not in the title or abstract. In MEDLINE, descriptors and publication types, two value-added fields supplied by indexers, retrieved 11-89% more than title and abstract alone.

Abstracting and Indexing↗

The Eukaryotic Promoter Database EPD.

The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of experimentally characterised eukaryotic POL II promoters. The underlying definition of a promoter is that of a transcription initiation site. All information presented in EPD results from an independent evaluation of primary experimental data shown in the biological literature. Sequences flanking transcription initiation sites are indirectly given by pointers to EMBL sequences. The annotation part of a promoter entry includes description of the promoter-defining evidence, cross-references to other databases, and bibliographic references. Being designed as a resource for comparative sequence analysis, EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets. The database is available through the World Wide Web at URL http://cmpteam4.unil.ch

Animals↗

[Information retrieval on ethical problems by online consultation of bioethics bibliographic data bases].

In an age when the ever-expanding limits of sciences are requiring an adjustment of moral principles and values, the Bioethics file is an essential tool for those who are in need of updated guidelines on bioethical issues. This database--produced by the Kennedy Institute of Ethics (KIE) in collaboration with the National Library of Medicine (NLM)--is distributed online by different hosts and is also available in print version and on CD-ROM. Structure and contents of the online version of the Bioethics file searchable through MEDLARS are described in details.

Bioethics↗

[Survey of bibliographic facilities offered in departments of anesthesia and intensive care of French univeristy hospitals].

OBJECTIVES: We assessed bibliographic facilities offered in departments of anaesthesia (DA) belonging to university hospitals in metropolitan France. METHODS: We mailed a questionnaire to the 76 heads of DA belonging to university hospitals in France to assess: a) which journals dealing with anaesthesia, analgesia, and critical care were available, on site, for consultation; b) whether a medical library existed within the institution; and c) whether all bibliographic informations required by any DA collaborators were charged to the institution. RESULTS: We received 67 replies (87%). High impact factor revues had the widest availability rates--Anesthesiology: 67 DA (100% of responses)--Anesthesia Analgesia: 66 DA (98.5%)--the British Journal of Anaesthesia: 63 DA (94%). The Annales Françaises d'Anesthésie et de Réanimation were available in 66 DA (98.5%). Ten journals in French were variably available--no journal: 1 DA (1.5%)--1 journal: 19 DA (28%)--2 journals: 34 DA (51%),--3 journals: 10 DA (15%)--4 journals: 3 DA (4%). Revues dealing with anaesthesia in specialised surgery were diversely available--neurosurgery: 7 DA (10%)--paediatrics: 10 DA (15%)--obstetrics: 11 DA (16%)--cardiovascular: 26 DA (39%). Revues dealing with pain management, regional anaesthesia or critical care were available in 29 DA (43%), 32 DA (47%), and 59 DA (91%), respectively. The European Journal of Anaesthesiology was available in 40 DA (60%). Thirty-nine DA (58%) took charge of all bibliographic informations required. No medical library existed in 4 university hospitals (6%). CONCLUSION: DA offers a wide variation in bibliographic facilities in French university hospitals.

Anesthesia Department, Hospital↗

The Eukaryotic Promoter Database (EPD): recent developments.

The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in nucleotide sequence entries. The annotation part of an entry includes description of the initiation site mapping data, cross-references to other databases, and bibliographic references. EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets for comparative sequence analysis. Recent efforts have focused on exhaustive cross-referencing to the EMBL nucleotide sequence database, and on the improvement of the WWW-based user interfaces and data retrieval mechanisms. EPD can be accessed at http://www.epd.isb-sib.ch

Algorithms↗

Librarians, clinicians, evidence-based medicine, and the division of labor.

Have librarians promoted end user searching to the detriment of the profession and promoted clinical inefficiency from causally trained health practitioners? Issues related to the complexity of bibliographic retrieval in the networked environment are explored within the context of evidence-based medicine and the division of labor.

Databases, Bibliographic↗