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At least 919 records · Page 51Linked to original sources
PubMed1983

Effect of increased intracranial pressure on the blink reflex in cats.

During an acute increase in ICP produced by balloon inflation three different phases could be observed. In the first phase (ICP 40-50 mm Hg) the latencies of R 1 and R 2 showed an initial decrease followed by increase in latency. In the second phase (ICP 50-70 mm Hg) R 2 disappeared, whereas R 1 showed marked alterations, prolongation of the latency and duration, and a decreasing amplitude. In the third phase no response could be evoked. The pathophysiological observations correlated with the morphological alterations. Two ischaemic zones with BBB damage which "transsected" the mesodiencephalic and pontomesencephalic border were found. The results suggest that the disappearance of R 2 depends on rostral damage, whereas alteration of R 1 is caused by a pontomesencephalic lesion.

Animals↗
PubMedDate not supplied

The fear potentiated startle effect. Blink reflex modulation as a result of classical aversive conditioning.

A differential conditioning study examined whether an acoustic startle probe, presented during extinction of an aversively conditioned visual stimulus, potentiated the reflex eyeblink response in humans and whether this potentiation varied with the change in affective valence of the conditioned stimulus. Sixty college students were randomly assigned to view a series of two slides, depicting either unpleasant/highly arousing, unpleasant/moderate arousing, neutral/calm, pleasant/moderate arousing or pleasant/highly arousing scenes and objects (duration: 8 sec). During preconditioning (8 trials) and extinction (24 trials) acoustic startle probes (white noise bursts [50 ms; 95 dBA] were administered during and between slide presentation). During acquisition (16 trials) CS+ was reinforced by an electric shock. Startle response magnitudes significantly increased from preconditioning to extinction and were substantially larger to CS+. Conditioned startle reflex augmentation linearly increased with the pleasantness of the slides. Furthermore, subjects showed a greater post-conditioning increase of judged aversiveness to slides that they had previously reported to be more pleasant, exactly paralleling the startle reflex results.

Adult↗
PubMed1983

A pretectofacial projection in the cat: a possible link in the visually-triggered blink reflex pathways.

A direct projection from the pretectum to the facial motor nucleus was shown to exist in the cat by the anterograde and retrograde horseradish peroxidase (HRP) methods. Pretectofacial fibers arise from the olivary pretectal nucleus and end mainly in the dorsal division of the facial motor nucleus, bilaterally, with a contralateral predominance. It is known that the olivary pretectal nucleus receives retinal fibers, and that the dorsal division of the facial motor nucleus contains orbicularis oculi motoneurons. Thus, the pretectofacial fibers are assumed to cause protective lid closure with certain visual stimuli.

Animals↗